Objective: To evaluate the significance of occlusion of hemihepatic inflow plus major ipsilateral hepatic veins in anatomic hepatectomy. Methods: One hundred and two cases were divided into 3 groups for anatomic hepatectomy: Group A (hemihepatic inflow plus major hepatic vein occlusion, n=42), Group B (hemihepatic inflow occlusion, n=30)and Group C (Pringle maneuver, n=30). The amount of intraoperative bleeding, time of operation, postoperative liver function, liver function recovering and complications were compared. Results: The average amount of hemorrhage in Group A, Group B and Group C were(453.5?87.9)、(612.8?101.6)and(646.7?136.6)mL, respectively. The mean blood loss in Group A was significantly more than that in Group B and Group C (P0.05). The levels of serum alanine transaminase (ALT)and bilirubin of 3rd and 6th day of postoperation in Group A and Group B were significantly lower than that in Group C, while the level of serum albumin in Group A and Group B was significantly higher than that in Group C(P0.05). Incidence of ascites in Group C was significantly higher than in Group A and Group B (P

Objective To observe the effect of Shoutaiwan on improving clinical pregnancy rate of in vitro fertilization-embryo transfer (IVF-ET). Method Eighty people, who were easy to be followed up and pregnant with the assistant of IVF-ET by the tube-baby centre of Shenzhen Urology Surgical Hospital of Zhongshan Medical University from 2001 to 2003, were divided into two groups randomly with 40 people for each. Treatment group, after embryo transfer, were normally injected progesterone and auxiliary treated of traditional Chinese Medicine according to syndrome differentiation. The comparing group were only injected progesterone. The curative effect was observed and compared. Result In 40 cases of treatment group, 23 cases were pregnant, clinical pregnant rate was 57.5%, the average level of progesterone was (22.45?1.31)?g/L, pregnant abortion rate was 13.0%. In 40 cases of comparing group, 12 cases were pregnant, clinical pregnant rate was 30.0%, the average level of progesterone was (10.18?0.89)?g/L, pregnant abortion rate was 25%. There were significant differences in the clinical pregnant statistical rate, the average level of progesterone and pregnant abortion rate between the two groups. Conclusion It’s more effective that the syndrome differentiation method based on Shoutaiwan than progesterone treatment only in improving clinical pregnant rate and reducing pregnant abortion rate of IVF-ET.

Transoral laser microsurgery (TLM) has developed more than 40 years in the treatment of laryngeal cancer. TLM is especially important in the minimally invasive surgery of laryngeal carcinoma. Compared with the traditional open surgery, it is a major breakthrough, which has the significant advantages such as safety, effectiveness, low rate of local recurrence and high rate of larynx preservation. Not only can cure early laryngeal cancer, but also more and more the use of TLM in advanced supraglottic and glottic laryngeal cancer were reported. This article will review the characteristics, indications, superiority, surgical options and efficacy of the TLM in laryngeal carcinomas.
Carcinoma, Squamous Cell ; Glottis ; Humans ; Laryngeal Neoplasms ; surgery ; Laryngectomy ; Laser Therapy ; Microsurgery ; Neoplasm Recurrence, Local ; Organ Sparing Treatments ; Otorhinolaryngologic Surgical Procedures

Objective To investigate the therapeutic effect of intra-arterial thrombolysis (IATT) in acute cerebral infarction(ACI). Methods 15 patients with ACI were treated with IATT using Urokinase(UK). All patients were assessed by DSA before and after IATT. The stroke scale(ESS and NIHSS) and Barthel Index(BI) were used before and 2 h,48 h,15 d ,30 d after treatment for appraising thearpeutic effect . Results After IATT, the sides of obliterated middle cerebral artery in 12 patients were completely re-circulated. Compared with before IATT, the scores of ESS, NIHSS and BI were significantly improvement at 2 h,48 h,15 d and 30 d after IATT(P

