Chuanxiong Rhizoma,the dried rhizome of Ligusticum chuanxiong Hort.(Umbelliferae),has the effects of ac-tivating blood,promoting the circulation of Qi,dispelling pathogenic wind,and relieving pain.Chuanxiong Rhizoma contains phthalides,alkaloids,phenolic acids,and polysaccharides.Pharmacological research indicates that Chuanxiong Rhizoma has various pharmacological activities on the cardiovascular system,nervous system,and respiratory system,which are mainly manifested as anti-cerebral ischemia,anti-thrombosis,analgesia,anti-inflammation,antioxidation,and anti-asthma effects.In this paper,the chemical constituents and pharmacological effects of Chuanxiong Rhizoma are systematically summarized in order to provide references for its clinical application and resource development.

Rehmannia glutinosa,belonging to the genus Rehmannia(family Scrophulariaceae),is a widely used Chinese medical herb that is included in the list of medicine and food homology substances in China.First described in Shennong's Classic of Materia Medica,it has been widely used clinically now.Mainly produced in Henan,Hebei,Shandong and Shanxi,the Rehmannia glutinosa in Huaiqing Prefecture(an ancient administrative district)of Henan is the most authentic,and it is listed as one of the four famous Chinese herbs produced in the Huaiqing area.In recent years,with the comprehensive and in-depth study of Rehmannia glutinosa by scholars at home and abroad,its diverse chemical constituents,extensive pharmacological actions,development and application have attracted much attention.In this paper,the relevant literature on the main chemical constituents and pharmacological activities of Rehmannia glutinosa is reviewed,in order to provide references for related research.

Clinical trial is an important step of in vitro diagnostic reagents research and development. Based on the Guiding Principles and the key points of inspect on the spot, combined with the actual work experience, the article focuses on the prominent problems in the whole process of in vitro diagnostic reagent clinical trials. It is helpful to improve the level of hospital drug clinical trial centre and the quality of in vitro diagnostic reagent clinical trials by analyzing the issues.
Clinical Trials as Topic ; Indicators and Reagents/administration & dosage* ; Reagent Kits, Diagnostic