1.Multilocular Cystic Renal Cell Carcinoma.
Myoung Jin JU ; Kee Tac JANG ; Je Geun CHI
Korean Journal of Pathology 1997;31(11):1240-1243
Multilocular cystic renal cell carcinoma is a distinct subtype of renal cell carcinoma with its pathological characteristics and good prognosis. Multilocular renal cysts and renal cell carcinoma with cystic change are important differential diagnoses. We report a case of multilocular cystic renal cell carcinoma in a 37-year-old woman who came to the hospital because of the right renal mass. The removed right kidney showed a 6x4 cm well defined cystic mass in the lower pole. On cut section there were multiple cavities in the mass, filled with serosanguineous fluid and focal yellowish solid area. Microscopically, these cysts were lined by a single layer of flat or cuboidal cells consisted of clear cytoplasm with small central nuclei. In some portions of the tumor, the clear neoplastic cells formed sheets within the septa or walls of the cysts.
Adult
;
Carcinoma, Renal Cell*
;
Cytoplasm
;
Diagnosis, Differential
;
Female
;
Humans
;
Kidney
;
Multicystic Dysplastic Kidney
;
Prognosis
2.A case report of adenoid cystic carcinoma on maxillary antrum and infratemporal space.
Do Geun JANG ; Yong Gyoo LEE ; Sa Yub KIM ; Jun Yun KIM ; Jin Soo KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(4):583-588
No abstract available.
Adenoids*
;
Carcinoma, Adenoid Cystic*
;
Maxillary Sinus*
3.Associations between Self-Efficacy, Social Capital and Self-Rated Health Status in Healthy Individuals.
Bo Kyoung KIM ; Jin Hyang LEE ; Jang Rak KIM ; Baek Geun JEONG ; Ki Soo PARK
Korean Journal of Health Promotion 2011;11(3):144-153
BACKGROUND: Discrepancies exist in the existing researches regarding the association between social capital and self-efficacy, and most of these researches have been done in developed countries. The aims of this study were to assess the independent association between individual social capital and self-efficacy and to assess the associations between individual social capital, self-efficacy and self-rated health. METHODS: Data were obtained from the Gyeongnam health survey (6,500 persons) conducted in 2008. A self-administered questionnaire was additionally administered to gather information on demographic variables, health behaviors, chronic diseases, self-efficacy, social capital, and self-rated health status. Total study population was 3,843 as those with chronic diseases were excluded. RESULTS: In males, trust was positively associated with confidence and preference to task difficulty, and participation was negatively associated with confidence and positively associated with regulation and preference to task difficulty. In females, trust was positively associated with confidence and preference to task difficulty and negatively associated with regulation. Participation was positively associated with preference to task difficulty. In males, the odds for self-rated health status was better for persons with confidence (95% confidence interval, CI 1.088-1.705), trust (95% CI 1.172-1.821) and participation (95% CI 1.268-2.117). In females, the odds for self-rated health status was better for those with confidence (95% CI 1.250-1.803), preference of task difficulty (95% CI 1.019-1.683) and participation (95% CI 1.024-1.555). CONCLUSIONS: High social capital measured at an individual level may promote self-efficacy and health status.
Chronic Disease
;
Developed Countries
;
Female
;
Health Behavior
;
Health Surveys
;
Humans
;
Male
;
Self Efficacy
;
Surveys and Questionnaires
4.Blood Lead Level and Intelligence among Children.
Duk Hee LEE ; Yong Hwan LEE ; Jin Ha KIM ; In Geun PARK ; Tae Young HAN ; She Han JANG
Korean Journal of Preventive Medicine 1995;28(2):373-385
The association between blood lead children and Intelligent Quotient(IQ) was investigated in a sample of l00 boys and girls aged 6-8 years from one primary school within an industrial area of Pusan. The trained undergraduates in school of public health administered an I.Q. test one by one. Parents answered a questionnaire on demographic, perinatal and socioeconomic variables. Atomic Absorbtion spectrophotometer was used to determine blood lead levels. The geometric mean of blood lead value was 7.99 microgram/dl. In total children, there was no significant relationship between blood lead level and I.Q. But in the children who were born of gestational age of less than 38 weeks, children with higher levels of blood lead performed more poorly on I.Q. test with correlation coefficient from -0.68 to -0.71. But, the children who were born of gestational age of 38 weeks and more were same as total children. These results suggest that exposure to low levels of lead in the children who were born premature probably may result in impaired intelligent development. But, we think that more profound study should be performed with sufficient numbers of subjects.
