1.A clinical study of the salivary gland tumors.
Journal of the Korean Surgical Society 1991;40(6):697-702
No abstract available.
Salivary Glands*
2.Difference of naloxone effect on pain tolerance between delinquent adolescents with repetitive self injurious behavior and those without self injurious behavior.
Chul Kwon KIM ; Jin Seok CHO ; Won Tan BYOUN
Journal of Korean Neuropsychiatric Association 1992;31(4):767-777
No abstract available.
Adolescent*
;
Humans
;
Naloxone*
;
Self-Injurious Behavior*
3.A Case of Insect Sting by Euponera chosensis.
Jin Sung PARK ; Baik Kee CHO ; Won Koo LEE
Korean Journal of Dermatology 1995;33(1):120-124
Ants(Family Formicidae) are very successful organisms occuring in trernendous numbers worldwide in terrestrial habitats. All ant species may bite, and on species sting. 48 species in 26 genus have been reported in Korea, but only systemic reaction induced by the anti Brachyponera chinersis, has been reported in the Korea terature. A 48 year old man was stung on the neck, abdomen, and dorsum of the hand by flying stinging ants. He experienced moderate pain, burning and itching sensation. Clinical course and histopathologic findings of the lesions caused by the stinging ant was observed without specific treatment. The stinging ants collected from t,he patient.s skin and his house were identified as Euponera chosensis belonging to Subfamily Ponerinae. To the best of our know ledge, this is the first clinical repor of the insect sting by Euponera chosensis in the Korean literature.
Abdomen
;
Ants
;
Bites and Stings
;
Burns
;
Diptera
;
Ecosystem
;
Hand
;
Humans
;
Insect Bites and Stings*
;
Insects*
;
Korea
;
Middle Aged
;
Neck
;
Pruritus
;
Sensation
;
Skin
4.The p53 Mutation and DNA Ploidy in Human Metastatic Breast Cancer.
Seong Jin CHO ; Ae Ree KIM ; Nam Hee WON
Korean Journal of Pathology 1997;31(2):135-144
The p53 gene, one of the tumor suppressor genes, is believed to play an important role through mutation and overexpression in the progression of various human malignant tumors. To compare the p53 mutation status between the primary and metastatic lesions of breast cancers and to investigate the mutational pattern of p53, immunohistochemistry (IHC) and polymerase chain reaction and single strand conformational polymorphism (PCR-SSCP) were performed in 25 cases of breast cancers with paraffin embedded tissue. Mutant protein products or point mutation were detected through IHC or PCR-SSCP method. And flow cytometrical (FCM) analysis were performed in the same paraffin blocks to correlate the DNA ploidy and p53 mutation. The following results are summarized. 1. The detection of the p53 gene mutation and overexpression of the p53 protein were measured in 40% and 48%, respectively, in 25 primary tumors, either or both methods was detected in 64%. 2. A concordance rate of the p53 protein expression between the primary and metastatic lesions of 25 breast cancers was 100%, but the concordance rate of the p53 gene mutation was 72%. 3. The correlation between the p53 mutation and the DNA aneuploidy was not statistically significant (p=0.38) 4. A p53 mutation by IHC or PCR-SSCP was more frequently detected in grade III breast cancers than in grade I or II. 5. Among 5 to 9 exons of the p53 gene, exon 7 was the most frequent mutation spot in this study. 6. Additional mutation of the p53 gene was developed in the three metastatic lesions. With the above results it is suggested that the p53 protein overexpression by immunohistochemistry is not correlated with the p53 mutation by PCR-SSCP. The p53 mutation pattern between the primary and metastatic lesions are not idenitical and an additional point mutation can occur in the metastatic lesion. The DNA aneuploidy is more frequently detected in the cases with the p53 protein overexpression than in the p53 protein negative, but it is not statistically significant.
Aneuploidy
;
Breast Neoplasms*
;
Breast*
;
DNA*
;
Exons
;
Genes, p53
;
Genes, Tumor Suppressor
;
Humans*
;
Immunohistochemistry
;
Mutant Proteins
;
Paraffin
;
Ploidies*
;
Point Mutation
;
Polymerase Chain Reaction
5.The p53 Mutation and DNA Ploidy in Human Metastatic Breast Cancer.
