Crohn's disease is a rare inflammatory bowel disease in Korea which requires a differential diagnosis with intestinal tuberculosis. In the early stages of Crohn's diseaae, the combiation of bowel wall edema and spasm produces intermittent obstructive manifestations, so the usual subjective symptoms were appeared long standing diarrhea, low grade fever and abdominal pain and distension. We recently experienced a case of Crohn's colitis with repeated bowel obstruction in female adult who underwent surgical resection.
Abdominal Pain ; Adult ; Colitis ; Crohn Disease* ; Diagnosis, Differential ; Diarrhea ; Edema ; Female ; Fever ; Humans ; Inflammatory Bowel Diseases ; Korea ; Spasm ; Tuberculosis

Crohn's disease is a rare inflammatory bowel disease in Korea which requires a differential diagnosis with intestinal tuberculosis. In the early stages of Crohn's diseaae, the combiation of bowel wall edema and spasm produces intermittent obstructive manifestations, so the usual subjective symptoms were appeared long standing diarrhea, low grade fever and abdominal pain and distension. We recently experienced a case of Crohn's colitis with repeated bowel obstruction in female adult who underwent surgical resection.
Abdominal Pain ; Adult ; Colitis ; Crohn Disease* ; Diagnosis, Differential ; Diarrhea ; Edema ; Female ; Fever ; Humans ; Inflammatory Bowel Diseases ; Korea ; Spasm ; Tuberculosis

No abstract available.
Sturge-Weber Syndrome*

No abstract available.

No abstract available.
Ectromelia*

No abstract available
Dermatitis, Atopic* ; Eczema* ; Humans ; Nipples*

BACKGOUND: Narrow-band ultraviolet B (NBUVB) phototherapy has appeared to be effective in clearing psoriatic lesions. Calcipotriol has been combined with a number of the systemic antipsoriatic treatments, improving efficacy or reducing the systemic treatment required. OBJECTIVE: We performed calcipotriol-NBUVB combination therapy to evaluate the clinical efficacy and the safety in Korean psoriasis patients. METHOD: In the psoriasis clinic at Seoul National University Hospital, 69 psoriasis patients were treated with calcipotriol-NBUVB. Phototherapy was given once daily, three times a week, and the dose was gradually increased. Calcipotriol ointment was applied twice a day. The PASI score was used to evaluate the effects of the treatment and the patients were classified according to clearance, improvement, or failure. RESULTS: The therapeutic results showed 53.6% for clearance, 31.9% for improvement and 14.5% for failure. The total number, duration, final and cumulative doses to achieve grade IV were 16.1, 41.8days, 1487.3mJ/cm2, and 15234.5mJ/cm(2) respectively. Of 69 patients, 44 patients experienced variable adverse effects, but there was no significant adverse effect to discontinue the therapy. CONCLUSION: Our results demonstrated that using calcipotriol ointment with NBUVB phototherapy is an effective therapeutic method for psoriatic patients.
Humans ; Phototherapy* ; Psoriasis ; Seoul

In full-thickness defects of the nasal alar rim, to achieve projection and maintain airway patency, cartilage graft is frequently needed. However, cartilage graft presents a challenge in considerations such as appropriate donor site, skeletal shape and size, and healing of the donor area. To avoid these demerits, we tried primary closure of alar rim defects by also making the contralateral normal ala smaller. We treated two patients who had a full-thickness nasal alar defect after tumor excision. Cartilage graft was considered for the reconstruction. However, their alar rims were overly curved and their nostril openings were large. To utilize their nasal shape, we did primary closure of the defect rather than cartilage graft, and then downsized the contralateral nasal ala by means of wedge resection to make the alae symmetric. Both patients were satisfied with their aesthetic results, which showed a smaller nostril and nearly straight alar rims. Moreover, functionally, there was no discomfort during breathing in both patients. We propose our idea as one of the reconstruction options for nasal alar defects. It is a simple and easy-to-perform procedure, in addition to enhancing the nasal contour. This method would be useful for patients with a large nostril and an overly curved alar rim.
Cartilage ; Humans ; Nose Deformities, Acquired ; Reconstructive Surgical Procedures ; Respiration ; Tissue Donors ; Transplants

BACKGROUND: Facial involvement of psoriasis requires a different approach than that used for typical plaque psoriasis on other skin areas. Calcitriol ointment may improve lesions on the face without atrophy or other local side effects associated with the use of topical corticosteroids. OBJECTIVE: Our purpose was to determine the efficacy and tolerability of calcitriol 3 microgram/g ointment for the treatment of facial psoriasis. METHODS: In the psoriasis clinic of Seoul National University Hospital, a total of 53 patients were treated with calcitriol 3 microgram/g for 8 weeks. Efficacy was evaluated by an investigator's assessment of the area and a severity index score of facial psoriasis at the 2nd, 4th, and 8th week. Global assessment was also determined at the 8th week. RESULTS: A total of 10 patients discontinued prematurely from the study, due to disappearing during follow-up treatment (n=9) and combined use of topical corticosteroids (n=1). The remaining patients showed the following response to treatment; excellent (n=10), good (n=14), fair (n=11), and poor (n=8). After 8 weeks of treatment with calcitriol ointment, clinical improvement was achieved in 81.4% of the patients. Among them, 55.8% showed excellent (23.3%) or good effect (32.5%) with calcitriol ointment. Five patients (11.6%) showed a local adverse reaction such as erythema, exfoliation, or an itching sensation, and 2 patients discontinued treatment due to adverse reactions. However, no patient showed telangiectasia, skin atrophy, or systemic side effects. CONCLUSION: Our results suggest that calcitriol ointment is an effective and tolerable agent for treatment of psoriasis on the face.
Adrenal Cortex Hormones ; Atrophy ; Calcitriol* ; Erythema ; Follow-Up Studies ; Humans ; Pruritus ; Psoriasis* ; Sensation ; Seoul ; Skin ; Telangiectasis