No abstract available.
Humans ; Infant, Newborn*

We roport herein three cases of pruritic urticarial papules and plaques of pregnancy in two primigravidas and one multigravida in erythematous papules and urticarial plaques on both thighs, buttock and upper extremites. In the second case, lesions initially developed on both thighs and then preaded on abdomen, back and exter ities. Abdomen, thighs and extremites were involved in the third case. Histopathologic findings revealed acanthosis orfocal spongiosis in epidermis and lymphocytic perivascular infiltration with or without eosinophilsn dermis. They were treated with systemiror topical steroids and, mtihistamines. Itching was relieved within a few days after therapy and skin lesions resolved spontaneously after delivery.
Abdomen ; Buttocks ; Dermis ; Epidermis ; Pregnancy* ; Pruritus ; Skin ; Steroids ; Thigh

Baboon syndrome is used to denote a systemic allergic contact dermititis with a characteristic color and distribution pattern. It is also referred to as mercury exanthem, because inhalation of mercury vapor usually causes the skiri lesion in a sensitized person. Diffuse pi,ikish erythema of the buttock, upper inner thigh, and axilla are characteristic features. We report a case of baboon syndrome developed after exposure to the smoke of a burning amulete a charm written on a piece of paper in a 12 year-old female. Mercury sensitivity was confirrned by a patch test. Atomic absorption by a spectrographic method and Scanning electron microscopy/energy dispersive for analysis X-ray detected mercury in the urine and the ed scraped pigments from the amulet, respectively.
Absorption ; Axilla ; Burns ; Buttocks ; Child ; Erythema ; Exanthema ; Female ; Humans ; Inhalation ; Papio* ; Patch Tests ; Smoke* ; Thigh

BACKGROUND: Plant extracts have been widely used as important therapeutic drugs for many centuries all over the world. There have been many reports that natural products have various kinds of biological activities such as anti-allergy, anti-inflammatory and antimicrobial activities. Recently, the screening for the efficacy and safety of natural products has been extensively performed. OBJECTIVE: This study was carried out to find a beneficial plant extract possessing excellent antioxidative and anti-melanogenic activities. We have found that the leaf of Robinia pseudo-acacia L. has active substances which are involved in those activities. METHODS: To confirm the antioxidative activity of the extract obtained from the leaves of Robinia pseudo-acacia L., scavenging ability of the extract on DPPH free radicals and its inhibitory effects on lipid autoxidation and peroxidation were investigated. In addition, inhibitory effects of the extract on mushroom tyrosinase as well as melanin biosynthesis in cultured B16 melanoma cells were evaluated. RESULTS: The acacia extract showed not only powerful antioxidative activity but also antimelanogenic acitivity as strong as that of arbutin which is a well known inhibitor of melanogenesis. CONCLUSION: These resulis suggest that the extract from the leaves of Robinia pseudo-acacia L. could be used as a 4ghtening and antioxidative agent for the skin.
Acacia ; Agaricales ; Arbutin ; Biological Products ; Free Radicals ; Mass Screening ; Melanins ; Melanoma, Experimental ; Monophenol Monooxygenase ; Plant Extracts ; Plants ; Robinia* ; Skin

No abstract available.
Neoplasm Metastasis* ; Perfusion*

No abstract available.

In order to study the clinical characteristics of primary acute angle closure glaucoma, we analyzed the data of 72 eyes from 63 patients with the disease from January 1, 1990 to December 31, 1993 to the Department of Ophthalmology of Chonnam University Hospital. The mean age of the patients was 63.3 years and female and male ratio was 5.9:1. And the mean IOP at first visit was 53.2 mmHg. There was no significant difference of rop between right and left eyes, and 11 patients had the disease in both eyes. 38% of the patients developed the disease in winter time. The development of the disease was closely associated with physical illness and emotional stress. 39 eyes(49.3%) of them was required filtering surgery because medication and laser treatment was insufficient to lower IOP.
Female ; Filtering Surgery ; Glaucoma, Angle-Closure* ; Humans ; Jeollanam-do ; Male ; Ophthalmology ; Stress, Psychological ; Trabeculectomy

Acanthoma fissuratum is a localized thickening of the skin in response to pressure by an eyeglass frame and usually occurs on the retroauricular fold, superior auricular crease, or bridge of the nose. The definitive diagnosis can be confirmed by characteristic clinical and histopathological features in association with anamnestic data. Herein we report a case of acanthoma fissuratum developing on an unusual site-the mucosa of the upper lip and it was successfully treated with simple excision.
Acanthoma* ; Diagnosis ; Lip* ; Mucous Membrane* ; Nose ; Skin

BACKGROUND: Canine scabies is caused by an infestation of Sarcoptes scabiei var. canis (S. canis) in dogs and they can be transmitted to humans. Recently pet raising has been increasing in Korea and various parasitic infestations contracted from them have also been increasing including canine scabies. OBJECTIVE: The purpose of this study was to examine the clinical and histopathological features of experimental canine scabies. METHODS: Two dogs experimentally infested were observed for a year. They were examined physically and the numbers of S. cans were counted from scraping samples of the ear, leg and abdomen every 3 to 7 days and skin biopsies were taken. One was given systemic corticosteroids(Dogl) and the other was observed in its natural course(Dog2). RESULTS: Dogl-Clinically severely pruritic, markedly thick hyperkeratotic scales, crust and generalized erythema on the whole body developed with huge numbers(up to 754.9/100mg from scales of the abdomen) of mites, and histopathologically showed features similar to human crusted scabies. Dog2-Clinically showed milder features than Dogl including the number of S. canis(up to 242.6/100mg from scales of the ear), but histopathologically showed similar features with Dogl. Dog2 also showed a prompt response to one topical application of 20% benzyl benzoate solution. CONCLUSIONS: 1) The number of S. canis increased markedly in both normal and corticosteroidtreated dogs, although it was more significantly increased in the corticosteroid-treated one. 2) Histopathology showed features similar to classical scabies in the early stage but features of human crusted scabies in the full-blown stage. 3) Morphologically Sarcoptes canis differs from Sarcoptes scabiei var. hominis.
Abdomen ; Animals ; Benzoates ; Biopsy ; Dogs ; Ear ; Erythema ; Humans ; Korea ; Leg ; Mites ; Sarcoptes scabiei ; Scabies* ; Skin ; Weights and Measures

We recently encountered a case of pemphigus vulgaris, which was localized within the oral mucosa and esophagus. The patient was a 62-year-old women, who had had a few recurrent erosions on the oral mucosa for 1 year. Newly developed erythematous erosions on the esophagus appeared 7 days pre previously. Histopathological findings showed suprabasal blisters in the epithelium of the buccal and esophageal mucosa. On direct immunofluorescence, intercellular IgG and C3 bindings were found in the epithelium of the buccal mucosa. Treatment with oral steroids resulted in a remission of the lesions and the other skin lesions were not found for a period of 6 months.
Blister ; Epithelium ; Esophagus* ; Female ; Fluorescent Antibody Technique, Direct ; Humans ; Immunoglobulin G ; Middle Aged ; Mouth Mucosa* ; Mucous Membrane ; Pemphigus* ; Skin ; Steroids