No abstract available.
Autopsy* ; Diagnostic Errors*

PURPOSE: In Korea, Lung cancer is the Second most common prevailing malignancy among male population next to stomach cancer. Although CT scan and MRI is widely used in the staging of lung cancer, plain chest x-ray still plays an important role in screening and diagnosis. Our intention was to review the confusing radiographic features which result in delayed diagnosis of lung cancer. MATERIALS AND METHODS: Of the 160 patients with lung cancer evaluated by us, 62 patients(39%) with delayed diagnosis had average diagnostic duration of 5.1 months compared with 2.1 months for those without delay. We reviewed the plain chest x-ray findings of those 62 patients. RESULTS: The diagnosis of lung cancer was delayed more than half of the cases under the impression of intrathoracic tuberculosis. Upon reviewing the roentgenologic findings in patients with diagnostic delay, central type appeared as a small hilar or mediastinal mass with or without obstructive pneumonia. Peripheral type appeared as an ill-defined pulmonary nodule, a nodule hidden by overlapping structures, or as a lung cancer associated with pulmonary tuberculosis. Some cases were misinterpreted as extranodal spread of malignancy. CONCLUSION: To solve above mentioned problems, we recommend proper understanding of natural history of lung cancer, incorporation of high kVp technique in chest radiographs, routine acquisition of lateral chest radiograph to increase diagnostic accuracy, and appropriate use of CT scan in cases of difficult diagnosis.
Delayed Diagnosis* ; Diagnosis ; Humans ; Intention ; Korea ; Lung Neoplasms* ; Lung* ; Magnetic Resonance Imaging ; Male ; Mass Screening ; Natural History ; Pneumonia ; Radiography, Thoracic ; Stomach Neoplasms ; Thorax ; Tomography, X-Ray Computed ; Tuberculosis ; Tuberculosis, Pulmonary

Bronchogenic cyst is relatively uncommon disease in clinical practice, 15 cases of bronchogenic cyst wereobtained and X-ray findings were analized retrospectively. The results are as follows: 1. 5 patients were symptomfree (30%) and common symptoms and signs were hemoptysis, dyspnea, chest pain in order of frequency. 2. 9 patientswere female and 6 patients were male. The most common age group was 21 years old to 30 years old(40%) and the nexcomon age group was 31 years old to 40 years old (20%) 3. 9 cases of intrapulmonary bronchogenic cyst and 6 casesof mediastinal bronchogenic cyst were obtained. 4. The average size of bronchogenic cyst was about 8x7x6cm. 5. Thecommon location of intrapulmonary bronchogenic cyst was lower lobe (56%) and common x-ray findings was thin walledcyst with air fluid level(78%). 6. Bronchography was performed in 3 cases of intrapulmonary bronchogenic cyst andonly one case demonstrated comunication with bronchus. 7. All 6 cases of mediastinal bronchogenic cyst showed wellmarginated soft tissue mass density. 3 cases were performed CT scanning and average precontrast Hounsfield numberwas 51 unit. No case showed contrast enhancement.
Bronchi ; Bronchogenic Cyst ; Bronchography ; Chest Pain ; Dyspnea ; Female ; Hemoptysis ; Humans ; Male ; Retrospective Studies ; Tomography, X-Ray Computed

We report a case of colonic type-papillary adenocarcinoma of appendiceal origin in a 73-year-old male patient. The patient presented with right lower quadrant mass and was operated for a preoperative diagnosis of inflammatory small bowel mass. The mid one-third of the appendix showed a 3.5x3.3 cm sized, broad-based, intraluminal papillary mass. Microscopically, it was a well differentiated papillary adenocarcinoma and revealed a strong immunoreactivity to carcinoembryonic antigen. Tumor desmoplasia and acute inflammatory change were prominent.
Male ; Humans ; Adenocarcinoma

No abstract available.
Animals ; Blood Platelets* ; Butylated Hydroxytoluene* ; Rats* ; Streptococcus* ; Thrombin*

DNA methylation is one of many epigenetic mechanisms that regulate gene expression in the human body. From the view of epigenetics, there are two phases of development, one for germ cell development and another for embryo development. This review will discuss the basic mechanism of methylation, its role in gene expression, and the role of methylation in embryonic reprogramming. Methylation of genes is very critical to embryo development and should be explored further in order to increase our understanding of development.
DNA ; DNA Methylation ; Embryonic Development ; Epigenomics ; Female ; Gene Expression ; Germ Cells ; Human Body ; Methylation ; Pregnancy

The purpose of this study was to compare the corrosion characteristics between implant fixture and two types of abutment screw; gold screw, titanium screw. The anodic polarization behavior, the galvanic corrosion behavior, and the crevice corrosion behavior of prepared samples were investigated using potentiostat and scanning electron microscope. The results were as follows : 1. Anodic polarization behavior of samples: The primary passivation potential of implant fixture was -420mV, implant abutment was -560mV, titanium screw was -370mV and gold screw was -230mV. All samples were shown to have a high corrosion potential and good formation of passive film. The critical passive current density of gold screw was higher than of other samples and the sample of gold screw showed a unstable passive film formation at passive region. 2. Galvanic corrosion behavior of samples: Contact current density between implant fixture and titanium screw showed 8.023x 10-5C/cm2. Contact current density between implant fixture and gold screw showed 5.142x 10-5C/cm2. 3. Crevice corrosion behavior of samples : The crevice corrosion resistance of sample using titanium screw was higher than that of sample using gold screw, and a severe corrosion morphologies were observed at the fixture-screw interface by the scanning electron microscope.
Corrosion* ; Titanium

Chest CT scans of 70 patents with malignant lymphoma were reviewed to evaluate the thoacic manifestation of malignant lymphoma. Sixteen patients had Hodgkin's disease and 54 patients had non-Hodgkin's lymphoma. The thoracic involvement of malignant lymphoma was observed i 47 patients (67.1%) and 11 of these patients had Hodgkin's disease, and 36 had non-Hodgkin's lympoma. The most common finding was mediastinal lymphadenopathy and the most frequently involved sites were anterior mediastinal and paratracheal lymph nodes. Pulmonary parenchymal involvement was seen in 11 patients (15.7%), and CT scan showed thickening of bronchovascular bundle, parenchymal consolidation and nodules. Pleural effusion was seen in 18 patients (25.7%), however, without any evidence of parietal pleural thickening in all cases. Involvement of chest wall and breast was seen in two patient(2.9%). The data obtained through the current study showed no differences from those of previous reports, except the fact that there was no CT evidence of pleural thickening in patients who had pleural effusion.
Breast ; Hodgkin Disease ; Humans ; Lymph Nodes ; Lymphatic Diseases ; Lymphoma* ; Lymphoma, Non-Hodgkin ; Pleural Effusion ; Rabeprazole ; Thoracic Wall ; Tomography, X-Ray Computed

No abstract available.
Adult* ; Humans ; Mycoplasma* ; Pneumonia, Mycoplasma*

No abstract available.
Carcinoma, Bronchogenic*