Background: This study was aimed to compare the analgesic effect and side effects of morphine- bupivacaine mixture with those of fentanyl-bupivacaine mixture after Cesarean section. Methods: Eighty patients who were taken continuous epidural catheterization after Cesarean section were divided into two groups. In group 1 (N=40) the mixture of 1% lidocaine 10 ml and morphine 1mg was firstly injected via epidural catheter, and then two day infusor (Baxter(R)) which contained the mixture of 0.15% bupivacaine 100 ml and morphine 6mg was connected to epidural catheter. In group 2 (N=40) the mixture of 1% lidocaine 10 ml and fentanyl 100 mcg was firstly injected via epidural catheter, and then two day infusor (Baxter(R)) which contained the mixture of 0.15% bupivacaine 100 ml and fentanyl 850 mcg was connected to epidural catheter. Mean arterial pressure (MAP) and heart rate (HR) were checked preoperatively, and at post-injection 10, 20, 30 and 60 minutes. The visual analogue scale (VAS) was checked at postoperative 1/2, 1, 6, 12, 24 and 48 hours. The side effects of epidural analgesia were evaluated. Results: In group 2 MAP was significantly decreased at post-injection 20 minute. VAS was significantly increased at post-injection 1/2 and 1 hour in group 1. The most frequent side effect was pruritus in both groups. Conclusions: The first bolus injection of the mixture of 1% lidocaine 10 ml and fentanyl 100 mcg has more rapid analgegic effect than the mixture of 1% lidocaine 10 ml and morphine 2 mg, but because of shorter duration of action of fentanyl it seems to be better to increase the dosage of fentanyl or replace fentanyl by morphine for more effective epidural analgesia after Cesarean section.
Analgesia, Epidural ; Arterial Pressure ; Bupivacaine ; Catheterization ; Catheters ; Cesarean Section* ; Female ; Fentanyl ; Heart Rate ; Humans ; Infusion Pumps ; Lidocaine ; Morphine ; Pregnancy ; Pruritus

No abstract available.
Epidemiologic Studies* ; Female* ; Humans ; Temporomandibular Joint Disorders* ; Young Adult*

BACKGROUND: Plant extracts have been widely used as important therapeutic drugs for many centuries all over the world. There have been many reports that natural products have various kinds of biological activities such as anti-allergy, anti-inflammatory and antimicrobial activities. Recently, the screening for the efficacy and safety of natural products has been extensively performed. OBJECTIVE: This study was carried out to find a beneficial plant extract possessing excellent antioxidative and anti-melanogenic activities. We have found that the leaf of Robinia pseudo-acacia L. has active substances which are involved in those activities. METHODS: To confirm the antioxidative activity of the extract obtained from the leaves of Robinia pseudo-acacia L., scavenging ability of the extract on DPPH free radicals and its inhibitory effects on lipid autoxidation and peroxidation were investigated. In addition, inhibitory effects of the extract on mushroom tyrosinase as well as melanin biosynthesis in cultured B16 melanoma cells were evaluated. RESULTS: The acacia extract showed not only powerful antioxidative activity but also antimelanogenic acitivity as strong as that of arbutin which is a well known inhibitor of melanogenesis. CONCLUSION: These resulis suggest that the extract from the leaves of Robinia pseudo-acacia L. could be used as a 4ghtening and antioxidative agent for the skin.
Acacia ; Agaricales ; Arbutin ; Biological Products ; Free Radicals ; Mass Screening ; Melanins ; Melanoma, Experimental ; Monophenol Monooxygenase ; Plant Extracts ; Plants ; Robinia* ; Skin

No abstract available.
Anesthesia* ; Mediastinal Emphysema*

CT was proved to be the most accurate diagnostic tool in the analysis of brain metastasis than any otherclassical methods. The authors studied CT findings of intracranial metastasis in 31 cases proven clinically andhistologically. The results were as follows; 1. Age distribution of the cases was 15 males and 16 females withpeak age of 6th decade in males and 4th decade in females. 2. Metastatic lesions were multiple in 18 cases andsingle in 13 cases. 3. The most common degree of edema was grade III, 43% of total metastatic foci. Markededematous low densities with relatively small nodular high densities in precontrast scan and variable contrastenhancement of the nodular densities were the most frequent CT findings. 4. No specific characterstics accordingto the primary cancer was noted. All four cases of choriocarcinoma showed hemorrhagic tendency.
Age Distribution ; Brain ; Choriocarcinoma ; Edema ; Female ; Humans ; Male ; Neoplasm Metastasis ; Pregnancy

