1.Diffuse Neonatal Hemangiomatosis.
Annals of Dermatology 2003;15(1):17-20
Diffuse neonatal hemangiomatosis (DNH) is a rare entity with the distinctive features of multiple hemangiomas of the skin and internal organs, which may result in a fatal outcome if wide-spread involvement of the internal organs. We report a case of DNH with cutaneous and hepatic involvement. The significant regression in the vascular lesions was achieved with systemic corticosteroid therapy.
Fatal Outcome
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Hemangioma
;
Skin
2.A caomparative study on therapeutic factors in in-patient and out-patient group psychotherapies.
Journal of Korean Neuropsychiatric Association 1991;30(1):178-187
No abstract available.
Humans
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Outpatients*
;
Psychotherapy*
3.A Case of C. R. S. T Syndrome.
Gong Myung HYUN ; Jin Tack KIM
Korean Journal of Dermatology 1976;14(3):227-231
Recently, a benign variant of scleroderma, called the C.R.S. T, syndrome, has ben ibed by Winterbauer. Patients with this disorder have skin changes such as Cermal and subr,utaneous calcinosis, Raynauds phenomenon, sclerodactyly, and te1angiectasia. With the passible exception. of the gastroirgestinal syaterh, involvernent of other organs is uncommon, and affected. individuals have a Iong clinical cgurse. A case of C.R.S.T. syndrome in 25-year-old femala in reported with brief reviev of literatures. The patient showed miultiple pea sized nodular depoaits on dermal and subcuta.neous layers of both elbow and. knee joints, Rayaauds phenamenon, sclerrodactyly with acroselerosis and sclerodermatous change on both hands and forearm and telangiectasia on face and both palms On eeophagogram, slight disturhance of passage at the cardioesophageal junetion area was noted.
Adult
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Calcinosis
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Elbow
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Forearm
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Hand
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Humans
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Knee Joint
;
Peas
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Skin
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Telangiectasis
4.Clinical observation in the aged surgical patients.
Journal of the Korean Surgical Society 1993;44(1):38-45
No abstract available.
Humans
5.A Case of Subungual Exostosis.
Gong Myung HYUN ; Jin Tack KIM
Korean Journal of Dermatology 1978;16(2):143-147
Subungual exostosis is a solitary fibrus nodule on the inner border of the terminal phalanx of the great toe. Rarely, the terminal phalanges of other toes, particularly the little toe, or even the fingers are involved. The first appearance is a small pinkish growth projecting slightly beyond the inner free edge of the nail, which pushes upward and backward. A case of Subungual exostosis affecting 20 year old man, who has been suffering from bean sized nolule on subungual area of terminal phalanx of left 5th toe. The skin iesion developed 1 year ago, and increased size insidiously and tendemess on pressure or tight shoes was noted. Diagnosis was confirmed by histopathologic and radiologic studies, and treated witb complete excision of tumor mass.
Diagnosis
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Exostoses*
;
Fingers
;
Humans
;
Shoes
;
Skin
;
Toes
;
Young Adult
6.A clinical study on the donor site pain from the ilium.
The Journal of the Korean Orthopaedic Association 1992;27(4):970-978
No abstract available.
Humans
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Ilium*
;
Tissue Donors*
7.The relationship between spondylolisthesis and the configuration of the laminas and facet joints.
The Journal of the Korean Orthopaedic Association 1992;27(5):1219-1228
No abstract available.
Spondylolisthesis*
;
Zygapophyseal Joint*
8.Comparison of Cinical Results between the Anterior Interbody Fusion and the Posterolateral Fusion with Transpedicular Fixation for the Treatment of Isthmic Spodylolisthesis in Adults.
The Journal of the Korean Orthopaedic Association 1997;32(1):16-29
The results of surgical treatment for isthmic spondylolisthesis in children and adolescent have been well documented. Successful clinical results with fusion can be expected in children and adolescent. But in adults, instability was not the only problem. In addition to their instability, adults were more likely to have degenerative disc changes and nerve compression not solved by fusion only. The role of decompression in the surgical treatment of adult isthmic spondylolisthesis remains controversial. Anterior interbody fusion could obtain indirect decompression of nerve root through widening of intervertebral space. Posterolateral fusion with transpedicular fixation could get direct decompression. So, the purpose of this study is to compare the clinical results of the anterior interbody fusion and the posterolateral fusion with transpedicular fixation for the treatment of isthmic spondylolisthesis in adults. We reviewed the clinical data of 40 adult patients who had been taken operation due to isthmic spondylolisthesis from June, 1977 to June, 1994. The anterior interbody fusion was performed in 20 patients (Group I) and the posterolateral fusion with transpedicular fixation was performed in 20 patients (Group II). The mean age of group I was 44.1 years old (21-62), and that of group II was 41.3 years old (21-57). The gender of patients was 8 males and 12 females in group I, and 5 males and 15 females in group II. The symptoms and signs of group I and II were similar. The duration of follow-up was average 3.6 years (1.1-16 years) in group I and average 2.3 years (1.1-6 years) in group II. The anterior slippage of group I by Taillard method was 16.1% and was corrected into 10.4% after opera-up was average 3.6 years (1.1-16 years) in group I and average 2.3 years (1.1-6 years) in group II. The anterior slippage of group I by Taillard method was 16.1% and was corrected into 10.4% after operation. That of group II was 15.2% and corrected into 9.8% after operation. The fusion rate at 12 months after operation was 90% in group I and 95% in group II. The clinical results were analysed by Kim's criteria that was focused on the improvement of clinical symptoms. The satisfactory results were obtainted in 85 % of group I and 90 % of group II. So there was no significant difference of clinical results between the anterior interbody fusion and the posterolateral fusion with transpedicular fixation for the treatment of isthmic spondylolisthesis in adults (p<0.05).
