1.Clinical Study and Therapeutic Experience in Tinea Versicolor ( 3 ).
Korean Journal of Dermatology 1995;33(2):280-286
BACKGROUND: Tinea versicolor may be treated by topical oroal antifungal drugs. OBJECTIVE: Ihe objertive of this study was to evaluate the their, peutic effect and safety of oral itraconazole(100-200mg/day), cloconazole cream, 20% sodium chiosulfate solution, sulconazole cream and 2% ketoconazole shampoo in Tinea versicolor. METHODS: Forty patients with Tinea versicolor were studys clinically and treated in five groups, with oral itraconazxale(100-200mg/day), cloconazole crean 20% sodium thiosulfate solution, sulconazole cream and 2% ketoconazole shampoo, from JuIIy 1991 to June, 1994. The writers also compared the results with the writers previous similar studies in 1986, 1990. RESULTS: The average age was 29.9 years, the oldest patient were 52 year-old and the youngest patient was a 14 year-old. The ratio of male to female a 1.2: 1. The distributions of lesions was most common in the axilla(26.9%), and the other sitsuere the anterior chest(19.2%), the back(17.3%), the neck(15.4%), the upper extremites(9.6%) the abdomen(7.7%) and the lower extremites(3.9%), in order. The incidence of hyperpigrietted lesions was 76.8% and of hypopigmented lesions was 23.2%. The average duration of treatment until cure was 3.00+0.55 weeks in the oral itraconaxile treated group, 3.31+1.18 weeks in the cloconazole cream group, 3. 25+1.03 weeks in the 20%, sodium thiosulfate solution group 3.45+0.52 weeks in the sulconazole cream group and 3.40+0.33 weeks in the 2% ketoconazole shapen group. Mere were no statistically significant differences of therapeutic efficacy in each the five groups(p>0.05). Compared with the study in 1990, the average age was higher from 5.7 to 29.9 years, and the male to female ratio was slightly less, showing a relative increase in male incidence. But, there was no statistical difference in therapeutic efficacy(p>0.05). CONCLUSION: This study was shown that the above five theraieric regimens can be used safely and simply, according to patients preferences.
Adolescent
;
Female
;
Humans
;
Incidence
;
Ketoconazole
;
Male
;
Middle Aged
;
Sodium
;
Tinea Versicolor*
;
Tinea*
2.A Study of Fluorescence Pattern of Immune Deposits in Bullous Pemphigoid and Epidermolysis Bullosa Acquisita.
Korean Journal of Dermatology 1994;32(4):626-630
Backgraund : Most of the inflammatory bullous lesions in bullous pamphigoid(BP) and epidermolysis bullosa acquisite(EBA) demonstrate similar clinical and histological features. However, the specificities of the autoantibodiea reactive to the dermo-epidermal junction antigeins are different. In these two bullouk dermat loses, there are no remarkable differences in symptomaiology, there are no unique predilection sites for the lesions and they do not usually leave scars after nvolution. Considering these similarities, dermatologists could encounter some clinical confuiion in maling a provisional diagnosis. OBJECTIVE: Authors examined three patients of BP with classic inflammatory bullous eruptions and threa patients of EBA with inflammatory bullous lesions to see if here were any differences in the morphology of the immuno-fluorescence(IF) pattern. METHODS: For direct IF of vertical or semi-vertical sections, perilasional skin was obtained in each patient for indirect IF of horizontal or semi-horizonta1 sections, Ig(bound substrates were prepared from all these autoantibody-positive individuals. All specimens veri; observed at 200/400-magnification fields through an ordinary fluorescence microscopy. RESULTS: Patterns of fluorescence observed by direct IF were characterized as thin-linear in BP and thick/coarse-linear in EBA along the basement membrane zone. On the horizontal section preparations in indirect IF, the patterns of fluorescence were clean-linear in E3P hnd more fluffy-linear in EBA at the dermoepidermal junction, These patterns could be recognized aim/larly in the fields of both 200 and 400-magnification, however each minor differences were not easy to distinguish each other. CONCLUSION: The above findings of subtle differences in the pattern of IF may provide some suggestions to the examiners for the need of differential diagnosis in theae riseases.
Basement Membrane
;
Blister
;
Cicatrix
;
Diagnosis
;
Diagnosis, Differential
;
Epidermolysis Bullosa Acquisita*
;
Epidermolysis Bullosa*
;
Fluorescence*
;
Humans
;
Male
;
Microscopy, Fluorescence
;
Pemphigoid, Bullous*
;
Skin
3.A Study of Fluorescence Pattern of Immune Deposits in Bullous Pemphigoid and Epidermolysis Bullosa Acquisita.
