Objective To find a grading method for assisting in evaluating hypoxia degree of patients with pulmonary heart disease non-invasively. Methods To design a quantitative method to score degree of hypoxia of 67 patients with pulmonary heart disease by using acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ) as a frame and to make comparative analysis between the grading result and artery blood gas to find the correlation. Results There was a negative correlation between evaluation mark and pH、PaO2、SaO2 and a positive correlation between the evaluation mark and PaCO2, according to statistics. Conclusions Although the grading table of hypoxia evaluation can not substitute blood gas analysis, acting as a non-invasive method to assist in evaluating the hypoxia degree of patients with pulmonary heart disease, it can not only relieve patients' repeated punctuation pain, but also achieve the goal of estimating hypoxia.Consequently the non-invasive method to evaluate hypoxia is of clinical value.

Adolescent ; Child ; Child, Preschool ; Electroencephalography ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Status Epilepticus ; diagnosis ; drug therapy ; etiology

The paper described such functional modules as user login,prescription management,prescription review management,statistics of prescription review results,log management,user management and background data maintenance,as required in the circular Management Regulations on Hospital Prescription Review(Trial).Discussions in the paper focused on the structuring methods and design highlights of the prescription review system,which aim at improving the efficiency and accuracy of prescription review,and its networking with HIs and information sharing.

BACKGROUND: The tissue-engineered scaffold, as a substitute of autogenous bone graft, plays an important role in bone repair. In the meanwhile, three-dimensional (3D) printing technology has obtained more attention because of its accurate adjustment.OBJECTIVE: To review the in vitro or in vivo studies on the 3D-printed scaffolds applied in bone repair, thus providing basis for clinical research.METHODS: The first author searched the PubMed database using the English keywords of tissue engineering, bone,three-dimensional printing, scaffold for pertinent articles addressing 3D-printed tissue-engineered scaffolds.RESULTS AND CONCLUSION: There are plenty of studies on 3D-printed tissue-engineered scaffolds, and recent research focuses on the material selection and surface modification. The appropriate porosity is vital, and with the development of manufacturing technology, each property of the scaffold is improved, and composite materials prevail gradually. All above improvements enhance the mechanical property and promote cell adhesion and proliferation.Furthermore, the surface modification promotes the implant-bone interaction. In vivo and in vitro research both indicate that composite materials with the surface coating of bone induction can improve the scaffold performance and osteogenesis.

Up to present,the research of the early-warning system for the risk of the medical quality has been carried out both at home and abroad.The majority of these researches aimed at providing theoretical guidance for the scientific decision-making of local health departments.In order to construct quality of medical care evaluation indicators system.On the bases of intelligence research,drawing on a series of internationally recognized quality of medical care evaluation system.The majority of these researches aimed at providing theoretical guidance for the scientific decision-making of local health departments.However,the hospital-related research is very limited.Therefore,hospitals were selected as objects in this study.33 experts from 6 three"A" hospitals were selected.And by using a series of internationally recognized quality health care system as a source of reference and focusing on process control and standardizing of management,the early-warning system for the risk of the medical quality has been constructed based on the combination of theory and practice.At the same time,Delphi method was used to verify the results repeatedly to form a set of early-warning system for the risk of the medical quality which is objective,scientific and approved by experts.

As an important inflammatory cytokine, tumor necrosis factor-α (TNT-α) plays an important role in the process of cerebral ischemia-reperfusion. The discussion of the dynamic changes, the mechanism of neurotoxicity and antagonizing the therapeutic effect of TNF-α in the process of cerebral ischemia-reperfusion injury will provide theoretical basis for the treatment of cerebrovascular diseases.

Protons and heavy ion radiation therapy have proven highly effective against a wide range of cancers and in recent decades there have been rapid advances.Due to the physical characteristics of the Bragg-peak and superior biological properties,proton and heavy ion radiation is able to focus its energy on the tumor while minimizing exposure to surrounding normal tissues and organs,which is expected help enhance the tumor dose and reduce normal tissue damage.In recent years,many studies have explored the efficacy and safety of proton and heavy ion radiotherapy on various malignancies,such as head and neck cancer,lung cancer,esophageal cancer,and liver cancer.The results of these studies enable a better understanding of the characteristics and advantages of proton and heavy ion therapy.

OBJECTIVE:To determine the content of 5 kinds of heavy metal elements in Astragalus membranaceus from Longxi of Gansu province,i.e. Pb,Cd,Cu,As,Hg. METHODS:Wet digestion pretreatment was carried out for samples and atomic absorption spectrometry (AAS) was used for the determination of heavy metal elements. RESULTS:The contents of 5 kinds of heavy metal elements in A. membranaceus from Longxi of Gansu Province were lower than the limit. CONCLUSION:AAS method can accurately determine the content of heavy metal elements in A. membranaceus.

Objective To analyze the effect of Kangfuxin Liquidon on gingiva groove liquid interleukin 1β(IL-1β), prostaglandin E2 (PGE2), soluble adhesion molecule-1 (sICAM)in fixed orthodontic patients with gingivitis. Methods 96 cases of patients with fixed orthodontic gingivitis consult the draw method were divided into control group and experimental group, 48 cases in each group. The control group were treatedby gums clean, experimental group based on the control group were treattedby Kangfuxin Liquidon. The IL-1β, PGE2, sICAM-1 levels, periodontal status, the grade of swelling and pain, the clinical curative effect were compared between two groups. Results After treatment, the IL-1β, PGE2, sICAM levels of experimental group were lower than the control group (10.54±1.41) ng/L vs.(11.85±1.71)ng/L, (284.62±35.21) ng/L vs.(314.65±39.48)ng/L, (150.49±18.11) μg/L vs.(162.83±20.26) μg/L,the differences were statistically significant (P<0.05).The periodontal status, swelling and pain grading ofexperimental group were better than control group (P<0.05). Theeffective rate of experimental group was higher than the control group (95.83%vs.79.17%) (P<0.05). Conclusion Kangfuxin Liquidon can reduce fixed orthodontic patients with gingivitis gingiva groove IL-1β, PGE2, sICAM-1 levels, improve the periodontal status, relieve swelling and pain, improve the clinical curative effect.

An animal model of hemorrhagic shock is widely applied .It is an important platform to clarify the pathogenic mechanism, develop hemostasis materials , test first aid equipments and filter resuscitation medications .This paper summa-rizes the commonly used animal models of hemorrhagic shock at home and abroad , focusing on animal selection , model cre-ation, influencing factors , and fields of application in order to provide useful reference for model selection and application by medical practitioners and researchers .