Objective To present a new seriological method for diagnosing breast carcinoma.Methods Seral anti-p53 antibody was detected with immuno-polymerase chain reation(Immuno-PCR).The expression of p53 in tissue was detected with enzymeimmu-nohistochemistry technique.Results The positive rate of anti-p53 antibody in serum of breast carcinoma was 39.5% and anti-p53 antibody was not found in non-carcinoma and normal controls.The positive rate of anti-p53 antibody was higher than that of non-carcinoma and normal controls(P

Objective To discuss the change and the regulation of tumornecrosis factor(TNF-?) and epidermal growth factor(EGF) before and after extracorporeal shock wave lithotripsy.Method Radioimmunoassay was used to measure TNF-? in 50 cases urine sample before and after ESWL.Results TNF-? level in urine after ESWL were increased significantly at 1～4d(t=2.82,P

Objective To compare the content of total flavonoids in Herba Scutellarlae Barbatae derived from different places.Method UV metric method was used to determine the contents of total flavonoids of Herba Scutellarlae Barbatae from different regions.Result The contents of total flavonoids in Herba Scutellariae Barbatae derived from Nantong Jiangsu,Juaoling Guangdong,Lixin Anhui,Huaning Hunan, Mojiang Yunnan,Yongding Fujian,Nanchang Jiangxi,Longsheng Guangxi,Honghu Hubei and Qingyuan Zhejiang were 4.16%,3.55%,2.89%,2.78%,2.41%,2.22%,2.16%,1.98%,1.61% and 1.51%,respectively. Conclusion The content of total flavonoids in Herba Scutellariae Barbatae from different places is quite different,and the highest is the one from Nantong Jiangsu.

Exterior-and interior-meridian acupoints were used, mainly by selection of local acupoints along meridian. According to the state of disease, electroacupuncture and acupoint injection were combined to treat brachial plexus injury. Among 12 patients, 6 cases were basically cured, 4 cases got effectiveness and 2 cases had no effectiveness. The therapeutic effect of exterior- and interior-meridian acupoints in brachial plexus injury was satisfactory.

Hematopoietic stem cell transplantation (HSCT) has become the frontline therapy for patients with multiple myeloma (MM), and for young patients with primary MM, early autologous stem cell transplantation (ASCT) is a standard treatment. In the era of novel drugs, the application of new pharmaceutics in the consolidation and maintenance therapy before and after HSCT can improve the efficacy of HSCT. The novel agents pose a challenge to the status of HSCT in relapsed and refractory myeloma. This article summarizes the recent clinical studies of HSCT in the era of novel agents to clarify the role of HSCT in treatment of MM.

This paper introduced the risk communication principles made by WHO including: establishing trust, releasing information betimes, keeping transparent , listening to the public opinions and involving them in etc.Seven steps to make a two -way and interactive communication are also put up on that basis .It covers infor-ming the medial information and comforting patients ’ anxiety.In addition, the strategies of informing the patients of high-risk medical issues or low -risk medical issues and good or bad news are also mentioned .

Pathological myopia(PM)is one of the global leading causes of blindness because of its severe optic complications.Previous researches implicated that hereditary factors play crucial roles in the pathogenesis of PM,and plenty molecular genetic studies,such as gene mapping and candidate gene screening,have been done to identify gene loci linked to PM.The newest advances in molecular genetic study on pathological myopia relevant gene loci were reviewed,including non-syndrome PM and system disease associated with PM.

Objective The purpose of this study is to investigate CD 46 expression in advanced invasive breast cancer and in normal breast tissues , and to analyze the correlation between CD 4 expression and effect of neoadjuvant chemotherapy ,exploring its clinical significance for the prognostic value of neoadjuvant chemotherapy in breast cancer .Methods Immunohistochemistry was employed to detect CD 46 expression of tissue samples from 60 patients with invasive breast cancer and 30 normal breasts .We further analyzed the relationship between effect of neoadjuvant chemotherapy and CD 46 expression ,and the prognostic significance for the survival .Rseults CD46-positive rate in breast cancer was apparently higher than that in normal breast tissues (81.67% vs. 46.67%,P<0.05).After neoadjuvant chemotherapy,the CD46 expression was significantly decreased (P <0 .05).There was a negative correlation between CD 46 expression and efficacy of chemotherapy ( P<0.05). CD46 expression in breast cancer could be affected in cancer invasion ,lymph node metastasis(P<0.05).Con-clusion CD46 expression in breast cancer patients is higher than that in healthy people ,and was negatively cor-related with efficacy of adjuvant chemotherapy .The increasing rate of CD 46 positive expression has predictive val-ue for the poor prognosis of patients .

Objective To compare the efficacy of two different surgery incisions on original corneal astigmatism in cataract surgery. Methods 300 patients (300 eyes) of cataract surgery from August 2012 to August 2013 in our hospital were included in the study,of which 150 patients in the observation group treated with transparent cornea incision in the steep axis of astigmatism,and the control group of 150 pa-tients received lateral ( right) or on the nose by the temporal side ( left) transparent cornea incision. Results In the third day,first month, third month,sixth month and 12th month after surgery,the average corneal astigmatism in the observation group was significantly lower than that before the surgery,which after a month the lowest ( +0. 79 ± 0. 92)D;average corneal astigmatism of patients in the control group were significantly higher than that before the surgery,corneal astigmatism after 3 days to reach the highest,( -5. 65 ± 0. 89)D,3 days after sur-gery,1 month, 3 months, 6 months and 12 months,patients in the observation group were significantly higher visual acuity patients,the differ-ence was statistically significant (P<0. 05). Conclusion Phacoemulsification clear corneal incision along the steep axis IOL implantation for cataract surgery can correct astigmatism original extent a certain extent,and to promote the recovery of visual acuity in patients with a grea-ter degree.

OBJECTIVE: To study of effects of dexarmethasome of Jianlishu Powder on the release of tumor necrosis factor-? in rats of adjuvant arthritis model. METHODS: Adjuvant-induced arthritis (AIA) was induced by injection of frenndi's complete adjuvant in rats' plantar to observe the effects of Jianlishu Powder on rice' hypersensitivity reaction, thickness of inflamed plantar of both feet, and levels of tumor necrosis factor-?(TNF-?), Interleukin-2 (IL-2) and circulating immune complex (CIC) in AIA rats. RESULTS:rats' right posterior metatarsus which was injected with adjuvant was swollen from the second day for 15 days (primary lesion). Jianlishu Powder significantly inhibited feet swelling induced by collagen dose-dependently and down-regulate the contents of TNF-?,IL-2 and CIC thus resulting in an anti-inflammatory action in AIA rats(P