Anti-HLA antibody related neonatal thrombocytopenia is an uncommon disorder caused by platelet antigen incompatibility between mother and fetus in Korea. Mothers who lack the specific platelet antigen produce the IgG against the platelet antigen which the fetus inherits from the father. These IgG antibodies are then transported across the placenta into the fetal circulation where they lead to the destruction of fetal platelets. We report a case of neonatal alloimmune thrombocytopenia related with anti-HLA antibody in second baby of dizygotic twin who had petechia on trunk and platelet count 43,000/mm. Initially, mother and twin showed the positives in antiplatelet antibodies. In microlym- phocytotoxic test at 6 months of age, anti-HLA antibodies was negative in twins but anti-HLA A2, A24 was positive in their mother. The patient was treated with intravenous immunoglobulin and clinically improved and her platelet count was norrnalized.
Acrocephalosyndactylia* ; Antibodies ; Blood Platelets ; Fathers ; Fetus ; Humans ; Immunoglobulin G ; Immunoglobulins ; Infant, Newborn ; Korea ; Mothers ; Placenta ; Platelet Count ; Thrombocytopenia, Neonatal Alloimmune ; Twins ; Twins, Dizygotic

No abstract available.
Peptic Ulcer Perforation* ; Peptic Ulcer*

No abstract available.

The authors reviewed the clinical findings and treatment results of 12 cases of spinal meningeal cysts which were detected in MRI of low back patients. In these lesions, large cysts without CSF communication can compressed the nerve roots within spinal canal and it is difficult to confirm the cause of symptom whether it is originated from cysts or from associated spinal disorders. The terms and classifications of spinal meningeal cysts were very confusing. Among 12 cases, we excised 3 cases of large cysts with gluteal and perianal pains that were caused by compressed sacral nerve roots. All three cases were type 2 cyst (classified by Nabors) and located in sacral canal. In one case associated with isthmic spondylolisthesis, posterolateral fusion and pedicle screw fixations were combined with cyst excision. In other two cases, there were not any spinal pathologic findings that compressed sacral nerve roots except mild degenerative changes and intervertebral disc herniation in lower lumbar and sacral levels All 3 excised cases showed good prognosis in more than one year follow up. The other cases were treated conservatively for the associated spinal disorders.
Classification ; Follow-Up Studies ; Humans ; Intervertebral Disc ; Magnetic Resonance Imaging ; Prognosis ; Radiculopathy ; Spinal Canal ; Spondylolisthesis

No abstract available.
Cleft Lip* ; Congenital Abnormalities* ; Skin*

No abstract available.
Tenosynovitis*

No abstract available.
Lower Extremity*

Erdheim Chester disease (ECD) is very rare non-Langerhans cell histiocytosis (LCH) which occurs in the skeletal system and multiple organs. As it is progressive, sometimes it causes fatal results. However, it is often misdiagnosed as LCH or multiple bone metastasis and, thus, is very difficult to diagnose. In Korea, only 10 cases were first reported in 1999. In particular, there have been a few orthopedic approaches or reports in English-speaking literatures, and no report has been issued in Korea. The authors performed bone biopsy in patients with knee and lower extremity pain who were referred for the integrated treatment. We attempts to report this diagnosis experience with literature review.
Biopsy ; Erdheim-Chester Disease ; Histiocytosis ; Histiocytosis, Langerhans-Cell ; Humans ; Knee ; Korea ; Lower Extremity ; Neoplasm Metastasis ; Orthopedics

No abstract available.
Hand Injuries* ; Hand*

BACKGROUND: Even though there have been much improvment in general understanding of the climacteric period and increased knowledge of biological aspects of menopause such as Hormone Replacement Therapy, the psychosocial aspects of climacterium was relatively out of consideration. The purpose of this paper is to help make it easy understanding the psychosocial determinants of climacterium through the investigation of correlation between the life stress and the climacteric symptoms in the middle aged women. METHODS: This study was performed on climacteric women at the age ranging from 40 to 55 who reside in Kyong-Ju city. Self reported questionnaires composed of inquiry about demographic characteristics, climacteric symptom scale, and life stress scale were distributed and 123 cases were analyzed in June. and July 1996. The Climacteric Symptom Scale was developed by JG Greene in 1976. In this scale, climacteric symptoms were classified to 3 categories of psychological, somatic, vasomotor symptoms by factor analysis. For quantitative measurement of stress, we used Office Stress Measurement Scale developed by Bae JM et al in 1992. We studied the correlation between stress scores and each class of climacteric symptoms, and the difference of climacteric symptom scores according to the menopausal status and demographic characteristics. RESULTS: The correlation coefficient between the climacteric symptom scores and the stress scores was 0.329(P=0.000) but this correlation was significant in only premenopausal group(correlation coefficient=0.479). Among climacteric symptom classes, the correlation with stress scores is most prominent in psychological symptom class, then somatic symptoms, vasomotor symptoms. There was no difference in climacteric symptom scores to the menopausal status and demographic characteristics. CONCLUSIONS: Women who had more stress complained more climacteric symptoms, especially psychological symptoms. This correlation was significant in the premenopausal group only. And the severity of climacteric symptoms didnt change by demographic characteristics.
Climacteric* ; Female ; Gyeongsangbuk-do ; Hormone Replacement Therapy ; Humans ; Menopause ; Middle Aged ; Self Report ; Stress, Psychological* ; Surveys and Questionnaires