1.A Clinical Study on the Posterior Subcapsular Cataracts in Childhood Nephrotic Syndrome.
Dong Kyu JIN ; Ja Wook KOO ; Hae Il CHEONG ; Yong CHOI ; Kwang Wook KO ; Jong Hoon LEE ; Young Suk YU
Journal of the Korean Pediatric Society 1990;33(8):1097-1103
No abstract available.
Cataract*
;
Nephrotic Syndrome*
2.Radiation Exposure of Operator during Various Interventional Procedures.
Jin Wook CHUNG ; Jae Hyung PARK ; Joon Koo HAN ; In Kyu YU ; Wee Saing KANG
Journal of the Korean Radiological Society 1994;30(2):265-270
PURPOSE: To investigate the levels of radiation exposure of an operator which may be influenced by the wearing an apron, type of procedure, duration of fluoroscopy and operator's skill during various interventional procedures MATERIALS AND METHODS: Radiation doses were measured both inside and outside the apron(0.5mm lead equivalent) of the operator by a film badge monitoring method and the duration of fluoroscopy was measured in 96 procedures prospectively. The procedures were 30 transcatheter arterial embolizations (TAE), 25 percutaneous transhepatic biliary drainages (PTBD), 16 stone removals (SR), 15 percutaneous needle aspirations (PCNA) and 10 percutaneous nephrostomies(PCN). To assess the difference of exposure by the operator's skill, the procedures of TAE and PTBD were done separately by groups of staffs and residents. RESULTS: Average protective effect of the apron was 72.8%. Average radiation exposure(unit:micro Sv/procedure) was 23.3 in PTBD by residents, 10.0 in PTBD by staffs, 10.0 in SR, 8.7 in TAE by residents, 7.3 in TAE by staffs, 9.0 in PCN and 6.0 in PCNA. Average radiation exposure of residents were 1.9 times greater than those of staffs. CONCLUSION: Radiation exposure was not proportionally related to the duration of fiuoroscopy, but influenced by wearing an apron, various types o[procedure and operator's skills.
Aspirations (Psychology)
;
Film Dosimetry
;
Fluoroscopy
;
Needles
;
Pregnenolone Carbonitrile
;
Proliferating Cell Nuclear Antigen
;
Prospective Studies
3.Treatment of Fracture of the Tibial Intercondylar Eminence with Arthroscopic Pull-Out Suture.
Jung Han YOO ; Yong Wook PARK ; Jin Sub KIM ; Yung Khee CHUNG ; Sun O YU
Journal of the Korean Knee Society 1998;10(1):50-55
The purpose of this study is to demonstrate the effectiveness of arthrocopic treatment for the avulsion fracture of intercondylar eminence of the tibia and of the technique of arthroscopically assisted reduction and fixation through pull-out suture method. Between January 1995 and May 1997, three patients were underwent arthroscopic reduction and suture fixation for type 0 of avulsion fracture of intercondylar eminence of tibia and were followed up. The result of two patients were graded as normal and one as nearly normal by the criteria of the International Knee Documentation Committee(IKDC) rating scale. The advantages of this technique include no retained hardware and ability to treat comminuted fracture(type g ). We describe technique of arthroscopic reduction and suture fixasion for displaced avulsion fractures, including those with comminution of intercondylar eminence of tibia.
Humans
;
Knee
;
Sutures*
;
Tibia
4.A Case of Arteriovenous Hemangioma showing Darier's Sign.
Hee Joon YU ; Sang Jin KWON ; Ji Hyeung CHO ; Hong Yoon YANG ; Yong Wook PARK ; Se Jin JANG
Korean Journal of Dermatology 1997;35(1):209-213
We experienced a case of arteriovenous hemangioma showing Dariers sign on the forehead of a 43-year-old man. He presented with a single, 1 * 1.5cm sized, violaceous, asymptomatic nodule with a history of an intermittent wheal at the lesional site. This skin lesion showed Dariers sign clinically and proliferation of mast cells histopathologically with the punch biopsy specirnen suggesting urticaria pig- mentosa. Howerer, we could diagnose it as a arteriovenous hemangioma on complete excision, as the specimen showed arteriovenous proliferation with increased mast cells in a perivascular pattern. This case showed confusing clinical signs and showed the importance of complete excision for the diagnosis of a small skin tumor especially when a vascular proliferating tumor is suspected.
