2.Comparison of outcome after controlled ovarian hyperstimulation with GnRH agonist(Lupron) and gonadotropins between previous poor responders and premature LH surge responders.
Seok Hyun KIM ; Shin Yong MOON ; Jin Yong LEE ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(4):571-582
No abstract available.
Gonadotropin-Releasing Hormone*
;
Gonadotropins*
3.Radial motor nerve conduction study using surface electrode in normal adults.
Sae Yoon KANG ; Young Jin KO ; Eun Seok CHOI ; Chan Seok OH
Journal of the Korean Academy of Rehabilitation Medicine 1992;16(4):385-389
No abstract available.
Adult*
;
Electrodes*
;
Humans
;
Neural Conduction*
4.Improvement of titration methods for porcine rotavirus, its serum neutralizing antibody and of virus isolation from feces.
Hyock Jin KWON ; Seok Min YOON ; Rung Kong HA ; Sung Soo CHO ; Ji Byung YOON
Journal of the Korean Society of Virology 1991;21(2):113-117
No abstract available.
Antibodies, Neutralizing*
;
Feces*
;
Rotavirus*
5.A case of combined pregnancy following IVF-ET.
Man Chul PARK ; Chi Seok AHN ; Seok Hyun KIM ; Shin Yong MOON ; Jin Yong LEE ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(10):1457-1462
No abstract available.
Pregnancy*
6.Comparison of superovulation characteristics and in vitro fertilization outcomes between short and long protocols using gonadotropinreleasing hormone agonist.
Shin Yong MOON ; Jin CHOE ; Yong Sang SONG ; Seok Hyun KIM ; Jung Gu KIM ; Jin Yong LEE ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(8):1125-1133
No abstract available.
Fertilization in Vitro*
;
Superovulation*
7.Effects of selenium on the survival and invasion of trophoblasts.
Jee Yoon NA ; Jin SEOK ; Sohae PARK ; Jung Seok KIM ; Gi Jin KIM
Clinical and Experimental Reproductive Medicine 2018;45(1):10-16
OBJECTIVE: Placental oxidative stress is known to be a factor that contributes to pregnancy failure. The aim of this study was to determine whether selenium could induce antioxidant gene expression and regulate invasive activity and mitochondrial activity in trophoblasts, which are a major cell type of the placenta. METHODS: To understand the effects of selenium on trophoblast cells exposed to hypoxia, the viability and invasive activity of trophoblasts were analyzed. The expression of antioxidant enzymes was assessed by reverse-transcription polymerase chain reaction. In addition, the effects of selenium treatment on mitochondrial activity were evaluated in terms of adenosine triphosphate production, mitochondrial membrane potential, and reactive oxygen species levels. RESULTS: Selenium showed positive effects on the viability and migration activity of trophoblast cells when exposed to hypoxia. Interestingly, the increased heme oxygenase 1 expression under hypoxic conditions was decreased by selenium treatment, whereas superoxide dismutase expression was increased in trophoblast cells by selenium treatment for 72 hours, regardless of hypoxia. Selenium-treated trophoblast cells showed increased mitochondrial membrane potential and decreased reactive oxygen species levels under hypoxic conditions for 72 hours. CONCLUSION: These results will be used as basic data for understanding the mechanism of how trophoblast cells respond to oxidative stress and how selenium promotes the upregulation of related genes and improves the survival rate and invasive ability of trophoblasts through regulating mitochondrial activity. These results suggest that selenium may be used in reproductive medicine for purposes including infertility treatment.
Adenosine Triphosphate
;
Anoxia
;
Antioxidants
;
Gene Expression
;
Heme Oxygenase-1
;
Infertility
;
Membrane Potential, Mitochondrial
;
Mitochondria
;
Oxidative Stress
;
Placenta
;
Polymerase Chain Reaction
;
Pregnancy
;
Reactive Oxygen Species
;
Reproductive Medicine
;
Selenium*
;
Superoxide Dismutase
;
Survival Rate
;
Trophoblasts*
;
Up-Regulation
8.Antiendometrial antibodies in the serum of patients with endometriosis.
Jung Gu KIM ; Chi Seok AHN ; Byung Gu YOON ; Kyung Hee LEE ; Seok Hyun KIM ; Shin Yong MOON ; Jin Yong LEE ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1992;35(1):103-108
No abstract available.
Antibodies*
;
Endometriosis*
;
Female
;
Humans
9.Clinical significance of serum progesterone level on day of human chorionic gonadotropin injection following gonadotropin releasing hormone agonist combined superovulation.
Yong Sang SONG ; In Hwa ROH ; Seok Hyun KIM ; Jung Gu KIM ; Shin Yong MOON ; Jin Yong LEE ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(10):1416-1424
No abstract available.
Chorionic Gonadotropin*
;
Gonadotropin-Releasing Hormone*
;
Gonadotropins*
;
Humans*
;
Progesterone*
;
Superovulation*
10.Studies on oocyte donation in IVF program.
Seok Hyun KIM ; Chang Jae SHIN ; Jung Gu KIM ; Shin Yong MOON ; Jin Yong LEE ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(4):559-570
No abstract available.
Oocyte Donation*
;
Oocytes*