1.Effects of Mindfulness-based Stress Reduction Program on Perceived Stress, Internalized Stigma, and Psychological Well-being in Psychiatric Inpatients
Journal of Korean Academy of Psychiatric and Mental Health Nursing 2023;32(3):259-269
Purpose:
The aim of the study was to investigate the effects of a mindfulness-based stress reduction program on the perceived stress, internalized stigma, and psychological well-being of psychiatric inpatients.
Methods:
A non-equivalent control group study with a pretest-posttest design was used. Participants were obtained from the closed wards of a psychiatric hospital in K-city. A total of 45 people were included in this study, 22 in the experimental group and 23 in the control group. The pre, post, and follow-up scores of both the experimental and control groups were obtained using the Korea Perceived Stress Scale, the Korea Internalized Stigma of Mental Illness Scale, and the Korea Psychological Well-Being Scale to validate the effectiveness of the program. A 45 minute program was performed twice weekly for three weeks.
Results:
There was a statistically significant reduction in perceived stress (F=6.92, p=.002) and internalized stigma (F=22.76, p<.001), and a significant improvement in psychological well-being (F=38.34, p<.001) in the experimental group.
Conclusion
A mindfulness-based stress reduction program could be implemented as an intervention to reduce perceived stress and internalized stigma and enhance psychological well-being in psychiatric inpatients.
2.Duodenal Somatostatinoma: A case report.
Mee Hye OH ; Yi Kyeong CHUN ; Hye Jae CHO ; Jin Ho LEE ; Hong Yong KIM ; Ill Hyang KO
Korean Journal of Pathology 1993;27(6):645-649
Somatostatinoma is rare endocrine tumor that was first described in 1977 by Ganda et al. and Larsson et al. simultaneously. It seems nonfunctioning at clinical level. But it may present with diabetes, diarrhea, cholelithiasis, steatorrhea, indigestion, hypochlorhydria, and anemia. In contrast with pancreatic somatostatinoma, duodenal somatostatinoma, in general, is clinically silent. Duodenal endocrine tumors show similar histologic pattern. Therefore, the definite diagnosis is performed by immunohistochemistry and electron microscopic examination. We have experienced a case of somatostatinoma of duodenum in a 62-year-old male. He has complained generalized pruritus for one year and jaundice for 2 weeks. Grossly, the mass was a intraluminary protruding, polypoid lesion with focal mucosal erosion at immediately distal to Ampulla of Vater. Histologically, it showed tall, cylindrical cells with distinct cell membranes, having granular cytoplasm and small innocent looking nuclei. No mitosis was seen. The tumor cells were arraged in small solid groups and trabeculae, separated by fibrovascular stroma. Immunohistochemically, the tumor cells were strongly positive with somatostatin and negative with several other hormonal and neuroendocrine markers. Ultrastructurally, the cytoplasm contains numerous, homogeneous low electron dense secretory granules, which are essentially similar to those seen in normal delta cells.
3.Relationship between Carcinoembryonic Antigen (CEA) and Pulmonary Function in Middle-aged Male Smokers.
