1.MR Findings of Intravertebral Vacuum Cleft: Report of Two Cases.
Sung Moon LEE ; Soo Jhi SUH ; Kyung Jin SUH
Journal of the Korean Radiological Society 1994;31(1):31-34
Intravertebral vacuum cleft in collapsed vertebra was considered as a typical finding of avascular necrosis. However, several authors reported some cases of intravertebral vacuum cleft in primary or secondary neoplasm, or in spondylitis emphasiging the differenhal diagnosis. MRI is known to be a useful diagnostic modality for diferentiation between benign and malignanct conditions causing vertebral collapse. We report MRI findings of two cases with intravertebral vacuum cleft diagnosed as posttraumatic collapse with avascular necrosis on radiological and clinical bases.
Diagnosis
;
Magnetic Resonance Imaging
;
Necrosis
;
Spine
;
Spondylitis
;
Vacuum*
2.No title available in English.
Woong Youn CHUNG ; Jin Hak SUH ; Cheong Soo PARK
Korean Journal of Endocrine Surgery 2001;1(2):279-280
No abstract available.
3.No title available in English.
Woong Youn CHUNG ; Jin Hak SUH ; Cheong Soo PARK
Korean Journal of Endocrine Surgery 2001;1(2):277-278
No abstract available.
4.Restoration of Hormone Dependency in Estrogen Receptor - Lipofected MDA-MB-231 Human Breast Cancer Cells.
Young Jin SUH ; Jae Hee CHANG ; Chung Soo CHUN
Journal of the Korean Cancer Association 1999;31(3):473-482
PURPOSE: The loss of estrogen and progesterone receptors appeats to be associated with a progression to less differentiated and hormone-independent tumors. The gain of hormone independency over time even in estrogen receptor-positive tumors has become another obstacle to endocrine therapy for breast cancer. We tried to regain the hormone dependency in estrogen receptor-negative breast cancer cells by lipofecting estmgen receptor cDNA. MATERIALS AND METHODS: The mutant human estrogen receptor cDNA (pSGS-HEO) was lipofected into estrogen receptor-negative human breast cancer cell line MDA-MB-231, in an attempt to restore their sensitivity to antiestrogen. Then the effects of 17p-estradiol and tamoxifen were studied by counting viable cell numbers after treating the lipofected cell line with either one or together. RESULTS: Culture medium cantaining phenol red, a weak estrogen, has growth advantages compared with culture medium without it. In both culture conditions, cell growth was most profoundly inhibited in 4 days after lipofection with mutant human estrogen receptor cDNA, which was overcome after that day. Tamoxifen, as an antiestrogen, showed a growth inhibitory effect slightly stronger tban combined conditions of tamoxifen and 17- estradiol compared to estrogen-treated group and to control, and the inhibitory effect was lasted 4 days. CONCLUSION: The temporary induction of estrogen receptor by lipofection with pSGS-HEO on estrogen receptor-negative human breast cancer cell line MDA-MB-231 showed negative growth control on these cells by tamoxifen, indicating that liposome-mediated estrogen receptor transfection may be used as a novel therapeutic strategy for hormane independent human breast cancers in the near future.
Breast Neoplasms*
;
Breast*
;
Cell Count
;
Cell Line
;
DNA, Complementary
;
Estradiol
;
Estrogen Receptor Modulators
;
Estrogens*
;
Genetic Therapy
;
Humans*
;
Phenolsulfonphthalein
;
Receptors, Progesterone
;
Tamoxifen
;
Transfection
5.Rheumatoid Arthritis: MR Imaging of the Wrist: A Preliminary Report.
Jae Hyun CHO ; Soo Kon LEE ; Jin Suck SUH
Journal of the Korean Radiological Society 1994;31(6):1157-1161
PURPOSE: To evaluate the optimal pulse sequences in the detection of erosions and for the discrimination of theeffusion from pannus. MATERIALS AND METHODS: MR studies were performed in thirteen patients with clinical diagnosis of rheumatoid arthritis. We used a 1.5T MR unit with single or dual 3 inch coil. We compared coronal images at the same location, obtained with pulse sequences of T2, T2 with fat saturation, and postcontrast T1 with fat suppression. Erosions were assessed by comparing the count of the numbers of erosions depending on each imaging method. A four point scoring systems was used for the comparison of conspicuitof lesion. RESULTS: T2WI with fat suppression and postcontreat T1WI with fat suppresison were better than conventional T2WI in the detection of erosions. The pannus had a heterogeneous signal on T2WI, some of which were enhanced after the intravenous injection of MR contrast a gents. CONCLUSION: We suggest that the fat suppression TIWI with enhacnement or the fat suppression T2WI were better than conventional T2WI for detecting both bone erosion and pannus. The postcontrast MR imaging may often be helpul in distinguishing pannus from the effusion.
