No abstract available.

122 cases of the genitourinary tract tumors admitted to the Department of Urology, National Medical Center, during the period, Aug. 1968 to July 1975 and the followings are the results. 1. 122-cases(12.8%) were tumor patient among 954 (male 702, female 252) Total admitted patients during 7 years. 2. Age distribution was from 5 months to 83 years showing the highest incidence in the 7th decade (30.3%) and cases over 41 years of age were 99(81.1%) 3. Sex ratio of male and female was 5.4:1(103:19) 4. In 122 cases, 42 cases{34.4%) were benign, 77 cases(63. 1%) were malignant and remainders were uncertain pathologically. 5. Among 122 cases, 57 cases(46.7%) were vesical, 35 cases(28.7%) prostatic, 19 cases(15.6%) renal, 5 cases(4.1%) penile. 3 cases(2.5%) testicular and 3 cases(2.5%) were urethral tumors. 6. Operations were performed in 114 patients (93.5%).
Age Distribution ; Female ; Humans ; Incidence ; Male ; Sex Ratio ; Urology

A 56 year-old female presented with dysphagia 8 weeks ago and newly developed dysphonia 2 weeks ago. The radiology study and swallowing difficulty evaluation study revealed the esophagus and the posterior wall of the laryngopharynx to be severely compressed by the mass of the anterior 4th and 5th vertebral body of cervical spine. En bloc excisional biopsy of the bony mass was performed, which completely resolved the clinical symptoms. We report a rare case of osteochondroma occurring at the anterior portion of cervical spine leading to dysphasia and dysphonia with a review of relevant literature.
Aphasia ; Biopsy ; Deglutition ; Deglutition Disorders ; Dysphonia ; Esophagus ; Female ; Humans ; Hypopharynx ; Osteochondroma ; Spine

This study was performed to find out the relationship between DNA pattern by flow cytometry and the prognosis of cervical squamous cell carcinoma, The subjects were 71 patients who were admitted to Catholic University Medical College Kangnam St. Marys Hospital from September 1983 to May 1989 under the diagnosis of cervical squamous cell carainoma. Samples were obtained from the subjects before chemotherapy or radiation therapy, and a through follow up stduy was carried out an the subjects. The authors obserued the relations between flow cytometric DNA pattern and clinical stage, age of patients, histopathological findings and tumor markers, with the following results. 1. The S-phase of the cell cycle increased significantly in Stages I, ll and III-IV compared to that of Stage O.However, there was no difference between Stages in G0/G1 phase and G2/M phase. 2. The incidence of aneuploid tumor increased significantly according to stage with the rates of increase reaching 22, 22%, 31.57%, 44.44% and 68.75% respectively in Stages 0, I, II, and Ill-lV. 3. The incidence of aneuploid tumor increased significantly depending on the age of patients with the rates standing at 21.42%, 31.58%, 40.90% and 68.75% respectively in the groups of below 40, 41-50, 51-60, and 61 years and over. 4. As for the relation between histopathological findings and the incidenee of aneuploid tumor, no difference was found according to the degree of differentiation, but there were significant differences between the keratinization group(23.07%) and the non keratinization group(51.11%).
Aneuploidy ; Carcinoma, Squamous Cell* ; Cell Cycle ; Cervix Uteri* ; Diagnosis ; DNA* ; Drug Therapy ; Female ; Flow Cytometry ; Follow-Up Studies ; Humans ; Incidence ; Prognosis* ; Biomarkers, Tumor

The prevalence for the development of dementia is about 10% and 20% in people over the age of 65 and 80, respectively. Underlying causes for its development are various. With the progress of modem medicine, the mean survival age is dramatically increased and for the consequence, greater number of people suffer from dementia. According to the postmortem studies, 70% of the dementia patients were of the Alzheimer's type. In recent times, active research on the relationship between the Alzheimer's disease and the neurochemical changes is being conducted and much progress has been made. In addition to the consistant deficiency of cholinergic system, abnormal ities in noradrenergic and GABAergic systems and reductions of somatostatin have been reported. In the same areas of brain of patients who suffered from Alxheimer's disease where these changes of neurotransmitters were found, there were massive accumulation of aluminium. Therefore, this review discusses the specific changes of various neurotransmitters in the brain and the potential therapeutic agents in Alzheimer's disease.
Alzheimer Disease* ; Brain ; Dementia ; Humans ; Modems ; Neurotransmitter Agents ; Prevalence ; Somatostatin

