There is a wide array of designation for cutaneous vascular disorders based on clinical characteristics, histology, embryology, cellular biology, and hemodynamics. The cutaneous vascular disorders can be divided into hemangioma and vascular malformation according to the biologic classification based on cell kinetics i.e. endothelial hyperplasia. There are clinical and histologic differences between them. In this study, clinical, histologic and im-munohistochemical evaluations were attempted on 40 cases of cutaneous vascular disorders diagnosed the period between 1985 and 1993. The results are as follows: 1) Twenty-three out of forty cases were immunoreacive for proliferating cell nuclear antigen(PCNA). The lesions composed of capillary-sized blood vessels with endothelial hyperplasia were diffusely reactive, whereas those composed largely of dilated blood vessels with or without focal endothelial hyperplasia were only focally reactive. 2) Each groups of the classic classification contained both reactive and nonreactive cases except nevus flammeus and juvenfle hemangioma. 3) In contrast to the cases nonreactive for PCNA, those reactive for PCNA contained areas of proliferating small vessels, which showed reactivity for PCNA. In conclusion, the cutaneous vascular disorders diagnosed by the classic classification are heterogeneous in the pattern of the endothelial hyperplasia and the PCNA staining. Therefore it should be classified by the clinical and the histologic characteristics.
Hemangioma

PURPOSE: The purpose of this study was to develop a Cardiovascular Disease Resilience (CDR) scale to evaluate disease specific resilience for recovery. METHODS: The study was conducted as follows: items generation, and test of validity and reliability. Items were developed via literature review, review of instruments, and data acquired from the interviews. In order to test validity and reliability, seven panels of experts reviewed the preliminary questionnaire and then data were collected from 550 cardiovascular disease patients. Factor analysis, Pearson correlation, ANOVA, and Cronbach's alpha were used to analyze the data. RESULTS: In the preliminary stage, forty-four items were generated. A reduction to 40 items was accomplished through content validity analysis. Factor analysis extracted 7 factors with a total of 25 items. The CDR items were moderately correlated with the subscales of the CD-RISC (Connor-Davidson Resilience Scale) and the mean score of CDR was associated with quality of life measured with CD-QOL (Cardiovascular Disease Quality of Life). Cronbach's alpha=.84. CONCLUSION: Content validity, construct validity, criterion validity, and reliability of the CDR were established. The CDR is a reliable and valid instrument which the resilience of cardiovascular disease specific recovery state can be evaluated.
Cardiovascular Diseases ; Deoxycytidine ; Humans ; Quality of Life ; Reproducibility of Results

Intracranial lipomas located in the cerebellopontine angle are extremely rare. These tumors are maldevelopmental lesions which can cause slowly progessive neurological symptoms. The clinical management of these tumours differs significantly from other lesions in this region. A 45 year old man presented with a 3-month history of vertigo and tinnitus in the left ear. In T1-weighted magnetic resonance imaging, the lesion was hyperintense and did not enhance after application of gadolinium. The patient was treated with medical therapy with good response. We present a review of the literature, with particular regard to management. Conservative treatment is recommended and limited surgery is usually indicated if the patients suffer from disabling neurological symptoms and signs e.g., vertigo, nausea, trigeminal neuralgia, facial weakness or facial spasm.
Cerebellopontine Angle ; Ear ; Gadolinium ; Humans ; Lipoma* ; Magnetic Resonance Imaging ; Middle Aged ; Nausea ; Spasm ; Tinnitus ; Trigeminal Neuralgia ; Vertigo