Arthritis, Rheumatoid*
;
Diagnosis
;
Discrimination (Psychology)
;
Humans
;
Injections, Intravenous
;
Magnetic Resonance Imaging*
;
Wrist*
6.The cause of recurrent anal fistula.
Soo Lo KIM ; Dong Youb SUH ; Jin Kook KANG
Journal of the Korean Surgical Society 1993;45(5):862-869
No abstract available.
Rectal Fistula*
7.A Case of Lichen Nitidus.
Jung Kwoun SUH ; Jin Taik KIM ; Soo Gil SUHL
Korean Journal of Dermatology 1969;7(1):53-55
A case of lichen nitidus in 23 years old male was described. This is the first case report in Korea. The clinical and histopathological study revealed characteristic features of the disease. Authors reviewed therapeutic experience and reports of the literaturea.
Humans
;
Korea
;
Lichen Nitidus*
;
Lichens*
;
Male
;
Young Adult
8.Comparison of CT findings with upper GI series and surgical findings
Jin Kyo HONG ; Soo Jhi SUH ; Soon Yong KIM
Journal of the Korean Radiological Society 1981;17(2):287-292
The authors made comparative studies of CT findings with upper GI series and surgical findings in 20 cases of histologically proven gastric cancers. The identification of thickening of gastric wall and local and remotemetastasis by CT was thought to be great value in treatment planning and prediction of prognosis of the patients. The results were as follows; 1. Of 20 cases, 19 cases demonstrated thickening of gastric wall. Among 3 cases suggested as early cancer on upper GI series, 2 cases demonstrated thickened gastric wall on CT and it was provedto be advanced cancer at surgery. 2. Out of 8 cases showed no definite metastasis on CT, 4 cases had malignant in filtration histologically in the regional lymph nodes. But they were less than 1.5 cm in diameter. 3. The frequency order of remote metastasis found by CT was pancreas, liver, left adrenal gland and lung in organs and retroperitoneal, regional nodes in lymph nodes.
Adrenal Glands
;
Filtration
;
Humans
;
Liver
;
Lung
;
Lymph Nodes
;
Neoplasm Metastasis
;
Pancreas
;
Prognosis
;
Stomach Neoplasms
9.Appraisal of the Results of Throat Swab Culture Obtained from Pediatric Outpatient Clinic.
Sung Ho CHA ; Byoung Soo CHO ; Hwan Jo SUH ; Jin Tae SUH ; Seon Ju KIM
Journal of the Korean Pediatric Society 1995;38(7):895-900
No abstract available.
Ambulatory Care Facilities*
;
Humans
;
Outpatients*
;
Pharynx*
10.MRI of cervical carcinoma: before and after chemotherapy.
Jung Sik KIM ; Soo Jhi SUH ; Tae Jin CHOI ; Tae Sung LEE ; Young Wook SUH
Journal of the Korean Radiological Society 1992;28(6):927-934
To evaluate usefulness of MR in assessment of tumor response to the chemotheraphy, we prospectively studied cases of cervical carcinoma with more then 2.5cm in diameter or stage IIb or more. Three courses of chemotherapy were performed with cisplatin and 5 F-U. MR images were obtained both before and after chemotherapy. Nine of 13 patients were undertaken radical hysterectomy after chemotherapy and MR examination. MR volumetry, stage and depth of stromal invasion were compared before and after chemotherapy. And in 9 patients who underwent radical hysterectomy, comparison of pathologic and MR imaging findings were also done. @ES The results were following. @EN 1) All tumors dectrased in volume (m=80.5%). 2) Five tumors (38.5%) reduced in stage, IB→CIS(1); IIA→CIS(1), IIA→IB(2), IIB→IB(1). 3) Depth of stromal invasion in MRI correlated well with that of histo-pathologic specimen in 7 of the 9 patients. Conclusively MR imaging is useful in assessement of tumor response to chemotherapy.
Cisplatin
;
Drug Therapy*
;
Humans
;
Hysterectomy
;
Magnetic Resonance Imaging*
;
Prospective Studies