1.Using Bank Reconciliation to Check the Accounts
Chinese Health Economics 2013;(12):108-109
Many units use automatic financial reconciliation software now , but the automatic financial reconciliation software often have some errors, which needs to be manually adjusted on the basis. According to the bank reconciliation, analyze data of each column of the specific analysis to confirm the authenticity of these deposit in transit , hoping to discuss a method of skillfully using bank balance adjustment table fast manual reconciliation.
2.Molecular classification of breast cancers.
Xiao-Song CHEN ; Shu-Jie CHEN ; Kun-Wei SHEN
Chinese Journal of Oncology 2008;30(9):641-643
Breast Neoplasms
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classification
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genetics
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metabolism
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pathology
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Female
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Gene Expression Profiling
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Gene Expression Regulation, Neoplastic
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Homeodomain Proteins
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metabolism
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Humans
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Neoplasm Invasiveness
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Neoplasm Recurrence, Local
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Oligonucleotide Array Sequence Analysis
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methods
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Receptors, Interleukin
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metabolism
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Signal Transduction
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Survival Rate
3.Role of contrast-enhanced ultrasound for preoperative detection of colorectal liver metastases-compared with histopathologic results
Jie WU ; Shanshan YIN ; Kun YAN ; Wei WU ; Minhua CHEN
Chinese Journal of Ultrasonography 2012;21(8):683-686
Objective To evaluate the role of contrast-enhanced ultrasound (CEUS) for preoperative detection of colorectal liver metastases.Methods 42 consecutive patients with colorectal liver metastases confirmed by histopathology after surgery were recruited in the study.They all had undergone preoperative CEUS examination with contrast agent SonoVue.The number,location and size of the hepatic lesions found by CEUS were correlated with postoperatively histopathologic results on a lesion-by-lesion basis.Results 96 liver metastases in 42 patients with colorectal cancer had been resected and confirmed by histophathology.The size of the metastatic lesions ranged from 0.3~8.5 cm [average (2.6 ± 1.8)cm].From one to eight metastatic lesions were detected in one patient.21 (21.9%) metastatic lesions were equal to or less than 1.0 cm.86 of 96 metastatic lesions were correctly depicted by CEUS,with a sensitivity of 89.6%.And the sensitivity for metastatic lesions equal to or less than 1.0 cm was 71.4% (15 of 21 tumors) by CEUS.35 metastatic lesions were found between the portal venous phase and late phase by CEUS and 19 (54.3%) metastatic lesions among them could not be detected at conventional ultrasound.The curative resection was performed in 37 (88.1%) of 42 patients.With 3 - 39 months follow-up,the intrahepatic recurrence rate within two years was 32.4% (12 of 37 patients) and the one-year survival rate was 90.0%.Conclusions CEUS is highly sensitive for detecting liver metastases resulted from colorectal cancer,especially for small metastatic lesions.CEUS is helpful to choose reasonable therapeutic strategies and can be regarded as one of the most importantly and noninvasively preoperative imaging modalities.
4.Effects of gastrin 17 and pepsinogen on anastomotic ulcer after gastric bypass surgery for resection of pyloric antrum
Jie LI ; Yan SUN ; Wei SU ; Kun CHEN ; Chengzhe SUN
Tianjin Medical Journal 2017;45(9):965-968
Objective To study the changes of gastrin 17 (G17) and pepsinogen (PG) after gastric bypass surgery in gastric antrum resection, and the influences of different surgical methods on postoperative peptic ulcer. Methods Clinical data of 63 patients with gastric bypass surgery in our hospital from October 2013 to October 2015 were divided into resection of pyloric antrum group (n=33) and preserved pyloric antrum group (n=30). The values of G17, PGⅠ, PGⅡand PGⅠ/PGⅡwere detected by enzyme linked immunosorbent assay at 1 month, 6 months and 12 months after operation. The correlation between the different surgical methods and the incidence of peptic ulcer was analyzed between two groups. Results The G17 levels were significantly decreased in resection of pyloric antrum group 6 and 12 months after operation than those in preserved pyloric antrum group (P<0.05). Compared with preserved pyloric antrum group,PGⅠ and PGⅡ levels was significantly decreased 12 months after operation (P<0.05). There was no significant difference in the ratio PGⅠ/PGⅡat 1 month, 6 months and 12 months after operation between two groups (P>0.05). There was no significant difference in postoperative peptic ulcer between two groups (P>0.05). Conclusion Gastric bypass after resection of the pyloric antrum can reduce the postoperative secretion of G17, PGⅠ and PGⅡ, but which can not reduce the incidence of postoperative anastomotic ulcer.