Byoung Joon MOON ; Dong Jin LEE ; Kyeong Duk KO ; Sun Woo YANG ; Kyeong Su CHUN ; Mi Kyeong OH
Journal of the Korean Academy of Family Medicine 2002;23(7):925-933
BACKGROUND: Carcinoembryonic antigen (CEA) is a glycoprotein on cellular surface, which is highly condensed in embryonic tissue and tumor of various kinds. Previous study found out that CEA may grow with various cancer or other diseases other than cancer as well. Besides, it is widely known that smoking also influences the rise in CEA. Among the same smokers, some of them show high CEA figures in serum when others remain in normal range. There are those whose pulmonary function is not influenced by smoking when that of others are susceptible to it. Therefore, this study was undertaken with an aim to study the relationship between serum CEA and pulmonary function by investigating how the change in pulmonary function caused by smoking influences serum CEA. METHODS: From Nov, 1997 to Feb, 2001, this study carried out tests on adult male smokers ages 35 to 64 who visited a hospital located in Kang Nung city. The subjects were divided into two groups: one group of 29 subjects with high CEA with over 6.0 ng/ml with normal colon study; the other group, which is the CEA normal group, consisted of 58 subjects selected through age adjusted random sampling. Data on personal information, smoking and clinical history was collected from a questionnaire. CEA was tested using radioimmunoassay of Abott. Pulmonary function was examined using Analyzer assembly Vmax 20C from Sensormedics Company. These examinations was limited to those who have been screened not to have cancer by chest X-ray, abdominal ultrasonography, and duodenofibroscopy. RESULTS: Smoking per day for the group with high serum CEA was 1.3 pack ( 0.4 pack), which was found to be significantly higher compared to that of normal group (P<0.01). Pack-years with high serum CEA group was 32.6 13.5 which was also comparatively higher than that of the normal group with 22.4 10.9 (P<0.01). Pulmonary function test indicated that FEV1 for the group with high serum CEA was 3.0 0.5 L, which marked lower than that of the normal group with 3.4 0.5 L (P<0.05). After compensating for age and pack years, FEV1 decreased in proportion to the rise in CEA. CONCLUSION: This study has established a link between serum CEA and daily smoking, pack years, and pulmonary function and found that FEV1 was inversely proportionate to the rise in CEA regardless of corrected pack years and daily smoking. Consequently, serum CEA alone is thought to be related to the pulmonary function. Therefore, it is advised that smokers with high serum CEA need to take heed of the influence on pulmonary function.
Adult
;
Carcinoembryonic Antigen*
;
Colon
;
Glycoproteins
;
Humans
;
Male*
;
Radioimmunoassay
;
Reference Values
;
Respiratory Function Tests
;
Smoke
;
Smoking
;
Thorax
;
Ultrasonography
;
Surveys and Questionnaires
4.Risk Factors of New Adjacent Compression Fracture after Percutaneous Vertebroplasty: Effectiveness of Bisphosphonate in Osteoporotic or Osteopenic Elderly Patients.
Dae Hyun SEO ; Si Hyuck OH ; Kyeong Wook YOON ; Jung Ho KO ; Young Jin KIM ; Jee Young LEE
Korean Journal of Neurotrauma 2014;10(2):86-91
OBJECTIVE: The purpose of this study is to investigate the incidence of new compression and to analyze factors that influence the fractures in adjacent levels after percutaneous vertebroplasty (PVP). METHODS: This retrospective study examined 206 patients who had undergone PVP for single level osteoporotic or osteopenic compression fractures during the last seven years in our department. After PVP, the patients were observed for at least over one year, and 29 patients showed new additional compression fractures in adjacent levels. One hundred seventy seven patients who did not show additional compression fractures were analyzed as the control group. Statistical comparisons were performed between the groups, in terms of age, gender, bone mineral density, whether bisphosphonate (BPP) was treated, preoperative kyphosis, preoperative wedge angle, change in wedge angle, amount of bone cement, existence of intradiscal bone cement leakage, and initial fracture levels. RESULTS: The statistically significant factors that influence new compression fractures in adjacent levels after PVP were as follows: being female, initial thoracolumbar junction fracture, preoperative large kyphotic, preoperative large wedge angle, change in wedge angle, administration of BPP in osteopenia group, and intradiscal cement leakage. CONCLUSION: This study identified many factors that influence newly developed compression fractures in adjacent levels after PVP. Interestingly, the administration of BPP in osteopenia group had positive influence on new fractures in this study. Therefore, we recommend early administration of BPP to patients with osteopenia.