Adolescent
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Adult*
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Child
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Decompression
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Female
;
Follow-Up Studies
;
Humans
;
Male
;
Spondylolisthesis
9.Significance of Whole Body bone Scan in bone and Joint Tuberculosis
The Journal of the Korean Orthopaedic Association 1989;24(1):227-236
For confirmative diagnosis of bone and joint tuberculosis, it is made by culture method, inoculation to guinea pig, or histological examination of the specimen obtained from a lesion site. But plain reontgenogram is not valuable for early detection of the disease because specific, abnormal finding is not found in early stage and only found in late stage as progressive destruction of bone and joint. Many reports were made thst whole body bone scan, as diagnostic tool, was valuable in other orthopedic disease, but report for its diagnostic value in bone and joint tuberculosis is very rare. The study was carried out on 35 patients of bone and joint tuberculosis who whole body bone scan was performed before operation from Janusry, 1978 to December, 1987 in Depaartment of Orthopedic Surgery, Yonsei University college of Medicine. The following results were obtained. 1. Value of early detection of tuberculosis is not much as pyogenic infection. Intensity of uptake was decreased in tuberculosis than acute pyogenic osteomyelitis and arthritis, but increased than chronic osteomyelitis. 2. Intensity of uptake was decreased in female than male, and also increased in age. group under 10 and over 60 than other age group. 3. The longer duration of the disease, the more decreased intensity of uptake. 4. Intensity of uptake is increased in joint tuberculosis than bone, snd also increased in tuberculosis of spine than long bone. 5. Multifocal disease was detected in 14.3% by whole body bone scan.
Animals
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Arthritis
;
Diagnosis
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Female
;
Guinea Pigs
;
Humans
;
Joints
;
Male
;
Methods
;
Orthopedics
;
Osteomyelitis
;
Spine
;
Tuberculosis
;
Tuberculosis, Osteoarticular
10.Change of TypeI and TypeII Collagen Biosynthesis by Growth Factors in Cultured Cells Isolated from Rabbit Intervertebral Disc.
The Journal of the Korean Orthopaedic Association 1998;33(7):1867-1882
Growth factors influencing the function of chondrocytes are insulin-like growth factor I(IGF-I), basic fibroblast growth factor(bFGF), transforming growth factor-beta1(TGF-beta1), and epidermal growth factor(EGF). To find out the role of four kinds of growth factors in the biosynthesis of type I and II collagen represented as the phenotype of the disc cells, we cultured the disc cells isolated from rabbit intervertebral discs primarily and then checked cell proliferation, the expression of type I and II procollagen mRNA, and the immunohistochemical stains with type I and II collagen antibodies during in vitro culture in the maintenance medium containing low serum concentration with adding four kinds of growth factors. The results are as follows. FBS(10% Fetal bovine serum) group showed the highest cell proliferation potential. EGF and TGF groups showed remarkable cell proliferation, but there was no significant difference in IGF and FGF groups comparing to control group. A partial clone that encodes the rabbit type II procollagen C-propeptide region(RbCo12A1) was successfully isolated by reverse transcription-polymerase chain reaction using total RNA extracted from articular chondrocytes of rabbits. The identity of the cDNA clone was confirmed by DNA sequencing of the polymerase chain reaction products. A comparison of human al(II) cDNA sequence showed high sequence homology(83.6%). Type I procollagen mRNA expressed highly in EGF group. FGF, IGF, and TGF groups showed no significant expression comparing to control group. FBS group showed lower expression than control group. Type II procollagen expression was increased with passage of time, so at Day 10 it was the highest in all groups. Control group showed the highest expression among 6 experimental groups. The expression of type II procollagen in FGF and TGF groups was slightly lower than that of control. EGF and IGF groups showed markedly decreased expression comparing to control group. That in FBS group was the lowest, so it was three times lower than control group. In immunohistochemical stains with type I collagen, there was no difference among control, FBS, and EGF groups. FGF, IGF, and TGF groups showed increased positivity on stain comparing to control group, but the positivity didnt exceed 10%. For type II collagen, EGF and FGF groups showed decreased positivity, but there was no significant difference in FBS, IGF, and TGF groups comparing to control group. On the basis of this study, it may be concluded that TGF-pl showed the possibility of regeneration or delay the degeneration process of the intervertebral disc through the contribution to the stimulatory effects of cell proliferation and the synthesis of type II collagen. For the clinical use of this, more studies about the combination effects with FBS or other kinds of growth factors and finding out the ideal concentration about TGF-pl will be needed.
Antibodies
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Cell Proliferation
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Cells, Cultured*
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Chondrocytes
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Clone Cells
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Collagen Type I
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Collagen Type II
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Collagen*
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Coloring Agents
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DNA, Complementary
;
Epidermal Growth Factor
;
Fibroblasts
;
Humans
;
Intercellular Signaling Peptides and Proteins*
;
Intervertebral Disc*
;
Phenotype
;
Polymerase Chain Reaction
;
Procollagen
;
Rabbits
;
Regeneration
;
RNA
;
RNA, Messenger
;
Sequence Analysis, DNA