Edwards syndrome is first introduced by Edwards and characterized by facial anomalies, multiple cardiovascular, gastrointestinal, urogenital, and skeletal malformations. It results from triplication of part or all of chromosome 18 in some or all of the patient's cells. It has an incidence of 1 in 4,500 live births or less and short life expectancy. Recently we experienced a case of 3-day-old female new born infant with this syndrome. Post mortem examination showed progeric face with prominent occiput, large flabby ears, microphthalmia, and micrognathia, bilateral clenched hands with flexion contraction of middle fingers, and bilateral rockerbottom feet. Internal examination revealed horseshoe kidney, esophageal atresia with tracheoesophageal fistula, two accessory spleens, and multiple cardiac anomalies. A trisomy 18 was confirmed by the cytogenetic study.
Infant ; Male ; Female ; Infant, Newborn ; Humans ; Incidence

A teratoma is a true tumor which is composed of a variety of cell types representative of more than one germ layer. These neoplasms are principally encountered in the ovaries and testes. Rarely teratoma arises in the midline of the body such as anterior mediastinum, retroperitoneum, sacrococcygeal region, intracranial cavity, neck, and abdominal viscera, presumably from primitive sequestrated cell nests during embryogenesis. The teratoma is mostly benign in histology and biology, however, rarely cancer develops in preexisting benign cystic teratoma. The prostatic gland is an unusual site of the teratoma and so we report a case of teratoma which arose in the prostatic gland and underwent malignant change.
Biology ; Embryonic Development ; Female ; Germ Layers ; Mediastinum ; Neck ; Ovary ; Pregnancy ; Prostate ; Sacrococcygeal Region ; Teratoma* ; Testis ; Viscera

An eccrine squamous syringometaplasia (ESS) is defined as a mature squamous metaplasia of the eccrine ducts. The clinical and pathological features of an ESS are presented. Syringometaplasia is a rare lesion, mostly occuring in the extremities, and as far as we know, no report on the ESS has been published in Korean literature. We experienced a case of an ESS occured in a 15 year-old male, who had a tender erythematous plaque in the right knee. The histologic examination revealed some scattered nests of metaplastic squamous epithelium in the deep dermis, associated with acute nonspecific panniculitis. The importance of the ESS is that it histologically simulates the well differentiated squamous cell carcinoma. The histopathologic findings were discussed and a brief review of the literature was made.
Adolescent ; Carcinoma, Squamous Cell ; Dermis ; Epithelium ; Extremities ; Humans ; Knee ; Male ; Metaplasia ; Panniculitis

No abstract available.

A statistical observation was made on 267 in-patients with age distribution and operative procedures in the Department of Urology, National Seoul Hospital, during the period from January 1. 1976 to December 31, 1978.
Age Distribution ; Seoul ; Surgical Procedures, Operative ; Urology*

The retroperitoneal space is that indefinite area in the lumber and iliac region which lies between the peritoneum and the posterior wall of the abdominal cavity. The term retroperitoneal cyst or tumor is usually confined by the pathologist to these arising from the structures situated in the retroperitoneal space. Retroperitoneal cysts are that of non-neoplastic nature and originated from retroperitoneal tumor Because the retroperitoneal space is rather extensive and adjacent organs are easily displaced, many of the cysts grow to a large size before giving any clinical manifestation. Frequently, when the patient is first seen, there is an indefinite abdominal mass the exact nature of which is obscure, and the diagnosis is not made until the time of surgical investigation.
Abdominal Cavity ; Diagnosis ; Humans ; Peritoneum ; Retroperitoneal Space

