No abstract available.
Probiotics

Fear-related behaviors are rigidly controlled by the medial prefrontal cortex (mPFC). The mPFC is activated by the prosocial hormone oxytocin, which plays an important role in social buffering. We used a slice patch current-clamp recording in single- and pair-exposed rats who were subjected to electric shocks, to determine the cellular mechanism of the action of oxytocin in the mPFC under social buffering conditions. Pair-exposed rats showed a significant reduction in both freezing and passive avoidance behaviors compared to single-exposed rats. It was observed that input resistance in pyramidal neurons decreased in both single- and pair-exposed rats than naïve rats, but input resistance in interneurons increased in pair-exposed rats than single-exposed rats. We found that the number of action potential (AP) spikes in the mPFC pyramidal neurons decreased significantly in pair-exposed rats than in single-exposed rats. The pyramidal neurons in the mPFC were similarly regulated by oxytocin in singleand pair-exposed rats, while the number of AP spikes in interneurons by oxytocin decreased in single-exposed rats, but there was no significant change in pair-exposed rats. Therefore, our findings reveal that a decrease in mPFC pyramidal neuronal activity in pair-exposed rats through social interaction induces a reduction in fear-related behavior via obstruction of fear-memory formation; however, no such reduction was observed in single-exposed rats. Moreover, we suggest that the oxytocin-mediated decrease in neuronal activity in the mPFC could facilitate social buffering.

PURPOSE: This study was done to identify the effects and relationships of humor, job satisfaction, job stress and intent to turnover for nurses and suggest a theoretical structural path diagram among the variables. METHODS: Data were collected at 6 hospitals located in Seoul, and Gyeonggi Province, from June to September, 2010. Participants were 275 nurses. Data were analyzed using Amos 19.0 for Structural Equation Modeling. RESULTS: Humor had significant effects on job satisfaction (beta=.15, t=2.29, p=.022) and indirect effects on the intent to turnover in this model (chi2=44.18, df=23, RMSEA=0.05, TLI=0.97). But humor did not affect job stress unlike results of previous studies (t=-.02, p=.771). CONCLUSION: Humor may not affect job stress under the very stressful conditions of the health care environment. The model showed the effect of humor contributed to increases in job satisfaction but did not decrease job stress. Higher levels of job satisfaction could decrease the intent to turnover. Consequently, humor would be helpful in increasing job satisfaction to diminish nurse turnover. Further studies are suggested to investigate causal relationships among humor, burnout, and other emotional and organizational variables.
Delivery of Health Care ; Intention ; Job Satisfaction

PURPOSE: This study attempted to examine the influence of resilience, life satisfaction, and psychological well-being on attitude to death. METHODS: A predictive correlational design was used. The participants were 184 nursing students from three universities of Korea. They responded to a self-report questionnaire, with items on demographics, resilience, life satisfaction, psychological well-being, and attitude to death. RESULTS: The mean score for attitude to death was 2.77±0.39 (range, 1–4), and a significant difference was observed depending on age, grade, and death-related education. Attitude to death was positively correlated with death-related education, resilience, life satisfaction, and psychological well-being. Results of the hierarchical multiple regression analysis indicated that death-related education and psychological well-being were significant predictors of attitude to death, explaining 26.6% of the latter. The most important factor was psychological well-being. CONCLUSION: Although death-related education and psychological well-being are two of the most influential factors among nursing students, no more than 30.4% of this study’s participants received death-related education. Death-related education is necessary to help nursing students so that they can cope positively with stressful situations by finding positive meaning. It is necessary to develop a systematic curriculum so that these students can establish a positive attitude to death.
Attitude to Death ; Curriculum ; Demography ; Education ; Humans ; Korea ; Nursing ; Personal Satisfaction ; Students, Nursing

PURPOSE: This study attempted to examine nursing students' self-esteem, interpersonal relationships, and self-efficacy, to identify factors affecting empathy. METHODS: A predictive correlational design was used. The participants in this study were nursing students from fours university of Korea. The questionnaires were administered to a convenience sample of 147 nursing students in the Republic of Korea. RESULTS: Mean item scores for self-esteem, interpersonal relationship, self-efficacy, and empathy were 3.83, 3.63, 3.30, and 3.44, respectively (possible range, 1–5). Empathy was correlated with self-esteem, interpersonal relationships, and self-efficacy. The multiple regression analysis revealed that 45.9% of the variance in empathy is attributable to gender, major satisfaction, self-esteem, self-efficacy, and interpersonal relationships. The most important factor interpersonal relationship explained. CONCLUSION: Improving nursing students' major satisfaction, self-esteem, self-efficacy, and interpersonal relationships are strategies that may foster empathy.
Empathy* ; Humans ; Korea ; Nursing* ; Republic of Korea ; Self Efficacy ; Students, Nursing

Purpose: This study aims to identify the knowledge, risk perception, fear, self-efficacy, and preventive behaviors among nursing students, and factors influencing preventive behaviors on COVID-19. Methods: Data was collected from March, 2022 to May, 2022. The participants included 218 nursing students in their 3rd and 4th grade of three universities in two cities. Results: The knowledge of COVID-19 was 13.54 out of 15 points, risk perception was 4.83 out of 8 points, fear was 13.26 out of 35 points, self-efficacy was 19.96 out of 25 points, and preventive behaviors were 7.56 out of 9 points. The explanatory power of self efficacy (β = .21, p = .002), which affects preventive behaviors was 67.0%. Conclusion Based on the results of this study, it is necessary to develop a systematic nursing intervention that improves self-efficacy to improve preventive behaviors against COVID-19 among students. This study’s result can be used in the future to develop appropriate health policies and program to prevent emerging infectious diseases.

