Hereditary anhidrotic ectodermal dysplasia is a rare condition characterized by underdeveloped ectodermal structure including the skin, teeth or skin appendages. The patient has characteristic feature of anhidrosis, hypotrichosis and defective dentition. We experienced a case of hereditary anhidrotic ectodermal dysplasia in a l-month-old male infant who had unexplained recurring fever, anhidrosis and characteristic facial feature, so we established the diagnosis with clinical feature and skin biopsy.
Biopsy ; Dentition ; Diagnosis ; Ectoderm ; Ectodermal Dysplasia* ; Fever ; Humans ; Hypohidrosis ; Hypotrichosis ; Infant ; Male ; Skin ; Tooth

BACKGROUND: Ivory colored hypopigmentation has been frequently observed in morphea and lichen sclerosus et atrophicus, and also seen after phenol peels, dermabrasion, cryosurgery and post-laser resurfacing. OBJECTIVE: This study was undertaken to investigate the cause of hypopigmentation following autologous suction blister graft (ASBG) in vitiligo patients. METHODS: The ivory lesion and contralateral normal skin were collected by punch biopsies. And the tissues were stained with hematoxylin-eosin, Fontana-Masson, Masson's trichrome, Verhoeff-van Gieson, and S-100 protein to compare the differences between two specimens. RESULTS: H-E and Masson's Trichrome stains showed that compacted hyalinized sclerotic collagens and collapsed, small sized capillaries in the upper dermis were definite in the hypopigmented lesion, whereas norma1 control sites were unremarkable. Elastic fibers were markedly decreased or fragmented in upper dermis of the hypopigmented lesion. Fontanna-Masson stain identified that the lesional epidermis was more hyperpigmented rather than hypopigmented. S-100 stain showed no differences between hypopigmented and contro1 sites. CONCLUSION: The results suggest that the ivory colored hypopigmentation is not caused by the failure of procedure, but by scar formation due to deep freeze; therefore, this kind of complication may be prevented by carefully performing the cryotherapy.
Biopsy ; Blister* ; Capillaries ; Cicatrix ; Collagen ; Coloring Agents ; Cryosurgery ; Cryotherapy ; Dermabrasion ; Dermis ; Elastic Tissue ; Epidermis ; Humans ; Hyalin ; Hypopigmentation* ; Lichen Sclerosus et Atrophicus ; Phenol ; S100 Proteins ; Scleroderma, Localized ; Skin ; Suction* ; Transplants* ; Vitiligo*

We report the clinical features in one patients with episodic positional vertigo and apogeotropic direction changing horizontal positional nystagmus that does not fatigue, beating to the right with the head turned to the left and beating to the left with the head turned to the right. This syndrome probably represents a horizontal semicircular canal variant of benign positional vertigo. Free-floating debris and Cupula attached debris in one horizontal semicircular canal may explain many of the clinical and oculographic findings.
Fatigue ; Head ; Humans ; Nystagmus, Physiologic ; Semicircular Canals ; Vertigo*

Spinal cord infarction as a complication of spine surgery occurs rarely. Herein, a case of spinal cord infarction, which developed in a 69 year old woman following posterior decompression and internal fixation for a T11 bursting fracture, is descirbed. The anesthetic induction and intraoperative course were uneventful, except at the end of the procedure, where her blood pressure suddenly dropped from 130/90 to 90/60 mmHg. The patient was aggressively treated with a transfusion and vasopressor, the blood pressure then returned to its usual value within 10 minutes. However, during a physical examination in the recovery room, the patient was found to have flaccid lower limbs, with impaired sensory function below the T8 level. Her cord diameter had increased, and a high signal lesion was observed within the thoracic spinal cord, from T9 to T12 level on T2-weighted MR images, which was diagnosing as a spinal cord infarction, was and showed no improvement despite the immediate and aggressive treatment.
Aged ; Blood Pressure ; Decompression ; Female ; Humans ; Infarction* ; Lower Extremity ; Physical Examination ; Recovery Room ; Sensation ; Spinal Cord* ; Spine*

A 37-year-old female was presented with an epidermal cyst on her lower back. Histopathologic examination was consistent with an epidermoid cyst with seborrheic verrucalike cyst wall and acantholytic change was also found in the cyst wall. Human papillomavirus(HPV)-specific DNA sequences in paraffin-embedded tissue section were not detected by polymerase chain reaction using HPV consensus primers.
Acantholysis* ; Adult ; Base Sequence ; Consensus ; Epidermal Cyst* ; Female ; Humans ; Polymerase Chain Reaction

