Adolescent ; Humans ; Lung ; diagnostic imaging ; pathology ; Lung Neoplasms ; diagnostic imaging ; pathology ; surgery ; Male ; Papilloma ; diagnostic imaging ; pathology ; surgery ; Pneumonectomy ; methods ; Tomography, X-Ray Computed

Objective To analyse the differences between idiopathic and symptomatic childhood epilepsy with occipital patoxysms. Methods The medical records of 38 patients with interictal spikes and/or sharp waves over occipital areas,posterior temporal-parietal areas,or both were retrospectively analysed.Epidemiological data,ictal symptoms,electroencephalogram,neuroimaging studies,treatment response and prognosis were compared using chi-square test or Mann-Whitney U test. Results Four patients of idiopathic group had positive family history related to nervous system.Seizures were more frequent in symptomatic group than in idiopathic group.Both groups showed autonomic symptoms,while ictal vomiting and deviation of eyes were more common in the presence of Panayiotopoulos type.The prognosis of idiopathic group was much better than that of symptomatic group. Conclusion Panayiotopoulos syndrome is more common.Neurologic deficits and electroencephalographic characteristics are major factors to predict seizure remission in children with occipital lobe epilepsy.Idiopathic childhood epilepsy with occipital paroxysms may result in better prognosis.

Early recognition of severe sepsis and septic shock,early initiation of effective interventions,implementation of early goal-directed therapy may be key approaches for reducing the mortality and improving the prognosis.This article focused on the staging diagnosis systems for sepsis (PIRO sepsis classification system) and the systematic early warning or rapid response system.We also discussed the diagnostic value of biomarkers,proteomics and metabolomics in sepsis and severe sepsis.No single marker as golden standard has emerged that can provide clinicians with all the information they need for early recognition of sepsis.Therefore,we suggested that clinicians should have even more reason to combine the sepsis symptoms,signs and biomarkers for a comprehensive evaluation,and that they needed to dynamically monitor the changes in these parameters,in order to make reasonable clinical decisions and strategies.

Objective To investigate the relationship between serum hepatitis B virus markers (HBV-M ) and HBV-DNA . Methods Enhanced chemiluminescence enzyme immunoassay (ECLIA ) and real-time fluorescent quantitative polymerase chain re-action(FQ-PCR) were employed to detect HBV-M and HBV-DNA in 262 serum samples ,respectively .HBV surface antigen(HB-sAg) ,anti-HBV surface antibody(HBsAb) ,HBV e antigen(HBeAg) ,anti-HBV e antibody(HBeAb) ,anti-HBV core antibody(HB-cAb) were included in HBV-M .Results Compared the positive rates of HBV-DNA ,HBsAg ,HBeAb in HBeAg-negative patients with those in HBeAg-positive patients ,the differences were statistically significant (P< 0 .01) .29(36 .7% ) patients with HBV-DNA logarithm value not less than 5 were found in HBeAg-negative patients .Differences of HBeAg ,HBeAb positive rates among patients with different ages were statistically significant (P<0 .01) .25 patients with HBsAg less than 250 IU/mL were found in HBV-DNA-positive patients ,12(48 .0% ) of which showed HBV-DNA logarithm value not less than 5 .HBV-DNA logarithm value of HBV-DNA-positive patients was positively correlated to HBeAg and HBeAb (r= 0 .542 ,0 .607 ,P< 0 .01) .Conclusion Com-bined detection of HBV-M and HBV-DNA contributes to estimating the HBV infection .

Many problems have been found in the inspection of assets in universities conducted　by the Ministry of Finance,Accordingly,some measures were taken to solve the problems,and as a　result the management was enhanced and the efficiency of the assets were improved.The author,　working in the front line of the inspectiong,reported the experience and in-depth reflection over the　experience to propose for the management of laboratories in medical colleges.

In this experiment,the bone marrow cell of C_(57) species of purity rat is used as a material and the micronucleus is used as an index,the prescriptions of Shengmai Powder,etc.were continuesly studied under the basis of some tonic prescription study.The result indicated the Shengmai Powder showed the inhibition on micronueleus induced by cyclophosphamide.