Busan
;
Child*
;
Female
;
Gestational Age
;
Humans
;
Intelligence*
;
Parents
;
Public Health
;
Surveys and Questionnaires
5.Case of Secondary Amyloidosis in a Patient with Ankylosing Spondylitis Refractory to TNF-alpha Inhibitors.
Min Jin LEE ; Seung Geun LEE ; Eun Kyoung PARK ; Sun Mi JANG ; Sung Min BAEK ; Geun Am SONG ; Geun Tae KIM
Korean Journal of Medicine 2014;87(4):514-519
Secondary amyloidosis occurs in patients with chronic inflammatory diseases, such as rheumatoid arthritis (RA) and ankylosing spondylitis (AS). The major therapeutic approach to secondary amyloidosis involves controlling the underlying inflammatory disease. Tumor necrosis factor-alpha (TNF-alpha) inhibitors have revolutionized the treatment of rheumatic diseases; in many cases dramatic clinical improvement of secondary amyloidosis due to AS has been observed in response to treatment with these agents. However, the development of secondary amyloidosis associated with AS refractory to treatment with TNF-alpha inhibitors has been infrequently reported. Here, we described a case of a 37-year-old male patient with longstanding AS who was diagnosed with secondary amyloidosis due to high disease activity despite treatment with etanercept, adalimumab and infliximab.
Adult
;
Amyloidosis*
;
Arthritis, Rheumatoid
;
Humans
;
Male
;
Rheumatic Diseases
;
Spondylitis, Ankylosing*
;
Tumor Necrosis Factor-alpha*
;
Adalimumab
;
Infliximab
;
Etanercept
6.Does Albumin Infusion Enhance the Diuretic Action of Furosemide in NePhrotic Syndrome?.
Doe Hyeong KIM ; Jae Ho EARM ; Jin Suk HAN ; Hye Young KIM ; Tae Geun OH ; Wooseong HUH ; Jung Sang LEE ; In Jin JANG ; Sang Gu SHIN
Korean Journal of Nephrology 1998;17(4):567-573
There have been controversies on the effect of albumin in treating edema in nephrotic syndrome patients. We evaluated the additive diuretic effect of coadministration of furosernide with albumin in the six patients with nephrotic syndrome. We administered 160mg of furosemide intravenously for 1 hour with 100rnl of 20% albumin or 5% dextrose by random cross-over design. The urine and plasma furosemide concentrations were measured by HPLC. After the administration of furosemide alone, urine volume, urinary excretions of sodium and chloride were increased significantly compared to those of basal state (P<0.05). But, coadministration of furose-mide with albumin did not increase significantly the urine voume (2285+/-445ml vs. 3023+/-715ml), urinary excretions of sodium (194+/-58rnmol/day vs. 282+/-85 mmol/day) and chloride (213+/- 54mmoVday vs. 286+/- 74mmoVday) comparing to those of furosemide only cases. Addition of albumin to furosemide did not significantly changed pharmacokinetic parameters such as AUC (28.3+/-5.5ug/ml hr vs 36.0+/-6.7ug/ml hr), total plasma clearance (115+/-30mVmin vs 108+/-41ml/min), volume of distribution (0.13+/-0.02L/kg vs 0.10+/- 0.01L/kg), elirnination half life (1.4+/-0.3hr vs 1.5+/-0.3hr), and urine furosemide excretion (44+/-8% vs 43+ 10%). We concluded that albumin infusion did not enhance the diuretic action of furosemide pharmacodynamically and pharmacokinetically in patients with nephrotic syndrome.
