1.A Case of Nasolacrimal Duct Obstruction Caused by a Lacrimal Sac Retention Cyst
Seung Hyuck YANG ; Hahn Jin JUNG ; Young-Seok CHOI ; Woo Sub SHIM
Journal of Rhinology 2024;31(1):42-45
Acquired nasolacrimal duct obstruction may result from chronic infection, lacrimal stones, anatomical variations such as aberrant ethmoid cells, facial fractures, or complications following nasal surgery. In Korea, there has been no reported case of secondary nasolacrimal duct obstruction due to a retention cyst in the lacrimal sac. Recently, the authors encountered a 65-year-old female patient who presented with epiphora, was diagnosed with a lacrimal sac retention cyst, and was successfully treated with endoscopic marsupialization.
2.Maternal and perinatal outcomes in triplet versus twin pregnancies with the result of Assisted Reproductive Technology.
Chang Ik CHOI ; In Bai CHUNG ; Gab Young OH ; Ki Dong CHOI ; Hyun Il CHOI ; Hyuck Dong HAN ; Young Jin LEE
Korean Journal of Obstetrics and Gynecology 1999;42(9):2013-2018
The present study was performed to compare maternal and perinatal outcomes in triplet and twin pregnancies with the result of ART(Assisted Reproductive Technology). Each pregnancy of 18 triplet pregnancies with 18 weeks or more was matched for maternal age, EDC(estimated date of confinement), parity, history of preterm delivery, indication of ART with two sets of twin pregnancies. Triplet pregnancies had a significantly shorter gestational age at delivery than twin pregnancies(30.4 versus 34.6 weeks), and a significantly lower mean birth weight(1,514 versus 2,286g). The mean hospital stay was significantly longer in triplets(22.3 versus 10.1 days). The incidences of 5 min Apgar score less than 7, neonatal deaths were significantly more often in triplets than twins; 18(33.3%) vs 6(8.3%), 15(27.8%) vs 7(9.72%), respectively. There were significant differences in the incidence of neonatal complications such as respiratory distress syndrome; 14(25.9%) vs 7(9.72%), ventilatory support; 18(33.3%) vs 5(6.9%), neonatal seizure; 9(16.7%) vs 0, btween the two groups. However, there were no significant differences between the groups in maternal complications or neonatal morbidity such as congenital malformations or hyperbilirubinemia, intraventricular hemorrhage, or bronchopulmonary dysplasia. We suggest that counseling patient regarding the anticipated perinatal outcomes of triplet pregnancies with the result of ART should be conducted with our data.
Apgar Score
;
Bronchopulmonary Dysplasia
;
Counseling
;
Female
;
Gestational Age
;
Hemorrhage
;
Humans
;
Hyperbilirubinemia
;
Incidence
;
Infant, Newborn
;
Length of Stay
;
Maternal Age
;
Parity
;
Parturition
;
Pregnancy
;
Pregnancy, Triplet
;
Pregnancy, Twin*
;
Reproductive Techniques, Assisted*
;
Seizures
;
Triplets*
3.Clinical Features of Late-Onset Sepsis with Fatal Outcome in Early Phase of Infection in Neonatal Intensive Care Unit Patients and Impact of Initial Antibiotic Therapy.
Jin Hyuck CHOI ; Chun Soo KIM ; Sang Lak LEE
Korean Journal of Perinatology 2011;22(4):329-336
PURPOSE: Late-onset sepsis (LOS) is a serious problem in the neonatal intensive care unit (NICU). This study was undertaken to investigate clinical features of LOS (occurring after 72 hours of age) with fatal outcome (lethal within 72 hours of onset) in early phase of infection in NICU patients and impact of initial antibiotic therapy. METHODS: Retrospective analysis of the medical records was conducted to find LOS in patients in a NICU of university hospital over an 8-year period (2001-2008). RESULTS: There were 455 episodes of blood culture-proven LOS in 388 (6.9%) of 5,608 infants who survived beyond 3 days of age. Gram-positive bacteria were the most common pathogen, accounting for 265 cases (58.2%), and were followed by fungi with 101 cases (22.2%) and Gram-negative bacteria with 89 cases (19.6%). Fatal outcome in early phase of infection occurred in 14 cases (3.1%), and the most prevalent organism of fatal infection was Klebsiella, accounting for 7 cases (50%). Both Candida and S. aureus caused 2 cases of sepsis with fatal outcome, and also Acinetobacter, E. coli and Enterococcus caused 1 case respectively. The fatal outcome was more frequently developed in patients with Gram-negative sepsis than those with Gram-positive or fungal infections (10.1% vs. 2.0% vs. 1.1%; P <0.05). In clinical findings of patients with fatal outcome, the median of age at onset of infection was 19 days (range: 6-94 days), and the interval between onset and death was 29 hours (range: 10-58 hours). Severe sepsis at onset of infection was developed in 7 cases (50.0%), and the use of adequate empirical antibiotics was done in 10 cases (71.4%) of them. CONCLUSION: LOS by Gram-negative bacteria may easily complicate with fatal outcome in neonates. It cannot be prevented with adequate empirical antibiotic therapy, and additional countermeasures against fatal infection are necessary in NICU.
