No abstract available.
Stents*

The square face with prominent mandibular angles projects a strong and musculine impression, which is not preferred by most Koreans(may be orientals). Therefore, requests for contouring the prominent mandibular angle are much more common in the orient than in the west. In our study, we treated seven patients with esthetic problem due to prominent mandibular angle using two-step method with intraoral approach via trans- submandibular channel. The advantages of this method are easy measuring, minimized surgical trauma and shortening of the operation time by facilitation of instrumenial application via trans-sumandibular channel.
Humans

No abstract available.
Thymidine

To search biologic characteristics of gastric carcinoma, one of the most common cancer in Korea, the author examined the alterations in DNA level and the expression of Ha-ras gene and c-myc gene in 20 primary tumors. Amplification of c-Ha-ras DNA was detected in 4(40%) of 10 patients who showed histologic subtype of relatively differentiated adenocarcinoma, but rearrangement of c-Ha-ras DNA was absent. Neither augumentation nor deletion of the c-myc DNA was observed. Higher expression of the ras p21 in tumor cells was noted in more differentiated tumor cells rather than poorly differentiated cases. One mucinous carcinoma, two signet ring cell carcinomas and one papillary carcinoma did not disclose expression of p21. The expressions of c-myc oncogene product were variable and were not correspond to the expressions of ras p21. A tendency that poorly differentiated tumor cells had higher expression of c-myc oncogene was suggested.

The diaphragmatic injury results from blunt or penetrating thoracoabdominal trauma. The diagnosis of diaphragmatic injury is difficult in the immediate postinjury period and is often delayed by late visceral herniation. Accurate diagnosis of diaphragmatic injuries is important, because overlooked and delayed diagnosis commonly lead to incarceration and strangulation of bowel. Despite of various diagnostic methods, the diagnosis is often missed and delayed. The development of video-assisted thoracoscopy can make it possible to diagnose the diaphragmatic injury safely and accurately. We experienced two cases of diaphragmatic injuries diagnosed by thoracoscopy. In first case, We found the rupture of the right diaphragm with herniation of liver in a 33-year-old female by thoracoscopic examination. She had visited Emergency Room, complaining of abdominal and pelvic pain and mild dyspnea after traffic accident. Chest X-ray showed elevation of the right hemidiaphragm. Chest CT and ultrasonogram revealed no abnormality except for diaphragmatic elevation. Another case was a 24-year-old female with laceration of diaphragm by stab wound on the left lower chest. With suspicion of diaphragmatic injury, thoracoscopic examination was performed. Both patients were successfully treated by a repair of injured diaphragm by approach via thoracotomy. The postoperative courses were uneventful.
Accidents, Traffic ; Adult ; Delayed Diagnosis ; Diagnosis ; Diaphragm ; Dyspnea ; Emergency Service, Hospital ; Female ; Humans ; Lacerations ; Liver ; Pelvic Pain ; Rupture ; Thoracoscopy* ; Thoracotomy ; Thorax ; Tomography, X-Ray Computed ; Ultrasonography ; Wounds, Stab ; Young Adult

A survey was carried out from August to December 2004 in Pusan, Korea to document the presence of free-living amoeba (FLA), including the genus Acanthamoeba, in both contact lens storage cases and domestic tap water. Acanthamoeba was isolated from 5 (4.2%) in 120 contact lens storage cases. Four house tap water samples from residents, whose contact lens storage cases had been contaminated by Acanthamoeba, were also found to be contaminated with Acanthamoeba. Therefore, the contamination rate of FLA and Acanthamoeba in domestic tap water was investigated in order to examine the role of domestic tap water in Acanthamoeba contamination of contact lens storage cases. FLA and Acanthamoeba were identified in 97 (46.8%) and 16 (7.7%) of the 207 domestic tap water samples, respectively. There were no significant differences between the contamination rates of FLA in tap water according to the filtration plant of origin. No FLA was detected in the tap water directly supplied by the water purification plants. Water storage tanks appear to promote FLA colonization, including Acanthamoeba, in domestic tap water. This increases the risk of Acanthamoeba contamination in contact lens storage cases as well as increasing the risk of Acanthamoeba keratitis.
Acanthamoeba/*isolation & purification ; Amebiasis/epidemiology ; Animals ; Comparative Study ; Contact Lenses/parasitology ; Data Collection ; Humans ; Korea/epidemiology ; Research Support, Non-U.S. Gov't ; Risk Factors ; Water/*parasitology ; Water Supply/*standards

The reciprocal interaction between sleep and pain has been reported by numerous studies. Patients with acute or chronic pain often complain of difficulty falling asleep, frequent awakenings, shorter sleep duration, unrefreshing sleep, and poor sleep quality in general. According to the majority of the experimental human studies, sleep deprivation may produce hyperalgesic changes. The selective disruption of slow wave sleep has shown this effect more consistently, while results after selective REM sleep deprivation remain unclear. Patients with chronic pain have a marked alteration of sleep structure and continuity, such as frequent sleep-stage shifts, increased nocturnal awakenings, decreased slow wave sleep (SWS), decreased rapid eye movement (REM) sleep, and alpha-delta sleep. Many analgesic medications can alter sleep architecture in a manner similar to the effects of acute and chronic pain, suppressing SWS and REM sleep.
Chronic Pain ; Humans ; Sleep Deprivation ; Sleep, REM

No abstract available.

To evaluate the hypotensive effect of dilevalol which has a nonselective blocking action on beta receptors with selective beta2 agonist actcvity, We performed a prospective clinical study for 8 weeks in 31 patients with essential hypertension(mean age : 52+/-9, mean sitting blood pressure : 158/101mmHg) without concomitant heart failure, coronary heart disease, conduction disturbance or renal impairment. The daily dose of dilevalol was 200-400mg. The results were as follows ; 1) After 8 weeks of treatment with dilevalol, average sitting systolic and diastolic blood pressures reduced to 138+/-8mmHg(13%), 84+/-5mmHg(17%) respectively(p<0.01, 0.01). 2) After 8 weeks of treatment with dilevalol, 28(90%) out of the 31 hypertensives showed good hypotensive effect ie, : sitting diastolic blood pressure decreased to below 90mmHg. 3) Pulse rate decreased slightly from pretreatment average of 75+/-8 beats per minute to 70+/-6 beat per minute at the end of 6 weeks of treatment but went back to pretreatment value lastly. 4) Average body weight, serum levels of total cholesterol, HDL cholesterol, triglyceride, AST, ALT, BUN, creatinine, sodium and potassium were not significantly changed from the pretreatment values. 5) A few side effects in order of frequency were epigastralgia, fatigue, cold extremities and dizziness. These results suggest that dilevalil may be used as an effective first line monotherapeutic antihypertensive agent in mild to moderate hypertensives without significant limitations.
Blood Pressure ; Body Weight ; Cholesterol ; Cholesterol, HDL ; Coronary Disease ; Creatinine ; Dizziness ; Extremities ; Fatigue ; Heart Failure ; Heart Rate ; Humans ; Hypertension* ; Labetalol* ; Potassium ; Prospective Studies ; Sodium ; Triglycerides

No abstract available.
Child* ; Heart Arrest, Induced* ; Humans ; Oxygen*