1.A Clinical Observation on Tumors of the Genito-urinary Tract.
Korean Journal of Urology 1976;17(1):19-24
122 cases of the genitourinary tract tumors admitted to the Department of Urology, National Medical Center, during the period, Aug. 1968 to July 1975 and the followings are the results. 1. 122-cases(12.8%) were tumor patient among 954 (male 702, female 252) Total admitted patients during 7 years. 2. Age distribution was from 5 months to 83 years showing the highest incidence in the 7th decade (30.3%) and cases over 41 years of age were 99(81.1%) 3. Sex ratio of male and female was 5.4:1(103:19) 4. In 122 cases, 42 cases{34.4%) were benign, 77 cases(63. 1%) were malignant and remainders were uncertain pathologically. 5. Among 122 cases, 57 cases(46.7%) were vesical, 35 cases(28.7%) prostatic, 19 cases(15.6%) renal, 5 cases(4.1%) penile. 3 cases(2.5%) testicular and 3 cases(2.5%) were urethral tumors. 6. Operations were performed in 114 patients (93.5%).
Age Distribution
;
Female
;
Humans
;
Incidence
;
Male
;
Sex Ratio
;
Urology
2.Antiviral Effect of Antisense Phosphorothioate Oligonucleotides Targeted to Herpes Simplex Virus.
Yoo Chul LEE ; Soo Jee KIM ; Yoo Jin CHO
Journal of the Korean Society for Microbiology 1999;34(3):233-243
To search the effective antisense oligonucleotide that inhibit the growth of Herpes simplex virus type 1 (HSV-1), six kinds of phosphorothioate oligodeoxynucleotides (S-ODNs) were synthesized and the antiviral activity was assessed by measuring cytopathic effect in Vero cells infected with HSV-1. Of the three dodecamer S-ODNs, cornplernentary to the translation initiation site of IE2 (AS2) and scrambled S-ODN (AS1) showed more significant antiherpetic activity than AS4 complementary to the IE4. Accordingly, the antiviral effect of dodecamer S-ODN was not specific. In contrast to the no inhibitory effect of sense strand S-ODN of ICP8 (AS6), two S-ODNs complementary to the translation initiation site of ICP8 (AS3) and that of IE1 (AS5) showed potent antiherpetic activity assessed in vitro HSV-1 virus yield assay. Antiherpetic effect of AS3 was decreased in proportion to the addition of AS6. The synthesis of viral protein ICPS and IE1 were inhibited in AS3 and AS5 treated HSV-1 infected Vero cells, respectively. These findings suggest that antiherpetic effect of AS3 is specifically mediated by targeting ICPS. S-ODNs had no effect on Vero cell viability. The data suggest that the 19-mer S-ODNs may be effective in antiviral chemotherapy.
Drug Therapy
;
Herpes Simplex*
;
Herpesvirus 1, Human
;
Oligodeoxyribonucleotides
;
Phosphorothioate Oligonucleotides*
;
Simplexvirus*
;
Vero Cells
3.A Comparative Study on the Interlaboratory Triglyceride Determination.
Myung Jin KIM ; Tae Young KIM ; Won Sang YOO
Korean Circulation Journal 1979;9(1):23-25
Quality control survey was done on the plasma triglyceride determination of six laboratories and following results were obtained. 1) Coefficients of variation were less than 5% in 3 laboratories and over 10% in one laboratory. 2) High interlaboratory variation was inferred from the mean values ranging from 104.0~136. 4mg% (sample A) with enzyme method and 44.7~65.3 (Sample B) with acetylaceton method. 3) Establishment of normal plasma triglyceride level in Koreans and supervised quality control by the authority seemed to be urgent.
Plasma
;
Quality Control
;
Triglycerides*
4.A clinical study for malunited fractures of the distal end of the radius.
Chong Il YOO ; Yong Jin KIM ; Yeong Ho KIM
The Journal of the Korean Orthopaedic Association 1991;26(3):779-788
No abstract available.
Fractures, Malunited*
;
Radius*
5.A study on the quantitative evaluation of hoarseness using sonograph.
Young Sam YOO ; Kwang Hyun KIM ; Jin Young KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(1):148-158
No abstract available.
Evaluation Studies as Topic*
;
Hoarseness*
6.Clinical Analysis of Patients with Acute Dizziness Visiting an Emergency Center.
Hunk Dong KIM ; Su Jin YOO ; Jae Hwang PARK
Journal of the Korean Society of Emergency Medicine 2000;11(4):546-554
BACKGROUND: Dizziness is a common complaint in patients presenting at emergency departments. Dizziness is difficult to assess because it is a subjective complaint that cannot be measured. We report a clinical analysis of patients with acute dizziness: type, duration, symptom, incidence, etc. METHODS: We reviewed the clinical details and the results of vestibular function tests for 106 acutely dizzy patients who visited the Emergency Department of Wonkwang University Hospital during the period of Jul. 1999 through Dec. 1999. RESULTS: The most common etiology of acute dizziness was the peripheral vestibular system(66%). The most common disease of the peripheral vestibular system was benign paroxysmal positional vertigo(52.9%), and the second most one was vestibular neuronitis(42.9%). In the central nervous system, cerebrovascular accident(63.6%) was the most common cause. All of the patients had experienced a previous vertigo attack, and 42.4% of them had frequent attacks. Dizziness of the cochlear systems were usual in peripheral vertigo. The usual underlying diseases related with vertigo were hypertension, cerebral infarction and diabetes mellitus. CONCLUSION: Dizziness is a complex and frustrating symptom with numerous possible causes. In case with suspected central disorders, CT and MRI have a great diagnostic significance.
