Purpose: This study conducted a concept analysis of rejection sensitivity using the Walker and Avant method, to clarify its defining attributes, antecedents, and consequences. So, this contributes to a deeper understanding of its role in interpersonal relationships. Methods: Walker and Avant’s framework, this concept analysis included a thorough literature review across multiple disciplines. The literature was extracted from databases such as PubMed, Web of Science, CINAHL, and RISS. Results: Rejection sensitivity is a psychological construct encompassing several attributes, including rejection expectation, perception of rejection, and reaction to perceived rejection. This trait is influenced by various antecedents, including early life experiences, attachment style, and cultural factors. The consequences or events associated with rejection sensitivity span multiple domains and can significantly affect an individual’s life. Conclusion According to interpersonal psychology and attachment theory, problem behavior in adolescents is a state of unsatisfied affection for parents and a response to feelings of unacceptance. Rejection sensitivity is particularly important in the Korean culture because of cultural factors.

Purpose: This study conducted a concept analysis of rejection sensitivity using the Walker and Avant method, to clarify its defining attributes, antecedents, and consequences. So, this contributes to a deeper understanding of its role in interpersonal relationships. Methods: Walker and Avant’s framework, this concept analysis included a thorough literature review across multiple disciplines. The literature was extracted from databases such as PubMed, Web of Science, CINAHL, and RISS. Results: Rejection sensitivity is a psychological construct encompassing several attributes, including rejection expectation, perception of rejection, and reaction to perceived rejection. This trait is influenced by various antecedents, including early life experiences, attachment style, and cultural factors. The consequences or events associated with rejection sensitivity span multiple domains and can significantly affect an individual’s life. Conclusion According to interpersonal psychology and attachment theory, problem behavior in adolescents is a state of unsatisfied affection for parents and a response to feelings of unacceptance. Rejection sensitivity is particularly important in the Korean culture because of cultural factors.

Purpose: This study conducted a concept analysis of rejection sensitivity using the Walker and Avant method, to clarify its defining attributes, antecedents, and consequences. So, this contributes to a deeper understanding of its role in interpersonal relationships. Methods: Walker and Avant’s framework, this concept analysis included a thorough literature review across multiple disciplines. The literature was extracted from databases such as PubMed, Web of Science, CINAHL, and RISS. Results: Rejection sensitivity is a psychological construct encompassing several attributes, including rejection expectation, perception of rejection, and reaction to perceived rejection. This trait is influenced by various antecedents, including early life experiences, attachment style, and cultural factors. The consequences or events associated with rejection sensitivity span multiple domains and can significantly affect an individual’s life. Conclusion According to interpersonal psychology and attachment theory, problem behavior in adolescents is a state of unsatisfied affection for parents and a response to feelings of unacceptance. Rejection sensitivity is particularly important in the Korean culture because of cultural factors.

Purpose: This study conducted a concept analysis of rejection sensitivity using the Walker and Avant method, to clarify its defining attributes, antecedents, and consequences. So, this contributes to a deeper understanding of its role in interpersonal relationships. Methods: Walker and Avant’s framework, this concept analysis included a thorough literature review across multiple disciplines. The literature was extracted from databases such as PubMed, Web of Science, CINAHL, and RISS. Results: Rejection sensitivity is a psychological construct encompassing several attributes, including rejection expectation, perception of rejection, and reaction to perceived rejection. This trait is influenced by various antecedents, including early life experiences, attachment style, and cultural factors. The consequences or events associated with rejection sensitivity span multiple domains and can significantly affect an individual’s life. Conclusion According to interpersonal psychology and attachment theory, problem behavior in adolescents is a state of unsatisfied affection for parents and a response to feelings of unacceptance. Rejection sensitivity is particularly important in the Korean culture because of cultural factors.

Purpose: The purpose of this study was to identify the relationships between resilience, social support, and body image in patients in an acute stage following traffic accidents and to investigate factors affecting body image. Methods: Data were collected from 86 patients at local hospitals from January 2019 to February 2020. To measure the variables, the body image scale, Conner-Davidson Resilience Scale, and Multidimensional Scale of Perceived Social Support were used. Data were analyzed using descriptive statistics, independent t-tests, analysis of variance, Pearson correlation coefficient, and multiple regression. Results: Mean age of participants was 43.40±14.75 and the proportion of men was 73.3%. The average score for resilience, social support, and body image were 65.16±16.89, 72.93±8.11, and 12.24±6.63, respectively. The highest item on the body image scale was “Are you dissatisfied with the appearance of your scar?”. There were differences in scores for body image according to gender, age, and living status. Resilience (r=-.68, p<.001) and social support (r=-.65, p<.001) were negatively correlated with body image. In the regression model, resilience (β=-.41), social support (β=-.30), and gender (β=.22) accounted for 57.6% of the variance in body image. Conclusion Resilience and social support were identified in this study as significant factors protecting body image of patients during the acute stage following a traffic accident. It is recommended that psychosocial nursing interventions be conducted throughout the course of treatment.