Objective To investigate the effect of Botulinum toxin type A(BTXA)and rehabilitation intervention on upper limb Brunnstrom stages and ADL performance of stroke patients. Methods In a randomized controlled trial, 30 patients were allocated to either an experimental group (n=15) that received BTXA injection into muscles of the affected arm or to a controlled group (n=15). All patients' Brunnstrom stage and MAS stage were ≥gradeⅡ. All the patients were treated with rehabilitative techniques. The intervention was applied for 3 months. All were evaluated for the severity of spasticity (Modified Ashworth Scale,MAS),the level of impairment (Brunnstrom assessment and Fugl-Meyer upper limb test) and disability(Functional Independence Measure,FIM) before and after 1 week, 1,2,3 months of treatment. Results Patients who received BTXA had significant reduction of muscle tone (P

Objective To study diffusion characteristic, diffusion-weighted imaging (DWI) technique and its value in lumbar osteolytic metastases. Methods Twenty patients with lumbar osteolytic metastases and 20 controls were performed with sagittal SE T_1WI, FSE T_2WI, fat saturation FSE T_2WI(FS-FSE T_2WI)and single-shot spin-echo echoplanar DWI, respectively. Contrast noise ratios (CNRs) of the metastases on various series were compared. On DWI, signal attenuation ratios (SARs) and apparent diffusion coefficients (ADCs) of lumbar osteolytic metastases and normal vertebrae were analyzed. Results (1) Routine MRI appearance: There were 23 lesions in the 20 patients. The signal intensity of all lesions showed hypointense on SE T_1WI, hyperintense on FS-FSE T_2WI and DWI, and mixed signal intensity (5 cases), isointense (12 cases) or slight hyperintense (6 cases) on FSE T_2WI. (2) CNR: The CNRs of patient group on FSE T_2WI(5.70?3.82)were lower than those on SE T_1WI(25.62?11.73), FS-FSE T_2WI(23.37?7.48)and DWI (b=600 s/mm2)(24.69?9.87)(U values were 5.393, 6.359, and 5.547, respectively,P

Objective:To evaluate the value of CT in the diagnosis of skeletal metastases from hepatoma.Methods:27 patients proved by clinical or pathological materials were analysed retrospectively.Results:All the lesion were osteolytic on CT scans.The most frequently involved areas were spine(26%),ribs(22%),pelvis(19%)and femur(11%).Conclusion:CT scan is superior to X-ray plain flims in showing the lesions.Most foci can be diagnosed accurately.

Objective To detect the changes in protein profile of rats'lung inhaled radon using two- dimensional electrophoresis(2-DE)and MS.Methods Male Wistar rats were exposed to radon with the cumulative dose up to 100,200 and 400 working level months(WLM).The total proteins of rats'lung were extracted and isolated by 2-DE.The different protein expressions were analyzed with ImageMaster 2D Platinum software and obviously altered proteins were digested by trypsin and identified by MALDI-TOF-MS.Resuits Comparison of the 2-DE images between the control and radon-exposed groups indicated 14 up-regulated and 9 down-regulated protein spots,15 of which were identified by MALDI-TOF or MALDI-TOF/TOF MS.Conclusions The 2-DE image of radon groups'lung has changed,and the lung damage effect of radon is related to some proteins.

