1.Distribution of Antibodies Against Hepatitis B virus and Hepatitis C virus in Human Sera.
Journal of the Korean Society of Virology 1997;27(2):129-135
Serum samples from 123 males and 123 females collected by age in 1996 were analyzed for antibodies against surface antigen of Hepatitis B virus and C22-3, C200 antigens of Hepatitis C virus. Sera from the children under the age of 10 showed 30% seropositivity to the surface antigen of Hepatitis B virus, 33.3% in 10~19 year group, 20% in 20~29 year group, 17.6% in 30~39 year group, 3.3% in 40~49 year group, 5.9% in 50~59 year group, 8,3% in 60~69 year group, 2.9% in 70~79 year group, but antibody could not found in 80~86 year group. 12 out of 123 male sera were positive, 19 out of 123 female sera were positive and overall rate of positivity of antibody against surface antigen of Hepatitis B virus was 12.6%. Serum samples from peoples under the age of 30 had not antibody against C22-3, C200 antigens of Hepatitis C virus. The positivity rate was 2.9% in 30~39 year group. 5 out of 30 sera from 40~49 year age group were positive, and 3 positive sera showed extremely high titer (1:524,288) but the titers of two remaining sera were 1:32, 1:8,192 respectively. 5.9% was positive in 50~59 year group, 8.3% in 60~69 year group, 11.8% in 70~79 year group but all negative in 80~86 yea. group. 6 out of 123 male sera were positive (4.9%), 9 out of 123 female sera were positive (7.3%). Overall .ate of positivity of antibody against C22-3, C200 antigen of Hepatitis C virus was 6.1%. None out of 246 sera had both antibodies against Hepatitis B virus and Hepatitis C virus.
Antibodies*
;
Antigens, Surface
;
Child
;
Female
;
Hepacivirus*
;
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis C*
;
Hepatitis*
;
Humans*
;
Male
2.Parathyroid Cysts
Sung Kil LIM ; Jin Sub CHOI ; Cheong Soo PARK
Journal of Korean Society of Endocrinology 1994;9(2):128-135
The parathyroid cyst is a relatively uncommon disease and usually identified during the operation for a presumed thyroid mass. Thirteen cases of parathyroid cyst (2 males, 11 females) treated from 1981 to 1993 were reviewed. Ages ranged from 17 to 59 years(mean, 41 years). Gross measurement of the tumor size varied from 1.0 to 10.0 cm in diameter with a mean of 4.8cm. All of the 13 patients presented with a chief complaint of painless anterior cervical mass. Only one complained of mild symptom of dyspnea and voice change due to huge cyst in paratracheal space. No functional cyst was identified. Diagnostic studies included ^99mTc thyroid scan (n=11), ultrasonography (n=10), computerized tomography (n=4) and fine needle aspiration(FNA) (preoperative, n=4; intraoperative, n=3). All diagnostic precedures but needle aspiration were nonspecific. Cysts were found in right inferior parathyroid(n=4), left inferior parathyroid (n=7), or anterior superior mediastinum (n=2). The FNA of the cyst contents revealed watery clear fluid with elevated parathyroid hormone level and was diagnostic in each cases. Four patients were treated initially with needle aspiration, of which only one patient was successful, and 3 patients who were unsuccessful to needle aspiration and the remaining 9 were effectively treated with surgical extirpation. Our experience suggested that needle aspiration may be of significant help in diagnosis and treatment of parathyroid cyst, but most of the patient could be treated successfully by surgical extirpation with an excellent chance for curability.
Biopsy, Fine-Needle
;
Diagnosis
;
Dyspnea
;
Humans
;
Male
;
Mediastinum
;
Needles
;
Parathyroid Hormone
;
Thyroid Gland
;
Ultrasonography
;
Voice
3.Emergency arteriography in extremity trauma
Yeo Sub LIM ; Hyun Sub JUNG ; See Sung CHOI ; Young Sun CHUNG ; Chahng Guhn KIM ; Jong Jin WON
Journal of the Korean Radiological Society 1986;22(5):767-771
The emergency arteriography have been performed in a total of 13 patiens with extermity trauma, including 9fractures, 3 blunting traumas, and 1 penetrating injury. over 17 months period. The indications were as follows:absent or diminishe pulse, swelling, sensory or motor deficit , and hypotension. Patients with an absent pulse,the most reliable indication of arterial injury, should have immediate arteriography. The superficial femoralartery was commonly injured especially with distal femoral shaft fracture. The most common arteriographic findingswas arterial occlusion.
