No abstract available.
Cleft Lip* ; Congenital Abnormalities* ; Skin*

PURPOSE: This study was done to evaluate the relationship of stress, coping skill, suicide risk, and suicidal ideation according to treatment phases in patients hospitalized with schizophrenia. METHODS: Participants, 111 patients hospitalized with schizophrenia, were selected from three psychiatric hospitals in G province. Data were collected from March 5 to April 15, 2016 and analyzed using t-test, χ² test, Fisher's exact test, Pearson correlation coefficient, one-way ANOVA, and Scheffé's test analysis with the SPSS/WIN 18.0 program. RESULTS: Based on NOSIE-30, the treatment phases were divided into Beginning, Intermediate, and Completion stages. Patients in the Intermediate stage showed a higher stress level (F=5.13, p=.007) and active coping skills (F=6.70, p=.002) than patients in other stages. They also showed the highest suicide risk (F=7.42, p=.001), and the patients in the beginning stage had the highest suicidal ideation (F=20.20, p<.001. There were significant relationships between study variables at each stage. CONCLUSION: The findings from this study show differences in levels of stress, coping skill, suicide risk, and suicidal ideation according to treatment phases and indicate the need to develop suitable nursing intervention programs according to patients' treatment phases.
Adaptation, Psychological* ; Hospitals, Psychiatric ; Humans ; Nursing ; Schizophrenia* ; Suicidal Ideation* ; Suicide*

Terbinafine is now widely used for the treatment of dermatophytic infections of the skin and nails. Cutaneous side effects of terbinafine are rare and mild. They includes erythema, pruritus, urticaria, desqumation, and macular exanthem. In addition, fixed drug eruption, erythema multiforme, Stevens-Johnson syndrome, and erythema annulare centrifugum-like psoriatic drug eruption were recently described in the literatures. Herein, we reported a case of acute generalized exanthematous pustulosis induced by terbinafine.
Acute Generalized Exanthematous Pustulosis* ; Drug Eruptions ; Erythema ; Erythema Multiforme ; Exanthema ; Pruritus ; Skin ; Stevens-Johnson Syndrome ; Urticaria

No abstract available.
Animals ; Dogs* ; Facial Bones* ; Periosteum* ; Silicone Elastomers* ; Transplants*

No abstract available.
Larva Migrans* ; Philippines*

Duplications of the stomach account for only 3.8% of gastrointestinal duplication, mainly discovered during first year of life. Etiopathogenesis is unknown. The most widely accepted theory is recannalization with fusion of longitudinal epithelial fold. The most frequent presented symptoms and signs include gastric outlet obstruction with vomiting, and palpable mass in the epigatric area. An upper gatrointestinal series usually reveals evidence of extrinsic mass effect of intramural lesion. An abdominal ultrasonographic finding is cystic mass lesion with double layer. Histologically, the wall of intramural cyst is composed of orderly layers of alimentary mucosa, submucosa, and muscle fibers. Recommended management is complete excision & simple closure of duplication without violation of the gastric lumen. In this case, 3-day old male newborn suffered from symptoms of gastric outlet obstruction, multiple gastric duplication cysts were found in pyloric canal and greater curvature. The cystic wall was composed with typical 3 layers of gastric mucosa, submucosa, and muscle fibers. The cystic wall was composed with typical 3 layers of gastric mucosa, submucosa, and muscle fibers. Surgical excision was successfully done.
Gastric Mucosa ; Gastric Outlet Obstruction ; Humans ; Infant, Newborn* ; Male ; Mucous Membrane ; Stomach ; Vomiting

Linear IgA bullous dermatosis (LABD) is an autoimmune subepidermal blistering disease characterized on direct immunofluorescence of perilesional skin by the linear deposition of IgA at the basement membrane zone. The pathogenesis of LABD is not known, but rar ely some cases of LABD have been reported in association with drug exposure. We report a case of drug-induced LABD showing linear deposits of IgA and IgG at the basement membrane zone on direct immunofluorescence of perilesional skin as well as typical clinical and histologic characteristics, although the causative agent could not be specified.
Basement Membrane ; Blister ; Fluorescent Antibody Technique, Direct ; Immunoglobulin A ; Immunoglobulin G ; Linear IgA Bullous Dermatosis* ; Skin

