Objective To investigate and study the role of clinical pharmacists in controlling the antibiotics use density (AUD) indicators. Methods Pharmaceutical services were conducted by clinical pharmacists through basic data survey, participation in developing hospital AUD indicators, regular monitoring and analysis, proposal of individualized rectifi-cation recommendations specific to various clinical departments, enhancement of antibiotics prescription comment, or-ganization of training on rational antibiotics use, etc. Results The AUD indicators of our hospital reduced largely and the AUD value had been controlled under 40DDDs since the second half of 2013. Conclusion Clinical pharmacists can give full play to their advantages, propose rational recommendations and effectively reduce the hospital AUD value from the aspect of pharmacy.