No abstract available.
Humans* ; Prostate* ; Prostatic Neoplasms*

No abstract available.
Humans* ; Prostate* ; Prostatic Neoplasms*

No abstract available.

Cardiac arrest associated with hyperkalemia during red blood cell transfusion is a rare but fatal complication. Herein, we report a case of transfusion-associated cardiac arrest following the initiation of extracorporeal membrane oxygenation support in a 9-month old infant. Her serum potassium level was increased to 9.0 mEq/L, soon after the newly primed circuit with pre-stored red blood cell (RBC) was started and followed by sudden cardiac arrest. Eventually, circulation was restored and the potassium level decreased to 5.1 mEq/L after 5 min. Extracorporeal membrane oxygenation (ECMO) priming is a relatively massive transfusion into a pediatric patient. Thus, to prevent cardiac arrest during blood-primed ECMO in neonates and infants, freshly irradiated and washed RBCs should be used when priming the ECMO circuit, to minimize the potassium concentration. Also, physicians should be aware of all possible complications associated with transfusions during ECMO.
Blood Transfusion ; Death, Sudden, Cardiac ; Erythrocyte Transfusion ; Erythrocytes ; Extracorporeal Membrane Oxygenation* ; Heart Arrest* ; Humans ; Hyperkalemia* ; Infant* ; Infant, Newborn ; Potassium

From 1980 to 1989, 144 patients underwent radical nephrectomy for renal cell carcinoma. Survival was analyzed in terms of pathologic stage and histologic grade. Data revealed that M category was the most important prognostic factor followed by, in order of importance, T category, N category, and grade. But grade as prognostic factor in renal cell carcinoma needs additional investigation. Stage pT1 and pT2 showed similar survival rate. The separation of pT1 and pT2 according to size of the primary tumor may not be a meaningful prognostic variable. Because vascular invasion may occur with tumors of various size, separating components into a description of the tumor (T), nodes (N), metastases (M) and renal vein involvements (V) makes good sense. The prognostic value of lymphadenectomy is limited by the fact that the tumor metastasizes through the blood stream and the lymphatic system with equal frequency.
Carcinoma, Renal Cell* ; Humans ; Lymph Node Excision ; Lymphatic System ; Neoplasm Metastasis ; Nephrectomy ; Renal Veins ; Rivers ; Survival Rate

From 1981 to 1987, 91 patients underwent radical nephrectomy for renal cell carcinoma. The regional lymph nodes were resected in 42 patients with disease localized to the kidney. The following results were obtained. 1. 5 year survival rates for patients with stage TlNOMO, T2NOMO and T3aNOMO were 100, 81.8 and 66.4 %, respectively, and for patients with stage T3bNOMO or regional lymph node involvement was 0 %. 2. The incidence of regional lymph node involvement in patients with stage T1, T2 and T3a was 0, 13.0 and 31.8%, respectively. 3. The extended lymphadenectomy for renal cell carcinoma was not proved to be more effective than radical nephrectomy only. 4. Staging was correct with computerized tomography in 71.0% of the lesions but stage T1 was determined correctly by computerized tomography in 100 % of patients. When the efficiency of computerized tomography and the possibility of regional lymph node involvement is considered, and extended lymphadenectomy is not a suggested addition to radical nephrectomy in patients with stage T1 renal cell carcinoma. In the future radioimmunoassay techniques or magnetic resonance imaging techniques may provide additional information in the evaluation of metastatic disease.
Carcinoma, Renal Cell* ; Humans ; Incidence ; Kidney ; Lymph Node Excision ; Lymph Nodes* ; Magnetic Resonance Imaging ; Nephrectomy ; Radioimmunoassay ; Survival Rate

No abstract available.
Ambulatory Care Facilities* ; Humans ; Outpatients* ; Pharynx*

BACKGROUND: Temporary interruption of blood flow to the liver is often unavoidable during operations for extensive injury of the liver or for major liver resection. Following ischemia- reperfusion, transient dysfunction of the liver occurs. It has been suggested that reactive oxygen metabolites play an important role in microvascular reperfusion injury. Superoxide dismutase (SOD) and dimethylthiourea (DMTU) are known to be antioxidants that scavenge oxygen free radicals to reduce microvascular reperfusion injury. This experiment studied the effect of SOD and DMTU on warm ischemia-reperfusion injury to the liver and compared inflow occlusion and hepatic vascular exclusion (HVE) after 20 minutes of ischemia. METHODS: One hundred fourteen healthy male Sprague-Dawley rats weighing around 250 g were used. The rats were divided into control (n=18) and experimental groups (n=96). The control groups included sham, SOD, and DMTU control groups. The experimental groups included inflow occlusion, SOD- pretreated inflow occlusion, DMTU-pretreated inflow occlusion, and inflow and outflow occlusion (HVE) groups. These 4 experimental groups had 24 rats each. The rats were sacrificed immediately, and at 24 hours, 48 hours, and 72 hours after reperfusion, and specimens were obtained from left anterior lobe of the liver. The specimens were prepared using routine methods for electron-microscope observations. RESULTS: The ultrastructures of the hepatocytes in all the experimental groups were similar to those of the normal control rats after just 20 minutes of ischemia. In the inflow occlusion group, dilatation and sacculation of the cisternae of the endoplasmic reticulum and mitochondria with many electron dense granules were observed in the hepatocytes after 24 hours of reperfusion. In the course of reperfusion, damage progressed until 72 hours after reperfusion. The HVE group showed more serious changes than the inflow occlusion group. The SOD- and the DMTU-treated groups showed clear attenuation of liver damage after 48 and 72 hours of reperfusion.CONCLUSION: The ultrastructural changes of hepatocytes after 20 minutes of ischemia became more prominent by prolonging the reperfusion time. The changes after hepatic inflow occlusion were less prominent than those after HVE. DMTU and SOD attenuated the injury to hepatocytes after warm ischemia-reperfusion.
Animals ; Antioxidants ; Dilatation ; Endoplasmic Reticulum ; Free Radicals ; Hepatocytes* ; Humans ; Ischemia ; Liver ; Male ; Mitochondria ; Oxygen ; Rats* ; Rats, Sprague-Dawley ; Reperfusion ; Reperfusion Injury* ; Superoxide Dismutase* ; Superoxides*

No abstract available.
Methemoglobinemia*

No abstract available.
Constriction, Pathologic*