1.Effects of Power Output and Energy Density on the Histologic Change of Guinea pig Skin Following Copper Vapor Laser Irradiation.
Woo Seok KOH ; Jin Ho CHUNG ; Jai Il YOUN
Korean Journal of Dermatology 1994;32(4):591-598
BACKGROUND: Recentliy copper vapor laser(CVL) has been applied with encouraging results in the treatment of port wine stain. The CVL emits yellow light(578nm) in a sequence of about 10,000 to 15,000 pulses/second(10-15kHz) with a pulse duration of 15-50 cases. One of the basic methods of evaluationg the effects of laser lights is to study histologic changes after laser irradiation. OBJECTIVE: The effects of power output and energy density on the histologic change of guinea pig skin following CVL irradiation was evaluted to suggest a way of deciding parameters of CVL to achieve the best clinical results. METHODS: After setting the power output for one of 0.8W, 1.6W and 2.4W, the laser was irradiated with an energy density of 10, 12, 14, 16, 18, 20J/cm. A biopsy was done 15 minutes after irradiation and the biopsy specimens was stained with H&E and NBTC histocberr ical method. RESULTS: 1. At the power of 0.8W, specimens irradiated with an energy density above 14J/cm showed diffuse nonspecific coagulation necrosis of the epidermis and upper dermis. 2. At the power of 1.6W, specimens irradiated with energy density of 14, 16J/cm showed coagulation necrosis of dermal vessel and perivascular collagen. With energe density of 18, 20J/cm, diffuse nonspecific coagulat,ion necrosis of epidermis and upper dermis were observed. 3. At the power of 2.4W, specimens irradiated with an anergy density of 12, 14, 16, 18J/cm showed coagulation necrosis of the dermal vessel and perivascular collagen. With an energy density of 20J/cm, diffuse nonspecific coagulation necrosis of the epidermis and upper dermis was observed. CONCLUSIONS : With the above results it was found that t,he higher power output of CVL enlarged the range of energy density confining thermal damage to the dermal v-ssels and perivascular collagen. Additionally the higher power raised the upper limit of energy density with which t,he epidermis was viable.
Animals
;
Biopsy
;
Collagen
;
Copper*
;
Dermis
;
Epidermis
;
Guinea Pigs*
;
Guinea*
;
Herpes Zoster
;
Humans
;
Inpatients
;
Lasers, Gas*
;
Necrosis
;
Port-Wine Stain
;
Skin*
2.Effects of Power Output and Energy Density on the Histologic Change of Guinea pig Skin Following Copper Vapor Laser Irradiation.
Woo Seok KOH ; Jin Ho CHUNG ; Jai Il YOUN
Korean Journal of Dermatology 1994;32(4):591-598
BACKGROUND: Recentliy copper vapor laser(CVL) has been applied with encouraging results in the treatment of port wine stain. The CVL emits yellow light(578nm) in a sequence of about 10,000 to 15,000 pulses/second(10-15kHz) with a pulse duration of 15-50 cases. One of the basic methods of evaluationg the effects of laser lights is to study histologic changes after laser irradiation. OBJECTIVE: The effects of power output and energy density on the histologic change of guinea pig skin following CVL irradiation was evaluted to suggest a way of deciding parameters of CVL to achieve the best clinical results. METHODS: After setting the power output for one of 0.8W, 1.6W and 2.4W, the laser was irradiated with an energy density of 10, 12, 14, 16, 18, 20J/cm. A biopsy was done 15 minutes after irradiation and the biopsy specimens was stained with H&E and NBTC histocberr ical method. RESULTS: 1. At the power of 0.8W, specimens irradiated with an energy density above 14J/cm showed diffuse nonspecific coagulation necrosis of the epidermis and upper dermis. 2. At the power of 1.6W, specimens irradiated with energy density of 14, 16J/cm showed coagulation necrosis of dermal vessel and perivascular collagen. With energe density of 18, 20J/cm, diffuse nonspecific coagulat,ion necrosis of epidermis and upper dermis were observed. 3. At the power of 2.4W, specimens irradiated with an anergy density of 12, 14, 16, 18J/cm showed coagulation necrosis of the dermal vessel and perivascular collagen. With an energy density of 20J/cm, diffuse nonspecific coagulation necrosis of the epidermis and upper dermis was observed. CONCLUSIONS : With the above results it was found that t,he higher power output of CVL enlarged the range of energy density confining thermal damage to the dermal v-ssels and perivascular collagen. Additionally the higher power raised the upper limit of energy density with which t,he epidermis was viable.
