1.Diagnosis of anterior bundle injury of medial collateral ligament after elbow dislocation with 3 .0T MRI
Jingwu YU ; Guoxin SHEN ; Jie NG TA ; Yongqiang YE ; Jinlan NG HUA ; Yu SHEN ; Xiaohui NG WA
Journal of Practical Radiology 2016;32(5):761-763
Objective To apply 3 .0T MRI in diagnosing injuries of anterior bundle of medial collateral ligament after elbow dislo‐cation .Methods The MRI features of the injuries of medial collateral ligament anterior bundle were analyzed retrospectively in 20 patients with elbow dislocation .The coronal ,sagittal ,axial and lamina oblique coronal were scanned routinely with SE T1WI ,T2WI‐FS sequences .Results Varying degrees of anterior bundle injuries of medial collateral ligament were observed in all the 20 patients ,in‐cluding the mild injury(n=8) ,part avnlsion(n=5) ,completely rupture(n=7) .Furthermore ,concomitant injuries including lateral collateral ligament(n=11) ,ringlike ligament(n=5) ,flex/stretch muscle tendon(n=9) ,and the fracture(n=7) were also observed . Conclusion The injuries of medial collateral ligament anterior bundle after elbow dislocation could be diagnosed accurately with 3 .0T MRI and the degree of injuries could also be defined on image .The 3 .0T MRI could be recommended as regular examination to pa‐tients with elbow dislocation .
2.Study on correlation between single b-value and multiple b-value DWI and different types of breast lesions
Gaoyan NG WA ; Haibo DONG ; Jie NG WA ; Lihui FU ; Bo NG WA ; Shiyong CHEN
Journal of Practical Radiology 2017;33(12):1855-1858
Objective To investigate the relationship between single b-value and multiple b-value diffusion weighted imaging (DWI)and different types of breast lesions.Methods The data of 92 cases including 8 cases of cyst,11 cases of granulomatous inflammation,33 cases of benign nodules lesions and 40 cases of malignant tumor were analyzed retrospectively,who underwent single b-value DWI and multiple b-value DWI and all patients were confirmed by pathology.The normal side of the mammary gland fiber was taken as the control group.Apparent diffusion coefficient(ADC)were obtained by the monoexponential model.Slow apparent diffusion coefficient(ADCslow),fast apparent diffusion coefficient(ADCfast),the fraction of fast ADC(ffast)were obtained by the biexponential model.ADC,ADCslow,ADCfast,ffastvalues of different breast lesions were analyzed by single factor analysis of variance.The LSD-t test was used to compare the mean values of the parameters of the breast lesions in pairs.Results The ADC and ADCslowvalue of breast lesions were decreased in the order of cyst (2.369 ± 0.380)×10-3mm2/s,(1.294 ± 0.439)×10-3mm2/s,normal gland(1.785 ± 0.298)×10-3mm2/s,(0.946 ± 0.321)×10-3mm2/s,benign tumor(1.647 ± 0.296)×10-3mm2/s,(0.944 ± 0.256)×10-3mm2/s,malignant tumor(1.146 ± 0.191)×10-3mm2/s,(0.584 ± 0.139)×10-3mm2/s and mastitis(1.062 ± 0.231)×10-3mm2/s,(0.567 ± 0.115)×10-3mm2/s.The ADCfastvalue of malignant group(4.445 ± 1.616)×10-3mm2/s was significantly higher than that of other groups,and the difference was statistically significant.The ffastvalue of malignant group 0.364 ± 0.148 was significantly lower than that of benign group,normal gland and cyst.ADCfastvalue in the inflammatory group(3.321 ± 0.660)× 10-3mm2/s was significantly lower than that in the malignant group,and the difference was statistically significant.There was no significant difference in ADC,ADCslowand ffast.Conclusion Compared with the single b-value DWI,the parameters of multiple b-value DWI reflected the pathological features of different breast lesions better.The value of ADCfasthas higher diagnostic value in the identification of mastitis and breast cancer.
3.Effects of Preemptive Analgesia with Parecoxib Sodium on the Differentiation of Peripheral T Helper Cells in Patients with Radical Mastectomy
Yangcheng YAO ; Jie NG ZHA ; Jingming CHEN ; Shiqing NG WA
Chinese Journal of Clinical Medicine 2014;(3):316-318
Objective:To observe the effects of preemptive analgesia with parecoxib sodium on differentiation of peripheral T helper cells(Th) in patients with radical mastectomy .Methods :A toal of 50 patients with radical mastectomy were randomly di-vided into parecoxib group(Group P) and the control group(Group C) .Parecoxib sodium(40 mg ,diluted with normal saline into 5 mL ,the same below ) was intravenously injected 1 h before operation in Group P ,and 12 h after the first injection .The same dose of normal saline was intravenously injected in Group C at the same time-point .Patient-controlled intravenous analgesia (PCIA) with fentanyl had implemented in two groups after operation .The levels of interferon-γ(IFN-γ) ,interleukin-4(IL-4) in Th1 and Th2 were measured by flow cytometry before anesthesia(T0) ,2 h(T1) ,12 h(T2) ,24 h(T3) ,48 h(T4)after operation in the two groups .Th1 cell was marked by CD3+ CD8- IFN-γ+ .Th2 cell was marked by CD3+ CD8- IL-4+ .Th1/Th2 was calculated by the level of IFN-γ+ /IL-4+ .The visual analogue scale (VAS) ,Bruggemann comfort scale(BCS) ,dosage of fenta-nyl at each time-point in two groups were compared .Results:VAS scores in group P were significantly lower than those in Group C at T2 ,T3 ,T4 .BCS scores at T1 ,T2 ,T3 in group P were significantly higher than those in Group C .The dosages of fentany at T2 ,T3 in Group P were significantly lower than those in Group C .Compared with T0 ,Th1/Th2 ratios in the two groups at T2 ,T3 ,T4 were lower(P<0 .05) .Th1/Th2 in Group P was higher than those in Group C at T2 ,T3 ,T4(P<0 .05) . Conclusions :Th1/Th2 in patients decreases after radical mastectomy .Preemptive analgesia with parecoxib sodium assisted with fentanyl PCIA can inhibit the shift of the balance of Th1/Th2 towards Th2 type .