BACKGROUND: Activated coagulation time (ACT) is commonly used to guide heparin and protamine dosing during cardiovascular surgery. There are many factors that influence the ACT such as time of test, hemodilution, temperature, aprotinin and etc. We considered the other factor that influence the ACT, the route of blood sample. METHODS: This study included 40 patients who were scheduled for cardiac surgery. Whole blood was sampled through arterial and central venous line at 10 minutes after surgical incision and heparin administration. The ACT was measured with Hemochron 801 blood coagulation timer with 12 mg of celite surface activator. RESULTS: At 10 minutes after surgical incision and heparin administration, arterial blood and venous blood ACTs were 127 20, 537 214 seconds and 118 18, 496 145 seconds respectively (p<0.05). CONCLUSIONS: We conclude that the venous blood ACT is more less than arterial blood ACT during cardiovascular surgery.
Aprotinin ; Blood Coagulation ; Diatomaceous Earth ; Heart* ; Hemodilution ; Heparin ; Humans ; Thoracic Surgery*

It is known that CD95 (APO-1/Fas) is expressed on the cell surface, and apoptotic cell death can be induced by the CD95 ligation in the cultured, proliferating human retinal pigment epithelial (RPE) cells. However, little is known about CD95 on the non-proliferating RPE cells. In this study, human RPE cells were cultured up to 4 weeks after they reached the confluence, to simulate the non-proliferating RPE cells in situ. There was no significant difference in CD95 expression on the cell surface between the predominantly proliferating, preconfluent cells and predominantly non-proliferating, postconfluent cells in flow cytometric assays. However, unlike proliferating cells, no cellular death occurred in the predominantly non-proliferating cells after the treatment of agonistic anti-CD95 antibody with cycloheximide, pretreated with interferon-gamma. Our results suggest that the CD95/CD95L system probably plays a physiologic role in vivo to remove the abnormal, proliferating RPE cells, and factors other than the surface expression of CD95 may determine the sensitivity to the CD95 signals.
Antigens, CD95/*pharmacology ; Apoptosis/*physiology ; Cells, Cultured ; Human ; Pigment Epithelium of Eye/cytology/*drug effects/*physiology ; Sensitivity and Specificity

BACKGROUND: The number of coronary artery bypass graft surgery without cardiopulmonary bypass is increasing in Korea. This technique avoids a number of the adverse effects associated with cardiopulmonary bypass. But the cardiac exposure and stabilization during off pump coronary artery bypass graft surgery (OPCAB) are known to cause hemodynamic deterioration and it creates new challenges for the anesthesiologist. This study is designed to assess the hemodynamic changes during OPCAB. METHODS: Eighteen patients undergoing OPCAB were included in this study (male/female = 13/5, age = 63.5+/-5.2). An octopus(R), a local cardiac-wall restraining device was applied for stabilization of target coronary artery. Three different surgical settings of exposure and stabilization were used according to the site of anastomosis: left anterior descending artery (LAD), posterior descending artery (PDA) and circumflex branch of left coronary artery (LCx). Heart rate (HR), mean systemic arterial pressure (MAP), central venous pressure (CVP), pulmonary capillary wedge pressure (PCWP) and cardiac output (CO) were measured. CO was measured with thermodilution technique. Stroke volume index (SVI) and cardiac index (CI) were calculated. On each of the surgical settings, hemodynamic parameters were measured at 5 minutes before exposure of target coronary artery, and 5 minutes after placement of the stabilizer and 5 minutes after the completion of anastomosis. RESULTS: During LAD anastomosis, SVI decreased slightly (7.8%), but MAP and CI remained unchanged. During PDA and LCx anatomosis, MAP decreased moderately (15.7% and 16.1%, respectively) and SVI decreased remarkably (24.9% and 32.9%). Also CI did decrease, but it was less remarkable compared to the decrease in SVI due to the increase of HR. CVP and PCWP increased during PDA and Cx anastomosis. When the heart was released, all of the hemodynamic parameters were restored to baseline values. CONCLUSIONS: Hemodynamic changes during OPCAB were remarkable, especially with PDA and LCx reconstruction. However, these changes were transient and they were well tolerated in most patients.
Arterial Pressure ; Arteries ; Cardiac Output ; Cardiopulmonary Bypass ; Central Venous Pressure ; Coronary Artery Bypass ; Coronary Artery Bypass, Off-Pump* ; Coronary Vessels ; Heart ; Heart Rate ; Hemodynamics* ; Humans ; Korea ; Pulmonary Wedge Pressure ; Stroke Volume ; Thermodilution ; Transplants