1.A Study of Fluorescence Pattern of Immune Deposits in Bullous Pemphigoid and Epidermolysis Bullosa Acquisita.
Korean Journal of Dermatology 1994;32(4):626-630
Backgraund : Most of the inflammatory bullous lesions in bullous pamphigoid(BP) and epidermolysis bullosa acquisite(EBA) demonstrate similar clinical and histological features. However, the specificities of the autoantibodiea reactive to the dermo-epidermal junction antigeins are different. In these two bullouk dermat loses, there are no remarkable differences in symptomaiology, there are no unique predilection sites for the lesions and they do not usually leave scars after nvolution. Considering these similarities, dermatologists could encounter some clinical confuiion in maling a provisional diagnosis. OBJECTIVE: Authors examined three patients of BP with classic inflammatory bullous eruptions and threa patients of EBA with inflammatory bullous lesions to see if here were any differences in the morphology of the immuno-fluorescence(IF) pattern. METHODS: For direct IF of vertical or semi-vertical sections, perilasional skin was obtained in each patient for indirect IF of horizontal or semi-horizonta1 sections, Ig(bound substrates were prepared from all these autoantibody-positive individuals. All specimens veri; observed at 200/400-magnification fields through an ordinary fluorescence microscopy. RESULTS: Patterns of fluorescence observed by direct IF were characterized as thin-linear in BP and thick/coarse-linear in EBA along the basement membrane zone. On the horizontal section preparations in indirect IF, the patterns of fluorescence were clean-linear in E3P hnd more fluffy-linear in EBA at the dermoepidermal junction, These patterns could be recognized aim/larly in the fields of both 200 and 400-magnification, however each minor differences were not easy to distinguish each other. CONCLUSION: The above findings of subtle differences in the pattern of IF may provide some suggestions to the examiners for the need of differential diagnosis in theae riseases.
Basement Membrane
;
Blister
;
Cicatrix
;
Diagnosis
;
Diagnosis, Differential
;
Epidermolysis Bullosa Acquisita*
;
Epidermolysis Bullosa*
;
Fluorescence*
;
Humans
;
Male
;
Microscopy, Fluorescence
;
Pemphigoid, Bullous*
;
Skin
2.A Study of Fluorescence Pattern of Immune Deposits in Bullous Pemphigoid and Epidermolysis Bullosa Acquisita.
Korean Journal of Dermatology 1994;32(4):626-630
Backgraund : Most of the inflammatory bullous lesions in bullous pamphigoid(BP) and epidermolysis bullosa acquisite(EBA) demonstrate similar clinical and histological features. However, the specificities of the autoantibodiea reactive to the dermo-epidermal junction antigeins are different. In these two bullouk dermat loses, there are no remarkable differences in symptomaiology, there are no unique predilection sites for the lesions and they do not usually leave scars after nvolution. Considering these similarities, dermatologists could encounter some clinical confuiion in maling a provisional diagnosis. OBJECTIVE: Authors examined three patients of BP with classic inflammatory bullous eruptions and threa patients of EBA with inflammatory bullous lesions to see if here were any differences in the morphology of the immuno-fluorescence(IF) pattern. METHODS: For direct IF of vertical or semi-vertical sections, perilasional skin was obtained in each patient for indirect IF of horizontal or semi-horizonta1 sections, Ig(bound substrates were prepared from all these autoantibody-positive individuals. All specimens veri; observed at 200/400-magnification fields through an ordinary fluorescence microscopy. RESULTS: Patterns of fluorescence observed by direct IF were characterized as thin-linear in BP and thick/coarse-linear in EBA along the basement membrane zone. On the horizontal section preparations in indirect IF, the patterns of fluorescence were clean-linear in E3P hnd more fluffy-linear in EBA at the dermoepidermal junction, These patterns could be recognized aim/larly in the fields of both 200 and 400-magnification, however each minor differences were not easy to distinguish each other. CONCLUSION: The above findings of subtle differences in the pattern of IF may provide some suggestions to the examiners for the need of differential diagnosis in theae riseases.
Basement Membrane
;
Blister
;
Cicatrix
;
Diagnosis
;
Diagnosis, Differential
;
Epidermolysis Bullosa Acquisita*
;
Epidermolysis Bullosa*
;
Fluorescence*
;
Humans
;
Male
;
Microscopy, Fluorescence
;
Pemphigoid, Bullous*
;
Skin
3.A study on the cell kinetics of transitional cell carcinoma of the bladder:measurements of DNA content and proliferating cell nuclear antigen.
Jong Bok LEE ; Jin Soo JUNG ; Woo Ho KIM ; Sang Eun LEE
Journal of the Korean Cancer Association 1993;25(3):390-397
No abstract available.
Carcinoma, Transitional Cell*
;
DNA*
;
Kinetics*
;
Proliferating Cell Nuclear Antigen*
4.Antitumor components of the cultured mycelia of calvatia craniformis.