Objective To evaluate the application value of the hematology analysis combined with genetic diagnosis in the prena-tal diagnosis of thalassemia.Methods 2 368 parturients were performed the prenatal diagnosis of thalassemia in the prenatal diag-nosis center of our hospital from July 2010 to April 2013,and those with positive hematological screening detection were performed the genetic diagnosis.Results The hematology analysis results showed 124 parturients of abnormal HbA2.The hematology analy-sis results in the abnormal parturients had the statistical difference compared with those in the rest healthy parturients (P <0.01). Among 124 pregnant women of hematological positive phenotype,there were 16 couples with the same genotype,in these 16 preg-nant women,15 cases were performed the prenatal diagnosis of thalassemia,there were 7 cases of αthalassemia gene,2 cases of βgenotype,6 cases of normal genotype,3 cases of severe fetal thalassemia,including 2 cases of α-thalassemia(genotype--SEA/--SEA ),1 case ofβ-thalassemia(genotype 41-42/IVS-Ⅱ-654).All pregnant women terminated pregnancy after informing the patients.Conclu-sion The hematology analysis combined with genetic diagnosis plays an important role in the construction of perfect thalassemia prenatal detection and diagnosis intervention mode,and is worthy of popularization and application.

Objective To investigate the application value of fluorescence in situ hybridization (FISH)in prenatal diagnosis and compared with karyotype analysis of cells from amniotic fluid.Methods A total of 183 high-risk pregnant women received for a FISH and karyotype analysis who taken prenatal disgnosis in Meizhou people′s hospital between April 2012 and November 2013. Results According to the test results of karyotype analysis.There were 9 cases of chromosomal abnormality in 183 pregnant women.Among 9 cases,3 cases were trisomy 21,3 cases were trisomy 18,2 cases were XO and one case of XXY.One case of tri-somy 18 was showed normal using the FISH.Other cases were consistent with karyotype analysis result.Conclusion FISH is a rapid,reliable and prompt prenatal diagnosis method,combined with karyotype analysis will maximize the detection efficacy in pre-natal diagnosis of chromosome abnormalities.

Thirty-one cases of infant respiratory tract infection were treated by no-pain health-care Tuina plus medicated bath. Since the therapeutic effects were satisfactory, so parents and infants are willing to accept.

In order to evaluate appropriately the role of lipid metabolism by the refined konjac meal (RKM), a new source of dietary fiber, the effects of RKM on the level of serum and liver lipids, hepatic histopathology and on the composition and output of fecal bile acids in comparison with pectin, algin and agar were studied.The RKM contained about 75-80% of glucomannan. All four kinds of dietary fiber "were given at a level of 5% in the diet to the young male Wistar rats fed on a lipid-rich diet containing 5% lard, 1% cholesterol and 0.25% chplate. The control group was fed on a lipid-rich diet alone withput fiber. The normal group was fed on a basal diet without extra lipid added. Feeding period was 9 weeks.The results obtained were as follows;1)All the dietary fibers tested have the similar effects on serum lipid composition. At the end of 2-week of the experiment, the serum total cholesterol levels of the four experimental groups were only 62% to 75% of that of the control group, and at the end of 7-week they were lowered to the same level of the normal group. The level of the triglyceride in serum did not change in all groups during the experiment.2)Relative liver weights were lower in four experimental groups than in control group. Hepatic hisiopathological examinations showed lipotropic effect in RKM, pectin and algin groups. Both of the above effects appeared most significantly in RKM group. The concentrations of total cholesterol and triglyceride in liver in RKM group were lower than those in control group as well as other three experimental groups.3)No harmful effects on the intake of food and growing of rats were found when feeding these four kinds of dietary fiber at the level of 5%.4)The daily output of fecal bile acids (CDCA + GDCA) was significantly increased in four experimental groups.The increase of fecal output of bile acids, especially CDCA, may be one of the mechanisms of hypocholesterola-emic effect of dietary fibers.It could be concluded that RKM has the same significant hypocholestero-lemic effect as the pectin, algin and agar, but its lipotropic effect is more potent.