Accounting
;
Acinetobacter
;
Anti-Bacterial Agents
;
Candida
;
Enterococcus
;
Fatal Outcome
;
Fungi
;
Gram-Negative Bacteria
;
Gram-Positive Bacteria
;
Humans
;
Infant
;
Infant, Newborn
;
Intensive Care, Neonatal
;
Klebsiella
;
Medical Records
;
Retrospective Studies
;
Sepsis
4.The status of assisted reproductive technology in Korea in 2012.
Gyoung Hoon LEE ; Hyun Jin SONG ; Young Min CHOI ; Hyuck Dong HAN
Clinical and Experimental Reproductive Medicine 2017;44(1):47-51
OBJECTIVE: This study was designed to report the status of assisted reproductive technology (ART) therapy in South Korea between January 1, 2012 and December 31, 2012. METHODS: A localized online survey, originally developed by the International Committee Monitoring Assisted Reproductive Technologies, was first launched and provided to all available ART centers via email in 2015. Fresh embryo transfer (FET) cases were categorized as standard in vitro fertilization, intracytoplasmic sperm injection (ICSI), or half-ICSI. Thawed embryo transfer (TET) and other related procedures, including surgical sperm retrieval, were surveyed. RESULTS: Data from 33,956 ovum pick-up procedures were provided by 75 clinics in 2012. Of the 33,088 cycles in which ovums were retrieved, a complete transfer was performed in 90.5% (29,932 cycles). In addition, 10,079 FET cycles were confirmed to have resulted in clinical pregnancy, representing a pregnancy rate of 30.5% per ovum pick-up and 33.7% per ET. The most common number of embryos transferred in FET was 2 (41.6%), followed by 3 (34.0%), and non-elective single ETs (10.0%). Of the 10,404 TET cycles in which transfer was completed, 3,760 clinical pregnancies (36.1%) were confirmed by ultrasonography. CONCLUSION: The overall clinical pregnancy rate for FET and TET cycles in 2012 was higher than in 2011 (33.7% vs. 33.2% and 36.1% vs. 31.1%, respectively). The most common number of embryos transferred in FET cycles was 2, unlike in 2011.
Electronic Mail
;
Embryo Transfer
;
Embryonic Structures
;
Fertilization in Vitro
;
Korea*
;
Ovum
;
Pregnancy
;
Pregnancy Rate
;
Reproductive Techniques, Assisted*
;
Sperm Injections, Intracytoplasmic
;
Sperm Retrieval
;
Ultrasonography
5.Orthopedic Injuries among Elite Adult Ice Hockey Players in Korea:A Self-Reported Questionnaire-Based Study
Donghee KWAK ; Jae Joong KIM ; Woong Kyo JEONG ; Jin Hyuck LEE ; In Cheul CHOI
The Korean Journal of Sports Medicine 2023;41(3):130-137
Purpose:
Epidemiological data on injuries resulting from ice hockey and their management are lacking in Korea. A comprehensive analysis of such data is crucial for the effective prevention and management of ice hockey injuries. This study aimed to determine the epidemiological profile of ice hockey injuries and their management among elite Korean players.
Methods:
The descriptive epidemiological study involved three semiprofessional male ice hockey teams and used a retrospective self-reported questionnaire for assessment. The data collected included demographic characteristics such as player positions and stick-side preferences, injured body parts, injury types, treatment methods, and the decision-maker for returning to sports.
Results:
A total of 68 players were included in the study, of whom 58 (85.3%) experienced moderate-to-severe orthopedic injuries. Among the reported injuries, 93 (77.5%) occurred during the games, with player-to-player contact being the most frequent cause of such injuries. The decision to return to sports in 53 cases (44.2%) was made by the medical staff, whereas players and nonmedical staff made that decision in 67 cases (55.8%). The decision-making process of the medical staff for allowing players to return to sports was significantly associated with the player’s position and whether the injury required surgery.
Conclusion
The study emphasizes the high prevalence of orthopedic injuries among elite ice hockey players in Korea and the importance of injury prevention strategies. It also highlights the need for increased involvement of medical staff in return-to-play decisions to ensure successful recovery of players and their reintegration into the competition.
6.Expression of c-erbB-2 and Cyclooxygenase-2 in Pancreatic Ductal Adenocarcinoma.
