No abstract available.
Case-Control Studies* ; Placenta Previa* ; Placenta* ; Risk Factors*

No abstract available.
Paragonimiasis*

No abstract available in English.
Clinical Study ; Tibial Fractures

The authors have reviewed 119 cases of ligamentous injuries of the knee in 106 patients who were admitted and treated in the department of orthopedic surgery at Kyungpook National Universty Hospital during the period from 1974 to 1983. Patients were analyzed degree of injuries by clinical test, stress radiogram, double contrast radiogram and arthroscopy depend on the cases. Fifteen cases were treated conservatively and 104 cases were repaired the ruptured ligaments operatively, The results were as follows; 1. Ligamentous injuries of the knee were more prevalent in male 4 times than in female, and frequently occured in 3rd and 4th decade, 57 %. 2. Traffic accidents was most common causes, 77.4 % and athletic injuries was next, 15 %. 3. Medial collateral ligements were most commonly ruptured, 68 cases and its femoral attachment was ruptured most commonly, 32 cases. Single ligamentous rupture was most commonly appeared in medial collateral ligament in 36cases. Combined ligamentous rupture were more common in medial collateral ligaments and anterior cruciate ligaments in 15 cases. 4. On follow up examination, knee joint space was compared with both normal and injured knee. In single medial collateral ligamentous rupture, joint space was opened 0.1 mm more than normal side. In combined lesion of lateral collateral ligaments and both cruciate ligamentous rupture, joint space was opened 2.4 mm more than normal side. 5. Excellent and good results were obtained in 88 cases (81%) by operative treatment and 11 cases (73%) by conservative treatment. Early repair of the ligament, under the 2 weeks, gave much better results than later repair. 6. The results were more successful in single ligamentous injuries (55 cases, 87%) than multiligamentous injuries (38 cases, 68%).
Accidents, Traffic ; Anterior Cruciate Ligament ; Arthroscopy ; Athletic Injuries ; Clinical Study ; Collateral Ligaments ; Female ; Follow-Up Studies ; Gyeongsangbuk-do ; Humans ; Joints ; Knee Joint ; Knee ; Lateral Ligament, Ankle ; Ligaments ; Male ; Orthopedics ; Rupture

Real-time ultrasongraphy is a simple, accurate, noninvasive and potentially valuable means of studying gallbladder size and emptying. The authors calculated ultrasonographically the ejection fraction of 80 cases of normally functioning gallbladder on oral cholecystography, from June 1983 to April 1984, at the department of radiology, Hangang Sacred Heart Hospital. The results were obtained as follows; 1. Ultrasongraphic Ejection Fraction at 30 minutes after the fatty meal was 73.1+-16.85. 2. There was no significant difference in age and sex, statistically.
Cholecystography ; Gallbladder ; Heart ; Meals

In an outpatient setting, 107 patients were evaluated using a single 24-hour specimen with StoneRisk Diagnostic Profile on a random diet before medication and treatment and updated the classification of nephrolithiasis. For specific subclassification of hypercalciuric calcium(Ca) nephrolithiasis, calcium and sodium restricted diet and sodium cellulose phosphate screening test were underwent. Abnormal urinary biochemistry was classified into one or more of 20 etiologic categories. A single diagnosis was documented in 37(34.6%) patients and the remaining 65.4% had more than one diagnosis. Hypercalciuric Ca nephrolithiasis occurred in 41 (38.3%) patients and specific subclassification of 6 variants was performed. In this study, hypercalciuric Ca nephrolithiasis occurred less frequently in comparison to the incidence of U.S.A. reported by Dr. Pak. Hyperuricosuric Ca nephrolithiasis (HUCN) and gouty diathesis(GD) accounted for 47(43.9%) and 8(7.4%) patients, respectively. Hyperoxaluric Ca nephrolithiasis was in 25(23.4%) patients and all were dietary origin following an oxalate-restricted diet. Hypocitraturic Ca nephrolithiasis was seen in 51(47.6%) patients in idiopathic variant. Hypocitraturia due to RTA and chronic diarrheal syndrome occurred in 1(0.9%) and 2(1.8%) patients. Hypomagnesiuric Ca nephrolithiasis and acquired problem of low urine volume(<1 L/d) were accounted in 3(2.8%) and 13(12.2%) patients, respectively. Infection stones or cystinuria were not detected. No metabolic abnormality was found in 12(11.2%) patients. High sodium take was detected in 60(56.1%) patients, reflecting that Koreans take high sodium containing foods. We think that StoneRisk Diagnostic Profile using a single 24-hour urine specimen is very useful in detecting stone-forming risk factors and providing specific therapeutic guidelines. Additionally, recurrence associated with high cost of medical care can be reduced through adequate diagnostic evaluation as part of the treatment regimen.
Biochemistry ; Calcium ; Cellulose ; Classification ; Cystinuria ; Diagnosis ; Diet ; Humans ; Incidence ; Korea* ; Mass Screening ; Nephrolithiasis* ; Outpatients ; Recurrence ; Risk Factors ; Sodium