5.Effects of estrogen on expression of P2X7 receptor and neuroinflammation after subarachnoid hemorrhage in rats
Xiaoyu XU ; Hui CHEN ; Ping CHEN ; Kun WANG ; Jie GAO ; Liqian SUN
Chinese Journal of Immunology 2015;(11):1472-1475
Objective:To investigate the effect of estrogen on the expression of P2X7 receptor ( P2X7R) in the cerebral cortex and neuroinflammation after subarachnoid hemorrhage ( SAH) in rats.Methods:The rat model of SAH was induced by modified mono-filament puncture method.Sixty male SD rats were divided randomly into three groups:sham group;SAH group and estrogen-treatment group.The local cerebral blood flow was detected with laser doppler blood flow meter.The content of tumor necrosis factor alpha ( TNF-α) and interleukin-6 (IL-6) were measured by ELISA analysis.The expression of P2X7R in the cerebral cortex was tested by immuno-histochemical and Western blot methods.Results:Compared with that in Sham group,cerebral blood flow was significantly decreased after SAH (P<0.05),the content of TNF-αand IL-6 in the cerebral cortex were significantly up-regulated at each time point after SAH (P<0.05),peaked at 24 h,and the expression of P2X7R significantly increased at 6 h,12 h and 24 h after SAH (P<0.05),peaked at 12 h.Compared with that in SAH group,cerebral blood flow was significantly increased in estrogen-treatment group (P<0.05),the levels of TNF-α,IL-6 and P2X7R were down-regulated in estrogen-treatment group ( P<0.05).Conclusion: Estrogen could attenuate neuroinflammation in the cerebral cortex after subarachnoid hemorrhage in rats, which may be associated with the down-regulation in P2X7R proteins.
6.Study on Compatibility of TCM Prescriptions for Treating Alzheimer Disease Based on Data ;Mining
Sen LIN ; Jie LU ; Kun SONG ; Zongfu CHEN ; Sen JIANG ; Chunliang PAN ; Xuebo LI ; Xianjun FU
Chinese Journal of Information on Traditional Chinese Medicine 2015;(5):41-44
Objective To study the compatibility of TCM prescriptions of TCM practitioners of all dynasties of Alzheimer disease (AD). Methods Amnesia, forgetting, dementia, and idiot were set as search words to retrieve relevant literature in Encyclopadia of Traditional Chinese Medicine. Prescription information was screened and standardized to build database. Frequency analysis and association rules were used to mine TCM prescriptions and compatibility rules. Results Totally 449 AD related prescriptions were selected, involving 682 Chinese medicinal herbs. The individual herb with the highest frequency was Ginseng Radix Rhizoma (192);the herbal pair with the highest frequency was Ginseng Radix Rhizoma-Polyhalae Radix (182);the herbal combination with 3 Chinese medicinal herbs with the highest frequency was Poria with Hostwood-Ginseng Radix Rhizoma-Polyhalae Radix (79);the herbal combination with 4 Chinese medicinal herbs with the highest frequency was Polyhalae Radix-Ginseng Radix Rhizoma-Poria with Hostwood-Glycyrrhizae Radix et Rhizoma (37). The results of association rules showed that Ginseng Radix Rhizoma-Polyhalae Radix, Ginseng Radix Rhizoma-Glycyrrhizae Radix et Rhizoma, and Ginseng Radix Rhizoma-Poria with Hostwood were commonly used compatibilities in AD related prescriptions. Conclusion Treatment of TCM practitioners in all dynasties for AD mainly chooses Chinese medicinal herbs with the efficacy of tonifying qi and soothing nerves. The compatibilities and combinations are reasonable and with certain representativeness.