Hye Jeong CHOI ; Hong Jin KIM ; Sung Soo YUN ; Joon Hyuck CHOI
Korean Journal of Pathology 2007;41(3):171-175
Background : Carcinoma of the pancreas is a fatal malignant disease with limited therapeutic options. Cyclooxygenase-2 (COX-2) and c-erbB-2 are known to be involved in the carcinogenesis, differentiation and invasiveness of various neoplasms. We studied the immunohistochemical expressions of c-erbB-2 and COX-2 and the correlation between these expressions and the clinicopathologic parameters and the relation between the expressions. Methods : Immunohistochemical staining for c-erbB-2 and COX-2 were performed on the paraffin embedded sections of 36 cases of surgically resected ductal adenocarcinoma of the pancreas and 10 cases of non-neoplastic pancreas tissue. Results : The non-neoplastic control group showed a c-erbB-2 expression in the acini (8/10) and ducts (2/10), and a COX-2 expression in the acini (6/10) and ducts (3/10). The overexpression of c-erbB-2 was observed in 58% (21/36) of the carcinoma specimens. No significant correlation was found between c-erbB-2 and age, gender, tumor size, gross type, histologic grade, vascular invasion, perineural invasion, lymph node metastasis, and the TNM stage. The overexpression of COX-2 was observed in 41.7% (15/36) of the carcinoma specimens. The COX-2 expression was significantly high in the lymph node metastasis group (p<0.05), but it was not correlated with the other clinicopathologic parameters. Also there was no significant correlation between the c-erbB-2 and COX-2 expressions. Conclusions : In pancreatic ductal adenocarcinomas, c-erbB-2 and COX-2 were frequently overexpressed, and COX-2 overexpression was correlated with lymph node metastasis.
Adenocarcinoma*
;
Carcinogenesis
;
Cyclooxygenase 2*
;
Immunohistochemistry
;
Lymph Nodes
;
Neoplasm Metastasis
;
Pancreas
;
Pancreatic Ducts*
;
Paraffin
;
Receptor, erbB-2
7.Detection of Y Chromosome Microdeletion is Valuable in the Treatment of Patients With Nonobstructive Azoospermia and Oligoasthenoteratozoospermia: Sperm Retrieval Rate and Birth Rate.
Don Kyung CHOI ; In Hyuck GONG ; Jin Ho HWANG ; Jong Jin OH ; Jae Yup HONG
Korean Journal of Urology 2013;54(2):111-116
PURPOSE: We evaluated clinical characteristics, sperm retrieval rates, and birth rates in a relatively large number of infertile patients with Y chromosome microdeletions. MATERIALS AND METHODS: We retrospectively reviewed clinical data from 213 patients with nonobstructive azoospermia (NOA) and 76 patients with oligoasthenoteratozoospermia (OATS) who were tested for Y chromosome microdeletion from March 2004 to June 2011. RESULTS: Of the 289 patients, 110 patients presented with Y chromosome microdeletion and 179 patients presented with no microdeletion. Among the patients with Y chromosome microdeletions, 83/110 (75.4%) were NOA patients and 27/110 (24.5%) were OATS patients. After subdividing the patients with Y chromosome microdeletion, 29 had azoospermia factor (AZF)b-c microdeletion and 81 had AZFc microdeletion. The sperm retrieval rate was similar between patients with Y chromosome microdeletion and those with no microdeletion (26.6% vs. 25.6%, p=0.298) after multiple testicular sperm extraction (TESE). Excluding 53 patients who did not undergo TESE, 30 patients were analyzed. All of the 9 men with AZFb-c microdeletion had a complete absence of sperm despite multiple TESE. However, multiple TESE was successful for 9 of 21 patients with only AZFc microdeletion (p=0.041). Twenty patients with Y chromosome microdeletion gave birth. CONCLUSIONS: In NOA and OATS patients, no significant difference in the sperm retrieval rate was shown between patients with Y chromosome microdeletion and those with no microdeletion. Patients with short Y chromosome microdeletion such as AZFc microdeletion have better prognoses for sperm retrieval and an increased chance of conception than do patients with larger microdeletions such as AZFb-c microdeletion.
Avena
;
Azoospermia
;
Birth Rate
;
Chromosome Deletion
;
Chromosomes, Human, Y
;
Fertilization
;
Humans
;
Infertility, Male
;
Male
;
Parturition
;
Prognosis
;
Reproductive Techniques, Assisted
;
Retrospective Studies
;
Sex Chromosome Aberrations
;
Sex Chromosome Disorders of Sex Development
;
Sperm Retrieval
;
Spermatozoa
;
Y Chromosome
8.Various Pulmonary Manifestations of the Cryptococcal Pneumoniae in the three Immunocompetent Patients.