Verrucous carcinoma of the larynx is a distinct and uncommon variant of well-differentiated squamous cell-carcinoma. The authors hybridized in situ a case of laryngeal verrucous carcinoma with DNA prebes to humman papillomavirus (HPV) 6, 11, 16, 18, 31, 33 and 35. The DNAs from the verrucous carcinoma of larynx hybridized with mixed DNA probes HPV-16/18 and 31/33/35. In addition, there was an evidence of HPV infection based on hybridization with mixed DNA probe HPV-6/11 in the adjacent papilloma tissue. By in situ DNA hybridization techniques, we clearly demonstrated human papillomavirus (HPV-16/18, and 31/33/35) related sequences in this neoplasm. These findings suggest the role of HPV-6/11 in the development of laryngeal papilloma ad HPV-16/18 and 31/33/35 probably on the progression to verrucous carcinoma.
Humans

Hemolytic disease of newborn due to Rhesus incompatibility occurs mostly by anti-Rh(D) antibodies. But recently, because of Rh(D) immune globuin prophylaxis, Rh(D) incompatibility is decreased and importance of minor group incompatibility is increasing. The majority of minor blood group incompatibilities are anti-c, anti-E or anti-Kell, but hemolytic diseases caused by combination of these antibodies are relatively rare. The 21 day-old male neonate was admitted because of pallor and poor feeding for 2 days. Laboratory data showed severe normochromic and normocytic anemia with increased reticulocyte and bilirubin. Patient's and his mothers blood type was B, Rh(D) positive. Minor blood groups of mother's and sons were different and anti-c and anti-E antibody were detected in mother's serum. After transfusions of two times with anti-c and anti-E free B, Rh(D) positive blood, the baby was discharged at 11th hospital day with good general condition.
Anemia ; Antibodies ; Bilirubin ; Blood Group Antigens ; Blood Group Incompatibility ; Erythroblastosis, Fetal ; Humans ; Infant, Newborn* ; Male ; Mothers ; Pallor ; Reticulocytes

The specific aim of the current study was to correlate the effects of partial outlet obstruction on the contractile responses of isolated strips of bladder smooth muscle to repetitive stimulation in the presence and absence of glucose. Adult male Sprague Dawley rats were subjected to partial outlet obstruction by the surgical placement of silk ligatures around the urethra. After two weeks, each rat was anesthetized and the bladder excised and isolated strip studies performed. After equilibration the strips were subjected to repetitive stimulations with FS, bethanechol, or KCI in the presence or absence of glucose. Both phasic and contractile responses were measured. The results are follows: 1. The maximal phasic response to FS was significantly decreased in the obstructed strips when compared to controls; no differences were noted for responses to bethanechol or KCI. 2. The tonic responses to all forms of stimulation were significantly decreased after obstruction; the tonic response to FS was decreased to a greater degree than were the tonic responses to bethanechol and KC1. 3. In the presence of glucose, the magnitude of phasic and tonic responses to bethanechol and KCl were well maintained in control strips during repetitive stimulation. 4. However, the phasic responses to FS were well maintained during repetitive stimulation whereas the tonic responses progressively decreased by approximately 60%. 5. In the absence of glucose, the tonic responses of control strips to all forms of stimulation were reduced to a greater degree than the phasic responses. 6. Partial outlet obstruction significantly reduced the phasic responses to FS, bethanechol, and KCI by 28.5%, 28.8% and 37.4% respectively and tonic response to FS was reduced to 28.6% of control value in glucose containing Tyrodes solution. Clinically significant reduction of bladder contraction is related to the reduction of glucose metabolism in obstructed bladder. Considering significant reduction of tonic response to FS, we think that neurotransmitter is major factor in contraction reduction in obstructed bladder.
Adult ; Animals ; Bethanechol ; Glucose* ; Humans ; Ligation ; Male ; Metabolism ; Muscle, Smooth ; Neurotransmitter Agents ; Rats* ; Rats, Sprague-Dawley ; Silk ; Urethra ; Urinary Bladder*