Central Nervous System
;
Cerebral Infarction
;
Diabetes Mellitus
;
Dizziness*
;
Emergencies*
;
Emergency Service, Hospital
;
Humans
;
Hypertension
;
Incidence
;
Magnetic Resonance Imaging
;
Vertigo
;
Vestibular Function Tests
7.A Case of Dichloromethane Intoxication Following Ingestion.
Jin Hyun YOO ; Chan Woong KIM ; Koo Young JUNG
Journal of the Korean Society of Emergency Medicine 1999;10(1):128-132
The Dichloromethane(methylene chloride) is a highly volatile liquid used as a solvent, extraction medium, and paint remover. The most significant route of intoxication to dichloromethane is generally inhalation at work site or home, but ingestion is rare. The main toxicological harvard insults from in vivo conversion of dichloromethane to carbon monoxide. We present a case of dichloromethane intoxication following ingestion. A 71 years old male patient ingested 60-70cc of dichloromethane was brought to emergency department after stomach washout via nasogastric tube at other hospital. On arrival at emergency department(approximately 19 hours after ingestion), he was stuporous with a blood pressure 140/90mmHg, heart rate of 92 beats/min, dyspneic, respiratory rate of 24/min and body temperature 36.8 degrees C. His Pupils were isocoric, miotic, and sluggishly reactive. There were mucosal bums and significant secretion in oral cavity. On auscultation, breathing sound was coarse without role on both lung field. The COHb levels were 6.3%at 32 hours after ingestion and normalized to 0.6%at 44 hours after ingestion. Patient was transfered to intensive care unit and supportive care was started with 100% oxygen. On ingestion 4th day, chest X-ray showed pulmonary edema and acute respiratory distress syndrome developed. Patient regained the consciousness on the 11th day. On the 30th day, respiratory function improved and the ventilator was removed. Alveolitis and mild pulmonary fibrosis developed and mild dyspnea was continued. On the 36th day, gastroscopic examinations showed ulceration of esophagus and stomach. On the 76th day, patient was discharged after pulmonary rehabilitation.
Aged
;
Auscultation
;
Blood Pressure
;
Body Temperature
;
Carbon Monoxide
;
Consciousness
;
Dyspnea
;
Eating*
;
Emergencies
;
Emergency Service, Hospital
;
Esophagus
;
Heart Rate
;
Humans
;
Inhalation
;
Intensive Care Units
;
Lung
;
Male
;
Methylene Chloride*
;
Mouth
;
Oxygen
;
Paint
;
Pulmonary Edema
;
Pulmonary Fibrosis
;
Pupil
;
Rehabilitation
;
Respiratory Distress Syndrome, Adult
;
Respiratory Rate
;
Respiratory Sounds
;
Stomach
;
Stupor
;
Thorax
;
Ulcer
;
Ventilators, Mechanical
;
Workplace
8.Carcinoid Tumor Arising in a Horseshoe Kidney: A case report.
Yoo Jin KIM ; Bang HUR ; Man Ha HUR
Korean Journal of Pathology 1996;30(12):1129-1137
Primary carcinoid tumor of the kidney is extremely rare ; only 29 previous reports have been described in the world literature, 3 cases of which were known to arise in horseshoe kidneys. Because of the scarcity of primary renal carcinoid tumor, its clinicopathologic features and prognosis are not well characterized, and its histogenesis is unknown. We present a case of primary carcinoid tumor arising in the horseshoe kidney of a 43-year-old man. The lesion is morphologically identical to those of gastrointestinal or respiratory tracts. In addition, this tumor contains clusters of intestinal epithelium with goblet cells and mature bony trabeculae. The cytoplasm of the tumor cells are immunoreactive for keratin, NSE, and synaptophysin, but are negative with Grimelius and Fontana-Masson stains. Membrane-bound cytoplasmic neurosecretory granules are observed by electron microscopic examination. This is the first case of primary renal carcinoid tumor arising in a horseshoe kidney documented in Korea. We describe the gross features, light and electron microscopic, and immunohistochemical findings of renal carcinoid and review the literature, with speculations on the possible histogenesis of this unusual neoplasm.
9.Growth hormone response to peripheral infusion of clonidine in patients with panic disorder, major depression and alcohol dependence(1 ).
Joo Jin KIM ; Dong Hyun AHN ; Tae Hyuk YOO
Journal of Korean Neuropsychiatric Association 1992;31(3):488-498
No abstract available.
Clonidine*
;
Depression*
;
Growth Hormone*
;
Humans
;
Panic Disorder*
;
Panic*
10.Aneurysm of Splenic Artery: A Case Report.
Huck Dong KIM ; Su Jin YOO ; Jae Hwang PARK
Journal of the Korean Society of Emergency Medicine 1999;10(3):499-503
Aneurysm of the splenic artery are the third most common intra-abdominal aneurysm, following aneurysms of the infrarenal aorta and iliac arteries. Splenic artery aneurysms (SAA) are the most frequent visceral artery aneurysms and account for more than two thirds of all lesions. Incidence of SAA are rare clinical entities(0.01-0.2%) that carry risk of rupture and fatal hemorrhage(35-100%). Fibroblastic dysplasia and atherosclerosis is fecund in the majority, and the fact that these aneurysms developes more commonly in female. Most patients are asymptomatic and the diagnosis is generally made incidentally. The treatment of patient with known SAA is dictated by several factors, including location, age, sex, present of symptom, size, pregnancy. We report ruptured splenic artery aneurysm with hemoperitoneum and review of the literature.
Aneurysm*
;
Aorta
;
Arteries
;
Atherosclerosis
;
Diagnosis
;
Female
;
Fibroblasts
;
Hemoperitoneum
;
Humans
;
Iliac Artery
;
Incidence
;
Pregnancy
;
Rupture
;
Splenic Artery*