No abstract available.
Barium* ; Enema* ; Intussusception*

Congenital ectodermal dysplasia are a group of familial disorders that affect tissues and organs of ectodermal origin to varying degrees. It devided hidrotic type and anhidrotic type by geneologic origin and distinct clinical manifestationa. The hidrotic type usually trait by autosomal dominant gene and manifested dystrofic nails, defect of hair and eyebrow and palmoplantar hyperkeratosis. This patient is 16 year oId male. He had been dystrophic nails, alopecia since at birth, thereafter palmoplantar hyperkeratosis, clubbing fingers noted. C.R.C. Urinalysis, stool examination, chest x-ray were within normal limit. Biopsy specimen from palm revealed hyperkeratosis, hypergranulosis, acanthosis and, mild inflamrnatory cell infiltrate on upper dermis. Biopsy speeimen from the scalp revealed norrriaI findings except slight hypoplasia of ebaceaus gland.
Alopecia ; Biopsy ; Dermis ; Ectoderm ; Ectodermal Dysplasia* ; Eyebrows ; Fingers ; Genes, Dominant ; Hair ; Humans ; Male ; Parturition ; Scalp ; Thorax ; Urinalysis

No abstract available.
Gonadotropin-Releasing Hormone*

This study was done on 171 volunteers in order to investigate the present status of cutaneous normal flora of Candida species and the distribution of Candida species on the normal human skin in dermatologic clinic of Korea University Hospital from January, ]984 to December, 1984. Among the 171 volunteers, 115 strains of Candida species were identified by culture on the Sabouraud's dextrose agar media, germ tube test, sugar assimilation test, sugar fermentaion test and culture on corn meal with Tween 80 media, The results were summarized as follows: 1. The incidence of cutaneous normal flora of Candida species was 13, 5,5 (115 species among 855 sites) 2. Candida species were distributed in oral cavity(45 species), 4th interdigital toe web(39 species), groin(12 species), axilla(11 species) and 4th interdigital finger web(8 species) in order of frequency. 3, Of ll5 species, 45 species were cultured in summer, 27 species in autumn, 18 species in winter and 14 species in spring. 4 Of 115 Candida species, C. albicans(88 species), C. parapsilosis(12 species), C, tropicalis(8 species), C. guilliermondii(3 species) and C. stellatoidea(2 species) were identified. Two species could not be identified.
Agar ; Candida* ; Fingers ; Glucose ; Humans* ; Incidence ; Korea ; Meals ; Polysorbates ; Skin* ; Toes ; Volunteers ; Zea mays

No abstract available.
Animals ; Phenol* ; Rats*

No abstract available.
Cerebral Palsy*

A study of concentration smear, culture for AFB and sensitivity test for antituberculous drugs was carried out in 810 patients who had been admitted in SNUH in the period of 12 months from January 1976 to December 1976. Acid-fast bacilli was confirmed in 110 cases (13.6%) by concentrated direct smear and in 88 cases(10.9%) by culture, and concomitantly sensitivity test was performed in 26 isolated cases. Streptomycin, INH, PAS, Kanamycin and Ethionamide were rather less sensitive to the strains of Mycobacterium tuberculosis, but all strains obtained during the period of this study were highly sensitive to Rifampicin.
Ethionamide ; Humans ; Kanamycin ; Mycobacterium tuberculosis ; Mycobacterium ; Rifampin ; Streptomycin

No abstract available.
Cholelithiasis* ; Korea*

OBJECTIVES: The present study aims to investigate the effects of physical illness on depression in North Korean Defectors. METHODS: One hundred forty-four North Korean Defectors(20 males, 124 females) and 376 South Koreans 133 males, 243 females) in Incheon Metropolitan areas participated the present study. Face-to-face interview was conducted for demographic information including presence of physical illnesses. To investigate depressive symptoms, all participants were required to complete the Center for Epidemiologic Studies-Depression scale (CES-D). RESULTS: After controlling gender, age, marital status, educational year, employment status and physical illness, North Korean Defectors showed higher CES-D score than South Koreans(beta=0.449, p<0.001). Within North Korean Defectors, the presence of physical illnesses independently was related to higher CES-D score(beta=0.243, p<0.001). However, within South Koreans, the presence of physical illnesses did not significantly predict CES-D score. North Korean Defectors with physical illness have higher CES-D score than North Korean Defectors without physical illness(26.8+/-13.8 versus 19.7+/-12.7). However, there was no significant differences of CES-D score between South Koreans with physical illness and South Koreans without physical illness(10.3+/-9.8 versus 9.3+/-8.8). CONCLUSION: Compared to South Koreans, North Korean Defector showed higher depressive symptoms independently from gender, age, education, employment, marriage. In addition, only North Korean Defectors showed the relationship between depression and physical illness. Our study suggests that depression should be assessed when North Korean Defectors have physical illness.
Depression ; Employment ; Humans ; Male ; Marital Status ; Marriage

To search the effective antisense oligonucleotide that inhibit the growth of Herpes simplex virus type 1 (HSV-1), six kinds of phosphorothioate oligodeoxynucleotides (S-ODNs) were synthesized and the antiviral activity was assessed by measuring cytopathic effect in Vero cells infected with HSV-1. Of the three dodecamer S-ODNs, cornplernentary to the translation initiation site of IE2 (AS2) and scrambled S-ODN (AS1) showed more significant antiherpetic activity than AS4 complementary to the IE4. Accordingly, the antiviral effect of dodecamer S-ODN was not specific. In contrast to the no inhibitory effect of sense strand S-ODN of ICP8 (AS6), two S-ODNs complementary to the translation initiation site of ICP8 (AS3) and that of IE1 (AS5) showed potent antiherpetic activity assessed in vitro HSV-1 virus yield assay. Antiherpetic effect of AS3 was decreased in proportion to the addition of AS6. The synthesis of viral protein ICPS and IE1 were inhibited in AS3 and AS5 treated HSV-1 infected Vero cells, respectively. These findings suggest that antiherpetic effect of AS3 is specifically mediated by targeting ICPS. S-ODNs had no effect on Vero cell viability. The data suggest that the 19-mer S-ODNs may be effective in antiviral chemotherapy.
Drug Therapy ; Herpes Simplex* ; Herpesvirus 1, Human ; Oligodeoxyribonucleotides ; Phosphorothioate Oligonucleotides* ; Simplexvirus* ; Vero Cells