covered with liguid nitrozen and pulverized with a pestle. To the powered tissue 5ml of 3.3M formic acid/0.5% Tween 20 was added and centrifuged at 40,000*g for 10 min. An aliquot of supernate was put into C18 sepak minicolumn to eliminates IGF-BPs. Measurement of IGF-I in rat tissues was done by RIA with anti-hIGF-I antibody and hIGF-I(PSIII) standard which was prepared by Drs. L. E. Underwood and J. J. Van Wyk UNC at Chapel Hill, NC, USA and distributed through the National Hormone and Pituitary Distribution Program. Distribution of IGF-I in rat tissue was seen by SDS-PAGE and ligand blotting method. A cDNA library in lambda gt11 of rat liver was used to isolate the cDNA of IGF-I. Phage containing inserts encoding rat IGF-I were identified by hybridization with biotin labeled synthesized oligomer which was the sequence from 1 to 8 aminoacids of known rat IGF-I. The EcoRI inserts were subcloned into PBluescript SK. The nucleotide sequence of both strands was determined by the dideoxy chain termination method. RESULTS: 1)IGF-BPs in tissue extract which could compete with antibody for IGF-I in measureing the IGF-I were eluted at 50Kdalton molecular weight marker using Protein-pak 300SW column. Using C18-sepak minicolumn, IGF-BPs were completely eliminated from tissue extract as much as possible, using Protein-pak 300SW column. 2)The amount of IGF-I in tissues was as folows: liver 575+/-41.6ng/g, lung 552.0+/-40.8ng/g. kidney 503+/-30.8ng/g, heart 449.0+/-30.4ng/g, testis 225+/-18.8ng/g, spleen 146+/-26.4ng/g, muscle 92+/-7.6ng/g and brain 49.0+/-5.8ng/g. The amount of IGF-I in blood was 1403+/-60.8ng/ml. 3)Banding patterns of IGF-BPs in rat tissues extract were obtained using ligand blotting. IGF-BP3 bands at 50 Kdalton molecular weight marker were strongly shown in testis, heart, and lung extracts but not in brain and muscle. IGF-BP1 and 2 band at 30Kdalton molecular weight marker was strongly shown in liver, kidney, spleen, testis, heart and lung. IGF-BP4 band at 21 Kdalton molecular weight marker was weakly shown only in spleen and muscle. 4) The nucleotide sequence of cloned cDNA of rat IGF-I is as follows. 5 10 15 5'----- CC CTT TGC GGG GCT GAG CTG GTG GAC GCT CTT CAG TTC GTG TGT 20 25 30 -GGA CCA AGG GGC TTT TAC TTC AAC AAG CCC ACA GGC TAT GGC- 35 40 45 -TCC AGC ATT CGG AGG GCA CCA CAG ACG GGC ATT GTG GAT GAG------3 CONCLUSION: This study suggests that tissue extraction method for IGF-I from tissues and elimination of IGF-BPs using C18 sepak minicolumn is suitable for measuring in large numbers of samples. Expression of IGF-I and IGF-BPs in multiple tissues suggests some phsiologic function at each tissue level. Subcloning of cDNA of exon 3 and 4 of IGF-I was useful for studying regulation of IGF-IA and IB mRNA in rat tissue.
Animals ; Bacteriophages ; Base Sequence ; Biotin ; Brain ; Carrier Proteins* ; Clone Cells ; DNA, Complementary ; Electrophoresis, Polyacrylamide Gel ; Exons ; Gene Library ; Heart ; Insulin-Like Growth Factor I* ; Kidney ; Liver ; Lung ; Molecular Weight ; Polysorbates ; Rats* ; RNA, Messenger ; Spleen ; Testis