Objective:To observe the effect of magnesium sulfate combined with nifedipine on preeclampsia blood pressure and pregnancy outcomes. Methods:The data of 62 patients with preeclampsia were retrospectively studied. According to the treatment reg-imen, the patients were divided into the control group (30 cases) with magnesium sulfate treatment and the observation group (32 ca-ses) with magnesium sulfate combined with nifedipine treatment. The blood pressure before and after the treatment, as well as the clin-ical efficacy, pregnancy complications and pregnancy outcomes in the two groups were compared. Results:After the treatment, systolic and diastolic blood pressure of the patients in the two groups were significantly lowered when compared with those before the treatment (P<0. 05), and the decrease in the observation group was more significant than that in the control group (P<0. 05). The total effec-tive rate of the observation group was 96. 88%, which was significantly higher than that of the control group (73. 33%, P<0. 05). The incidence of uterine inertia, postpartum hemorrhage, fetal distress and placental abruption in the observation group was significant-ly lower than that in the control group (P<0. 05), and the rate of cesarean section and neonatal asphyxia in the observation group was also significantly lower than that in the control group(P<0. 05). Conclusion:Magnesium sulfate combined with nifedipine in the treat-ment of preeclampsia shows notable antihypertensive effect, which can reduce the incidence of pregnancy complications and adverse pregnancy outcomes. Therefore, the combination exhibits better efficacy than magnesium sulfate alone.

Endoscopy ; Humans ; Nasal Septum

Objective To evaluate the impact of warmed and humidified CO2 on the gynecological laparoscopic operation. Methods We searched keywords related to gynecological laparoscopic and CO2 pneumoperitoneum temperature and humidity on Pubmed and Wanfang database, then analyze the postoperative pain, analgesic consumption, core temperature, operation time, length of hospital stay. Results 17 publications included into the meta analysis after screening. Compared with the standard laparoscopy, warmed and humidified CO2 can reduce postoperative pain and prevent intraoperative hypothermia. No significant difference in postoperative analgesic consumption, postoperative core temperature, duration of recovery and hospital stay, endoscope lens fog and operation time. Conclusions Only few beneficial effects on postoperative pain and core temperature have been identified in this meta-analysis, though more studies are probably needed to study the real impact of warmed and humidified CO2 for laparoscopic procedures.

Objective With the sole object of glycyrrhizic acid products,the methods were investigated for Glycyrrhiza uralensis genomic DNA transformation into Hansenula anomala by nitrogen and argon ion implantation.Methods The genomic DNA from G.uralensis was randomly transferred into H.anomala by nitrogen and argon ion bombardment.The recombined yeasts were cultured by the slant and liquid cultivation,in which the contents of glycyrrhizic acid and glycyrrhetic acid were determined by acetic anhydried-H2SO4 qualitative test and RP-HPLC determination.Results Five recombined yeast strains that produced glycyrrhizic acid and glycyrrhetic acid were obtained.After cultured in liquid medium for 96 h,the highest content of glycyrrhizic acid in the cultivation liquid was 114.49 mg/L and that of 18?-glycyrrhetic acid and 18?-glycyrrhetic acid were respectively 0.56 and 0.81 mg/L by RP-HPLC.A kind of unknown red component was found in the cultivation liquid of one recombined strain by TLC.Conclusion The recombined yeast strains of producing glycyrrhizic acid could be obtained G.uralensis genomic DNA transformation into yeast mediated by the ion implantation.

The performance evaluation of science and technology management personnels could stimulate their enthusiasm and advance the development of science.In this article,a 3-dimensional model was set up based on the evaluating criteria,the evaluating objects & the familiarity between the appraiser and the objects,which was simplified from several complicated factors necessary in the process of evaluation.Compared with the traditional methods,this 3D model sheds more light on choosing the critical factors,which helps improve the accuracy and rationality of scientific evaluation.

Objective: To observe the expression of CD36 in peripheral monocytes in patients with Type 2 diabetes, and to study the influence of rosiglitazone on CD36 expression and the related the mechanism. Methods: The expression of CD36 in the peripheral monocytes of patients with Type 2 diabetes was measured by flow cytometry before and after rosiglitazone treatment; the correlation between monocytes CD36 expression and metabolic index was analyzed. Results: Flow cytometry showed that the mean fluorescence intensity (MFI) of monocyte CD36 in Type 2 diabetes was significantly higher than that in the healthy controls(745.9±281.3 vs 406.3±80.2, P<0.01). CD36 MFI in patients with Type 2 diabetes atherosclerosis was significantly higher than that in patients with Type 2 diabetes non-atherosclerosis (878.2 ± 296.1 vs 584.2 ± 148.3, P<0.01). Besides, we also found that CD36 expression, fasting blood glucose(FBG), post-prandial blood glucose(PBG), hemoglobin A1c(HbA1c), FIN, PIN, and HOMA-IR were all significantly decreased after rosiglitazone intervention compared with those before rosiglitazone intervetion and placebo group(P<0.05 or P<0.01). There was a positive correlation between monocyte CD36 expression with FBG(r=0.55, P<0.05), HbA1c(r=0.62, P<0.01), and HOMA-IR(r=0.64, P<0.01); but the expression was not correlated with PBG, FIN, or PIN. Conclusion: The increased expression of CD36 in monocytes of patients with Type 2 diabetes may be one of the mechanisms for accelerated atherosclerosis in diabetic patients. Rosiglitazone can decrease CD36 expression in monocytes through effectively controlling the blood glucose and decreasing insulin resistance.

Adult ; Biopsy ; methods ; Bronchoscopy ; Humans ; Lung ; pathology ; Male ; Middle Aged ; Pneumoconiosis ; diagnosis ; pathology

According to the property of military health service positioning , armed forces all over the world invariably put military health service into combat team ranks .They want to strengthen the ties between the health system and the military system by adjusting the health command and management system in order to meet the needs of multi -level and multi-directional wartime support in the future .This paper summarizes the development of foreign ( the US.Germany and Russian Federation) and our military health command and management system , and make a detailed comparison .It may be a practical and valuable research for the current military health reform .

Rectal cancer is a common malignancy in the alimentary tract with an increasing incidence, the current treatments of which include surgery, radiotherapy, chemotherapy, and integrated comprehensive options. Sexual dysfunction, especially erectile dysfunction (ED), is one of the commonest complications in men after rectal cancer treatment and is generally attributed to the damage to the pelvic autonomic nerves. However, recent studies show that ED after rectal cancer treatment is a complex pathophysiological process associated with neurogenic, vasculogenic, and psychological factors. This article reviews the pathogeneses of ED after rectal cancer treatment in order to provide some theoretical evidence for its prevention and treatment.
Erectile Dysfunction ; etiology ; Humans ; Male ; Postoperative Complications ; etiology ; Rectal Neoplasms ; surgery