Adult
;
Biopsy
;
Diagnosis
;
Forehead
;
Hemangioma*
;
Humans
;
Mast Cells
;
Skin
;
Urticaria
6.Embryotoxicity and Toxicokinetics of the Antimalarial Artesunate in Rats.
Moon Koo CHUNG ; Wook Joon YU ; Jin Soo LEE ; Jong Hwa LEE
Toxicological Research 2013;29(1):27-34
This study was conducted to investigate the potential embryo-fetal toxicity and toxicokinetics of the antimalarial agent artesunate (ARTS) in Sprague-Dawley rats. Pregnant rats were administered ARTS daily from gestational day 6~15 via oral gavage, at test doses of 0, 2, 4, or 8 mg/kg (22 females per group). The fetuses were examined for external, visceral, and skeletal abnormalities on gestational day 20. With regard to the dams, there were no deaths, treatment-related clinical signs, changes in body weight, or food intake in any of the treatment groups. There were no treatment-related gross findings at necropsy in any treatment group. In the 8 mg/kg group, there was a decrease in gravid uterine weight and in the weight of female fetuses. There was also an increase in fetal deaths (primarily late resorptions) and an increase in post-implantation losses (37%) at 8 mg/kg. An increase in the incidence of visceral and skeletal variations at 4 and 8 mg/kg was observed. These defects included minor changes in the appearance of the kidney and thymus, as well as absent ribs or thoracic vertebrae. Toxicokinetics were assessed in a parallel study, using 4 mated females per group. Using liquid chromatography-mass spectrometry (LC-MS) analysis, the concentration of ARTS and its metabolite dihydroartemisinin (DHA) were quantified in plasma from rats on gestational days 5, 6, 10, and 15. Amniotic fluid was assayed for ARTS and DHA on gestational day 15. There was evidence of rapid conversion of ARTS to the metabolite DHA in maternal plasma, since ARTS could not be consistently detected in plasma at the three doses tested. ARTS and DHA were not detected in amniotic fluid at gestational day 15, indicating limited placental transfer of the two agents. The embryo-fetal no-observable-adverse-effect level (NOAEL) of the test item was considered to be 8 mg/kg/day for dams, and 2 mg/kg/day for embryo-fetal development.
Amniotic Fluid
;
Animals
;
Artemisinins
;
Body Weight
;
Eating
;
Female
;
Fetal Death
;
Fetus
;
Humans
;
Incidence
;
Kidney
;
Plasma
;
Rats
;
Rats, Sprague-Dawley
;
Ribs
;
Spectrum Analysis
;
Thoracic Vertebrae
;
Thymus Gland
7.A Clinical Experience of Subcutaneous Bronchogenic Cyst.
Ye Jin LEE ; Duck Kyoon AHN ; Hee Joon YU ; Won Mi LEE ; Yong Wook PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2001;28(2):175-178
Bronchogenic cyst is a congenital anomaly of the embryolgic foregut. A bronchogenic cyst is thought to arise from developing lung bud structure in the 7th week of gestation. Subcutaneous bronchogenic cyst is developed from isolated lung parenchyme during cell migration. Sometimes the fistula is formed between cyst and epidermis. Histologically, fistula tract is lined with sebaceous gland, which is the evidence of embryologic anomaly of cyst. The most common extrapulmonary location of bronchogenic cyst is mediastinum. Subcutaneous location is uncommon. Subcutaneous bronchogenic cyst is commonly located in suprasternal notch followed by the presternal area, neck and scapula. Subcutaneous bronchogenic cyst is predominantly found in male and the ratio is four to one. Clinically the cutaneous presentation vary from nodular swelling, sinus tract ostium to papillomatous lesion. The differential diagnosis of bronchogenic cyst include branchial cleft cyst, thyroglossal duct cyst, cutaneous ciliated cyst and mature cystic teratoma. The diagnosis of subcutanoeus cyst is entirely dependent on the histologic feature. Bronchogenic cyst is lined with ciliated pseudostratified columar epithelium of respiratory origin. Underlying wall is surrounded by the smooth muscle, cartilage and seromucinous gland. This report is on a subcutaneous bronchogenic cyst in a 5-years-old male without fistula tract. The cyst is 5 x 4 x 3 cm in size and histolgically shows the typical feature of bronchogenic cyst.