Aged*
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Bone Density
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Bone Diseases, Metabolic
;
Diphosphonates
;
Female
;
Fractures, Compression*
;
Humans
;
Incidence
;
Kyphosis
;
Retrospective Studies
;
Risk Factors*
;
Spinal Fractures
;
Vertebroplasty*
5.Effect of Electrocauterization on the Inflammation of the Conjunctiva in Experimental Animal Model.
Kyeong Hwan KIM ; Ah Young KO ; Jin Suk RYU ; Mee Kum KIM ; Won Ryang WEE
Korean Journal of Ophthalmology 2013;27(4):282-287
PURPOSE: Recently, conjunctivochalasis repair surgery using electrocauterization has been gaining popularity. However, patients with electrocauterized conjunctivoplasty tend to complain of more postoperative pain than patients undergoing simple excision with suturing. Therefore, we investigated the effects of electrocauterization on inflammation of the conjunctiva using an experimental animal model and compared these with the effects of simple excision with suturing. METHODS: Ten New Zealand white rabbits underwent cauterization in the right eyes and excision and suturing in the left eyes. For each eye, we excised or electrocauterized the inferior bulbar conjunctiva, 1 mm in width and 6 mm in length, 2 mm from the limbus. A fine-needle electrode was inserted subconjunctivally, and electrocauterization was performed. In the contralateral eye, the corresponding area was excised and re-approximated with 10-0 nylon sutures. Sutures were removed after 14 days. Tissue samples were obtained at 21 days post-procedure, and inflammatory cells were counted in five randomly selected fields (x200) on hematoxylin-eosin stained slides. Tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta concentrations in tears were measured using enzyme linked immunosorbent assays. RESULTS: All cauterized eyes demonstrated smooth surface healing without scarring after 5 days, whereas sutured eyes presented with mild edema with some scarring until the suture was removed. The number of inflammatory cells was significantly greater in sutured eyes compared with cauterized eyes (p = 0.035, Mann-Whitney U-test) at 21 days post-procedure. Tear TNF-alpha and IL-1beta concentrations at 21 days were similar in both groups. CONCLUSIONS: Electrocauterization for conjunctivoplasty seems to be advantageous in terms of inflammation compared with simple suturing and excision.
Animals
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Conjunctiva/pathology
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Conjunctivitis/*pathology/*surgery
;
Disease Models, Animal
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Edema/pathology/prevention & control
;
Electrocoagulation/*methods
;
Humans
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Male
;
Pain, Postoperative/pathology/*prevention & control
;
Rabbits
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*Suture Techniques
;
Treatment Outcome
6.Comparison of procedural sequence in same-day bidirectional endoscopy: a systematic review and meta-analysis
Geun Joo CHOI ; Hyoung-Chul OH ; Hee-Kyeong SEONG ; Jeong Wook KIM ; Jin Soo KO ; Hyun KANG
The Korean Journal of Internal Medicine 2020;35(2):331-341
Background/Aims:
To compare the efficacy and safety of procedural sequence in same-day bidirectional endoscopy.
Methods:
We searched OVID-MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Google Scholar to identify randomized controlled trials that compared the procedural sequences in same-day bidirectional endoscopy, including esophagogastroduodenoscopy (EGD) and colonoscopy. The sedative and analgesic doses required, discomfort and satisfaction scores, procedure time, recovery time, adenoma detection rate, and failed cecal intubation were evaluated. Adverse effects, including respiratory and cardiovascular complications, were also assessed.
Results:
We included six studies, with 1,848 patients in total. The requirement for sedative treatment was significantly lesser in the EGD-colonoscopy sequence than in the colonoscopy-EGD sequence (standardized mean difference [SMD], –0.39; 95% confidence interval [CI], –0.54 to –0.24; p = 0.12; I2 = 49%). Discomfort, scored by patients during the EGD procedure, was significantly lesser in the EGD-colonoscopy sequence than in the colonoscopy-EGD sequence (SMD, –0.45; 95% CI, –0.80 to –0.09; p = 0.02; I2 = 73%), while it was comparable during colonoscopy between the two sequences. Recovery time was significantly shorter in the EGD-colonoscopy sequence than in the colonoscopy-EGD sequence (SMD, –0.47; 95% CI, –0.65 to –0.30; p = 0.28; I2 = 21%). Total procedure duration, EGD, colonoscopy, cecal intubation time and incidence, incidences of pathologic findings, and adenoma detection were comparable between the two sequences. There was no significant difference in the incidences of desaturation, hypotension, hypertension, bradycardia, and tachycardia between the two sequences.
