[Objective] To observe the clinical effect of revised Duhuo Jisheng Decoction and combining therapy on scapulohumeral periarthritis. [Method] Select 150 cases for research data, among which, 50 cases were treated with Duhuo Jisheng Decoction and combining therapy as treatment group, other 100 cases with only combining therapy as control group, 15d as a course;compare their effects after 2 courses. [Result] After treatment, the comparison of pain VAS scores between the 2 groups, the difference was of statistical meaning( P<0.05); The cure rate and effective rate were respectively 78.00% and 92.00%,and for other group, they were respectively 60.00%and 85.00%;the treatment group was better than other group, the difference was of statistical meaning.[Conclusion] Revised Duhuo Jisheng Decoction and combining therapy treating scapulohumeral periarthritis pays attention to internal arghralgia treatment, and the superficial as wel , with definite cure effect, worthy emphasizing and promotion for basic hospitals.

The author expounds his views on some queries about the integrated management of rural health services. ①The prospective goal of the integrated management is not to solve problems in the internal reform of township public health centers, but to implement management of health services at the village level, a goal that can be attained. ②The structure of property rights of rural health institutions ought not to become the criterion of rural health reform; what should become the criterion ought to be the establishment of safe, effective, comprehensive, and non profitable health services. ③Concrete analyses should be made regarding the increase of charges for medical services after the integrated management. ④The integrated management means management based on integration, the latter being an indispensable means of the former. ⑤Perfection of the integrated management needs to go through a process.

The main factor is the number of patients, which predicted by least square method to reduce the deviation. The like equipments located nearby are also considered and the Shared Coefficient is proposed.

Pulmonary hypertension has now become a common diseases threaten to human health .There are many factors that can cause pulmonary hypertension , such as heredity, immune injury, inflammation and endothelial function damage , etc.In recent years, studies have found that patients with pulmonary hypertension commonly have the phenomenon of iron deficiency , and intravenous iron agent can improve that , but the specific mechanism is unclear .Iron in the human body mainly is controlled by a protein called hepcidin, it inhibits iron flow from the gastrointestinal to the blood .Thus, intravenous iron administration can provide new options for the treatment of pulmonary hypertension .This paper reviews the progress of the iron deficiency and pulmonary hypertension .

Objective To investigate the role of platelet-derived growth factor-β receptor (PDGFR-β) in self-renewal of neural stem cells (NSCs).Methods In this study,NSCs of subventricular zone were isolated and cultured from PDGFR-β knockout (PDGFR-β-/-) mice of postnatal day 1 (P1) and P28;the number and diameters of secondary neurospheres were calculated;using 5-bromo-2-deoxyuridine (BrdU) incorporation assay and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay,cell proliferation and survival rates were analyzed;gene expression profiles were determined by PCR-array analyses;the effect of brain-derived neurotrophic factor (BDNF) on secondary neurospheres formation was examined in these cells.Results In PDGFR-β-/-NSCs,stem cell activities,such as number (/well;P1:25.9±1.3vs117.6±3.6,t=4.236,P＜0.01;P28:13.8± 0.7vs 19.8±0.6,t=2.116,P＜0.01)and diameters (μm;P1:67.7±1.9 vs 69.1 ±2.0,t=3.211,P＜0.01;P28:33.4±0.8vs37.8±0.8,t=2.354,P ＜0.01) of secondary neurospheres,cell proliferation (％;P1:73.3 ± 2.7 vs 88.7 ± 3.6,t =2.773,P ＜ 0.05;P28:28.6 ± 9.6 vs 68.2 ± 4.5,t =6.302,P ＜ 0.05) and survival rates (％;P1:14.5 ±2.1 vs 9.3 ± 1.3,t =7.222,P ＜ 0.05),were significantly lower as compared with age-matched controls.In comparison of the same genotypic NSCs,the decrease of secondary neurosphere formation was more striking in P28 NSCs than in P1 NSCs.PCR Array analyses demonstrated that expressions of fibroblast growth factor2 and BDNF were decreased (-2.04 ± 0.25,t =2.653,P ＜ 0.05;-3.24 ± 0.37,t =1.324,P ＜ 0.05),and Noggin (2.31 ± 0.37,t =2.749,P ＜ 0.05) was increased in P1 PDGFR-β-/-NSCs as compared with P1 controls.Addition of BDNF rescued the number and diameter of secondary neurospheres in P1 PDGFR-β-/-NSCs to similar levels as controls.Conclusions PDGFR-β signaling may play a role in the selfrenewal and proliferation of NSCs.BDNF may be involved in the effects of PDGFR-β signaling in these cells.

High-intensity focused ultrasound (HIFU) is a newly-developed noninvasive technique recently. Being a safe, non-radioactive and reproducible therapy, high-intensity focused ultrasound has been extensively used in the clinical treatment for a variety of solid tumors such as uterine adenomyosis. This paper aims to make a comprehensive review about this technique, focusing on the mechanism, clinical indications and contraindications, safety, efficacy and the complications of HIFU for the treatment of uterine adenomyosis.

Objective To investigate the scavenging effect of Baoyuan anticancer oral solution on superoxide anion (O-2 ) and 1,1-diphenyl-2-picrylhydrazyl hydrate(DPPH) free radicals. Methods O-2 and DPPH were examined with the ESR (electron spin resonance) spin trapping method. Results The scavenging effect of Baoyuan anticancer oral solution diluted to 50 fold, on O-2 and DPPH free radicals was 81. 32% and 98. 47% , respectively. Conclusion Baoyuan anticancer oral solu-tion has a dose-related effect on free radical elimination.

OBJECTIVE: To study the effect of salvianolate on the migration of endothelial cells induced by monocytes. METHODS: Transwell-boydom system was used to test the migration of endothelial cells induced by monocytes. Enzyme-linked immunosorbent assay (ELISA) and RT-polymerase chain reaction (RT-PCR) method were used to determine the effect of salvianolate on the expression of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) and their mRNA of monocytes. RESULTS: The migration of endothelial cells induced by monocytes was facilitated by salvianolate, compared with the control. After the monocytes were treated by salvianolate for 24 hours, the expression of mRNA of VEGF and bFGF was significantly up-regulated, and the expression of VEGF and bFGF was increased. CONCLUSION: The facilitation of salvianolate on the migration of endothelial cells induced by monocytes was observed. Salvianolate stimulates the expression of VEGF and bFGF and their mRNA of monocytes, and salvianolate may have the role of inducing migration of endothelial cells by working on these two factors.

The paper reviewed and analyzed the literature in the past five years about the function of the cells and mediums in the liver, and the influence and mechanism of traditional Chinese drug therapy on experimental liver fibrosis. It reveals that the traditional Chinese drug therapy treats experimental liver fibrosis through lots of mechanisms. The author gives also some suggestions on the further research into liver fibrosis.