PURPOSE: This study was to investigate the factors influencing quality of life of middle-aged women in rural area, to provide the basic data for health promoting intervention in order to improve quality of life. METHOD: The subjects were 469 middle-aged women by 40-64 from 7 rural areas in Gyeonggi-do, Jeolla-do and Gyeongsang-do. Data collection was conducted by using 6 questionnaires. RESULT: There were significant differences in the quality of life by age, educational level, marital status, religion, family pattern, and economic level. There were positive relationships between quality of life and health perception, social support, and negative relationships between quality of life and depression and stress. Stepwise Multiple Regression Analysis for quality of life revealed that the most powerful predictor was depression. Depression, health perception, social support, stress and economic level explained 51.5% of the variance. CONCLUSION: Depression, health perception, social support, stress and economic level were related with quality of life of middle-aged women in rural area. Therefore, it is necessary to develop the nursing intervention these psycho-social aspects to increase the quality of life.
Data Collection ; Depression ; Female ; Gyeonggi-do ; Humans ; Marital Status ; Methods ; Nursing ; Quality of Life* ; Rural Health ; Social Perception

PURPOSE: The purpose of this study was to explore the differences of health locus of control and treatment compliance according to general characteristics and severity in acute coronary syndrome(ACS) patients after percutaneous coronary intervention. METHODS: This descriptive study was conducted with a convenient sample of 103 ACS patients. The dependent variables were measured by the scales for the Multidimensional Health Locus of Control and the Treatment Compliance. The collected data were analyzed by the Fisher's exact test, Chi-square and t-tests, and ANOVA using the SPSS/WIN program. RESULTS: Pre-interventional severity was significantly different between men and women. In terms of internal health locus of control, there was a significant difference according to gender, educational status, economic status, and severity. The level of medication compliance was the lowest among the sub-scales of treatment compliance. CONCLUSION: These findings suggest that clinical nurses should evaluate the general characteristics and severity of the patients with ACS for providing tailored nursing interventions.
Acute Coronary Syndrome ; Compliance ; Educational Status ; Female ; Humans ; Internal-External Control ; Male ; Medication Adherence ; Percutaneous Coronary Intervention ; Weights and Measures

PURPOSE: The purposes of this study were as follows; 1) To review the definitions of critical thinking from various perspectives, 2) To examine the critical thinking measurements throughout nursing research, and 3) To review the nursing studies with regard to critical thinking. METHODS: This study was a literature review with regard to the critical thinking in nursing in aspects of conceptual meaning, measurements, and research. RESULTS: The definition of critical thinking in nursing included decision making in clinical setting, inference with logical construct to increase nursing quality, interpretation in the context, and evaluation. The critical thinking was a core concept, which meant not only simple nursing process, but included decision making ability. The critical thinking has been conceptualized by both critical thinking disposition and skill. However, there was no nursing specified critical thinking measurement. Critical thinking research has been conducted to describe critical thinking disposition and critical thinking, to determine relationships between critical thinking and clinical competency, and to evaluate the effectiveness of educational programs. CONCLUSION: The instruments for measuring critical thinking disposition and skill that contain cultural difference and clinical specificity need to be developed to measure critical thinking and increase it.
Decision Making ; Logic ; Nursing Process ; Nursing Research ; Sensitivity and Specificity ; Thinking

Pro-oxidant properties of ascorbate have been studied with uses of brain tissues and neuronal cells. Here we address potential mechanism of ascorbate coupling with glutamate to generate oxidative stress, and the role which oxidized ascorbate (dehydroascorbate) transport plays in oxidative neuronal injury. Ascorbate in neurones can be depleted by adding glutamate in culture medium since endogenous ascorbate can be exchanged with glutamate, which enhances ascorbate/ dehydroascorbate transport by depleting ascorbate in the neurons with the glutamate-heteroexchange. However, ascorbate is known readily being oxidized to dehydroascorbate in the medium. Glutamate enhanced the dehydroascorbate uptake by cells via a glucose transporter (GLUT) from extracellular region, and cytosolic dehydroascorbate enhanced lipid peroxide production and reduced glutathione (GSH) concentrations. Iso-ascorbate, the epimer of ascorbate was ineffective in generating the oxidative stress. These observations support the current concept that the high rates of dehydroascorbate transport via a GLUT after the release of ascorbate by glutamate leads to peroxidation, the role of glutamate on ascorbate/ dehydroascorbate recycling being critical to induce neuronal death via an oxidative stress in the brain injury.
Animals ; Ascorbic Acid/analogs & derivatives/pharmacology ; Biological Transport/drug effects ; Cerebral Cortex/*drug effects/*metabolism ; Cytochalasin B/pharmacology ; Dehydroascorbic Acid/*metabolism ; Glutamic Acid/*pharmacology ; Glutathione/metabolism ; In Vitro ; Lipid Peroxidation/*drug effects ; Male ; Oxidation-Reduction/drug effects ; Oxidative Stress/drug effects ; Rats ; Rats, Sprague-Dawley ; Thiobarbituric Acid Reactive Substances/metabolism