Branchioma
;
Bronchogenic Cyst*
;
Cartilage
;
Cell Movement
;
Diagnosis
;
Diagnosis, Differential
;
Epidermis
;
Epithelium
;
Fistula
;
Humans
;
Lung
;
Male
;
Mediastinum
;
Muscle, Smooth
;
Neck
;
Pregnancy
;
Scapula
;
Sebaceous Glands
;
Teratoma
;
Thyroglossal Cyst
8.Imaging Findings of Osler-Weber-Rendu Disease Involving the Liver.
Dong Ho LEE ; Jin Wook CHUNG ; Jae Hyung PARK ; In Kyu YU ; Hye Kyung YOON ; Guk Myeong CHOI
Journal of the Korean Radiological Society 1995;32(6):943-946
A 62-year-old woman with hereditary hemorrhagic telangiectasia(HHT) or Osler-Weber-Rendu disease involving the liver is presented. Imaging findings including color Doppler sonograph and CT findings are described.
Female
;
Humans
;
Liver*
;
Middle Aged
9.Experimental Study on High-Resolution CT of Pulmonary Oil Embolism Induced by LipiodoI-Adriamycin Emulsion.
Jung Gi IM ; Jin Wook CHUNG ; Jae Hyung PARK ; Man Chung HAN ; Kyung Mo YEON ; In Kyu YU ; Dae Young YOON
Journal of the Korean Radiological Society 1994;31(6):1051-1060
PURPOSE: To elucidate high-resolution CT(HRCT) findings and their pathologic basis in pulmonary oil embolism induced by LipiodoI-Adriamycin emulsion. MATERIALS AND METHODS: Pulmonary oil embolism was induced by infusing LipiodoI-Adriamycin emulsion through a peripheral vein in twelve Yorkshire pigs. Serial HRCT scans were performed on 2rid, 4th, 7th, 14th, and 28th day after the procedure. The pigs were sacrificed immediately after HRCT and histologic specimens were prepared in the same plane and level with HRCT. RESULTS: The basic pathology was reversible hemorrhagic edema of the lung. On HRCT, intraalveolar hemorrhage and edema in the acute stage manifested as ground-glass opacity or air-space consolidation of the whole secondary Iobule. The lesions were predominantly distributed over the dependent posterior lung fields because the specific gravity of Lipiodol is 1.28. Interlobular septal thickening due to edematous fluid collection was also associated. With the elapse of time, the extent and severity of the acute lesions resolved and, sometimes, changed into small nodular opacities. Pulmonary opacity was most severe on the post-embolization 2nd day and completely resolved within 2 weeks. CONCLUSION: Pulmonary embolization of LipiodoI-Adriamycin emulsion causes reversible hemorrhagic edema of the lung and Lipiodol toxicity seems to play a major role. HRCT findings of pulmonary oil embolism are quite different from those of pneumonia and pulmonary metastasis, which suggests the possibility of clincal application.
Edema
;
Embolism*
;
Ethiodized Oil
;
Hemorrhage
;
Lung
;
Neoplasm Metastasis
;
Pathology
;
Pneumonia
;
Specific Gravity
;
Swine
;
Veins
10.Eosinophilic Myocarditis Associated with Hypereosinophilia.
Jin Sook RYU ; In Whan SEONG ; Jae Joong KIM ; Eun Sil YU ; Seong Wook PARK ; Seung Jung PARK ; Jong Koo LEE
Korean Circulation Journal 1991;21(3):626-632
A variety of disease states are marked by prolonged and profound eosinophilia associated with localized or widespread eosinophilic infiltrates. Cardiac involvement maybe a major cause of morbidity and mortality of this disease. We report a case of acute peri-myocarditis with eosinophilia, which was confirmed as eosinophilic myocardilic myocarditis by endomyocardial biopsy.
Biopsy
;
Eosinophilia
;
Eosinophils*
;
Mortality
;
Myocarditis*