Area Under Curve
;
Chromatography, High Pressure Liquid
;
Cross-Over Studies
;
Diuretics
;
Edema
;
Furosemide*
;
Glucose
;
Half-Life
;
Humans
;
Nephrotic Syndrome*
;
Pharmacokinetics
;
Plasma
;
Sodium
7.Development of Laryngeal Stroboscopic Effect With Continuous Light Source
Geun-Hyo KIM ; Soo-Geun WANG ; Jeon Yeob JANG ; Yeon-Woo LEE ; Jin-Choon LEE ; Wonjae CHA
Journal of the Korean Society of Laryngology Phoniatrics and Logopedics 2024;35(1):10-14
Background and Objectives:
Most laryngeal imaging modalities used continuous light source. However, videostroboscopy adopted the unique stroboscopic flashing light triggered externally and is consistent with fundamental voice frequencies. If laryngeal stroboscopic effect could be obtained in the field of continuous illumination, it woud be more compatible with conventional video. In this study, we established the mathematical algorithm for stroboscopic effect with continuous light and tried to determine the feasibility of laryngeal stroboscopic effect with conventional laryngoscopy using continuous light in the mechanical model.Materials and Method The mechanical model of fan motor system was used to validate to the present study. Rotational images of the fan motor were captured using conventional laryngoscope with continuous light source.
Results:
On the basis of the mathematical model, the optimal ranges of the frequency for stroboscopic effect were expected as (multiples of sampling rate [S])±(S/5). In the fan motor model, the stroboscopic effects could be confirmed on the basis of the mathematical model using conventional videolaryngoscopy with continuous light source.
Conclusion
Laryngeal stroboscopic effect with continuous light source might be feasible. The stroboscopic effect with continuous light would be expected to provide greater compatibility to integrate with the other imaging modalities for the vocal folds.
8.Intractable Ventricular Arrhythmia Induced by Aconite and its Successful Treatment with Extracorporeal Membrane Oxygenation Support.
Yang Jin KIM ; Ok Geun KIM ; Ji Geon JANG ; Il RHEE ; Woo Youn KIM
Journal of the Korean Society of Emergency Medicine 2014;25(4):471-475
Aconite, derived from the roots of certain aconitum species (Racunculaceae), is widely distributed in Korea. Aconitine, an extremely toxic substance present in aconite, has pharmacological effects, including anti-inflammatory, analgesic, and positive inotropic actions. Due to its relatively low safe dose, we sometimes encounter cases of serious aconite intoxication. The toxic compound mainly affects the CNS, heart, and muscle tissues, resulting primarily in cardiovascular complications. Aconite poisoning presents with a combination of neurological, cardiovascular, and gastrointestinal features. The main cause of death is severe cardiotoxicity causing refractory ventricular tachyarrhythmias and asystole. As there is no specific antidote, management of aconite poisoning is supportive. All patients require close monitoring of blood pressure and cardiac rhythm since ventricular arrhythmias may occur during the first 24 hours of poisoning, resulting in sudden deterioration in the patient's clinical condition. Extracorporeal membrane oxygenation (ECMO) has traditionally been utilized for perioperative cardiac failure and cardiomyopathies. More recently, the indications for ECMO have expanded to patients with acute cardiovascular decompression including intractable arrhythmias. We report on a patient who developed life threatening ventricular tachyarrhythmia after ingestion of herbal tablets containing aconite alkaloids. Our patient was resuscitated with intravenous infusion of amiodarone, repeated cardioversion/defibrillation, and mechanical circulatory support with ECMO.
Aconitine
;
Aconitum*
;
Alkaloids
;
Amiodarone
;
Arrhythmias, Cardiac*
;
Blood Pressure
;
Cardiomyopathies
;
Cause of Death
;
Decompression
;
Eating
;
Extracorporeal Membrane Oxygenation*
;
Heart
;
Heart Arrest
;
Heart Failure
;
Humans
;
Infusions, Intravenous
;
Korea
;
Poisoning
;
Tablets
;
Tachycardia
;
Tachycardia, Ventricular
9.Increasing Prevalence of Vancomycin-Resistant Enterococcus faecium, Expanded-Spectrum Cephalosporin-Resistant Klebsiella pneumoniae, and Imipenem-Resistant Pseudomonas aeruginosa in Korea: KONSAR Study in 2001.
