2.Changing Role of Nuclear Medicine for the Evaluation of Focal Hepatic Tumors: From Lesion Detection to Tissue Characterization.
Korean Journal of Nuclear Medicine 1998;32(3):211-224
The role of scintigraphic imaging has moved from the detection of lesions to the tissue-specific characterization of lesions over the past 2 decades. Major advances in nuclear medicine imaging include: 1) positron imaging, 2) improved instrumentation, such as the use of multidetector (dual or triple head) gamma cameras for single photon emission computed tomography, and 3) development of numerous new radiopharmaceuticals for positron or single photon imaging ( labeled glucose analogue, amino acids, fatty acids, hormones, drugs, receptor ligands, monoclonal antibodies, etc). These advanced have resulted in a significantly improved efficacy of radionuclide techniques for the evaluation of various of focal gepatic tumors is reviewed in this article with an emphasis on the clinical applications of various tracer studies and imaging findings.
Amino Acids
;
Antibodies, Monoclonal
;
Carcinoma, Hepatocellular
;
Electrons
;
Fatty Acids
;
Gamma Cameras
;
Glucose
;
Hemangioma
;
Ligands
;
Nuclear Medicine*
;
Radionuclide Imaging
;
Radiopharmaceuticals
;
Tomography, Emission-Computed, Single-Photon
3.Pleomorphic Xanthoastrocytoma: A Case Report.
Soo Chun KIM ; Jong Deok KIM ; Hak Jin KIM
Journal of the Korean Radiological Society 1994;30(4):647-650
PURPOSE: To draw attention to the radiological findings of a benign variant of cerebral astrocytoma in a young patient. MATERIALS AND METHODS: A 24-year-old man with generalized tonic-clonic seizure of 7 years' duration and normal neurological examination was examined with plain skull series, brain CT and MRI, and cerebral angiography. MR imaging was performed with a 0.5 Tesla Toshiba MRT-50A scanner (TIWI, PDWI, T2WI, 0.1 mmol/kg of Gd- DTPA, SE). RESULTS: 1 ) Plain skull series: A radiolucent lesion with a partial radiopaque rim of about 2.5 x 3 cm size in the right anterior parietal bone.2) B rain CT scan: A cystic mass in the right frontoparietal cortex of midconvexity with pressure erosion on the adjacent skull and partial enhancement at outer and anterior portion.3) Brain MRI:A hypointense mass containing a small, intensely enhancing isointensity anterolaterally on Tl-weighted images, which was hyperintense with better delineation of bulging cortical-based appearance on T2-weithted images. No peritumoral edema.4) Cerebral anglography: An avascular mass. CONCLUSION: The diagnosis of pleomorphic xanthoastrocytoma(PXA) should be entertained in patients in whom a superticially placed enhancing intracerebral tumor containing cystic portion that seems to be in contact with the meninges develops during juvenile years.
Astrocytoma
;
Brain
;
Cerebral Angiography
;
Diagnosis
;
Humans
;
Magnetic Resonance Imaging
;
Meninges
;
Neurologic Examination
;
Pentetic Acid
;
Rabeprazole
;
Rain
;
Seizures
;
Skull
;
Tomography, X-Ray Computed
;
Young Adult
4.Accuracy of diagnoses from magnetic resonance imaging of the knee.
Jin Hwan AHN ; Jin Won KIM ; Chun Woo LEE
Journal of the Korean Knee Society 1993;5(1):98-107
No abstract available.
Diagnosis*
;
Knee*
;
Magnetic Resonance Imaging*
5.A clinical & statistical analysis of the facial bone fractures.
Jin Dong KIM ; Tae Yeon KIM ; Chun Eun CHUNG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(1):38-47
No abstract available.
Facial Bones*
6.Amniotic fluid alpha-fetoprotein levels during midtrimester pregnancy (I).
Taek Hoon KIM ; Jong In KIM ; Hyo Jin CHUN
Korean Journal of Perinatology 1993;4(4):498-503
No abstract available.
alpha-Fetoproteins*
;
Amniotic Fluid*
;
Female
;
Humans
;
Pregnancy
;
Pregnancy Trimester, Second*
;
Pregnancy*
7.Behect's Syndrome: Report of Two Cases of Behcet's Sundrome and Review of Literatures.