PURPOSE: This study aimed to assess the levels of and relationships among health literacy, knowledge about diabetes, and self-care activities in the Korean low-income elderly with diabetes and to identify factors influencing the self-care activities of this vulnerable population. METHODS: This study surveyed a total of 151 low-income elderly patients with diabetes registered at 16 Visiting Health Care Services in B City, Korea. Health literacy was measured with the Newest Vital Sign. Diabetes knowledge was measured with the Diabetes Knowledge Test. The Summary of Diabetes Self-care Activities Questionnaire was used to assess diabetes self-care activities. A stepwise multiple regression analysis was conducted to identify significant factors influencing diabetes self-care activities in these patients. RESULTS: In the regression model, diabetes knowledge (beta=.322, p<.001), exercise (beta=.337, p<.001), and experiences of diabetes education (beta=.241, p=.001) were significantly associated with increased diabetes self-care activities in low-income elderly patients with diabetes when gender, education, health literacy, and subjective health state were controlled. CONCLUSION: To improve diabetes self-care activities in the low-income elderly with diabetes, it is important to develop a customized program considering their knowledge, exercise, and diabetes education experience.
Aged ; Delivery of Health Care ; Diabetes Mellitus ; Education ; Health Education ; Health Literacy* ; Humans ; Korea ; Self Care* ; Vital Signs ; Vulnerable Populations ; Surveys and Questionnaires

The purpose of this study is was to compare the color stability of alkasite and other restorative materials commonly used in the field of pediatric dentistry and to study a color change in response to various beverages. Test specimens of glass ionomer, resin modified glass ionomer, alkasite restorative material, and composite resin were prepared, and the color stability was measured after thermocycling. Each specimen was also subdivided into 5 groups and submerged in PBS, coffee, green tea, coke, and orange juice to analyze the color change from the original CIE L*a*b* values after 7, 14, 21, and 28 days. Composite resin showed the best color stability after thermocycling, followed by alkasite restorative material, glass ionomer, and resin modified glass ionomer. Submerging in various beverages for 7 days resulted in color change in all test specimens, with alkasite restorative material showing less color change than glass ionomer but greater change than composite resin. Alkasite restorative material showed the greatest color change in coffee, followed by green tea and orange juice, but almost no change in coke and PBS even after 28 days of submersion.

PURPOSE: T cell-mediated immune responses, and particularly activation of polyfunctional T cells that simultaneously produce multiple cytokines, are necessary for the control of Mycobacterium tuberculosis. In the present study, we examined if DNA immunization of Mycobacterium tuberculosis resuscitation-promoting factor B (RpfB) elicits polyfunctional T cell responses in mice. MATERIALS AND METHODS: C57BL/6 mice were immunized intramuscularly three times, at 3-week intervals, with RpfB-expressing plasmid DNA. For comparison, protein immunization was performed with recombinant RpfB in control mice. After immunization, RpfB-specific T cell responses were assessed by interferon-gamma (IFN-gamma) enzyme-linked immunosorbent spot assay and intracellular cytokine staining (ICS), and T cell polyfunctionality was assessed from the ICS data. RESULTS: RpfB DNA immunization induced not only humoral immune responses, but also CD8+ and CD4+ T cell responses. Immunodominant T-cell epitopes were identified within RpfB by assays with overlapping peptides. RpfB DNA immunization elicited a polyfunctional CD8+ T cell response that was dominated by a functional phenotype of IFN-gamma+/TNF-alpha+/IL-2-/CD107a+. CONCLUSION: RpfB DNA immunization elicits polyfunctional CD8+ T cell responses, suggesting that RpfB DNA immunization might induce protective immunity against tuberculosis.
Animals ; Complement Factor B* ; Cytokines ; DNA* ; Epitopes, T-Lymphocyte ; Immunity, Humoral ; Immunization* ; Interferon-gamma ; Mice ; Mycobacterium tuberculosis* ; Peptides ; Phenotype ; Plasmids ; T-Lymphocytes ; Tuberculosis ; Vaccines, DNA

Cytomegalovirus (CMV) infection in healthy individuals is usually asymptomatic and results in latent infection. CMV reactivation occasionally occurs in healthy individuals according to their immune status over time. T cell responses to CMV are restricted to a limited number of immunodominant epitopes, as compared to responses to other chronic or persistent viruses. This response results in progressive, prolonged expansion of CMV-specific CD8+ T cells, termed 'memory inflation'. The expanded CMV-specific CD8+ T cell population is extraordinarily large and is more prominent in the elderly. CMV-specific CD8+ T cells possess rather similar phenotypic and functional features to those of replicative senescent T cells. In this review, we discuss the general features of CMV-specific inflationary memory T cells and the factors involved in memory inflation.
Aged ; Cytomegalovirus Infections* ; Cytomegalovirus* ; Humans ; Immunodominant Epitopes ; Inflation, Economic* ; Memory* ; T-Lymphocytes

No abstract available.
Base Sequence ; Bone Marrow/pathology ; Fusion Proteins, bcr-abl/*genetics ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis/*genetics ; Male ; Middle Aged ; Real-Time Polymerase Chain Reaction