1.To observe the effect of threatened abortion after 20 weeks of treatment of pregnancy psychological intervention combined with ritodrine hydrochloride and Magnesium Sulfate
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):314-315
Objective To study the psychological intervention combined with ritodrine hydrochloride and observe the effect of Magnesium Sulfate threatened abortion after 20 weeks of treatment. Methods 100 pregnant women with threatened abortion in our hospital from February 2015 to October 2016 were selected and randomly divided into control group and experimental group. Each group had 50 cases. the control group was treated with Magnesium Sulfate treatment, experimental group was treated with ritodrine hydrochloride treatment, psychological intervention, pay attention to mental health, strengthen the communication with patients. Results After the corresponding treatment, the SAS score of the experimental group was (40.1±6.2) points, and the SDS score was (38.4±7.9) points. The scores of SAS and SDS in the control group were (49.6±7.2) points, (48.2±8.5) points. After treatment, 5 patients in the experimental group had adverse reactions, and the incidence of adverse reactions was 10%. Adverse reactions occurred in 13 patients in the control group. The adverse reaction rate in the control group (26.0%) was significantly higher than that in the experimental group (10.0%), with statistical difference (P<0.05). The weight of the newborn, the duration of pregnancy and the onset time of the drug in the experimental group were better than those in the control group (P<0.05). Conclusion Psychological intervention combined with ritodrine hydrochloride and Magnesium Sulfate have good clinical effect on the treatment of threatened abortion after 20 weeks of gestation, can visibly improve patients' depression and anxiety, with further clinical promotion and application significance.
2.Research progress in Lamins in malignant tumors.
Haixiao DENG ; Zeyuan YU ; Jihe KANG ; Junjie QIN ; Xiangyan JIANG ; Zuoyi JIAO
Journal of Central South University(Medical Sciences) 2020;45(12):1490-1498
Changes in nuclear morphology are common in malignant tumors, but the underlying molecular mechanisms remain poorly understood. Lamins is involved in supporting nuclear structure, and the expression of Lamins is the molecular basis for nuclear morphological changes during tumor progression. In recent years, the research on the relationship between Lamins and malignant tumors has made great progress. Lamins is of great value in the diagnosis, treatment, and prognosis of various malignant tumors.
Cell Nucleus
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Humans
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Lamins/genetics*
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Neoplasms/genetics*
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Prognosis