Young Pio KIM ; Inn Ki CHUN ; Jin Young SHIN
Korean Journal of Dermatology 1974;12(3):133-142
Xeroderma pigmentosum is a hereditary disorder characterized by the ear1y development of pigmentary changes, atrophy, keratoses, and carcinoma, predorninantly light exposed area skin. Two cases of xeroderma pigmentosum complicated. by basal cell Ca. were presented. The one was 15 years old male who had been suffered frorn pea to walnut sized multiple tumors and ulcers on the face with scattered brownish macuIes on the sun exposed area since about 9 years old of his age. The other was 22 years old maIe who had been suffered from the same skin lesions as the former on the face, neck and dorsum of hands. In both cases skin lesions aggravated during each summer seasons and there were on history of convulsions and other neurological symptoms Histopathological findings of tumors on both cases revealed typical findings of basal cell Ca.
Adolescent
;
Atrophy
;
Child
;
Hand
;
Humans
;
Juglans
;
Keratosis
;
Male
;
Neck
;
Peas
;
Seasons
;
Seizures
;
Skin
;
Solar System
;
Ulcer
;
Xeroderma Pigmentosum
;
Young Adult
8.The Evaluation of Self - concept Scale in Cryotherapy of Patient with Warts.
Sang Won KIM ; Hyuk Jin KWEON ; Hyun Chun JO
Korean Journal of Dermatology 1994;32(3):376-382
BACKGROUND: Although warts are known to be caused by viruses, one of their peculiarities is that they may be treated by suggestion therspy or hypnosis. This suggests that psychologic or emotional factors influence the hosts response to the virus lesions. OBJECTIVE: The purpose of the study was to analyze the role of psychologic factors in the therapeutic response of warts. METHODS: The self-concept scale test(Korean Testing Center) was done in all 61 patients with common wsrts before the cryot.herapy from September 1991 to June 1993. Clinical follow-up data were obtained on 50 patients after 2 months, and then were evaluated usir g the self-eoncept scale in treated vs untreated group. RESULTS: 1. The overall cure rate was 56.0%, being higher in females and patients with high education, 1-3 in number of lesions and no previous treatment history as well as in those with less than 1 year of duration. 2. In the comparison of self-concept scale between treated(n=18) and untreated(n=22) groups, the treated group had remarksble results in moral ethical self, personal self and family self scores (p<0.05). Only 14 items were significantly different between two groups(p<0.05 by Wilcoxon rank sum test). 3. Patients of 20 years or more showed a high cure rate(67.79%, p<0.05 by t-test) and demonstrated significance in total positive self score and its self identity, and satisfaction, self behavior, physical self, moral ethical self and family self scores(p<0.05, by t-test). CONCLUSION: The self-cancept significantly related to the positive aersonality, harmonious family, stable self-esteem and high normal ethics, may influence at least the therapy to the warts in the treated patients in contradistintion to the untreated ones.
Cryotherapy*
;
Education
;
Ethics
;
Female
;
Follow-Up Studies
;
Humans
;
Hypnosis
;
Warts*
9.The Studies of the Pathogenicity of Demodex Folliculorum and the Treatment of Demodididosis.