Angiography
;
Emergencies
;
Extremities
;
Humans
;
Hypotension
4.Significance of postoperative serum level of carcinoembryonic antigen (CEA) and actual half life of CEA in colorectal cancer patients.
Yonsei Medical Journal 1997;38(1):1-7
The postoperative levels of carcinoembryonic antigen (CEA) and the actual half life (T1/2) of CEA were evaluated to ascertain their potency in predicting the recurrence of colorectal cancer after curative surgery in patients who had an abnormally high level of preoperative carcinoembryonic antigen (CEA, > or = 5 ng/ml). Ninety-four patients who underwent curative surgery were enrolled and 24 patients (25.5%) had recurrence during the follow-up period (median: 30 months, range: 2-69 months). T1/2 of CEA for all patients ranged from 1.2 days to 88.1 days, with a median of 4.4 days. T1/2 of CEA (mean +/- standard deviation) was 11.7 +/- 17.9 days in recurrent patients, whereas it was 6.2 +/- 4.9 days in patients without recurrence (p = 0.0224). The patients' age, gender, size of the tumor, location of the tumor, pre-, and postoperative CEA level, pathologic type of the tumor and Dukes stage had no significance in recurrence. The 1-year, 2-year, and 5-year disease-free survival rates were 95.1%, 81.1%, and 73.8% in patients with postoperative CEA levels less than 5 ng/ml (n = 62), respectively, and 71.4%, 64.8%, and 64.8% in patients with postoperative CEA levels higher than or equal to 5 ng/ml (n = 32), respectively (p = 0.04). Patients were divided into Group S (T1/2 of CEA < 4.4 days, n = 43) and Group L (T1/2 of CEA > or = 4.4 days, n = 51). The 1-year, 2-year, and 5-year disease-free survival rates were 95.3%, 85.1%, and 77.7% in Group S, respectively, and 80%, 67.5%, and 64.1% in Group L, respectively (p = 0.0261). In conclusion, the disease-free survival of colorectal cancer patients was prolonged in patients who had a short T1/2 of CEA or a low level of postoperative CEA. In high-risk colorectal cancer patients with an abnormally high level of preoperative CEA, recurrence may be predicted by checking an early postoperative CEA level and/or by a simple calculation of the actual half life of CEA.
Adolescence
;
Adult
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Aged
;
Aged, 80 and over
;
Carcinoembryonic Antigen/blood*
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Colorectal Neoplasms/surgery*
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Colorectal Neoplasms/blood*
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Female
;
Half-Life
;
Human
;
Male
;
Middle Age
;
Neoplasm Recurrence, Local
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Postoperative Period
;
Predictive Value of Tests
;
Retrospective Studies
5.Study on the role of sex steroid hormones playing in the control of rat ovarian tumor growth.
Jin Gook CHOI ; Kyu Sub LEE ; Sang NA ; Yong Jin NA ; Won Whe KIM
Korean Journal of Obstetrics and Gynecology 1993;36(7):2645-2651
No abstract available.
Animals
;
Gonadal Steroid Hormones*
;
Rats*
6.Exercise induced delayed bronchoconstriction in children with asthma.
Eun Jin CHOI ; Hyo Kung SHIN ; Un Ki YOON ; Ji Sub OH
Journal of the Korean Pediatric Society 1992;35(6):769-775
No abstract available.
Asthma*
;
Asthma, Exercise-Induced
;
Bronchoconstriction*
;
Child*
;
Humans
7.A Postoperative Thrombotic Thrombocytopenic Purpura in a Cardiac Surgery Patient: A Case Report.
The Korean Journal of Thoracic and Cardiovascular Surgery 2013;46(3):220-222
Although thrombotic thrombocytopenic purpura (TTP) is a rare disease, when it develops in a post-cardiac surgery patient, it may have a fatal outcome. Since the frequency of early-onset thrombocytopenia in post-cardiac surgery patients is high, platelet concentrates are commonly transfused during postoperative management. However, when TTP is the likely diagnosis, platelet transfusion is not recommended. We experienced a postoperative TTP in a cardiac surgery patient and discovered the importance of identifying the etiology of postoperative thrombocytopenia. Here, we report the case with a brief review of the literature.