Kyungwon LEE ; Sook Jin JANG ; Hee Joo LEE ; Namhee RYOO ; Myungshin KIM ; Seong Geun HONG ; Yunsop CHONG
Journal of Korean Medical Science 2004;19(1):8-14
The 5th year KONSAR surveillance in 2001 was based on routine test data at 30 participating hospitals. It was of particular interest to find a trend in the resistances of enterococci to vancomycin, of Enterobacteriaceae to the 3rd generation cephalosporin and fluoroquinolone, and of Pseudomonas aeruginosa and acinetobacters to carbapenem. Resistance rates of Gram-positive cocci were: 70% of Staphylococcus aureus to oxacillin; 88% and 16% of Enterococcus faecium to ampicillin and vancomycin, respectively. Seventy-two percent of pneumococci were nonsusceptible to penicillin. The resistance rates of Enterobacteriaceae were: Escherichia coli, 28% to fluoroquinolone; Klebsiella pneumoniae, 27% to ceftazidime, and 20% to cefoxitin; and Enterobacter cloacae, > or =40% to cefotaxime and ceftazidime. The resistance rates of P. aeruginosa were 21% to ceftazidime, 17% to imipenem, and those of the acinetobacters were > or =61% to ceftazidime, aminoglycosides, fluoroquinolone and cotrimoxazole. Thirty-five percent of non-typhoidal salmonellae were ampicillin resistant, and 66% of Haemophilus influenzae were -lactamase producers. Notable changes over the 1997-2001 period were: increases in vancomycin-resistant E. faecium, and amikacin- and fluoroquinolone-resistant acinetobacters. With the increasing prevalence of resistant bacteria, nationwide surveillance has become more important for optimal patient management, for the control of nosocomial infection, and for the conservation of the newer antimicrobial agents.
Anti-Bacterial Agents/*pharmacology
;
Cephalosporins/pharmacology
;
*Drug Resistance, Microbial
;
Enterococcus faecium/metabolism
;
Human
;
Imipenem/pharmacology
;
Klebsiella pneumoniae/metabolism
;
Korea
;
Pseudomonas aeruginosa/metabolism
;
Time Factors
;
Vancomycin/*pharmacology
10.The effect of mouthrinse products containing deep sea water.
Seonah KIM ; Hae Jin JANG ; Yung Geun YOO ; Yong Shik CHU ; Yang Ho PARK ; Jun Woo PARK
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2007;33(6):601-608
The aim of this study was to evaluate the effect of mouthrinse products containing deep sea water. We used original deep sea water (DSW) and processed deep sea water desalinated by reverse osmosis at one time (DDW-1), by reverse osmosis at two times (DDW-2) and concentrated by reverse osmosis (CDW). We made 2 kinds of mouthrinse products containing CDW and other agents for smell and taste and one product without deep sea water. The negative control was distilled water. In vivo study, the dental plaque index scores and the gingival index scores were reduced after 4 weeks mouthrinsing three times daily with 4 kinds of deep sea water and 3 kinds of mouthrinse products(p<0.05). The pH of dental plaque in 1 minute after mouthrinsing was not higher than 5.5 in all solutions, but the pH in 20 minutes after mouthrinsing was higher than 5.7 in DSW, CDW and 3 kinds of products which had higher mineral contents. In vitro study, the mouthrinse solutions containing the higher mineral contents were also the more effective in reduction of methyl mercaptan which is one of the causes of halitosis. The 2 kinds of products containing deep sea water killed Streptococcus mutans (ATCC 25175) in culture plates in one minute. These results indicate the usability of deep sea water in mouthrinses for oral hygiene management.
Dental Plaque
;
Dental Plaque Index
;
Halitosis
;
Hydrogen-Ion Concentration
;
Oral Hygiene
;
Osmosis
;
Periodontal Index
;
Seawater*
;
Smell
;
Streptococcus mutans
;
Water