Animals
;
Biopsy
;
Collagen
;
Copper*
;
Dermis
;
Epidermis
;
Guinea Pigs*
;
Guinea*
;
Herpes Zoster
;
Humans
;
Inpatients
;
Lasers, Gas*
;
Necrosis
;
Port-Wine Stain
;
Skin*
3.The treatment of neglected patellar fracture: report of 2 cases.
Jin Young KIM ; In Ju LEE ; Nam Yong CHOI ; Seok Whan SONG ; Hae Seok KOH
The Journal of the Korean Orthopaedic Association 1991;26(1):298-303
No abstract available.
4.Allopurinol Induced Abnormalities of Liver Function Test in Gout Patients.
Gi Hyeon SEO ; Hong Joon AHN ; Hoon Suk CHA ; Jin Seok KIM ; Kwang Cheol KOH ; Eun Mi KOH
The Journal of the Korean Rheumatism Association 1999;6(1):62-68
Liver function tests before treatment showed abnormalities of liver function tests during treatment, while 15(68. 2%) of 22 patients who had abnormal liver function tests before treatment showed abnormalities during treatment. In 12 of the 25 patients who showed abnormalities of liver function tests during treatment with allopurinol, allopurinol was stopped and all patients showed improvement of liver function tests. In remaining 13 patients, 10 patients were improved and other 2 patients showed only mild abnormalities of liver function tests despite of continuing allopurinol and 1 patient was lost during follow-up. CONCLUSION: Abnormalities of liver function tests were common during treatment with allopurinol. Most patiensts who had mild abnormalities of liver functions tests during treatment with allopurinol were improved regardless of continuing allopurinol.
Allopurinol*
;
Follow-Up Studies
;
Gout*
;
Humans
;
Liver Function Tests*
;
Liver*
5.A case of Ellis-van Creveld syndrome.
Hee Seok KOH ; Sha Young CHOI ; Sung Jin HA ; Oh Kyung LEE
Journal of the Korean Pediatric Society 1992;35(3):411-416
No abstract available.
Ellis-Van Creveld Syndrome*
6.Serum Ferritin as an Indicator of Disease Activity in Adult Onset Still's Disease.
Gi Hyeon SEO ; Hong Joon AHN ; Hoon Suk CHA ; Jin Seok KIM ; Eun Mi KOH
The Journal of the Korean Rheumatism Association 1998;5(1):76-82
OBJECTIVE: Adult onset Still s disease is an acute systemic inflammatory disorder. There are no pathognomonic symptoms or specific laboratory abnormalities. In recent reports, serum ferritin concentration is increased in active disease phase and decreased after defervescence. Our purpose was to determine the clinical significance of serum ferritin as an indicator for disease activity. METHODS: Seven patients who were diagnosed as adult onset Still s disease at Samsung Medical Center between October 1994 and March 1997, were reviewed. In these patients we checked leukocyte count, ESR, CRP and serum ferritin concentrations at the time of diagnosis and during follow-up periods and recorded febrile events during follow-up periods. RESULTS: At the time of diagnosis and during febrile periods, the concentrations of ferritin were extremely high(927ng/ml to 96,650ng/ml normal 10-290.8 ng/ml). The values were unrelated to other manifestations of the disease or laboratory findings. The ferritin concentrations decreased rapidly after adequate treatment. Eleven febrile reattacks happened in 7 patients. Serum ferritin concentrations were increased in 8 febrile attacks, while leukocyte count, ESR, and CRP were increased in 5, 5, 6 febrile attacks respectively, There were 10 events of increased serum ferritin concentrations in 7 patients during follow-up periods and 8 events were related with fever. The increases of other laboratory tests were similar. CONCLUSIONS: In all patients, serum ferritin concentrations were increased at the time of diagnosis and closely related to fever. During follow-up periods, serum ferritin concentrations are helpful in monitoring disease activity and guiding decisions about treatment.