Partial unilateral lentiginosis(PUL) is a rare pigmentary disorder charaeterized by lentigines limited to one side of the body with or without neurologic abnormalities. We report two cases of PUL unassociated with any other defect, One patient was 20-year-old female who had lentigines confined to the right side of the face and the other was 19-year-old male who had lentigines confined to the left side of the neck and upper trunk and left upper extremity. Histologic examination of the pigmented lesion revealed findings consistent with lentigo simplex.
Female ; Humans ; Lentigo* ; Male ; Neck ; Upper Extremity ; Young Adult

A clinical analysis on the 33 cases of the collateral ligament injuries of the knee joint was made. Those cases were classified in three groups depend upon the width of the joint space by means of stress-radiogram as one plue (less than 5 mm), two plus(5~10 mm), and three plus(more than 10 mm). Twenty one cases were three plus group and were treated operatively and remaining had conservative treatment. This injury is more prevalent in male with the peak in male with the peak incidence of 21~30 years old age group. The most common site of injury of medial collateral ligament is the mid-portion of the ligament where cross the joint line by the 42.3% on operated cases. The lateral collateral ligament has no specific location of injury but more even on its whole length of femoral or fibullar attachment and mid-portion of the ligament. Results were evaluated in three groups of excellent, good and poor. Six out of 12 cases of conservative treatment and nine out of 21 cases of operative group were excellent in result without joint instability, pain and muscle weakness on walking and flexion was available more than 120 degress. Four cases of conservative treatment group and ten of operative group were good in result with occasional pain on walking, mild degree of instability and range of joint motion between 100 to 120 degrees. Four cases had poor result with pain on walking, marked joint instability and less than 100 degrees of joint motion. Overall result of more than good were 90.5% in operative group and 83.3% in conservative treatment group.
Clinical Study ; Collateral Ligaments ; Humans ; Incidence ; Joint Instability ; Joints ; Knee Joint ; Knee ; Lateral Ligament, Ankle ; Ligaments ; Male ; Muscle Weakness ; Walking

Calcaneus is very important in weight bearing and maintaining the normal contour of the foot. Many diseases can cause the cyst-like destructive changes of the calcaneus. In most cases, histological confirmation and bacteriological examination are necessary for the final diagnosis. In recent years, four cases of the cyst-like destructive lesions of the calcaneus were treated and had satisfactory results. They were confirmed with biopsy and bacterial culture as followings; acute osteomyelitis, chronic osteomyelitis, tuberculous osteomyelitis and simple bone cyst. Operations on the osteomyelitis were curettage with or without sequestrectomy and the simple bone cyst the curettage and bone graft. After operations, proper antibiotics and plaster immobilization followed routinely.
Anti-Bacterial Agents ; Biopsy ; Bone Cysts ; Calcaneus ; Curettage ; Diagnosis ; Foot ; Immobilization ; Osteomyelitis ; Transplants ; Weight-Bearing

A statistical analysis was made on 59 patients of bone tumors who were treated at medical center from March, 1971 to February, 1978. The results were as follows. 1. Thirty nine cases(66%) were benign and twenty cases (34%) were malignant 2. Osteochondroma was the most common benign bone tumor (38.5%) and followed by simple bone cyst(17.9%), enchondroma(10.3%), osteoid osteoma(10.3%) and giant cell tumor(7.7%). 3. The knee joint area was the most common site of osteochondroma(95%) and its peak incidence was in the second decade. 4. Two of three cases of giant cell tumor were recurred at six months and three years after surgical intervention. 5. 11 cases(55%) out of 20 malignant bone tumor were primary tumors of osteogenic sarcoma(9 cases), Ewing's sarcoma(1 case) and multiple myeloma(1 case). Rest of 9 cases(45%) were metastatic bone tumors. 6. The primary organs of the metastatic bone tumor were kidney(2 cases), thyroid and lung(each 1 case), but the 5 cases were undetectable. The most common site of metastasis were spine and pelvis.
Giant Cell Tumors ; Giant Cells ; Humans ; Incidence ; Knee Joint ; Neoplasm Metastasis ; Osteochondroma ; Pelvis ; Spine ; Statistics as Topic ; Thyroid Gland

No abstract available.
Epidural Abscess*