Young Pio KIM ; Inn Ki CHUN ; Jin Young SHIN
Korean Journal of Dermatology 1976;14(1):5-16
The pathogenicity of Demodex folliculorum (DF) is not well established, becausc this cutaneous parasite can be found very often not only from acneic skin lesions but also on healthy human skin, surface, particularly on sebaceous gland-rich and functionaIly active areas of the skin, i.e. on face, and therefore, the mite has been generally considered as normal inhabitant of human skin. However, as is the case with candidiasis, the parasite could also be pathogenic in the state of disturbed host-para-site relationship. To find out the pathogenicity of the mite, the authors studied the incidence of finding DF from different sites of face in several groups of 60 acneic patients (various types of acne vulgaris and rosacea) and 30 normal subjects as control. And the results obtained were as follows: the mite was found in 33 cases out of the acnei patients (55%), in male patients 67% (12 out of l8) were positive and in fernales 50% (21 out of 42). In the control group of 3O (15 each sex), 17 cases (9 males and 8 females) had thc mite, the incidence rate being 57%, The incidence rate of DF in various types of acneic skin lesions were: 85% in rosacea. 80% in pustular acne 71% in cvstic acne and 32% in papular acne. The distribution of the mite in various sites of the face differed markedly in the acneic and normal groups. In the control group 17 (57 %) were positive on nose, 3 (10%) on cheek, 2 (7%) on chin, and none on the forehead. Among 60 acneic patients, however, 18 (30%) were positive on cheek, 17 (28%) on nose, 15 (25%) on chin 12 (20 %) on forehead. In addition, the acuthors observed two cases of demodicidosis in the dogs. These two dogs were siblings and lived together with other dogs of the same lineage, but the other dogs were not affected. In spite of vigorous treatment with 15 % benzyl benzoate aqueous emulsion and 10 % crotamiton ointment applied topically for two to three weeks, the dogs died within one to two months. Slight improvement only was noted in the first week of the treatment, but the dogs were gradually emaciated, leading to death. At the onset of the disease, both dogs were two to three months old. Histopathological studies of the affected skin revealed dense patchy lymphocytic infiltration predominantly in perifollicular area, follicular keratotic plugging and egg-like materials in the Iumen of hair follicle. Histopathology of the affected canine skin appeared similar to that of human demodicidosis except that the mitelike material was observed lodged in the lumen of hair follicle. The morphology of demodex folliculorum canis seemed slightly different from that of the human strain (DF hominis). It is generally smaller in size and has narrower and shorter stunted abdomen than human strain, otherwise it is almost alike. The human demo3icrdosis can be effectively treated with 15% benzyl benzoate aqueous emulsion, 1% gamma benzene hexachlrode cream and 10 % crotamiton ointment, and it seems to be most effective agent being crotamiton ointment among them. It is suggested that demodex folliculorum, which has been hitherto thought to be harmless, can be pathogenic in certain individuals and that some immunologic factors might be implicated in the process of the demodicidosis.
Abdomen
;
Acne Vulgaris
;
Animals
;
Benzene
;
Benzoates
;
Candidiasis
;
Cheek
;
Chin
;
Dogs
;
Dronabinol
;
Forehead
;
Hair Follicle
;
Humans
;
Immunologic Factors
;
Incidence
;
Male
;
Mites
;
Nose
;
Parasites
;
Rosacea
;
Siblings
;
Skin
;
Virulence*
10.Clinical effect of topical ketoconazole in seborrheic dermatitis of scalp.
Seong Jin KIM ; Young Ho WON ; Inn Ki CHUN
Korean Journal of Dermatology 1992;30(5):625-632
An etiologic agent in seborrheic dermatitis is now considered to be due to Pityrosporum ovale. The connection between the yeast and the disease has been clearly dernonstrated in a number of patients treatd with antifungal agents. However, the fact, that Pityrosporum ovale (Pityrosporum orbiculare) belongs to the normal human cutaneou. flora makes it difficult, to explain the role of the organism in seborrheic dermatitis. In this clinical study, twenty eight subjects were divided into two group by treatment regimen of topical 2% ketoconazole shampoo(TKS)and 0.3% prednisolone valerate solution (PVS). Before and during the four weeks treatment periods, the number of Pityrosporum ovale on the scalp were evaluated by scrub Giemsa staining method, which estimat,ed by score scale, under direct. microscopic examination. Also clinical symptoms including erythema, scales and itching were recorded by scores every week and compared between two treatment group. Topical application of 2% ketoconazole shampoo(TKS) is a very effective treatment regimen to reduce the yeasr cell score(from 5.8+1.3 to 1.8+1.4) than PVS(from 6.4+1.3 to 3.5+1.5), significantly(p<0.05). So the results of this study acconsistent with the view that density of Pityrosgourum ovale plays a role in the cause and course of seborcheic derrnatitis on the scalp. And antifungal agent(TKS) shows favorable effects ori tnis disease clinically and mycologically.
Antifungal Agents
;
Azure Stains
;
Dermatitis, Seborrheic*
;
Erythema
;
Humans
;
Ketoconazole*
;
Malassezia
;
Prednisolone
;
Pruritus
;
Scalp*
;
Weights and Measures
;
Yeasts