Adult*
;
Diagnosis
;
Ferritins*
;
Fever
;
Follow-Up Studies
;
Humans
;
Leukocyte Count
;
Still's Disease, Adult-Onset*
7.Budd-Chiari syndrome caused by membranous obstruction of inferior vena cava.
Yong Bok KOH ; Seung Jin YOO ; Yong Pil WANG ; Seok Won LIM
Journal of the Korean Surgical Society 1991;41(4):554-563
No abstract available.
Budd-Chiari Syndrome*
;
Vena Cava, Inferior*
8.Initial Experience of Three Cases of Radical Retropubic Prostatectomy.
Korean Journal of Urology 1989;30(6):907-911
From December 1986 to August 1988, three patients with early prostatic cancer diagnosed primarily by fine needle aspriation cytology and/or Tru-cut needle biopsy underwent potency preserving radical retropubic prostatectomy. Herin we report the results and associated problems. Most difficulty was the diagnosis of the early prostatic cancer. We used fine needle aspiration cytology to diagnose the prostatic cancer primarily. One case of class V on the preoperative cytologic examination has proved to be BPH with chronic prostatitis postoperatively. Another problem was possibility of major bleeding intraoperatively, and complications were uncommon and not serious.
Biopsy, Fine-Needle
;
Biopsy, Needle
;
Diagnosis
;
Hemorrhage
;
Humans
;
Needles
;
Prostatectomy*
;
Prostatic Neoplasms
;
Prostatitis
9.Initial Experience of Three Cases of Radical Retropubic Prostatectomy.
Korean Journal of Urology 1989;30(6):907-911
From December 1986 to August 1988, three patients with early prostatic cancer diagnosed primarily by fine needle aspriation cytology and/or Tru-cut needle biopsy underwent potency preserving radical retropubic prostatectomy. Herin we report the results and associated problems. Most difficulty was the diagnosis of the early prostatic cancer. We used fine needle aspiration cytology to diagnose the prostatic cancer primarily. One case of class V on the preoperative cytologic examination has proved to be BPH with chronic prostatitis postoperatively. Another problem was possibility of major bleeding intraoperatively, and complications were uncommon and not serious.
Biopsy, Fine-Needle
;
Biopsy, Needle
;
Diagnosis
;
Hemorrhage
;
Humans
;
Needles
;
Prostatectomy*
;
Prostatic Neoplasms
;
Prostatitis
10.Complex Conjunctival Choristoma in Linear Nevus Sebaceous Syndrome: A case report.
Jinyoung YOO ; Jae Kyung KOH ; Seok Jin KANG ; Byung Kee KIM
Korean Journal of Pathology 2000;34(9):680-684
Linear nevus sebaceous syndrome is an uncommon neurocutaneous disorder characterized by nevus sebaceus, seizures, and mental retardation, and is often accompanied by ocular anormalies. We recently experienced a case of conjunctival choristoma associated with linear nevus sebaceous syndrome in a 17-month-old boy. The child was the product of a full-term uncomplicated pregnancy and normal delivery with normal karyotype of 46, XY. He was noted at birth to have a conjunctival mass on the right eye and linear nevi over the midline facial region and right temporoparietal scalp. Ophthalmologic examination revealed optic atrophy, peripapillary staphyloma, macular hypogenesis, and osseous choristoma of the choroid. A computed tomography scan demonstrated widening of the subarachnoid space and moderate atrophy of the cerebral and cerebellar hemispheres. He has been followed by ophthalmology and completely free of seizures since birth. The patient underwent excision of the conjunctival mass and biopsies of the skin lesion at 17 months of age. Histologic examination of the skin biopsies was characteristic for the linear sebaceous nevus of Jadassohn. Histologic findings of the conjunctival lesion showed a complex choristoma that contained lacrimal gland tissue and cartilage.
Atrophy
;
Biopsy
;
Cartilage
;
Child
;
Choristoma*
;
Choroid
;
Humans
;
Infant
;
Intellectual Disability
;
Karyotype
;
Lacrimal Apparatus
;
Male
;
Neurocutaneous Syndromes
;
Nevus*
;
Nevus, Sebaceous of Jadassohn
;
Ophthalmology
;
Optic Atrophy
;
Parturition
;
Pregnancy
;
Scalp
;
Seizures
;
Skin
;
Subarachnoid Space