Renal oncocytoma has been recently defined histopathologically but many controversies have arised about its origin and differential diagnosis. Until the present time nearly all renal oncocytoma were considered to be benign nature, but rare cases have been reported to be metastasized. We reported a case of renal oncocytoma and synchronous contralateral renal cell carcinoma treated by radical nephrectomy on one side and enucleation on the other side.
Adenoma, Oxyphilic* ; Carcinoma, Renal Cell* ; Diagnosis, Differential ; Nephrectomy

Renal oncocytoma has been recently defined histopathologically but many controversies have arised about its origin and differential diagnosis. Until the present time nearly all renal oncocytoma were considered to be benign nature, but rare cases have been reported to be metastasized. We reported a case of renal oncocytoma and synchronous contralateral renal cell carcinoma treated by radical nephrectomy on one side and enucleation on the other side.
Adenoma, Oxyphilic* ; Carcinoma, Renal Cell* ; Diagnosis, Differential ; Nephrectomy

Cysts of seminal vesicles are rare condition, according to Sharma (1969) et al only 13 true unilateral cases have been reported up to 1969 and apparently 4 were associated with ipsilateral renal agenesis They may be asymptomatic and discovered by rectal examination or may give symptoms of bladder irritation, perineal or testicular pain, urinary obstruction or ejaculatory disturbances. The diagnosis is mainly, based on vesiculography usually performed by retrograde injection of the vas deferens or eventually by direct puncture of the cyst itself. Out patient complained of urethral bleeding and hematospermia, followed by left epididymitis. Both seminal vesicles and ampullas were visualized by the direct injection of contrast media into cyst, suggesting the involvement of the both ejaculatory duct and lower part of seminal vesicles.
Contrast Media ; Diagnosis ; Ejaculatory Ducts* ; Epididymitis ; Hemorrhage ; Hemospermia ; Humans ; Male ; Punctures ; Seminal Vesicles* ; Urinary Bladder ; Vas Deferens

A 35-year-old housewife was diagnosed with onychomycosis and treated by oral terbinafine, 250mg/day, for 4 months. Clinically all infected nails improved gradually. However, her left great toe-nail was not improved thereafter. At that time the proximal end of the onychomycotic lesion was marked with surgical blade, and terbinafine therapy was continued for four weeks. However, the onychomycotic nail was not improved, and the scratch mark passed by the proximal end of the infected nail. Therefore, we detected the resistance to the therapy and switched the medication to itraconazole 100 mg/day and then another scratch mark was done at the proximal end of the onychomycotic lesion. After another 2 weeks the infected nail went along with the scratch mark distally, and showed clinical improvement. After 8 weeks therapy of itraconazole, she was cured clinically and mycologically. The fungal culture was identified as Aspergillus sydowii.
Adult ; Aspergillus* ; Humans ; Itraconazole ; Onychomycosis*

Discoid lateral meniscus is wider and thicker than normal lateral meniscus. The tear pattern and vulnerability to injury of discoid lateral meniscus may be different from that of normal shaped meniscus. Seven hundred and seventy one meniscal tears which were treated arthroscopically between the period of 1982 and 1995 were reviewed retrospectively. Of those cases, tear of normal shaped lateral menisci occupied 327 knees (42.4 %) and discoid lateral menisci 132 knees (17.1 %) representing the higher incidence of tear in normal shaped lateral meniscus. In normal shaped menisci there were no tear in the age of below 10 and there were 37 knees of teens. In discoid lateral menisci, there were 3 knees (2.3 %) of below 10 and 42 knees of teens (31.8 %) that represent higher incidence of younger age group (P<0.05). Tears without trauma history in 31 knees (9.5 %) of normal shaped lateral meniscus and in 70 knees (53.0 %) of discoid menisci represent vulnerability of the discoid lateral meniscus to tear without injury (P<0.05). Symptomatic menisci without tear were noted only in 16 knees (12.1 %) of the discoid lateral menisci. In normal shaped menisci, longitudinal tear within the substance was most common (119 knees, 36.4 %) whereas peripheral tear was most common (57 knees, 43.2 %) in the discoid lateral meniscus, Concealed horizontal tear (11 knees, 8.3 %) and Wrisberg type discoid lateral menisci (2 knees, 1.5 %) was noted only in the discoid lateral meniscus. In summary, discoid lateral meniscus revealed different tear pattern and vulnerability to injury and different age incidence from that of normal shaped lateral meniscus.
Adolescent ; Humans ; Incidence ; Knee ; Menisci, Tibial* ; Retrospective Studies