7.Effects of gender on incidence of intraventricular hemorrhage in very low and extremely low birth weight infants
Si CHEN ; Su LIN ; Hao ZHANG ; Qingqing JIE ; Kun SHANG ; Li WANG ; Zhenlang LIN
Chinese Journal of Perinatal Medicine 2014;17(5):317-322
Objective To examine the relationship between gender and intraventricular hemorrhage (IVH) in very low birth weight infants (VLBWI) and extremely low birth weight infants (ELBWI).Methods From January 1,1999 to December 31,2012,data on VLBWI and ELBWI,who were admitted to the neonatal intensive care unit of Yuying Children's Hospital within 14 d after birth,were retrospectively collected.The Chi-square test and t test were used to compare neonatal outcomes between male and female infants.The Logistic model was used to analyze the risk factors for IVH.Results A total of 1 008 cases were enrolled,including 615 males and 393 females,895 VLBWI and 113 ELBWI.The incidence of IVH was 15.1% (152/1 008) and the incidence of severe IVH was 8.4% (85/1 008).Compared with females,males had a higher total incidence of IVH [17.2% (106/615) vs 11.7% (46/393),x2=5.728,P<0.05] and severe IVH [9.8% (60/615) vs 6.4% (25/393),x2=3.896,P<0.05].These differences were also seen in VLBWI with a birth weight of 1 250 to 1 499 g [IVH:13.7% (47/344) vs 7.8% (17/217),x2=4.473,P=0.034; severe IVH:7.6% (26/344) vs 2.8% (6/217),x2=5.684,P=0.017].Logistic regression analysis showed that the risk factors for IVH were as follows:gestational age <28 weeks (aOR=2.012,95%CI:1.288-3.143,P<0.05),neonatal respiratory distress syndrome (aOR=l.584,95%CI:1.007-2.492,P<0.05),invasive mechanical ventilation (aOR=2.743,95%CI:1.826-4.121,P<0.05),electrolyte disturbance (aOR=2.128,95%CI:1.092-4.149,P<0.05) and periventricular leukomalacia (aOR=2.901,95%CI:1.312-6.416,P<0.05),but not male sex (aOR=1.351,95%CI:0.917-1.991,P=0.128).The risk factors for severe IVH were gestational age <28 weeks (aOR=2.200,95%CI:1.305-3.708,P<0.05),invasive mechanical ventilation (aOR=4.714,95%CI:2.809-7.911,P<0.05) and electrolyte disturbance (aOR=2.232,95%CI:1.047 4.759,P<0.05),but not male sex (aOR=1.361,95%CI:0.823 2.252,P=0.247).Conclusions Male VLBWI and ELBWI have a higher incidence of IVH and severe IVH,but male sex is not a risk factor for IVH or severe IVH.