Conclusions
When conducting same-day bidirectional endoscopy, EGD followed by colonoscopy is the most beneficial sequence to be used because patients require lower sedative doses, recover faster, and report lesser discomfort.
7.Left Ventricular Thrombus Associated with Takotsubo Cardiomyopathy: A Cardioembolic Cause of Cerebral Infarction.
Seoung Nam SHIN ; Kyeong Ho YUN ; Jum Suk KO ; Sang Jae RHEE ; Nam Jin YOO ; Nam Ho KIM ; Seok Kyu OH ; Jin Won JEONG
Journal of Cardiovascular Ultrasound 2011;19(3):152-155
Takotsubo cardiomyopathy, also called stress-induced cardiomyopathy, usually occurs in patients with severe emotional or physiologic stress. The prognosis is favorable, and the wall motion abnormlities normalize within weeks. However, stress-induced cardiomyopathy is rarely assosicated with left ventricular thrombus and thromboembolic complications. Here, we report a case of stress-induced cardiomyopathy with left ventricular thrombus that embolized to cause cerebral infarction.
Cardiomyopathies
;
Cerebral Infarction
;
Humans
;
Prognosis
;
Takotsubo Cardiomyopathy
;
Thrombosis
8.Long-Term Predictors of Clinical Events after Off-Label Use of Drug-Eluting Stent beyond 1 Year.
Kyeong Ho YUN ; Jum Suk KO ; Sang Jae RHEE ; Eun Mi LEE ; Nam Jin YOO ; Nam Ho KIM ; Seok Kyu OH ; Jin Won JEONG
Korean Circulation Journal 2013;43(3):161-167
BACKGROUND AND OBJECTIVES: We evaluated the long-term outcomes and predictors of clinical events after off-label use of drug-eluting stents (DES) beyond 1 year after procedure. SUBJECTS AND METHODS: A total of 518 patients who underwent DES implantation for off-label indications and did not have any major adverse cardiac events (MACE) during the first year were analyzed. The occurrence of MACE, including cardiac death, myocardial infarction (MI), stent thrombosis and target vessel revascularization, were evaluated for a median 1179 days (interquartile range 769-1541) after the first year. RESULTS: Major adverse cardiac events occurred in 43 patients (8.3%) including 8 cases (1.5%) of cardiac death, 9 cases (1.7%) of MI, 24 cases (4.6%) of target vessel revascularization, and 11 cases (2.1%) of stent thrombosis. Patients with MACE had a higher serum creatinine level, higher incidence of in-stent restenosis lesion, more overlapping stents, a greater number of stents, and longer stents than did patients without MACE. Multivariate analysis revealed that serum creatinine level >1.5 mg/dL {hazard ratio (HR) 2.3, p=0.019}, stent length >33 mm (HR 2.4, p=0.035), and in-stent restenosis lesions (HR 2.4, p=0.040) were independent risk factors for MACE. Patients with DES length >33 mm had a higher incidence of MACE than those with DES length < or =33 mm (HR 2.7, log rank p=0.002). CONCLUSION: The risk of stent thrombosis and target vessel revascularization persisted in patients undergoing off-label DES implantation beyond 1-year follow-up. A total DES length >33 mm was a significant procedural predictor associated with the incidence of MACE.
