Interdisciplinary research is one of the focus of sci-entific method discussion .In recent years a large number of interdiscipli-nary methods or engaged in interdisciplinary research and collaboration between scientists have won the Nobel prize , once again proved this point.Its profound, interdisciplinary research in the field of medicine it-self also embodies a new paradigm of modern medical science and explo-ration the cross disciplinary research applied to medical postdoctoral training work, aims to cultivate a group of clinicians is an excellent ex-perimental research and know the innovative medical amphibious expert.With the development of modern medicine and the current actual situation , the development of a single subject is far from enough .This article from the interdisciplinary talents cultivation idea or-igin, development of surgery and anatomy , informatics, imaging, such as the development of other disciplines and the close connection between the hot research in twenty-first century To expound the progress of medicine , the need for mutual cooperation between families , and by their respective areas of strengths together to carry out interdisciplinary research .

Chemotherapy has been shown to be effective in the treatment of patients malignancies, however, anticancer drugs, particularly high-dose, also damage other chemosensitive tissues such as the intestinal mucosa, and these adverse effects can impair intestinal mucosal barrier. The derangement in the barrier function plays a central role in the pathophysiology of systemic infection, shock, and sepsis syndrome. The chemotherapy-induced intestinal barrier dysfunction and its prevention and treatment had been reviewed.

Tertiary peritonitis is manifested by immunodeficiency and serious diseases which is different with secondary and primary peritonitis. It is a complex nosocomial infection in surgical patients. The pathogenesis, clinical features, diagnosis and treatment of tertiary peritonitis is reviewed.

Organ transplantation is the treatment of choice for patients with end stage organ disease, many organ transplant patients with malnutrition are at high risk for developing postoperative complications, and causing death. Nutritional support can improve outcome of organ transplant patients.

Critical care medicine is an emerging unique specialty developed from the later 20th century,since then,it has been enriched with theoretical and practical experiences and becomes the most active subject in the field of clinical medicine.Critical care medicine of the PLA has attained significant achievements in the treatment and research of severe trauma,sepsis,severe heat stroke,multiple organ failure and severe acute pancreatitis.Besides,it stands in the leading position in the organ function maintenance of critically ill patients,continuous hemofiltration and nutrition support in China.Furthermore,critical care medicine plays an important role in the rescue of critically ill patients,medical support and disaster relief.As the relationship between battle wound rescue system and critical care medicine has been increasingly close,transition in the form of war in the new period brings new tasks to battle wound treatment constantly.Combined with the characteristics of information-oriented war condition in the future,developing the PLA critical care medicine and advancing the level of battle wound treatment in the new period point out the direction for the future work of critical care medicine.

Colorectal cancer is a very common malignant neoplasm.It is widely accepted that community screening for colorectal cancer significantly reduces mortality of this disease.Detection of neoplasm is facilitated by fecal occult blood testing(FOBT),sigmoidoscopy,colonoscopy and double contrast barium enema.Colonoscopy is currently the gold standard,however,the appropriate age to begin testing and time interval between repeat sereenings remain unclear.Screening with CT colonography(vivtul colonoscopy),fecal DNA analysis and detecting cyclooxygenase 2 messenger RNA in feces is under study.Finding the optimal screening method and increasing acceptability to both physician and patients remain to be studied further.

Objective:To evaluate the effect of enteral rehabilitative therapy in improving graft structure recovery in rat small bowel transplantation.Methods:Fourty eight recipients of rat allogeneic heterotopic small bowel transplantation(SD→Wistar rat)were dvided into 4 groups randomly according to the presence or absence of glutamine or rhGH in TPN regimen.Cyclosporine A was used as the immunosuppressant.The morphological mucosal indices of transplanted gut were observed and compared.Results:The application of rhGH and glutamine-enriched TPN,especially the enteral rehabilitation therapy which composed both these two agents,can promote the recovery of graft structure significantly compared with standard TPN support.On the postoperative day 14,in the enteral rehabilitation therapy group,all the morphological indexes of transplanted gut recovered to the preoperative state.Conclusion:Enteral rehabilitation therapy is appropriate to the host metabolic status,so it can improve the graft structure recovery more effectively.

The study compared the effects of the branched-chain amino acid enriched solution with standard.amino acid solution on patients during early postoperative period.Sixteen patients who underwent mode 時ate abdominal operative procedures were divided into study (BCAA) and control groups randomly.Either group of patients received equal amount of nitrogen (0.2g/kg d-1) and energy(l46-167kJ/kg d-1) during the first five postoperative days.Recommended doses of other nutrients were added daily.Nitrogen balance was detemined every day postoperatively.Plasma albumin,fibronectin and amino acid profile as well as other parameters were monitored preoperatively and on 3rd and 6th postoperative days.The results suggested that the nutritional effects of the branched-chain amino acid enriched solution might be superior to that of the standard nutritional amino acid solution on postoperative patients.

Multiple organ failure (MOF) is a severe complication induced by intra-abdominal sepsis (IAS) in surgical patients. The study was planned to evaluate the role of metabolic support with different formulas of nutrient substants in 42 rabbits of MOF model which was establishei before. The results showed that metabolic support in the early stage of MOF induced by IAS coul increase body weight in varying degree, promote protein synthesis and decrease protein degration in rabbits. Lower non-protein calorie supplied with glucose might decrease stress response, increase nitrogen retention and improve lung function. Overloads of amino acid nitrogen could increase stress response, increase urinary nitrogen excretion and deteriorate the respiratory function.

The role of polyunsaturated fatty acids (PUFAs) in inflammatory diseases is the subject of increasing research. This review is focused on the role in the immune system including lymphocytes, neutrophils, NK cells and monocytes. The available data and hypotheses as to the manipulation of PUFAs in immune cells are reviewed. Possible mechanisms include alterations in membrane fluidity, eicosanoid synthesis, signal transduction, gene expression and apoptosis.