8.Application value of contrast - enhanced ultrasonography in managing liver metastases before percutaneous radiofrequency ablation treatment
Wei WU ; Jie WU ; Jinyu WU ; Kun YAN ; Wei YANG ; Jungchieh LEE ; Zhongyi ZHANG ; Minhua CHEN
Journal of Interventional Radiology 2014;(6):487-490
Objective To assess the value of contrast-enhanced ultrasonography (CEUS) before percutaneous radiofrequency ablation (RFA) in treating patients with liver metastases. Methods A total of 267 patients with 485 liver metastatic lesions were treated with percutaneous RFA in authors ’ department during the period from July 2001 to December 2012. Among them , 180 patients with 251 lesions received CEUS examination before RFA and based on CEUS findings the treatment scheme was made (CEUS group), and other 87 patients with 234 lesions without use of preoperative CEUS were used as control group. No significant differences in clinical data existed between the two groups (P<0.05). Contrast-enhanced CT/MRI, CEUS and laboratory tests were regularly employed to evaluate the clinical results after RFA therapy. Results In CEUS group, 25.1% of the lesions (63/251) determined by CEUS were 3 mm larger than that determined by conventional US. 8.8%of the lesions (22/251) were more clear on CEUS findings. In addition, 41 new lesions were detected only on CEUS. No significant differences in early tumor necrosis rate existed between the two groups: 95.2%(239/251) vs. 92.7%(217/234)(P>0.05). The local recurrence rate of CEUS group was lower than that of the control group: 12.4% (46/234) vs. 19.7%(31/251) (P < 0.05). No significant differences in the recurrence time existed between the two groups (P > 0.05). Conclusion CEUS performed before RFA treatment for patients with liver metastases is very useful for accurately judging the size and number of the lesions, which is very helpful in making therapeutic scheme. Therefore, preoperative CEUS can significantly increase early tumor necrosis rate and decrease the local recurrence rate.
9.Chemical constituents from Chenopodium ambrosioides.
Kun SONG ; Hong-Qing WANG ; Chao LIU ; Jie KANG ; Bao-Ming LI ; Ruo-Yun CHEN
China Journal of Chinese Materia Medica 2014;39(2):254-257
Twelve compounds were isolated from the herb of Chenopodium ambrosioides, and their structures were identified by spectroscopic methods as kaempferol-7-O-alpha-L-rhamnopyranoside (1), kaempferol-3,7-di-O-alpha-L-rhamnopyranoside (2), patuletin (3), quercetin-7-O-alpha-L-rhamnopyranoside (4), grasshopper ketone (5), 4-hydroxy-4-methyl-2-cyclohexen-1-one (6), syringaresinol (7), benzyl beta-D-glucopyranoside (8), dendranthemoside B (9), N-trans-feruloyl tyramine (10), N-trans-feruloyl 4'-O-methyldopamine (11), and 4-hydroxy-N-[2-(4-hydroxyphenyl) ethyl] benzamide (12). Among them,compounds 3, 6-8,10, and 12 were isolated from the genus Chenopodium for the first time, and compounds 2-12 were isolated from this plant for the first time.
Chenopodium ambrosioides
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chemistry
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Drugs, Chinese Herbal
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chemistry
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isolation & purification
10.Detection of hepatic metastases by contrast-enhanced ultrasound compared with conventional ultrasound and contrast-enhanced computed tomography
Wenying LIU ; Kun YAN ; Shanshan YIN ; Wei YANG ; Ying FU ; Jie WU ; Minhua CHEN
Chinese Journal of Ultrasonography 2012;21(5):401-404
Objective To evaluate the role of contrast-enhanced ultrasound (CEUS) on the the detection of hepatic metastases in comparison with conventional ultrasonography (US) and contrastenhanced computed tomography (CECT).MethodsNinety-seven patients with hepatic metastases underwent US,CEUS and CECT images.Their detection of hepatic metastases were compared.Results Hepatic metastases showed five enhancement patterns with CEUS,including bolus hyper-enhancement,peripheralrimenhancement,inhomogeneousenhancementwithnecrosis,hypo-enhancement,isoenhancement with liver parenchyma,all hepatic metastases showed dark defects in portal and delayed phase.The mean number of metastases at CEUS was greater than that of US (2.6±1.9 vs 1.6 ±1.2,P<0.05).The detection of hepatic metastases was 53.4% and 87.1% respectively(P<0.05).CEUS and CECT have no statistically significant difference in the detection of hepatic metastases (P>0.05).ConclusionsCEUS can improve detection of hepatic metastases.