Korean Journal of Dermatology 1994;32(4):626-630
Backgraund : Most of the inflammatory bullous lesions in bullous pamphigoid(BP) and epidermolysis bullosa acquisite(EBA) demonstrate similar clinical and histological features. However, the specificities of the autoantibodiea reactive to the dermo-epidermal junction antigeins are different. In these two bullouk dermat loses, there are no remarkable differences in symptomaiology, there are no unique predilection sites for the lesions and they do not usually leave scars after nvolution. Considering these similarities, dermatologists could encounter some clinical confuiion in maling a provisional diagnosis. OBJECTIVE: Authors examined three patients of BP with classic inflammatory bullous eruptions and threa patients of EBA with inflammatory bullous lesions to see if here were any differences in the morphology of the immuno-fluorescence(IF) pattern. METHODS: For direct IF of vertical or semi-vertical sections, perilasional skin was obtained in each patient for indirect IF of horizontal or semi-horizonta1 sections, Ig(bound substrates were prepared from all these autoantibody-positive individuals. All specimens veri; observed at 200/400-magnification fields through an ordinary fluorescence microscopy. RESULTS: Patterns of fluorescence observed by direct IF were characterized as thin-linear in BP and thick/coarse-linear in EBA along the basement membrane zone. On the horizontal section preparations in indirect IF, the patterns of fluorescence were clean-linear in E3P hnd more fluffy-linear in EBA at the dermoepidermal junction, These patterns could be recognized aim/larly in the fields of both 200 and 400-magnification, however each minor differences were not easy to distinguish each other. CONCLUSION: The above findings of subtle differences in the pattern of IF may provide some suggestions to the examiners for the need of differential diagnosis in theae riseases.
Basement Membrane
;
Blister
;
Cicatrix
;
Diagnosis
;
Diagnosis, Differential
;
Epidermolysis Bullosa Acquisita*
;
Epidermolysis Bullosa*
;
Fluorescence*
;
Humans
;
Male
;
Microscopy, Fluorescence
;
Pemphigoid, Bullous*
;
Skin
4.Flowcytometric analysis of postoperative immunosuppression.
Journal of the Korean Cancer Association 1993;25(6):966-974
No abstract available.
Immunosuppression*
5.Two Cases of Extramammary Paget' s Disease Showing a Good Response to Radiotherapy.
Jin Bok KIM ; Young Suck RO ; Young Tae KIM
Korean Journal of Dermatology 1995;33(6):1172-1178
We report the clinical evolution of two elderly male patients with extramammary Paget's disease who were treated with radiotherapy. Both cases primarily involved the scrotum and penile root, and were not associated with any underlying or visceral malignancy. The total doses administered were 6000 cGy and 3000 cGy, respectively. A good clinical response was achieved in both cases. No major side effects were observed. The patients are being followed for any signs of recurrence and have been completely asymptomatic to date
Aged
;
Humans
;
Male
;
Paget Disease, Extramammary
;
Radiotherapy*
;
Recurrence
;
Scrotum
6.Fibroepithelial Polyp of Vagina with Atypical Stromal Cells: A case report.
Mi Ok PARK ; Yong Jin KIM ; Jae Bok PARK
Korean Journal of Pathology 1998;32(8):619-921
A case of fibroepithelial polyp with stromal atypia in a 25-year-old female is described. The tumor arose from the vaginal wall and measured 3.5 cm in maximal diameter. It was composed of hypercellular connective tissue stroma and focal myxoid area containing numerous atypical mono- and multinucleated stromal cells. These cells may mislead to make a diagnosis of sarcoma, particulary of botryoid rhabdomyosarcoma.
Adult
;
Connective Tissue
;
Diagnosis
;
Female
;
Humans
;
Polyps*
;
Rhabdomyosarcoma
;
Sarcoma
;
Stromal Cells*
;
Vagina*
7.A clinical study of fistula-in-ano.
Sun Bok WEE ; Jin Young KIM ; Jong Ha SON
Journal of the Korean Surgical Society 1991;41(4):503-509
No abstract available.
8.Quality of life after total gastrectomy in the gastric cancer patients.
Jin Bok KIM ; Kyung Suk SEO ; Ma Hae CHO
Journal of the Korean Cancer Association 1993;25(2):159-165
No abstract available.
Gastrectomy*
;
Humans
;
Quality of Life*
;
Stomach Neoplasms*
9.A Case of Bilateral Persistent Hyperplastic Primary Vitreous.
Jin Kuk KIM ; Jong Bok LEE ; Hong BoK KIM
Journal of the Korean Ophthalmological Society 1989;30(2):311-314
Persistent hyperplastic primary vitreous(PHPV) is a congnital abnormality of the embryonic intraocular vasculature, resulting from the failure of regression of the primary vitreous in a full-term infant. PHPV is usually unilateral and characterized by leukocoria, elongated ciliary process, microphthalmia, cataract, rubeosis iridis, shallow anterior chamber, and secondary glaucoma. PHPV finally develops into retinal detachment, intractable glaucoma, and pthisis bulbi. Surgical treatment, involving lensectomy and vitrectomy, is not successful and poor visual result is obtained due to retinal abnormalities. A one-month-old girl was found to have persistent hyperplastic primary vitreous in both eyes, and she expired of unknown etiology at home 2 months after diagnosls.
Anterior Chamber
;
Cataract
;
Female
;
Glaucoma
;
Humans
;
Infant
;
Microphthalmos
;
Persistent Hyperplastic Primary Vitreous*
;
Retinal Detachment
;
Retinaldehyde
;
Vitrectomy
10.Prognostic significance of epidermal growth factor receptor expression in human gastric carcinoma.
Woo Ho KIM ; Sang Yong SONG ; Ki Young CHOI ; Yong Il KIM ; Jin Bok KIM
Journal of the Korean Cancer Association 1993;25(1):78-84
No abstract available.
Epidermal Growth Factor*
;
Humans*
;
Receptor, Epidermal Growth Factor*