Jin Chan PARK ; Hyung Tae KIM ; Hun JEUNG ; Ji Han PARK ; Jae Hyuck CHOI ; Hyeon Tae KIM ; Jae Min PARK ; Yong Hee LEE ; Jeung Sook KIM
Tuberculosis and Respiratory Diseases 2001;50(3):359-366
More than half of the cryptococcal infections occur in acquired immune deficiency (AIDS) patients, and more than half of the non-AIDS patients with cryptococcosis are immunocompromised. Most immunocompromised patients have meningoencephalitis at the time of diagnosis. Without the appropriate therapy, this from of the infection is invariably fatal. Death can occur any time from 2 weeks to several years after the onset of symptoms. Pulmonary crytococcosis in immunocompromised patients is usually asymptomatic, but coughing, chest pain, fever, or hemoptysis may occur in immunocompetent patients. Pulmonary cryptococcosis symptoms in immunocompetent patients tend to improve without treatment. Here, we describe the various pulmonary manifestations of cryptococcal pneumoniae in three immunocmpetent patients.
Chest Pain
;
Cough
;
Cryptococcosis
;
Diagnosis
;
Fever
;
Hemoptysis
;
Humans
;
Immunocompromised Host
;
Meningoencephalitis
;
Pneumonia*
9.Anterior Spinal Artery Syndrome Associated With Cervical Spinal Stenosis.
Jong Ho PARK ; Ki Ran KWON ; Byung Chul LEE ; Suk Beom KWON ; Hwi Chul CHOI ; Jin Hyuck KIM
Journal of the Korean Geriatrics Society 1997;1(2):155-160
BACKGROUND: The anterior spinal artery infarction constitutes a classical syndrome of vascular myelopathy. The causes of the anterior spinal artery syndrome are various, but most episode probably occur as the result of atherosclerosis or dissection of the aorta and its branches. However, few cases reported developed with spinal structural abnormalities. CASE: A 65-year-old man presented with sudden paraparesis. There was no evidence of hypertension, diabetes and smoking. Motor weakness was more prominent on the left side and progressed. Loss of pain and temperature senses were shown at the level of 71 with preservation of touch, joint perception and vibration senses. The DTR's of legs were depressed and extensor toe signs were presented. A C-spine MRI showed high signal intensity on 72 weighted image and low signal on 71 weighted image(C6-71) with cervical spinal stenosis at the C4-C7 spinal level and mild cervical disc protrusion (C6-C7, C7-T1). After three months later, follow up cervical MRI showed somewhat decreased size of high signal intensity on 72 weighted image and more prominent low signal on 71 image. DISCUSSION: In our case, we could not find any usual cause of anterior spinal artery infarction. However only cervical spinal stenosis associated with mild cervical disc protrusion was present. In stenotic cervical canal, the anterior spinal artery can be more vulnerable to extrinsic compression and the infarction may early develop with insignificant trigger event, such as disc protrusion. We concluded that the ischemic change of anterior two thirds of cervical spinal cord might develop due to the compression of the anterior spinal artery by cervical stenosis and mild cervical intervertebral disc protrusion.
Aged
;
Anterior Spinal Artery Syndrome*
;
Aorta
;
Arteries
;
Atherosclerosis
;
Constriction, Pathologic
;
Follow-Up Studies
;
Humans
;
Hypertension
;
Infarction
;
Intervertebral Disc
;
Joints
;
Leg
;
Magnetic Resonance Imaging
;
Paraparesis
;
Smoke
;
Smoking
;
Spinal Cord
;
Spinal Cord Diseases
;
Spinal Stenosis*
;
Toes
;
Vibration
10.Middle East Respiratory Syndrome-Coronavirus Infection: A Case Report of Serial Computed Tomographic Findings in a Young Male Patient.
Won Jin CHOI ; Ki Nam LEE ; Eun Ju KANG ; Hyuck LEE
Korean Journal of Radiology 2016;17(1):166-170
Radiologic findings of Middle East respiratory syndrome (MERS), a novel coronavirus infection, have been rarely reported. We report a 30-year-old male presented with fever, abdominal pain, and diarrhea, who was diagnosed with MERS. A chest computed tomographic scan revealed rapidly developed multifocal nodular consolidations with ground-glass opacity halo and mixed consolidation, mainly in the dependent and peripheral areas. After treatment, follow-up imaging showed that these abnormalities markedly decreased but fibrotic changes developed.
Adult
;
Coronavirus Infections/pathology/*radiography
;
Fever/virology
;
Fibrosis
;
Humans
;
Male
;
*Middle East Respiratory Syndrome Coronavirus
;
Radiography, Thoracic/*methods
;
Republic of Korea
;
Tomography, X-Ray Computed/*methods