Angioplasty
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Coronary Thrombosis
;
Creatinine
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Death
;
Drug-Eluting Stents
;
Follow-Up Studies
;
Humans
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Incidence
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Multivariate Analysis
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Myocardial Infarction
;
Off-Label Use
;
Risk Factors
;
Stents
;
Thrombosis
;
Treatment Outcome
9.The Number of Endothelial Progenitor Cells is Decreased in Patients With Non-Dipper Hypertension.
Seunghwan KIM ; Nam Ho KIM ; Yong Kwon KIM ; Jong Hyun YOO ; Seong Nam SHIN ; Jum Suk KO ; Yun Kyeong KIM ; Sang Jae RHEE ; Kyeong Ho YUN ; Eun Mi LEE ; Nam Jin YOO ; Seok Kyu OH ; Jin Won JEONG
Korean Circulation Journal 2012;42(5):329-334
BACKGROUND AND OBJECTIVES: Circulating endothelial progenitor cells (EPCs) play a key role in the maintenance of endothelial homeostasis and promote vascular repair. A reduced number of EPCs and the functional activity have been associated with several cardiovascular risk factors. However, the relationship between the number of EPCs and circadian rhythm of the blood pressure (BP) remains unclear. The purpose of the present study was to evaluate the relationship between the circadian rhythm of the BP and EPCs in patients with essential hypertension. SUBJECTS AND METHODS: A total of 45 patients with essential hypertension who were newly identified by outpatient BP measurements, underwent 24-hour ambulatory BP monitoring. Among the 45 patients with essential hypertension, 20 were classified as dippers (12 men and 8 women; mean age 48+/-14 years) and 25 as non-dippers (14 men and 11 women; mean age 52+/-18 years). The EPC count was isolated from the peripheral bloodstream and quantified by flow cytometry. RESULTS: The baseline clinical characteristics were similar between the dipper and non-dipper hypertensive patients. The circulating EPCs were statistically reduced in the non-dipper patients as compared to the dippers (104+/-60 vs. 66+/-47 EPCs per 106 mononuclear cells, p=0.027). The circulating EPC level correlated positively with the circadian changes in the systolic and diastolic BP (r=0.435, p=0.003, and r=0.310, p=0.038, respectively). CONCLUSION: The present study demonstrated that the EPC count was reduced in the peripheral bloodstream in non-dipper hypertensive patients.
Blood Pressure
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Circadian Rhythm
;
Homeostasis
;
Humans
;
Hypertension
;
Male
;
Outpatients
;
Phosphorylcholine
;
Risk Factors
;
Stem Cells
10.Neuroendoscopic Removal of Large Choroid Plexus Cyst: A Case Report.
Jin Ho JEON ; Sang Weon LEE ; Jun Kyeong KO ; Byeong Gwan CHOI ; Seung Heon CHA ; Geun Seong SONG ; Chang Hwa CHOI
Journal of Korean Medical Science 2005;20(2):335-339
Choroid plexus cysts (CPCs) are the most commom neuroepithelial cysts, occuring in more than 50% of some autopsy series. They are typically small and asymptomatic and are discovered incidentally in older patients, usually in the trigone of the lateral ventricle. Symptomatic CPCs (usually exceptionally large, 2-8 cm) are rare. The authors report a case of large symptomatic choroid plexus cyst, located in the trigone of the right lateral ventricle in a 26-yr-old man who presented with headache and vomiting. The patient underwent endoscopic removal through a burr hole placed 3 cm from the midline and just behind the hair line. The histological examination of the cyst wall was consistent with choroid epithelium. Despite of postoperative intraventricular hemorrhage and catheter infection, he discharged home without neurologic deficits. The endoscopic fenestration rather than excision should be considered as the first surgical procedure because the goal of treatment is shrinkage of the cyst until normal cerebrospinal fluid flow is restored.
Adult
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Brain Diseases/diagnosis/pathology/*surgery
;
*Choroid Plexus
;
Cysts/diagnosis/pathology/*surgery
;
Endoscopy
;
Humans
;
Male