No abstract available.
Gonadotropin-Releasing Hormone* ; Humans

This authors reviewed the radiographs of 20,057 patients with spinl radiculomyelopathy from April 1983 August 1990. The incidence and distribtion of the ossification of the spinal ligaments were analized as following. 1) The overall incidence of spinal ligaments ossification was 3.6% among 20,057 patients. 2) The most frequently occurs at lumbar area(67.1%), and then cervical(27.5%) thoracic(0.4%) area as in orders. 3) The OPLL was most common type(2.19%) of these spinal ligaments ossification, and then OALL(0.7%), OLF(0.24%) as in orders. 4) OPLL (1) OPLL was most frequent at lumbar area(58.6%) and then cervical(37.0%), thoracic(0.4%) area as in orders. (2) The cervical OPLL was commonly found at C5 & C6 area and morphologically, the multiple segmented type was most common then continuous type, mixed type and single segmented type in orders. (3) The multiple segmented type was more frequently found at upper cervical area, but the continuous type was more frequent at lower cervical area. 5) OALL (1) OALL was most frequent at lumbar area(86.0%) but thoracic(1.4%) and cervecal area(5.3%) were relatively low in frequency. (2) Of the lumbar OALL, the L4/5 area was most frequent site(37.8%) but the L3/4(25.3%) and L5/S1 area(24.5%) also had relatively high occurance rate. 6) OLF (1) OLF was most frequent at lumbar area(92.7%), but the incidence of OLF was relativerly rare at cervical(2.1%) and thoracic area(5.2%). (2) Of the lumbar OLF, the L4/5 area was most common site(33.1), but L5/S1 area had also high occurance rate(27.2%).
Humans ; Incidence ; Ligaments*

This study was done on 171 volunteers in order to investigate the present status of cutaneous normal flora of Candida species and the distribution of Candida species on the normal human skin in dermatologic clinic of Korea University Hospital from January, ]984 to December, 1984. Among the 171 volunteers, 115 strains of Candida species were identified by culture on the Sabouraud's dextrose agar media, germ tube test, sugar assimilation test, sugar fermentaion test and culture on corn meal with Tween 80 media, The results were summarized as follows: 1. The incidence of cutaneous normal flora of Candida species was 13, 5,5 (115 species among 855 sites) 2. Candida species were distributed in oral cavity(45 species), 4th interdigital toe web(39 species), groin(12 species), axilla(11 species) and 4th interdigital finger web(8 species) in order of frequency. 3, Of ll5 species, 45 species were cultured in summer, 27 species in autumn, 18 species in winter and 14 species in spring. 4 Of 115 Candida species, C. albicans(88 species), C. parapsilosis(12 species), C, tropicalis(8 species), C. guilliermondii(3 species) and C. stellatoidea(2 species) were identified. Two species could not be identified.
Agar ; Candida* ; Fingers ; Glucose ; Humans* ; Incidence ; Korea ; Meals ; Polysorbates ; Skin* ; Toes ; Volunteers ; Zea mays

No abstract available.
Oncogenes*

We report a case of a photosensitivity reaction in a 76-year-old inale induced by chlorpropamide ingestion. The patient had erythematous scaly patches on the sur. -exposed areas, A phototest revealed the decreased minimal erythemal dose(MED) to UVA(5J/cm). A photopatch test and photo-scartch test with 1% chlorpropamide ointment and 0.1% chlorpropamic!e .olution were all negative. An oral provocation test was performed, which showed a positive result with marked decrease of MED to UVA (5J/cm). After the cessation of chlorpropamide, his skin lesions were improved markedly with complete loss of photosensitivity. Macular hypopigmentations (leukcme.anoderma) appeared on the previous erythematous patchy ereas, but disappeared during the follow-up period.
Aged ; Chlorpropamide ; Eating ; Follow-Up Studies ; Humans ; Skin