1.The research progress on cancer multidrug resistance mechanisms
Practical Oncology Journal 2015;(4):364-367
The multidrug resistance( MDR) has become one of the key factors in the success of chemo-therapy.Thus,overcoming multidrug resistance of tumor has become a pressing matter of the moment for tumor therapy.The mechanism of MDR is a very complicated process,influenced by many factors.Therefore,the tumor multidrug resistance mechanisms in depth study will help to select more appropriate anti-tumor drugs.In this re-view,we described about MDR mechanisms researching progress in recent years.
2.Progress in correlation of long non-coding RNA with breast cancer invasion and metastasis
Tianjin Medical Journal 2015;43(5):566-569
Long non-coding RNA(lncRNA) is a group of functional RNA molecules, which is more than 200 nucleotides in length and lacks ability of encoding protein. The current study indicates that the abnormal expression of lncRNA is closely related with breast cancer progression. Some lncRNA takes part in regulating the process of breast cancer invasion and metastasis. This article reviews the abnormal expression of lncRNA in breast cancer and the relevance with breast cancer invasion and metastasis, which is expected to provide new strategy for breast cancer diagnosis and treatment.
3.The influence of preconditioning for myocardial ischemia on the myocardial infarction and the cytokines in diabetic rats
Chinese Journal of Geriatrics 2001;0(05):-
0 05), While the areas of myocardial necrosis in IP and NIP groups were 64 80% and 32 60%, respectively( P
5.Rehabilitation nursing of 16 patients with femoroacetabular impingement after arthroscopic surgery
Yanhong WEI ; Jin ZHANG ; Jing ZHANG
Chinese Journal of Nursing 2009;44(12):1073-1075
Using the experiences of domestic and other countries on rehabilitation nursing of patients with femoroacetabalar impingement for reference,a balanced rehabilitation procedure was designed and implemented on 16 patients underwent arthroscopic bone forming surgery in acetabulum and femoral head and neck junction.The patients could master the correct metheds of functional exercises.As a result,no postoperative complications occurred.The score of modified Harris hip rating was increased from 62.4 points before surgery to 92.5 points at six months after surgery.
7.Primary malignant melanoma of the maxillary sinus misdiagnosed as bleeding polyp.
Wei HANG ; Gang LIU ; Jin-ling ZHANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(8):688-689
Diagnostic Errors
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Female
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Humans
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Maxillary Sinus
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pathology
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Melanoma
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diagnosis
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Middle Aged
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Paranasal Sinus Neoplasms
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diagnosis
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Polyps
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diagnosis
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pathology
8.Effect of H_2O_2 on transient outword potassium current in the cultured rat hippocampal neurons
Hongwei JIN ; Wei ZHANG ; Xiaoliang WANG ;
Chinese Pharmacological Bulletin 1986;0(06):-
AIM To study the effects of H 2O 2 on transient outward potassium current METHODS Whole cell patch clamp technique was used to record changes of I A in the cultured rat hippocampal neurons RESULTS After exposure to 30 ?mol?L -1 H 2O 2 for 12 h (1) decreased I A current density from (53 8?15 8) PA?PF -1 to (18 5?6 2) PA?PF -1 ( n=10,P
9.Analysis of Acquired Immunodeficiency Syndrome with Manifestation of Chronic Diarrhea in 7 Children
jin, ZHOU ; jing, ZHANG ; xi-wei, XU
Journal of Applied Clinical Pediatrics 2003;0(10):-
Objective To explore the clinical manifestation and laboratory examination of chronic diarrhea in children with acquired immunodeficiency syndrome(AIDS) and analyze the reasons that causes the chronic diarrhea in children.Methods Clinical data of 7 patients (male 4 cases,famale 3 cases)with AIDS with manifestation of chronic diarrhea among the 17 cases were diagnosed as AIDS in Beijing children′s hospital from Jan.1999 to Dec.2006.The time of diarrhea,degree of dinrrhea,characteristic of stool,accompaniment symptom,laboratory examination were retrospectively analyzed.Results The average onset age was 6 years old(from 2-9 years old).The average time of diarrhea was 6 months(from 1-16 months).Four cases main complained with chronic diarrhea,3 cases came to the hospital because of fever,cough and wasting;6 cases with diarrhea,7 cases with malnutrition and anemia,5 cases accompanied hypokalemia and metabolic acidosis,6 cases had delay in growth and development,2 cases with abnormal stool routine exam,1 case with positive stool culture of fungi.All patients were with lower CD4,5 cases with lower CD4/CD8.Conclusions Chronic diarrhea is a common symptom in children with AIDS,and usually accompanied by obvious delay in growth and development,malnutrition and anemia,the reasons that causes the chronic diarrhea are consi-dered to be related with both the opportunistic infection and HIV infection.
10.Study on Fuzzy Mathematical Algorithm Used in Traditional Chinese Medicine Pulse Diagnosis
Wei JIN ; Yan ZHANG ; Jiasheng NI
Chinese Journal of Information on Traditional Chinese Medicine 2016;23(6):1-4
Targeting characteristic information processing of TCM pulse diagnosis, this article studied the application of fuzzy mathematics in objectifying pulse diagnosis. By analyzing limitations of traditional analytic methods, this article offered the scientific evidence of using mathematical algorithm in pulse diagnosis. At the same time, combined with actual clinical data, it also verified the correctness of introduction mathematical algorithm in TCM pulse diagnosis.