PURPOSE: The purpose of this study was to discover the recovery process of those having had myocardial infarction. METHODS: 15 participants with myocardial infarction were recruited by theoretical sampling methods. The data were retrieved through in depth interview, participant observation, and medical records of the patients. Collected data were analyzed through grounded theory approach of Strauss and Corbin(1998). RESULTS: 63 concepts, 27 subcategories, and 11 categories were deduced from the open coding process. The recovery process of myocardial infarction showed to be a process of 'Controling healthy track', and chronological recovery process was a four-step process of recognizing disruption of healthy track, making efforts for controlling the disrupted healthy track, reconstructing the new healthy track, and adapting to the new healthy track phase. 'Controling healthy track' had three types of self-initiation, contention of reality, and fateful acceptance. CONCLUSION: The results provided basic information for nursing intervention strategies depending on 'Controling healthy track' process by each phase and different types.
Clinical Coding ; Humans ; Medical Records ; Myocardial Infarction ; Track and Field

PURPOSE: The purpose of this study was to discover the recovery process of those having had myocardial infarction. METHODS: 15 participants with myocardial infarction were recruited by theoretical sampling methods. The data were retrieved through in depth interview, participant observation, and medical records of the patients. Collected data were analyzed through grounded theory approach of Strauss and Corbin(1998). RESULTS: 63 concepts, 27 subcategories, and 11 categories were deduced from the open coding process. The recovery process of myocardial infarction showed to be a process of 'Controling healthy track', and chronological recovery process was a four-step process of recognizing disruption of healthy track, making efforts for controlling the disrupted healthy track, reconstructing the new healthy track, and adapting to the new healthy track phase. 'Controling healthy track' had three types of self-initiation, contention of reality, and fateful acceptance. CONCLUSION: The results provided basic information for nursing intervention strategies depending on 'Controling healthy track' process by each phase and different types.
Clinical Coding ; Humans ; Medical Records ; Myocardial Infarction ; Track and Field

PURPOSE: The purpose of this study were to describe the level of activities of daily living (ADLs) and fatigue of stroke patients and to identify related factors of ADLs and fatigue. METHOD: A sample of 132 were used who were recovering from stroke. The face-to-face interviews were conducted to collect data. The levels of ADLs and fatigue were evaluated using the Modified Barthel Index and Kim's fatigue scale respectively. A series of t-test and analysis of variance analyses were conducted to examine study purposes using SPSS 15.0. RESULTS: The levels of fatigue and ADLs were 65.6 (SD=16.52) and 74.6 (SD=22.32) respectively. Significantly poorer ADLs were found: women (t=2.05, p=.001), older people aged > or = 70 years (F=2.74, p=.046), the duration of onset (F=4.32, p=.006), the use of assist devices (F=35.64, p<.001), the parts of paralysis (F=4.25, p=.007), the time to attack (F=3.34, p=.039), and accompanying symptoms (F=15.23, p<.001). There was a significant difference in fatigue with patients with lower accompanying symptoms having lower fatigue (F=11.08, p<.001). CONCLUSION: These findings suggest gender, the duration from onset, the use of assist device, the parts of paralysis, the time to attack and accompanying symptoms were significant factors of the ADLs and fatigue post stroke. These factors should be considered when developing and testing nursing intervention programs for stroke survivors.
Activities of Daily Living ; Aged ; Fatigue ; Female ; Humans ; Paralysis ; Stroke ; Survivors