No abstract available.
Creatinine*

No abstract available.
Classification*

Telomerase is an RNA-dependent DNA polymerase that synthesizes TTAGGG telomeric DNA onto chromosomal ends to compensate for sequence loss during replication. It has been detected in a variety of human malignancies, suggesting that such activity may play a role in the tumorigenic process. To determine whether telomerase is reactivated in malignant fibrous histiocytoma, 12 tissue samples with this tumor were analyzed for the telomerase activity by a radioactive PCR-based TRAP (telomeric repeat amplification protocol) assay. All of the tumors were further investigated for the expression of human telomerase RNA (hTR) by an in situ hybridization (ISH). Telomerase activity was detected in one (8.3%) sample. Expression of hTR was demonstrated in 7 (58.3%): one telomerase-positive and six telomerase-negatives. These data indicate that the reactivation of telomerase is an uncommon event and not an important factor involved in tumorigenesis in malignant fibrous histiocytoma. It is noteworthy that 50% of the patients with grade 2 tumors expressed hTR, suggesting that telomerase RNA may be useful as a marker for identifying tumor aggressiveness earlier than the conventional histopathologic grading scale.
Carcinogenesis ; DNA ; Histiocytoma, Malignant Fibrous* ; Humans ; In Situ Hybridization ; RNA* ; RNA-Directed DNA Polymerase ; Telomerase*

128 individuals with tattoos, who were seen during physical examination for conscription from February to May, 1985, were taken for a clinical study of tattoos. The results were as follows: 1. The color of the tattoos were blue-black or light blue. The materials most commonly employed were Chinese ink stick and others were Chinese ink, black ink, blue ink, and smokeless coal powder. 2. The tattoos were made by tattooed themselves or by their friends and sewing needles were punctured to introduce particles of pigment into the skin in all cases. 3. As to the sites of tattoos, left forearm was the favorite(42.4%) and others were left upper arm(28. l%), right forearm(5. 5%), right upper arm(5 1%) etc. 4. Among 271 tattoos of 100 kinds, a rose was most frequently seen(5. 9%) and others were a symbol of love(4. 8%), a butterfly(4.l%), - I (one mind) (3.7%), patience (3. 7%) etc. 5. The complications of tattooing were found in 8. 6p, of the tattooed and they were pyoderma, hypertrophic scar, keloid, lymphadenopathy, post-inflammatory ]yper-and hypopigmentation, and scar formation about tattoos. 6. The removd of tatoos were tried all by tattooed themselves. The most frequent method used was scratching up with a knife and others were cigarette burn, attatchment of bean-curd, rubbing with salt, and chemical burns with hydrochloric acid. etc.
Asian Continental Ancestry Group ; Burns ; Burns, Chemical ; Cicatrix ; Cicatrix, Hypertrophic ; Coal ; Forearm ; Friends ; Humans ; Hydrochloric Acid ; Hypopigmentation ; Ink ; Keloid ; Lobeline ; Lymphatic Diseases ; Needles ; Physical Examination ; Pyoderma ; Skin ; Tattooing ; Tobacco Products

No abstract available.
Adenosine Triphosphatases* ; Animals ; Langerhans Cells* ; Mice* ; Oxygen*

We describe herein a case of tick bite ocurring to a 23-year-old man who has a characteristic lesion clinically and histopathologically. The tick(Ixodes sp.) was still attached to the brownish and erythematous, indurated skin of the scrotum. The engorged tick which was carefully removed from the skin with a scalpel was 8.7mm in length and 5. 5 mm in width. Histopathologically, characteristic amorphous eosinophilic materigl is deposited around a round space where the hypostorne of the tick was inserted. Heavy inflammatory cell infiltratton in the mid and lower dermis is composed mainly of neutrophils and eosinophils. A certain area of the lower dermis shows edema and capillary dilatation along with the mixed inflammatory cell infiltration, TVide excision of the indurated lesion including the tick was done. The clinical and hsitopathological findings of the tick bite was discussed.
Capillaries ; Dermis ; Dilatation ; Edema ; Eosinophils ; Humans ; Neutrophils ; Scrotum ; Skin ; Tick Bites* ; Ticks* ; Young Adult

Annular elastolytic giant cell granuloma(AEGC(3) has been called as atypical necrcibiosis lipoidica, Mieschers granuloma of the face and scalp, and actinic granu- Joma and needs differen(iation from granuloma annulare, elastosis perforans serpiginosa and nerrobiosis lipoidica. We report a case of AECCG occurring in a 53-year-old male. The patient. had an annular erythematous plaque measuring 4 cm in diameter with serpiginous raised edges and slightly atrophic centers on the right forearm for 5 years. The histopathologic finding showed patchy dermal infiltration of lymphocytes, histiocytes, and multinucleated giant cells engulfing elastic fibers. The. skin lesion cleared after intrader mal injection cf cortieosteroids.
Actins ; Elastic Tissue ; Forearm ; Giant Cells* ; Granuloma ; Granuloma Annulare ; Granuloma, Giant Cell* ; Histiocytes ; Humans ; Lymphocytes ; Male ; Middle Aged ; Scalp ; Skin

No abstract available.
Neoplasm Metastasis* ; Perfusion*

No abstract available.
Silver*

We analysed the results of total knee replacement arthroplasty without patellar resurfacing in 20 patients(28 knees) retrospectively. The patella was not resurfaced when it maintained relatively healthy cartilage in osteoarthritis or the patella was too thin to be replaced in rheumatoid arthritis. The diagnoses were osteoarthritis in 11 and rheumatoid arthritis in 17 cases. The follow up period was 30.3 months in average(12-70 months). A lateral retinacular release was performed in 22 knees(78.6%). The mean knee society score improved from 45.4 preoperatively to 84.1 postoperatively and the functional score improved from 21.4 preoperatively to 63.3 postoperatively. The modified Kujala score was 43.2 points in osteoarthritis and 43.6 points in rheumatoid arthritis. We conclude the total knee replacement arthroplasty without patellar resurfacing shows good results, without high risk of postoperative peripatellar complication.
Arthritis, Rheumatoid ; Arthroplasty* ; Arthroplasty, Replacement, Knee* ; Cartilage ; Diagnosis ; Follow-Up Studies ; Knee ; Osteoarthritis ; Patella ; Retrospective Studies