Byong Kak KIM ; Ji Yun KWUN ; Young In PARK ; Jin Woo BOK ; Eung Chil CHOI
Journal of the Korean Cancer Association 1992;24(1):1-18
No abstract available.
5.A Case of Squamous Cell Carcinoma of the Skin Resembling Atypical Fibroxanthoma.
So Young JIN ; Woo Hee JUNG ; Kwang Gil LEE ; Jung Bok LEE
Korean Journal of Pathology 1986;20(2):250-253
Both spindle cell variant of squamous cell carcinoma and atypical fibroxanthoma are most commonly presented as a solitary, often ulcerated nodule, occurring on sun-exposed skin of the elderly. These lesions also share the histologic features of diffuse or indistinct fascicular arrangement of polygonal or pulmp spindle cells. Therefore it is not easy to differentiate immunohistochemistry is done. A case of 73 year old woman with squamous cell carcinoma of the skin resembling atypical fibroxanthoma is presented.
Female
;
Humans
6.Prognostic significance of epidermal growth factor receptor expression in human gastric carcinoma.
Woo Ho KIM ; Sang Yong SONG ; Ki Young CHOI ; Yong Il KIM ; Jin Bok KIM
Journal of the Korean Cancer Association 1993;25(1):78-84
No abstract available.
Epidermal Growth Factor*
;
Humans*
;
Receptor, Epidermal Growth Factor*
7.Clinical Evaluation of Endoscopic Microwave Coagulation Therapy for Upper Gastrointestinal Bleeding.
Jong Su KIM ; Sang Bok LIM ; Jin Hong KIM ; Sung Woo CHO ; Chan Sup SHIM
Korean Journal of Gastrointestinal Endoscopy 1988;8(2):127-132
The hemostatic effect of endoscopic microwave coagulation method for upper gastrointestinal bleeding was evaluated clinically. Hemostasis over 72 hours was achieved in 18 of 20 cases (90%) with upper gastrointestinal bleeding by the endoscopic microwave coagulation method. It is noteworthy that this method was effective in all 4 cases of pulsatile bleeding from exposed vessels. We conclude that this method is useful for emergency endoscopic hemostasis on upper gastrointestinal bleeding, especially bleeding from exposed vessels.
Emergencies
;
Hemorrhage*
;
Hemostasis
;
Hemostasis, Endoscopic
;
Microwaves*
8.Comparison of Patella Retention Versus Resurfacing in Total Knee Arthroplasty: Preliminary report.
Yung Bok JUNG ; Jae Kwang YUM ; Jin Woo LEE ; Eui Chan JANG
The Journal of the Korean Orthopaedic Association 1997;32(7):1475-1482
There is a controversy in patella retention or resurfacing in total knee arthroplasty (TKA) till today. Authors studied 52 cases of 45 patients recieved total knee arthroplasty with patella retention (Group 1, twenty-five cases) or patella resurfacing (Group 2, twenty-seven cases) in patients with osteoarthritis. All operations were done by senior surgeon and the implants used were LCS type (33 cases), AMK type (12 cases), Genesis type (5 cases) and Tricon M type (2 cases). The indications of patella retention were small patella, nearly normal articular cartilage, minimal pre-operative patellofemoral pain, poor patellar bone quality and young patients. Patella retention were performed only with LCS prosthesis, which patella groove of the femoral component is deep and anatomical. The operative approaches used were medial parapatella approach in neutral or varus knee and lateral parapatella approch for severe valgus knee and tilting or lateral subluxation of the patella. The mean follow-up period was 24 months (range 12 months to 5 years). The method for clinical evaluation was Hospital for Special Surgery (HSS) knee scoring (consisted of pain, function, range of motion). The method for radiographical evaluation was Knee societys radiologic evaluation system for tibial and femoral alignment, and Keblishs method for patello-femoral congruence. The clinical HSS knee score was average 90.9 points in both groups, and 91.9 points in group 1, 90.0 points in group 2, and there was no statistically difference in HSS knee score between the two groups (P<0.05). The radiologic results had no significant difference in alignment and patello-femoral congruence between the two groups (P<0.05). But the complications were one case of patella fracture, one patella tendon rupture, one anterior instability and two cases of infection in group 2. In conclusion, the results of both groups were satisfactory. We think that it have relation to strict selection of the patients for patella retension and the use of prosthesis that the patella groove of femoral component is deep and anatomical.
Arthroplasty*
;
Cartilage, Articular
;
Follow-Up Studies
;
Humans
;
Knee*
;
Osteoarthritis
;
Patella*
;
Patellar Ligament
;
Prostheses and Implants
;
Rupture
9.Ruptured tibialis posterior tendon in a closed ankle fracture: a case report.
Eun Woo LEE ; Young Bok JUNG ; Soo Yong KANG ; Bong Jin LEE
The Journal of the Korean Orthopaedic Association 1991;26(5):1572-1574
No abstract available.
Ankle Fractures*
;
Ankle*
;
Tendons*