No abstract available.
Epidemiology*

This study is standard surgical measurement of the size of kidney in normal Korean population that might be basic data of renal size in comparison with radiographic and ultrasonographic measurement for clinical implies. The 235 cases of donors for renal transplantation were measured by the length, width, thickness, weight and the outer diameter of renal vessels as well as identification of branches of renal vein at the time of donor nephrectomy. These data were tested to statistically significant by T- test, ANOVA, Pearson correlation analysis and multivariate analysis. The mean values of renal size were 11.6+/-0.87 (9.2-15.4cm) x 6.1+/-0.81 (4.4-10.0cm) x 4.9+/-0.75(2.2-7.1cm) for male 11.7+/-0.77 (9.8-14.0cm) x 6.2+/-0.85 (4.5-10.0cm) x 5.O+/-0.77 (2.8- 7.1cm) and for female 11.4+/-0.96 (9.2-15.4cm) x 6.0+/-0.75 (4.4-8.2cm) x 4.8+/-0.7 (2.2-7.0cm). The mean value of renal weight were 183.1+/-36.92 (115.0-370.0gm) : for male 188.2+/-40.10 (120.0-370.0gm) and for female 177.6+/-32.41 (115.0-300.0gm). The width, thickness and weight of kidney were larger in male than in female (p<0.05). I found out that the age of donors did not affect the renal length, width, thickness and weight (p>0.05). The renal length, width, and weight increased proportional to the body weight (p<0.05). The renal thickness and weight were different in each range of the body height (P<0.05). The body weight had correlation with renal length (r=0.25), thickness (r=0.32), weight (r=0.36, p<0.001) and width (r=0.16, p<0.05). The body height was correlated well with renal length (r=0.20), thickness (r=0.18) and weight (r=0.25, p<0.05). The body weight was the most reliable factor affecting renal size and weight in multivariate analysis (p<0.05). The mean number of branches of renal vein was 0.36+/-0.63 (0.0-2.0) in right kidney and 3.12+/-0.76 (1.0-6.0) in left one. The mean diameter of the renal artery was 0.61+/-0.132 (0.3-1.0cm) and the mean diameter of the renal vein 1.46+/-0.132 (0.50-2.20cm). The radiographic measurement of renal size was larger than our surgical measurement. The mean renal length and width in radiographic measurement(IVP) were 12.1+/-0.70cm in right kidney, 12.1+/-0.65cm in left one and 6.4+/-0.54cm in right kidney, 6.8+/-0.45cm in left one versus 11.6+/-0.87cm, 11.6+/-0.89cm and 6.1+/-0.81cm, 6.1+/-0.84cm in surgical measurement. Surgical measurements of renal size of donors at the time of renal transplantation were real renal size despite of radiographic and ultrasonographic measurement and provided basic standard data for Korean population that might be utilized in approaching renal disease.
Adult* ; Body Height ; Body Weight ; Female ; Humans ; Kidney ; Kidney Transplantation ; Male ; Multivariate Analysis ; Nephrectomy ; Renal Artery ; Renal Veins ; Tissue Donors

No abstract available.
Radionuclide Imaging*

A clinical observation was made on 150 patients of urolithiasis who admitted to the Department of Urology, National Seoul Hospital during the 5 years period from January, 1976 to December. 1980. The results were as follows; 1. The incidence of the patients with urolithiasis was 29.2% of the in-patients (513 cases) and male to female ratio was 2.75 : 1. 2. The great majority of urinary calculi occurred it patients between the ages of 21 and 40 (64.7%). 3. A seasonal occurrence was highest during summer on 34.0%. 4. The locational distribution of urinary calculi were 59.4% in the ureter, 28.8% in the kidney, 9.3 % in the bladder, and 3.3% in the urethra. 5. The most favored predilection site of ureteral stone was lower third in 57.3% of all cases. 6. The pyuria was showed in 66.7% and microscopic hematuria was revealed in 54.0%. 7. The clinical symptoms of upper urinary tract lithiasis showed flank pain in 82.4%, hematuria in 32.1%. nausea and vomiting in 25.2%, but, in lower urinary tract, frequency was 84.2%. hematuria and painful urination were each 63.2%. 8. The most surgical intervention was ureterolithotomy in 25.3%. 9. The results of chemical analysis of 76 urinary calculi showed the mixed type of calcium phosphate and calcium oxalate in 38.2% (29 cases), calcium phosphate in 18.4% (14 cases), calcium oxalate in 15.8% (12 cases), the mixed type of calcium phosphate and ammonium phosphate in 11.8% (9 cases) and calcium carbonate in 5.3% (1 cases). The major component of urinary calculi was calcium-phosphate oxalate.
Ammonium Compounds ; Calcium ; Calcium Carbonate ; Calcium Oxalate ; Female ; Flank Pain ; Hematuria ; Humans ; Incidence ; Kidney ; Lithiasis ; Male ; Nausea ; Pyuria ; Seasons ; Seoul ; Ureter ; Urethra ; Urinary Bladder ; Urinary Calculi ; Urinary Tract ; Urination ; Urolithiasis* ; Urology ; Vomiting