Adolescent ; Humans ; Lung ; diagnostic imaging ; pathology ; Lung Neoplasms ; diagnostic imaging ; pathology ; surgery ; Male ; Papilloma ; diagnostic imaging ; pathology ; surgery ; Pneumonectomy ; methods ; Tomography, X-Ray Computed

Objective To reveal the trend of change incidence of hepatitis A(HAV)in Shandong province and explore dynamic analysis methods.Method Dynamic analysis was made on data of hepatitis A in Shandong province from 1990 to 2006.Results The reported incidence of hepatitis A patients dropped from 53.97/100,000 to 1.14/100,000 in Shandong province from 1990 to 2006,which showed a marked downward trend;the groups under the age of 10 dropped from 55.60% to 5.12%,the average age of incidence moved from 14.40 years old to 40.19 years old.Conclusion The incidence of hepatitis A has been changed from prevalent to sporadic in Shandong province,and there was a further downward trend;the age of the high-risk population has been shifted to older age group;the sex ratio of incidence between males and females in the population above 10 years of age had an expansion trend,the age distribution curve differences between males and females was also expanded.

Humans ; Infant ; Infant Food ; Infant, Newborn ; Triazines ; toxicity ; Urinary Calculi ; chemically induced

Objective To study the surgical methods and surgical timing on Pilon fractures.Methods Retrospective analysis in accordance with fractures types and soft tissue damage degrees using different methods of internal fixation surgery for 20 eases of Pilon fractures.Results Clinical observation of all cases averaged 18 mouths,all bone healing,Ruediand-Allgawer Ⅰ type had a good rate of 100%,Ⅱ -type 80%,Ⅲ type 67%.Conclusions According to patient's age,general condition,fracture and articular surface of cartilage,the degree of soft tissue injury of different factors,we should select the appropriate surgical meth-ods and surgical timing for Pilon fractures to obtain a satisfactory outcome.

Medical Oncology ; trends

Biomarkers, Tumor ; analysis ; Diagnosis, Differential ; Diagnostic Errors ; Humans ; Irritable Bowel Syndrome ; pathology ; Lymphoma, B-Cell ; pathology ; Oncogene Proteins, Fusion ; analysis ; Sarcoma, Synovial ; chemistry ; pathology

Carcinoma, Neuroendocrine ; pathology ; Carcinoma, Pancreatic Ductal ; pathology ; Carcinoma, Papillary ; pathology ; Concept Formation ; Humans ; Neuroendocrine Tumors ; pathology ; Pancreatic Neoplasms ; classification ; pathology ; World Health Organization

Objective To observe the efficacy of comprehensive strategies in treating diabetic foot.Methods Thirty five cases with diabetic foot were treated by comprehensive strategies,including antiinfection,strict blood sugar control,vasodilatation,improvement of microcirculation,never nutrition,debridement and supportive care,etc.Results Among the 35 patients with diabetic foot,24 were recovered satisfactorily,7 cases were recovered with improvement,2 cases underwent amputation and 2 cases gave up further treatment.Conclusion Diabetic foot can be treated by comprehensive measures satisfactorily,with improved cure rate and low amputation rate.

Sepsis has become a widespread and very complex issue for modern critical care medicine.It is undoubtedly of great theoretical and clinical significance that we should strengthen the study of sepsis and explore new treatments and drugs.It has been found that curcumin had anti-tumor,anti-inflammatory,anti-virus,antibacterial,antioxidant and other pharmacological effects,low toxicity,and a good potential for clinical application.Moreover,it was thought to be potentially immunomodulatory in the last two decades.A number of experimental studies had elicited that curcumin could be used for sepsis and septic shock.This article reviews the immune regulation mechanism of curcumin in sepsis.

Capillary leak syndrome (CLS) is a common and life-threatening disorder in children.The common pathogenies are sepsis,severe trauma,shock,asphyxia,extracorporeal circulation,ischemical reperfusion injury and so on.It is characterized by shock resulting from leakage of plasma,which is refected by accompanying hemoconcentration,hypoalbuminemia and edema,sometimes followed by multiple organ dysfunction syndrome.Clinicians should consider the diagnosis in patients with unexplained edema and hypotension.To know the pathophysiology and clinical course will be benefit to proper medicine choosen.