PURPOSE: This study attempted to examine the influence of resilience, life satisfaction, and psychological well-being on attitude to death. METHODS: A predictive correlational design was used. The participants were 184 nursing students from three universities of Korea. They responded to a self-report questionnaire, with items on demographics, resilience, life satisfaction, psychological well-being, and attitude to death. RESULTS: The mean score for attitude to death was 2.77±0.39 (range, 1–4), and a significant difference was observed depending on age, grade, and death-related education. Attitude to death was positively correlated with death-related education, resilience, life satisfaction, and psychological well-being. Results of the hierarchical multiple regression analysis indicated that death-related education and psychological well-being were significant predictors of attitude to death, explaining 26.6% of the latter. The most important factor was psychological well-being. CONCLUSION Although death-related education and psychological well-being are two of the most influential factors among nursing students, no more than 30.4% of this study’s participants received death-related education. Death-related education is necessary to help nursing students so that they can cope positively with stressful situations by finding positive meaning. It is necessary to develop a systematic curriculum so that these students can establish a positive attitude to death.

This study was done to investigate the 12 college volleyball player's food behavior, nutrient intakes, and their serum lipid levels during the periods of training and detraining and to provide basic data for an effective progrm for the volleyball players during the period fo detraining after the game season. The results were summarized as follows : The total daily energy intake of the players was 3,363+/-339kcal and3,692+/-499kcal during the periods of the training and detraining, respectively. During the training period, daily intakes of protein, calcium and vitamin A, and B2 were lower than the recommended dietary allowance for the players. During the detraining period, the players' daily intakes of calcium, iron, and vitamin A were even lower. However, the consumption of alcohol was dramatically increased during the period of detraining. The levels of serum triglyceride and very low density lipoprotein were significantly increased during the detraining period. Basal metabolic rates were significantly increased after the training period and diastolic pressure was decreased during the detraining period. In conclusion, out results suggest that the detraining of volleyball players for 10 days after intensive training, negatively affects their food behavior and serum lipid concentrations. Therefore, for the improvement of performance for the next game season, a planned program for the players' detraining period should be developed.
Basal Metabolism ; Blood Pressure ; Calcium ; Energy Intake ; Feeding Behavior ; Food Habits* ; Iron ; Lipoproteins ; Recommended Dietary Allowances ; Seasons ; Triglycerides ; Vitamin A ; Volleyball*

Although several findings of historical writings have been made, the exact role of the thyroid was not known in the ancient times. From the middle of the nineteenth century, the anatomy and the physiological role of the thyroid were gradually elucidated, and diagnostic and therapeutic modalities were developed. It has been 100 years since Theodor Kocher was awarded the Nobel Prize for his work in pathophysiology and surgery of the thyroid. Fifty years have passed since radioactive iodine was first used for the diagnosis and the treatment of hyperthyroidism in Korea. Today, thyroid cancer is one of the most prevalent malignancy in Korean women. However, the detailed history of the thyroid disease has not been introduced in Korea. The aim of this paper is to describe the historical perspectives of the thyroid disease, especially focusing on the development of the treatment. The common thyroid disease ere named after their discoverers, such as Graves and Hashimoto. It is meaningful to understand the historical background of the thyroid gland, because the important concepts in the area of endocrinology such as hormone replacement therapy, feedback mechanisms, and the use of isotopes were first established based on the research of the thyroid.
Female ; History, 19th Century ; History, 20th Century ; Humans ; Thyroid Diseases/*history ; *Thyroid Gland/physiopathology/surgery ; Thyroid Neoplasms/history

Nodular fasciitis is a pseudosarcomatous reactive process composed of fibroblasts and myofibroblasts, and it is most common in the upper extremities. Nodular fasciitis of the external auditory canal is rare. To the best of our knowledge, less than 20 cases have been reported to date. We present a case of nodular fasciitis arising in the cartilaginous part of the external auditory canal. A 19-year-old man complained of an auricular mass with pruritus. Computed tomography showed a 1.7 cm sized soft tissue mass in the right external auditory canal, and total excision was performed. Histologic examination revealed spindle or stellate cells proliferation in a fascicular and storiform pattern. Lymphoid cells and erythrocytes were intermixed with tumor cells. The stroma was myxoid to hyalinized with a few microcysts. The tumor cells were immunoreactive for smooth muscle actin, but not for desmin, caldesmon, CD34, S-100, anaplastic lymphoma kinase, and cytokeratin. The patient has been doing well during the 1 year follow-up period.
Actins ; Calmodulin-Binding Proteins ; Desmin ; Ear ; Ear Canal* ; Erythrocytes ; Fasciitis* ; Fibroblasts ; Follow-Up Studies ; Humans ; Hyalin ; Keratins ; Lymphocytes ; Lymphoma ; Muscle, Smooth ; Myofibroblasts ; Phosphotransferases ; Pruritus ; Upper Extremity ; Young Adult