BACKGROUND: The research group for the physical quality of minorities has performed the computer measurement of craniofacial organs in 15 minorities of Yunnan province, including Dai nationality, Yi nationality,Lagu nationality, Lisu nationality, etc., but those of Bulang nationality have not been conducted.OBJECTIVE: To completely and systematically measure the 41 items and 17 indexes of the craniofacial organs of Bulang minority in Bangbing countryside of Shuangjiang county in Lincang area.DESIGN: A cross-sectional study.SETTING: Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital of Kunming Medical College.PARTICIPANTS: From May to October in 2002, 155 subjects of Bulang nationality, who were of pure blood lineage of Bulang nationality, and the three generations before whose parents were all Bulang nationality, were selected from the Bangbing countryside of Shuangjiang county in Lincang area, and they all participated in the study voluntarity, including 96 males and 59 females, and the forms and functions of their cranial and maxillofacial organs were all normal.METHODS: The subject was asked to sit up straightly, the skull was fixed with skull retention instrument, the Frankfurt horizontal plane should be parallel to the cross section, and the measurement points were marked with pen; The craniofacial images of the subject were recorded with camera at a distance of 5 m, and the images were input to the computer for later use. The self-designed video-computer measure system was adopted to measure craniofacial indexes. Judgement standards for the observed items:Besides the tab stops for distance between lip peaks, unilateral lip length,height of palpebral opening, breadth of nasal septum and nostril breadth by Xu et al, and those for frontonasal angle, nasolabial angle and nose angle by Ma et al, that for height of upper eyelid was self-designed, and the other items all referred to the requirements in Manual of Anthropometry[3] and Methods of Anthropometry.MAIN OUTCOME MEASURES: ① Forty-one measurement items:minimal malar breadth, bizygomatic breadth, interocular breadth, interpupillary distance, breadth of palpebral opening, breadth of mouth opening,distance between lip peaks, single lip length, height of palpebral opening,physiognomic frontal height, physiognomic facial height Ⅰ, physiognomic facial height Ⅱ, morphological facial height, physiognomic facial height Ⅲ,upper physiognomic facial height, nose height, lip height, whole upper lip height, whole lower lip height, height of 1/3 inferior face, chin height,height of upper eyelid, nose breadth, breadth of nasal septum, nostril breadth, breadth between two angles of jaw, external ear width, nose length, nose depth, physiognomic ear length, physiognomic eat width, frontonasal angle, nasolabial angle, nose angle, maximal head breadth, width between two traguses, maximal head length, auricular height, total head height, horizontal head circumference; ② 17 craniofacial indexes: head length breadth, head length height, head breadth height, frontoparietal breadth, physiognomic face, morphological face, upper physiognomic face,nose index, nose breadth depth, mouth index, physiognomic ear, frontal height, upper facial height, width of malar lower jaw, malar frontal breadth,craniofacial height, craniofacial breadth.RESULTS: All the 151 subjects were involved in the analysis of results.① Measurement items of craniofacial organs: Only the values of physiognomic ear length and frontonasal angle were higher in females than in males, all the other items were higher in males than in females. The statistical analysis indicated that except the items of height of upper eyelid,breadth of nasal septum, physiognomic eat width, frontonasal angle, nose angle, width between two traguses, total head height and horizontal head circumference (P ＞ 0.05), the values of all the other items were significantly different between males and females. ② Indexes of craniofacial organs:Only the indexes of head length breadth, head breadth height, frontoparietal breadth, physiognomic face, morphological face, frontal height, width of malar lower jaw, malar frontal breadth, craniofacial height had no significant differences between males and females (P ＞ 0.05), and the others were significantly different between males and females.CONCLUSION: Most of the 41 measurement items of craniofacial organs were higher in males than in females among the Bulang minority in Bangbing countryside of Shuangjiang county in Lincang area, and most of the 17 indexes of craniofacial organs have no significant differences.

OBJECTIVETo study the types of matrix metalloproteinases (MMPs) involved in dentin bonding interface degradation.

METHODSDentin slices were prepared and treated with two adhesive systems (Single Bond 2 or Clearfil S3 Bond). The dentin surface was bonded with composite resin. All specimens were immersed in sterile artificial saliva for 0 or 6 months, and their micro-shear bond strength (muSBS) were measured. The fracture modes were observed through field emission scanning electron microscope (FE-SEM). Dentin slices with 4 mm x 3 mm x 1 mm dimensions were prepared. The slices were divided into three groups according to the treatment modes (negative control, Single Bond 2, and Clearfil S3 Bond). All specimens were stored in sterile artificial saliva for 0 or 6 months. The concentrations of MMP-1, -2, -3, -8, and -9 of each group were detected through fluorescent microsphere immunoassay.

RESULTSThe muSBS of both adhesive systems significantly decreased after storage aging. Significant differences in failure modes within the four groups tested in this study were observed. Compared with the negative control, the concentrations of MMP-1 and MMP-3 in different adhesive groups showed no significant difference after storage aging. However, the concentrations of MMP-2, -8, and -9 in Single Bond 2 group and the concentrations of MMP-8 and -9 in Clearfil S3 Bond group significantly decreased after 6 months of storage aging.

CONCLUSIONSignificant degradation occur in the dentin bonding interface of both adhesive groups under 6 months aging challenge. The concentrations ofdentinal MMP-2, -8, and -9 significantly decrease after treatment with adhesives and aging, indicating that these MMPs have an important function in dentin bonding interface degradation.