Blood Platelets
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Fatal Outcome
;
Humans
;
Platelet Transfusion
;
Purpura, Thrombotic Thrombocytopenic
;
Rare Diseases
;
Thoracic Surgery
;
Thrombocytopenia
;
Thymine Nucleotides
8.A Postoperative Thrombotic Thrombocytopenic Purpura in a Cardiac Surgery Patient: A Case Report.
The Korean Journal of Thoracic and Cardiovascular Surgery 2013;46(3):220-222
Although thrombotic thrombocytopenic purpura (TTP) is a rare disease, when it develops in a post-cardiac surgery patient, it may have a fatal outcome. Since the frequency of early-onset thrombocytopenia in post-cardiac surgery patients is high, platelet concentrates are commonly transfused during postoperative management. However, when TTP is the likely diagnosis, platelet transfusion is not recommended. We experienced a postoperative TTP in a cardiac surgery patient and discovered the importance of identifying the etiology of postoperative thrombocytopenia. Here, we report the case with a brief review of the literature.
Blood Platelets
;
Fatal Outcome
;
Humans
;
Platelet Transfusion
;
Purpura, Thrombotic Thrombocytopenic
;
Rare Diseases
;
Thoracic Surgery
;
Thrombocytopenia
;
Thymine Nucleotides
9.Clinical Significance of the Actual Half-life of Serum Alpha-fetoprotein in Primary Hepatocellular Carcinoma.
Chul Woon CHUNG ; Jin Sub CHOI ; Byong Ro KIM
Journal of the Korean Surgical Society 2001;60(6):644-648
PURPOSE: We observed the actual half life of the alpha-fetoprotein (AFP) had clinical meaning in that it reflected the long term prognosis more individually at a certain level of preoperative alpha-fetoprotein. METHODS: From preoperative and postoperative measurements of alpha-fetoprotein in 96 hepatocellular carcinomas the actual half lives were calculated with the formula: AHL T1/2 (days) = -0.3x(T/log(C1/C0)), where T was the time interval between C1 and C0, in which C1 meant the level of AFP at postoperative 7 day, C0 the original AFP level. We investigated overall survival and disease free survival rate between delayed AHL group and non-delayed AHL group under various definitions of delay. RESULTS: The average actual half life of all cases was 5.1+/-13.6 days. One, three and five year overall survival rates of the group with actual half life less than 4 days were 82.1%, 66.7%, 61.1% respectively, whereas those of the group with actual half life more than 4 days showed 83.0%, 36.5%, 18.2% respectively. The significance of different survival rates was much higher, when only the patients with preoperative alpha-fetoprotein above 100 ng/ml were taken into account (n=53, P=0.0019). The disease free five year survival rates were also significantly different. CONCLUSION: We can predict the elevated postoperative survival rate in the patients with actual half life of alpha-fetoprotein less than 4 days. And this has also relevant clinical meaning in the prognostication of disease free survival, if the preoperative alpha-fetoprotein of patients has elevated up to over 100 ng/ml. The measurement of actual half life of postoperative hepatocellular carcinoma patientscan be a clinical useful parameter for the prognosis of long term survival.
alpha-Fetoproteins*
;
Carcinoma, Hepatocellular*
;
Disease-Free Survival
;
Half-Life*
;
Humans
;
Prognosis
;
Survival Rate
10.Two cases of postoperative chylothorax treated with parenteral octreotide and conservative therapy.
Korean Journal of Pediatrics 2007;50(3):298-301
Chylothorax is a rare complication following cardiac surgery for congenital heart diseases. Although conservative management is successful in the majority of cases, surgical intervention is required in a refractory one. Recently, subcutaneous or intravenous infusion of octreotide has been used as a safe treatment that helps avoiding surgical intervention. Herein, we report two cases of postoperative chylothorax treated with parenteral octreotide and conservative therapy.
Chylothorax*
;
Heart Diseases
;
Infusions, Intravenous
;
Octreotide*
;
Postoperative Complications
;
Thoracic Surgery