No abstract available.

No abstract available.
Diabetes Complications* ; Humans ; Physicians, Family*

No abstract available.
Classification* ; Diabetes Mellitus* ; Diagnosis*

The square face with prominent mandibular angles projects a strong and musculine impression, which is not preferred by most Koreans(may be orientals). Therefore, requests for contouring the prominent mandibular angle are much more common in the orient than in the west. In our study, we treated seven patients with esthetic problem due to prominent mandibular angle using two-step method with intraoral approach via trans- submandibular channel. The advantages of this method are easy measuring, minimized surgical trauma and shortening of the operation time by facilitation of instrumenial application via trans-sumandibular channel.
Humans

No abstract available.
Korea* ; Tuberculosis*

PURPOSE: The relationship between altered HLA expressions and cervical carcinogenesis is not fully elucidated. MATERIALS AND METHODS: The histological evaluation comprised of 21 microinvasive squamous cell carcinoma (SCC), 26 invasive SCC, 3 microinvasive adenocarcinoma and 9 invasive adeno carcinoma of cervix. We used monoclonal antibodys (mAbs) to HLA class I beta2-microglobulin (L368), HLA class I B/C heavy chains (HC-10) and HLA class II heavy chain (LG II-612.14). RESULTS: In tissues from microinvasive SCC, the expressions of B/C heavy chains and class II heavy chain were significantly decreased. The expressions of beta2-microglobulin, B/C chains, and class II heavy chain in SCC were all significantly decreased. Especially, in the metastatic tissue from the same patient, the expressions of beta2-microglobulin and B/C chains showed to be somewhat decreased compared to those in primary tumor tissues, and the expression of class II heavy chain was decreased further than that in primary lesion. In primary invasive adenocarcinoma, the expression of B/C chains was significantly decreased. CONCLUSION: These results suggest that alterations of HLA class I and II expressions seem to occur at a particular step in tumor development and depend on tissue types: when the tumor becomes invasive and starts to metastasize.
Adenocarcinoma ; Carcinogenesis ; Carcinoma, Squamous Cell ; Cervix Uteri ; Female ; Humans ; Uterine Cervical Neoplasms

No abstract available.
Thymidine

In order to investigate the main factor of pathogenicity in V. mimicus, we have studied the toxic effects of j3-hemolysin produced by V. mimicus. The purified hemolysin of V. mimicus was active erythrocytes from three animal species including mouse, rabbit and rat, but the hemolysin was most active against rabbit erythrocyte. The hemolysin lysed cultured cell and killed mouse. Rapid death of mouse was observed with rather small doses of the toxin. Intravenous injection of 20 mg of the purified toxin killed mice within 25 sec. The hemolysin also had a lethal effect on intraperitoneal injection into mice although less than on intravenous injection. Purified hemolysin injected rabbits had large morphological change in jejunum. In electron micrograph of thin sections of the human erythrocytes, cells were threated with the hemolysin at 37 C for 5 min., significant changes were not observed. But after 10 min., hemolysis was observed and after 60 min., complete degradation of human erythrocyte was observed.
Animals ; Cells, Cultured ; Erythrocytes ; Hemolysis ; Humans ; Injections, Intraperitoneal ; Injections, Intravenous ; Jejunum ; Mice ; Rabbits ; Rats ; Vibrio mimicus* ; Vibrio* ; Virulence

BACKGROUND: Reconstitution of hematopoiesis by means of peripheral blood stem cells(PBSC) has been widely used in patients with hematologic malignancies or solid tumors. We analyzed our experiences of PBSC collections with a MCS3p(Haemonetics Corp. Braintree, MA,USA) and investigated factors that may affect the collection of PBSC. METHOD: The forty-seven harvests in 11 cancer patients(median age 48, 4 males: 7 females) were performed during marrow recovery after administration of anticancerous regimens and and hematopoietic growth factors. RESULTS: Median number of WBC & mononuclear cells(MNCs) in preapheresis was 4,700/pl and 1,472/pl, retrospectively. A total of 11.2 x 10'(range 5.4-17.0) MNCs were collected from 7.2 l (5.5-8.9) blood processed per procedure. The mean percentage of CD34 positive cells in the product was 1.9%(0.9-2.9). Collection efficiency was 58.1%. While age of patients or total processed blood volume did not affect for total number of MNC collected, the number of WBCs including MNCs on the day of harvest was an importanr factor for higher yield of MNCs(P<0.05). CONCLUSION: We concluded that Haemonetics MCS3P. Is a fully automated blood cell separator with good collection efficiency for hematopoietic progenitor cells.(Korean J Blood Transfusion 10(1): 35-41,1999)
Blood Cells ; Blood Transfusion ; Blood Volume ; Bone Marrow ; Hematologic Neoplasms ; Hematopoiesis ; Humans ; Intercellular Signaling Peptides and Proteins ; Male ; Retrospective Studies ; Stem Cells*

No abstract available.
Humans* ; Neutrophils* ; Superoxides*