After the reading behaviors ( reading altitude, reading frequency, reading habits and reading types) of 141 students in medical school were investigated and analyzed, the efficiencies of literature retrieval teaching in classroom were summarized, and the future direction was proposed.

OBJECTIVE: To study the preventive and therapeutic effect of Weitong injection(WTI) on the postoperative intestinal adhesion of rats.METHODS: Forty SD rats were randomly divided into five groups: blank control group,model control group,Dexamethasone group and high-dose WTI group and low-dose WTI group.Postoperative intestinal adhesion model was established in all the rats except those in the blank control group.On the operative day,the blank control group and the model control group received Normal saline(1 mL?kg-1);the Dexamethasone group received Dexamethasone(5 mg?kg-1),and WTI group received WTI(4 mg?kg-1 and 2 mg?kg-1,respectively) all via vena caudalis for 7 consecutive days.On day 8,laparotomy was performed on the rats for the evaluation of the degree of intestinal adhesion and the tissue of cecum was collected for the determination of the content of hydroxyproline(Hyp) and the pathological section test.RESULTS: The degree of postoperative intestinal adhesion of rats was attenuated by WTI(either high dose or low dose) or Dexamethasone.Furthermore,WTI significantly reduced the Hyp concentration in cecum tissue of rats with intestinal adhesion(P

Objective To explore the risk factors analysis of patients with hemorrhagic stroke in Zhongshan district of Dalian city in order to providing the Corresponding intervention measures.Methods From Oct 2010 to Aug 2013,183 cases of patients with hemorrhagic stroke(age ＞ 60 years old) and 158 cases healthy physical people in Zhongshan Hospital Affiliated to Dalian University were served as observation group and control group.Clinical information and life habit of two groups were recorded,the height and weight were measured,body mess index (BMI) was calculated,blood lipid level and plasma fiber protein level were detected.Results The rate of male,age ＞70 years,BMI index ≥25 kg/m2,smoking,history of hypertension,TG ≥ 1.7 mmol/L,TC ≥ 5.7 mmol/L,fibrinogen ＜ 4.0 g/L in observation group were 68.85 ％ (126/183),65.03％ (119/183),61.75％ (113/183),77.05％ (141/183),32.24％ (59/183),51.37％ (94/183),62.30％ (114/183),68.31％ (125/183) respectively,higher than those of control group (51.90％ (82/158),44.94％ (71/158),39.87％ (63/158),17.72％ (28/158),18.99％ (30/158),29.11％ (46/158),36.08％ (57/158),82.91％ (131/158),the differences were statistically significant (x2 =8.725,27.167,12.742,95.064,5.825,14.056,18.478,7.314,P ＜ 0.05).However,there were no significant differences in terms of diabetes history,drinking,high density lipoprotein-cholesterol level and low density lipoprotein-cholesterol between two groups.Conclusion Hemorrhagic stroke is closely related to many factors.Sex,age ＞ 70 years,smoking,obesity,history of hypertension,high cholesterin (TC ≥ 5.7 mmol/L) are independent risk factors of patients with hemorrhagic stroke in elderly.Through the control target population's blood pressure and blood lipids,rational diet,appropriate exercise,quit smoking and alcohol,adjust the good point of view,we can prevent the occurrence old hemorrhagic stroke.

Objective To recognize normal sinus rhythm (NSR), ventricular tachycardia (VT) and ventricular fibrillation (VF) from each other accurately and promptly. Methods A nonlinear descriptor based on multi-scale analysis, Hurst index, as a feature to quantify the nonlinear dynamics behavior of the ECG signal, was quoted in this paper. Results The nonlinear technique, Hurst index was examined and evaluated with ECG signals extracted from MIT-BIH Arrhythmia Database, MIT-BIH Malignant Ventricular Ectopy Database, and CU Ventricular Tachyarrhythmia Database under a specific moving-window length. The experiment showed good performance of this nonlinear descriptor. When the window length was 5 s long, the recognition accuracy for each of NSR, VT and VF was 100%. Besides, the computing speed was much faster than the speed obtained with a traditional non-linear technique, the complexity measure algorithm. Conclusion The Hurst index has a strong potential for life-threatening ventricular arrhythmia recognition in clinical applications.