Seong Jin CHO ; Ae Ree KIM ; Nam Hee WON
Korean Journal of Pathology 1997;31(2):135-144
The p53 gene, one of the tumor suppressor genes, is believed to play an important role through mutation and overexpression in the progression of various human malignant tumors. To compare the p53 mutation status between the primary and metastatic lesions of breast cancers and to investigate the mutational pattern of p53, immunohistochemistry (IHC) and polymerase chain reaction and single strand conformational polymorphism (PCR-SSCP) were performed in 25 cases of breast cancers with paraffin embedded tissue. Mutant protein products or point mutation were detected through IHC or PCR-SSCP method. And flow cytometrical (FCM) analysis were performed in the same paraffin blocks to correlate the DNA ploidy and p53 mutation. The following results are summarized. 1. The detection of the p53 gene mutation and overexpression of the p53 protein were measured in 40% and 48%, respectively, in 25 primary tumors, either or both methods was detected in 64%. 2. A concordance rate of the p53 protein expression between the primary and metastatic lesions of 25 breast cancers was 100%, but the concordance rate of the p53 gene mutation was 72%. 3. The correlation between the p53 mutation and the DNA aneuploidy was not statistically significant (p=0.38) 4. A p53 mutation by IHC or PCR-SSCP was more frequently detected in grade III breast cancers than in grade I or II. 5. Among 5 to 9 exons of the p53 gene, exon 7 was the most frequent mutation spot in this study. 6. Additional mutation of the p53 gene was developed in the three metastatic lesions. With the above results it is suggested that the p53 protein overexpression by immunohistochemistry is not correlated with the p53 mutation by PCR-SSCP. The p53 mutation pattern between the primary and metastatic lesions are not idenitical and an additional point mutation can occur in the metastatic lesion. The DNA aneuploidy is more frequently detected in the cases with the p53 protein overexpression than in the p53 protein negative, but it is not statistically significant.
Aneuploidy
;
Breast Neoplasms*
;
Breast*
;
DNA*
;
Exons
;
Genes, p53
;
Genes, Tumor Suppressor
;
Humans*
;
Immunohistochemistry
;
Mutant Proteins
;
Paraffin
;
Ploidies*
;
Point Mutation
;
Polymerase Chain Reaction
6.Prevalence of abnormal thyroid function test and significance of TSH in health examination.
Sang Won JUNG ; Sang Yoo CHANG ; Jung Jin CHO
Journal of the Korean Academy of Family Medicine 1993;14(11):752-759
No abstract available.
Prevalence*
;
Thyroid Function Tests*
;
Thyroid Gland*
7.The marginal accuracy of temporary crown with different matrix.
Tae Hun JU ; Hye Won CHO ; Jin Keun DONG
The Journal of Korean Academy of Prosthodontics 1991;29(2):59-66
No abstract available.
Crowns*
8.The clinical survey of gastric cancer in young adults.
Won Sik LIM ; Young Dong MIN ; Hyun Jin CHO
Journal of the Korean Surgical Society 1991;41(1):22-28
No abstract available.
Humans
;
Stomach Neoplasms*
;
Young Adult*
9.The retention of full veneer gold crown by core material and dental cement.
Jum Im HA ; Hye Won CHO ; Jin Keun DONG
The Journal of Korean Academy of Prosthodontics 1992;30(1):93-101
No abstract available.
Crowns*
;
Dental Cements*
10.A Clinical and Histopathological Study of Tattoos: I. A Clinical Study.
Jin Wou KIM ; Baik Kee CHO ; Won HOUH
Korean Journal of Dermatology 1986;24(2):213-218
128 individuals with tattoos, who were seen during physical examination for conscription from February to May, 1985, were taken for a clinical study of tattoos. The results were as follows: 1. The color of the tattoos were blue-black or light blue. The materials most commonly employed were Chinese ink stick and others were Chinese ink, black ink, blue ink, and smokeless coal powder. 2. The tattoos were made by tattooed themselves or by their friends and sewing needles were punctured to introduce particles of pigment into the skin in all cases. 3. As to the sites of tattoos, left forearm was the favorite(42.4%) and others were left upper arm(28. l%), right forearm(5. 5%), right upper arm(5 1%) etc. 4. Among 271 tattoos of 100 kinds, a rose was most frequently seen(5. 9%) and others were a symbol of love(4. 8%), a butterfly(4.l%), - I (one mind) (3.7%), patience (3. 7%) etc. 5. The complications of tattooing were found in 8. 6p, of the tattooed and they were pyoderma, hypertrophic scar, keloid, lymphadenopathy, post-inflammatory ]yper-and hypopigmentation, and scar formation about tattoos. 6. The removd of tatoos were tried all by tattooed themselves. The most frequent method used was scratching up with a knife and others were cigarette burn, attatchment of bean-curd, rubbing with salt, and chemical burns with hydrochloric acid. etc.
Asian Continental Ancestry Group
;
Burns
;
Burns, Chemical
;
Cicatrix
;
Cicatrix, Hypertrophic
;
Coal
;
Forearm
;
Friends
;
Humans
;
Hydrochloric Acid
;
Hypopigmentation
;
Ink
;
Keloid
;
Lobeline
;
Lymphatic Diseases
;
Needles
;
Physical Examination
;
Pyoderma
;
Skin
;
Tattooing
;
Tobacco Products