1.?-interferon in the treatment of renal cell carcinoma after radical nephrectomy
Wei ZHU ; Jiexin FU ; Jianan LI
Chinese Journal of Urology 2001;0(06):-
Objective To study the effect of ? interferon in the treatment of renal cell carcinoma after radical nephrectomy. Methods From Jan 1988 to Jan 1998 ,46 cases of renal cell carcinoma were randomized into two groups: the interferon group treated by radical nephrectomy and ? interferon and the control group with radical nephrectomy alone. Results The T lymphocyte subsets CD 3,CD 4,CD 8,the ratio of CD 4/CD 8 were significantly different berfore and after treatment in the interferon group( P
2.Volume of residual urine as an indication for surgical treatment of benign prostatic hyperplasia
Wei ZHU ; Jiexin FU ; Jianan LI
Chinese Journal of Urology 1994;0(02):-
Objective To study the volume of residual urine as related to the surgical indication for BPH. Methods Urodynamic study was carried out in 103 BPH patients who were assigned to group A (no residual urine),group B (residual urine0.05) but significantly different between group C and A or between B and A (P60 ml should be strictly followed.Early surgical intervention should be undertaken if the bladder ontlet obstruction or bladder function deteriorated by BPH causing residual uine.Other causes such as neurogenic should be ruled out before surgery.
3.Postoperative usage of α-interferon in the treatment of renal cell carcinoma
Wei ZHU ; Jiexin FU ; Jianan LI ; Bochuan CHEN ; Gang YI
Journal of Clinical Urology 2001;16(6):261-262
Purperse:To study the effect of α interferon in the treatment of renal cell carcinoma after radical nephrectomy.Methods:From Jan 1988 to Jan 1998,46 cases of renal cell carcinoma were randomized into two groups: the study group were treated by radical nephrectomy and α-interferon while the control group with radical nephrectomy alone.Results:The T lymphocyte subsets CD3,CD4,CD8,the ratio of CD4/CD8 are significantly different berfore and after treatment in the study group (P<0.05); the 3 year(90.5%) and 5 year (89.5%) survival rate in patients of the study group are higher than that of the control group (P<0.05).Conclusions:α-interferon therapy after radical nephrectomy can restore celluar immunity so as to enhance the treatment efficacy.
4.A comparative study of the curative effects between butterfly-shaped flap and propeller flap based on the dorsal branch of digital artery in repairing the wound in volar aspect of finger
Xu SUN ; Zongqi YIN ; Jiexin ZHENG ; Yi DOU ; Qin ZHANG ; Qiang FU ; Wenlong ZHANG ; Lei YI
Chinese Journal of Burns 2023;39(6):552-557
Objective:To compare the curative effects of butterfly-shaped flap based on the dorsal branch of digital artery (hereinafter referred to as butterfly-shaped flap) and propeller flap based on the dorsal branch of digital artery (hereinafter referred to as propeller flap) in repairing the wound in volar aspect of finger.Methods:A retrospective cohort study was conducted. From August 2018 to April 2022, 16 patients with finger palmar wounds admitted to Ruijin Hospital of Shanghai Jiao Tong University School of Medicine and 7 patients with finger palmar wounds admitted to General Hospital of PLA Central Theater Command met the inclusion criteria, including 14 males and 9 females, aged 25 to 64 years. After debridement or resection of skin benign tumor, the wounds ranged from 0.5 cm×0.5 cm to 1.5 cm×1.5 cm. According to the different rotation axes of flap pedicle during wound repair, the patients were divided into butterfly-shaped flap group (8 cases) and propeller flap group (15 cases), and their wounds were repaired by butterfly-shaped flap (with area of 0.5 cm×0.5 cm-1.5 cm×1.3 cm) or propeller flap (with area of 0.7 cm×0.5 cm-1.5 cm×1.5 cm) , respectively. In propeller flap group, wounds in the donor sites were repaired by full-thickness skin grafts taken from the palms of wrists or the groin. The surgical time, postoperative complications, flap survival, and wound healing time of patients in the two groups were recorded. Data were statistically analyzed with independent sample t test, Mann Whitney U test, or Fisher's exact probability test. Results:The surgical time and postoperative wound healing time of patients in butterfly-shaped flap group ((43±9) min and (13.1±0.8) d, respectively) were both significantly shorter than those in propeller flap group ((87±16) min and (16.7±4.6) d, respectively, with t values of -7.03 and -2.86, respectively, P<0.05). The postoperative flap survival and complications of patients between the two groups were both similar ( P>0.05). Conclusions:For repairing the wound in volar aspect of finger, the butterfly-shaped flap has more advantages in comparison with the traditional propeller flap. The butterfly-shaped flap has a short surgical time and fast postoperative recovery, which is worthy of clinical promotion.