OBJECTIVE:To reduce dispensing errors in Pharmacy intravenous admixture service(PIVAS),improve compound-ing quality of transfusion and guarantee the safety and rationality of clinic transfusion. METHODS:The case tracking method was applied to analyze each link of the work in PIVAS to find the reasons of configuration errors and control risk;and then the system tracking method was applied to analyze the hidden safety risk and the crack of quality from the inside of the system and work flow. Countermeasures and supporting continuous improvement were established to evaluate the effect of management before and after 6 months. RESULTS:Tracer methodology(TM)was adopted to find out the weakness in the key link and work flow of the cause of the configuration errors,the relative work pattern and work environment was improved,the relative system was formulated and completed,strength of rewards and punishment was increased. Through the implementation of the countermeasures,the number of dispensing errors was reduced from 81 to 38,and the error rate was reduced from 0.035% to 0.011%(P<0.01). CONCLU-SIONS:TM can be adopted in the key link and work flow of the cause of the configuration errors,aim at formulate and strictly carry out relative countermeasures to reduce errors in PIVAS,and promote the safety of drug use.

Adult ; Female ; Health Status ; Humans ; Male ; Middle Aged ; Occupational Exposure ; prevention & control ; Physical Examination ; Physicians ; Radiation Injuries ; prevention & control

In recent years,many breast cancer therapeutic vaccines have been entered several clinical trials,which bring a new promising treatment for breast cancer.These trials reveal the advantages and characteristics of tumor-associated antigens,and put forward the questions waiting to be solved.

Many studies had shown that the stigma is the important factor for diagnosis,treatment and re-covery of bipolar disorder.The stigma not only has negative effects on the patients and also on the marriage,fami-lies,study,work,medication treatment,and many other aspects.This paper reviews the development of definition of stigma,the characteristics,effects,interventions of stigma of bipolar disorder,finally,make a summary and put for-ward the prospects.

Objective To explore the influence of Lipo PGE1 on endothelin (ET-1) and interleukin (IL-6) in exhaled breath condensate(EBC) of patients with chronic obstructive pulmonary disease (COPD) and pulmonary hypertension(PH) and its clinical significance.Methods A total of 40 cases of patients with COPD and PH were randomly divided into thecontrol group and the treatment group,20 cases in each group.The control group was administered with the conventional treatments such as anti-infection,bronchodilator,antiasthma,expectorant and oxygen therapy;the treatment group was administered with Lipo PGE1 (10 μg/d,iv,for 10 days) besides the conventional treatments.ET-1 and IL-6 in EBC,pulmonary artery systolic pressure(PASP),arterial blood PaO2 and PaCO2,lung function FEV1/FVC,FEV1%pred in both groups were assayedbefore and after the treatment.Results There were no statistical difference between the two groups in the ET-1 and IL-6 in EBC,PASP,arterial blood PaO2 and PaCO2,FEV1/FVC,FEV1% pred before the treatment.After the treatment,the ET-1,IL-6 in EBC,PASP and arterial blood PaCO2 of the treatment group were lower than thoseof the control group (P<0.05);the arterial blood PaO2,FEV1/FVC,FEV1% pred of the treatment group were higher than those of the control group (P<0.05);The levels of ET-1 and IL-6 in EBC wereboth positivelycorrelated with PASP in the two groups.Conclusion Lipo PGE1 can reduce the levels of ET-1 and IL-6 in EBC of patients with COPD and PH.ET-1 and IL-6 may become a curative effect judgment index of COPD and PH,which has a certain clinical significance.

Cardiovascular Diseases ; psychology ; Humans ; Life Style