PURPOSE: We describe clinical assessment of visual internal urethrotomy (VIU) as primary treatment modality in 69 men who presented with complete or partial obstructed urethral stricture. MATERIALS AND METHODS: The 63 patients with partial obstructed urethral stricture were treated by typical VIU. The 6 men with complete obstructed urethral stricture were treated by VIU using sound passed through previously placed suprapubic tract as guide. RESULTS: The procedure was completed successfully in 57 of the 63 men with partial obstructed (90.5%) and 3 of 6 patients with complete obstructed urethral stricture (50%). CONCLUSIONS: VIU is a safe and effective as primary treatment plan when urethral stricture is partial obstructed and the impassable urethral segment is shorter than 1.0cm.
Humans ; Male ; Urethral Stricture*

BACKGROUND: Androgenetic alopecia (AGA) is the most common type of hair loss and is believed to be influenced by family history and genetic factors. However, the exact mode of inheritance has not been well characterized. Although there are some reports on the AGA prevalence in the male family members of paternal side, those of maternal side are rare. OBJECTIVE: The purpose of this study was to elucidate the familial influences in AGA. METHODS: We investigated the AGA prevalence in paternal and maternal male family members (grandfathers and uncles) of 421 Korean male adults with AGA (patients group) and 412 without AGA (control group). Hair loss and family history were assessed by an independent investigator according to Hamilton's classification. RESULTS: The AGA prevalence in male family members of the patients group (30.3%) was higher than those of control groups (8.5%) (p<0.05), and AGA prevalence of paternal side was higher than those of maternal side. However, no difference was found between paternal and maternal AGA prevalence, analysed according to the age of onset and severity of AGA. CONCLUSION: These results suggest that the AGA expression is influenced by familial AGA prevalence and, particularly, paternal AGA prevalence has more effect on AGA expression than maternal AGA prevalence.
Adult ; Age of Onset ; Alopecia* ; Classification ; Hair ; Humans ; Male* ; Prevalence* ; Research Personnel ; Wills

A 59-year old man presented with a 0.5 x 0.3 cm-sized area of, pink-colored, dome-shaped papules on the paranasal area. There was no previous history of trauma to the area. Histopathologic diagnosis was consistent with eccrine poroma. We reported a case of eccrine poroma arising on the paranasal area, an unusual location for this condition.
Diagnosis ; Humans ; Middle Aged ; Poroma*

A 35-year-old woman with advanced lung cancer, treated with intravenous docetaxel and paclitaxel, developed subungual abscesses and secondary onycholysis involving all the finger nails. Bacterial culture demonstrated the growth of Pseudomonas aeruginosa. We report a case of onycholysis and subungual abscesses in a patient treated with docetaxel and paclitaxel.
Abscess* ; Adult ; Female ; Fingers ; Humans ; Lung Neoplasms ; Onycholysis* ; Paclitaxel ; Pseudomonas aeruginosa

We report a case of a 44 year-old man with porokeratosis of Mibelli, who presented with a 10 year history of a 1 cm diameter, well-circumscribed, erythematous, scaly patch with an elevated border on his glans penis. Histologic examination revealed a typical cornoid lamella and absence of an underlying granular layer. The localized type of porokeratosis of Mibelli is most commonly found on the limbs: however, the face, lips, mucosal surfaces, or genital area may instead be involved. We report a case of porokeratosis of Mibelli confined to the glans penis, a very rare site.
Adult ; Extremities ; Humans ; Lip ; Male ; Penis* ; Porokeratosis*

Transepidermal elimination is a spontaneously-developed phenomenon in certain skin disorders, in which altered connective tissue or foreign material is expelled via the epidermis to the exterior. We report a case of a 60-year-old man with a 1x1 cm sized, black-colored nodule, showing transepidermal elimination, on the right shin. Histological examination revealed a pigmented, epidermal cyst, containing deposition of pigment in its wall and cavity. To the best of our knowledge, no pigmented epidermal cysts have been reported in korea to date.
Connective Tissue ; Epidermal Cyst* ; Epidermis ; Humans ; Korea ; Middle Aged ; Skin

No abstract available.
Female ; Humans ; Infertility* ; Pregnancy*

No abstract available.
Animals ; Cricetinae* ; Humans* ; Oocytes*

BACKGROUND: The androgen receptor (AR) is a conserved member of the nuclear receptor superfamily. Differences in the AR gene sequence are characterized mostly by a highly polymorphic trinucleotide repeat (CAG) encoding a polyglutamine stretch in the N-terminal domain. The transactivational activity of the AR might be inversely associated with the numbers of this CAG repeat chain, and the smaller numbers of CAG repeats are believed to be associated with androgenetic alopecia? (AGA). OBJECTIVE: The purpose of this study was to investigate a possible etiologic association between Korean AGA and CAG repeat numbers in the AR gene. METHODS: We compared CAG repeat numbers within the AR gene of 64 male Korean AGA patients with those of 40 normal male controls. RESULTS: There was no significant difference in the number of CAG repeats between the Korean AGA patients and controls. There were no robust or significant correlations between (i) CAG repeat numbers and (ii) age of onset or severity of AGA in Korean AGA patients. CONCLUSION: This study suggests that AR receptor CAG polymorphisms in the Korean male population might not have a major role in susceptibility to AGA expression.
Age of Onset ; Alopecia ; Humans ; Male ; Peptides ; Receptors, Androgen ; Trinucleotide Repeats

BACKGROUND: The androgen receptor (AR) is a conserved member of the nuclear receptor superfamily. Differences in the AR gene sequence are characterized mostly by a highly polymorphic trinucleotide repeat (CAG) encoding a polyglutamine stretch in the N-terminal domain. The transactivational activity of the AR might be inversely associated with the numbers of this CAG repeat chain, and the smaller numbers of CAG repeats are believed to be associated with androgenetic alopecia? (AGA). OBJECTIVE: The purpose of this study was to investigate a possible etiologic association between Korean AGA and CAG repeat numbers in the AR gene. METHODS: We compared CAG repeat numbers within the AR gene of 64 male Korean AGA patients with those of 40 normal male controls. RESULTS: There was no significant difference in the number of CAG repeats between the Korean AGA patients and controls. There were no robust or significant correlations between (i) CAG repeat numbers and (ii) age of onset or severity of AGA in Korean AGA patients. CONCLUSION: This study suggests that AR receptor CAG polymorphisms in the Korean male population might not have a major role in susceptibility to AGA expression.
Age of Onset ; Alopecia ; Humans ; Male ; Peptides ; Receptors, Androgen ; Trinucleotide Repeats