7 layers).Mito tic figures are infrequent and usually limited to the basal layer.C onclusionsPUNLMP is not associated with invasion or metastases and should be treated locally.However,long term clinical follow-up is warranted.

Objective:To investigate the mental health status and related influencing factors of medical staff in a tertiary Traditional Chinese Medicine(TCM)hospital during COVID-19 normalized prevention and control period.Methods:In March 2021, the medical staff of a TCM hospital in Beijing were investigated by general information questionnaire, self-rating anxiety scale(SAS), self-rating depression scale(SDS) and 12-item general health questionnaire(GHQ-12). Descriptive analysis, single factor analysis, and logistic regression analysis were preformed by using SPSS 22.0 software.Results:A total of 872 medical staff accepted this survey and 869 valid questionnaires were collected. The total scores of SAS and SDS of medical staff in the hospital were significantly lower than those of medical staff in similar domestic study before the outbreak of COVID-19( P<0.001). The detection rates of anxiety symptoms, depression symptoms and mental health problems were 22.2%(193 cases), 27.8%(242 cases)and 12.5%(109 cases), respectively. There were significant differences in total scores of SAS, SDS and GHQ-12 in education levels, occupation, basic diseases, mental illness and family financial difficulties( P<0.05), and the total scores of SAS and SDS were significantly different in terms of working years( P<0.01). Binary logistic stepwise regression analysis showed that those with mental illness and family financial difficulties were at significantly higher risk of anxiety, depression, and mental health problems( P<0.001), those with low educational level had a significantly higher risk of anxiety and depression( P<0.05), and those with basic diseases had a significantly higher risk of depression( P=0.009). Conclusions:During COVID-19 normalized prevention and control period, some medical staff in the hospital had anxiety, depression and mental health problems with various degrees. More attention should be paid to those with bachelor′s degree or below, nurses and other healthcare staff, senior staff, people with basic diseases, mental illness, and family financial difficulties.

More and more clinical research projects are carried out in research hospitals.Through the multi-angle and whole-process quality control of the clinical research conducted by the research hospitals,including pre-project establishment,implementation,and post-completion,it can timely identify risks or potential risk factors in the clinical research,evaluate and solve quality problems in real-time,and avoid the possibility of major clinical research problems.Through whole-process quality control,research hospitals identify problems timely and proactively,establish coordination mechanisms,optimize the communication process,reduce the occurrence of research project quality problems,continuously improve the quality management systems of clinical research,ensure that research is compliant,data is complete and accurate,as well as improve the reliability of research conclusions.

Medical ethics ward rounds truly embody the behavior of respecting human nature and providing humanistic care for patients, which is conducive to the unity of medical scientific judgment and decision-making with medical ethical judgment and decision-making, and the integration of medical ethics and medical skills. Medical ethics ward rounds focus on both doctors and patients. Through reviewing medical records and medical-related documents, interviewing medical staff as well as patients, observing doctor-patient communication, the ward environment and facilities, etc., the medical ethics ward round team conducted comprehensive ethical ward rounds on the clinical departments of the hospital, and evaluated the actual situation of them in terms of patients’ informed consent, privacy protection, application of new clinical technologies, medical quality, ward environment and facilities, professional dedication of medical staff, and so on. The respect of medical staff for the rights and interests of patients is not only the respect for the basic personality of patients, but also the external embodiment of bioethics. Medical ethics ward rounds combined with the PDCA cycle can understand the pain points and difficulties in diagnosis and treatment, as well as the experience of patients in the process of medical treatment, and construct a harmonious doctor-patient relationship through the joint efforts of both doctors and patients.